robbieclark.bsky.social
@robbieclark.bsky.social
Reposted by robbieclark.bsky.social
A Perspective by @stephanieaw.bsky.social and @fraserlab.com discusses ways macromolecules use conformational entropy to control binding, catalysis, and allostery
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Advances in uncovering the mechanisms of macromolecular conformational entropy - Nature Chemical Biology
Protein conformational entropy plays a vital role in functions like binding and catalysis. This Perspective discusses three ways macromolecules use conformational entropy: prepaying entropic costs, re...
www.nature.com
April 25, 2025 at 3:35 PM
A Perspective by @stephanieaw.bsky.social and @fraserlab.com discusses ways macromolecules use conformational entropy to control binding, catalysis, and allostery
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by robbieclark.bsky.social
New study led by @georgiaisom.bsky.social and Ben Cooper. Sims by Robbie Clark. Exps & sims reveal phospholipid transport across the bacterial periplasm through the envelope-spanning bridge YhdP www.sciencedirect.com/science/arti... @dunnschool.bsky.social @oxfordbiochemistry.bsky.social
Phospholipid transport across the bacterial periplasm through the envelope-spanning bridge YhdP
The outer membrane of Gram-negative bacteria provides a formidable barrier, essential for both pathogenesis and antimicrobial resistance. Biogenesis o…
www.sciencedirect.com
December 7, 2024 at 6:30 PM
New study led by @georgiaisom.bsky.social and Ben Cooper. Sims by Robbie Clark. Exps & sims reveal phospholipid transport across the bacterial periplasm through the envelope-spanning bridge YhdP www.sciencedirect.com/science/arti... @dunnschool.bsky.social @oxfordbiochemistry.bsky.social
Reposted by robbieclark.bsky.social
In a multidisciplinary study led by Georgina Benn and Tom Silhavy we show the role of OmpA in controlling the organisation of the outer membrane and in sharing the mechanical load. www.pnas.org/doi/10.1073/....
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
www.pnas.org
December 4, 2024 at 10:07 PM
In a multidisciplinary study led by Georgina Benn and Tom Silhavy we show the role of OmpA in controlling the organisation of the outer membrane and in sharing the mechanical load. www.pnas.org/doi/10.1073/....