Rosi Fregel
@rfregel.bsky.social
Professor of Genetics and PI of the Paleogenomics Group at ULL (Canary Islands, Spain) working on ancient DNA of the Canarian human populations and more :)
Reposted by Rosi Fregel
I taught (and co-taught) a course on human population genetics from 2000-2024. Having retired, I'm now making all the course materials public: github.com/alanrogers/p... #popgen #evbio
GitHub - alanrogers/popgen: A course on population genetics
A course on population genetics. Contribute to alanrogers/popgen development by creating an account on GitHub.
github.com
November 27, 2025 at 7:10 PM
I taught (and co-taught) a course on human population genetics from 2000-2024. Having retired, I'm now making all the course materials public: github.com/alanrogers/p... #popgen #evbio
Reposted by Rosi Fregel
Despite my insomnia, I'm very happy to share our preprint: a multi-disciplinary assessment of a sheep mass mortality event from ~18th century France. We report the first ancient sheeppox virus (think smallpox) and the Taenia hydatigena (nasty roundworm) genomes.
#aDNA
#aDNA
Evidence of sheeppox in 17th-19th century France: a multi-disciplinary investigation of a sheep mass mortality assemblage
Epizootic outbreaks posed major threats to food security, economic stability, and animal welfare in past communities. While these events and their impacts are well documented in historical records, ve...
www.biorxiv.org
November 26, 2025 at 6:33 AM
Despite my insomnia, I'm very happy to share our preprint: a multi-disciplinary assessment of a sheep mass mortality event from ~18th century France. We report the first ancient sheeppox virus (think smallpox) and the Taenia hydatigena (nasty roundworm) genomes.
#aDNA
#aDNA
Reposted by Rosi Fregel
The middle-aged man had craniosynostosis -- premature fusion of three skull sutures -- which was typically fatal in childhood in the Medieval period. 🏺🧪
'I had never seen a skull like this before': Medieval Spanish knight who died in battle had a rare genetic condition, study finds
The extremely long skull of a medieval knight points to an underlying genetic condition.
www.livescience.com
November 25, 2025 at 12:54 PM
The middle-aged man had craniosynostosis -- premature fusion of three skull sutures -- which was typically fatal in childhood in the Medieval period. 🏺🧪
Reposted by Rosi Fregel
@alexgilardet.bsky.social et al. recovered ancient DNA from bovine bones in the Denisova cave to characterize Pleistocene bovine diversity, identifying the Altai Mountains as a hotspot for bovine diversity.
🔗 doi.org/10.1093/gbe/evaf206
#genome #evolution #aDNA #denisova
🔗 doi.org/10.1093/gbe/evaf206
#genome #evolution #aDNA #denisova
Paleogenomics Reveals a Loss of Bovine Lineages in Mid-latitude Asia Over the Last 200,000 Years
Abstract. Bovines have a complex yet poorly understood evolutionary history that is characterized by admixture and diversity loss during the Late Pleistoce
doi.org
November 24, 2025 at 9:31 AM
@alexgilardet.bsky.social et al. recovered ancient DNA from bovine bones in the Denisova cave to characterize Pleistocene bovine diversity, identifying the Altai Mountains as a hotspot for bovine diversity.
🔗 doi.org/10.1093/gbe/evaf206
#genome #evolution #aDNA #denisova
🔗 doi.org/10.1093/gbe/evaf206
#genome #evolution #aDNA #denisova
Reposted by Rosi Fregel
Exploration of hanging coffin customs and the bo people in China through comparative genomics 🧬☠️🇨🇳 www.nature.com/articles/s41...
Exploration of hanging coffin customs and the bo people in China through comparative genomics - Nature Communications
Hanging Coffins were a mortuary tradition practiced in southern China and Southeast Asia. Here, the authors show that different groups of ancient Hanging Coffin practitioners are genetically related, ...
www.nature.com
November 22, 2025 at 1:29 AM
Exploration of hanging coffin customs and the bo people in China through comparative genomics 🧬☠️🇨🇳 www.nature.com/articles/s41...
Reposted by Rosi Fregel
I'm thrilled to announce, together with @RajivBoscoloAgostini and @jack-the-villain.bsky.social, that our paper entitled "Fifteen millennia of human mitogenome evolution in Sicily" is out now in Science Advances!
Check it out!
doi.org/10.1126/scia...
Check it out!
doi.org/10.1126/scia...
Fifteen millennia of human mitogenome evolution in Sicily
Mitogenomes spanning 15 millennia reveal a genetic discontinuity within Sicily and continuous gene flow from Eurasia and Africa.
doi.org
November 14, 2025 at 7:52 PM
I'm thrilled to announce, together with @RajivBoscoloAgostini and @jack-the-villain.bsky.social, that our paper entitled "Fifteen millennia of human mitogenome evolution in Sicily" is out now in Science Advances!
Check it out!
doi.org/10.1126/scia...
Check it out!
doi.org/10.1126/scia...
Reposted by Rosi Fregel
🚨 New paper alert 🚨
Our research, published today in Science, reveals remarkable concordance between human and dog genomes through time, highlighting how deeply intertwined our evolutionary histories have been over the past 11,000 years.
🔗 Read the full paper here: www.science.org/doi/10.1126/...
Our research, published today in Science, reveals remarkable concordance between human and dog genomes through time, highlighting how deeply intertwined our evolutionary histories have been over the past 11,000 years.
🔗 Read the full paper here: www.science.org/doi/10.1126/...
Genomic evidence for the Holocene codispersal of dogs and humans across Eastern Eurasia
As the first domestic species, dogs likely dispersed with different cultural groups during the Late Pleistocene and Holocene. To test this hypothesis, we analyzed 73 ancient dog genomes, including 17 ...
www.science.org
November 13, 2025 at 10:48 PM
🚨 New paper alert 🚨
Our research, published today in Science, reveals remarkable concordance between human and dog genomes through time, highlighting how deeply intertwined our evolutionary histories have been over the past 11,000 years.
🔗 Read the full paper here: www.science.org/doi/10.1126/...
Our research, published today in Science, reveals remarkable concordance between human and dog genomes through time, highlighting how deeply intertwined our evolutionary histories have been over the past 11,000 years.
🔗 Read the full paper here: www.science.org/doi/10.1126/...
Reposted by Rosi Fregel
Check out our paper, we now included a comparison between glimse1 and glimpse2!
Our paper on imputation of ancient goat genomes is now available at GBE - congratulations to @jolijnerven.bsky.social #aDNA
Inferring Domestic Goat Demographic History Through Ancient Genome Imputation
Abstract. Goats were among the earliest managed animals, making them a natural model to explore the genetic consequences of domestication. However, a chall
academic.oup.com
November 11, 2025 at 9:01 AM
Check out our paper, we now included a comparison between glimse1 and glimpse2!
Reposted by Rosi Fregel
Become our colleague! - 2yr Postdoctoral position in Palaeo-population genomics at the Center for the Human Past (UU) @humanpastcenter.bsky.social 🧪
Great place to work at (ok, I am biased), integration with archaeologists and linguists + pretty flexible research topic
www.uu.se/en/about-uu/...
Great place to work at (ok, I am biased), integration with archaeologists and linguists + pretty flexible research topic
www.uu.se/en/about-uu/...
Postdoctoral position in Palaeo-population genomics at the Center for the Human Past - Uppsala University
Postdoctoral position in Palaeo-population genomics at the Center for the Human Past, Department of Organismal Biology, Uppsala University
www.uu.se
November 11, 2025 at 8:37 AM
Become our colleague! - 2yr Postdoctoral position in Palaeo-population genomics at the Center for the Human Past (UU) @humanpastcenter.bsky.social 🧪
Great place to work at (ok, I am biased), integration with archaeologists and linguists + pretty flexible research topic
www.uu.se/en/about-uu/...
Great place to work at (ok, I am biased), integration with archaeologists and linguists + pretty flexible research topic
www.uu.se/en/about-uu/...
Reposted by Rosi Fregel
Our paper on imputation of ancient goat genomes is now available at GBE - congratulations to @jolijnerven.bsky.social #aDNA
Inferring Domestic Goat Demographic History Through Ancient Genome Imputation
Abstract. Goats were among the earliest managed animals, making them a natural model to explore the genetic consequences of domestication. However, a chall
academic.oup.com
November 10, 2025 at 6:49 PM
Our paper on imputation of ancient goat genomes is now available at GBE - congratulations to @jolijnerven.bsky.social #aDNA
Reposted by Rosi Fregel
Are you interested in human evolution? Would you like to work in palaeoproteomics 👩🏻🔬 and live in Copenhagen 🇩🇰🚴🏽♀️? So, apply to these advertised positions. More info 👇
⚠️Just a quick reminder, there are a few days left to apply for these two positions in #palaeoproteomics.
I'm hiring!⭐ As part of the DFF Sapere Aude-funded project MiddleEarth, I am looking for 1 postdoctoral researcher and 1 research assistant.
November 5, 2025 at 2:48 PM
Are you interested in human evolution? Would you like to work in palaeoproteomics 👩🏻🔬 and live in Copenhagen 🇩🇰🚴🏽♀️? So, apply to these advertised positions. More info 👇
Reposted by Rosi Fregel
Are you obsessed with archaeological or historical questions and easily get into coding?
Or a computational scientist that want to understand biology and disease evolution, and curious about the ancient past?
If you have these or other burning questions that fits into our programme, apply below!
Or a computational scientist that want to understand biology and disease evolution, and curious about the ancient past?
If you have these or other burning questions that fits into our programme, apply below!
PhD-opening in our ancient genomics lab this year, apply below!
We work on:
📜 Genetic history integrated with archaeology and history
📈 Natural selection and trait genetics
🐺 Evolutionary genomics of dogs and wolves
🦠 Ancient pathogen genomics
💀 Hominin evolution and ancient proteomics
We work on:
📜 Genetic history integrated with archaeology and history
📈 Natural selection and trait genetics
🐺 Evolutionary genomics of dogs and wolves
🦠 Ancient pathogen genomics
💀 Hominin evolution and ancient proteomics
Motivated graduates with backgrounds in biological or biomedical sciences, physics, chemistry, mathematics, engineering and/or computer science are invited to apply to our 4-year fully funded PhD programme.
Apply by 05 November 2025
www.crick.ac.uk/careers-and-...
Apply by 05 November 2025
www.crick.ac.uk/careers-and-...
October 27, 2025 at 8:59 PM
Are you obsessed with archaeological or historical questions and easily get into coding?
Or a computational scientist that want to understand biology and disease evolution, and curious about the ancient past?
If you have these or other burning questions that fits into our programme, apply below!
Or a computational scientist that want to understand biology and disease evolution, and curious about the ancient past?
If you have these or other burning questions that fits into our programme, apply below!
Reposted by Rosi Fregel
DNA from Napoleon’s 1812 army identifies the pathogens likely responsible for the army’s demise during their Russian retreat. www.cell.com/current-biol...
Nicolás Rascovan & colleagues
@currentbiology.bsky.social
Nicolás Rascovan & colleagues
@currentbiology.bsky.social
October 24, 2025 at 3:00 PM
DNA from Napoleon’s 1812 army identifies the pathogens likely responsible for the army’s demise during their Russian retreat. www.cell.com/current-biol...
Nicolás Rascovan & colleagues
@currentbiology.bsky.social
Nicolás Rascovan & colleagues
@currentbiology.bsky.social
Reposted by Rosi Fregel
A hearty Denisovan stew ripe with stories of mixing and more mixing, even with a third more ‘archaic’ hominid.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
A high-coverage genome from a 200,000-year-old Denisovan
Denisovans, an extinct sister group of Neandertals who lived in Eastern Eurasia during the Middle and Late Pleistocene, are known only from a handful of skeletal remains and limited genetic data, incl...
www.biorxiv.org
October 20, 2025 at 7:07 PM
A hearty Denisovan stew ripe with stories of mixing and more mixing, even with a third more ‘archaic’ hominid.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Rosi Fregel
In a new paper led by Jiaqi Yang we trace the distribution of Denisovan introgressed DNA in ancient modern human genomes over time.
www.cell.com/current-biol...
www.cell.com/current-biol...
An early East Asian lineage with unexpectedly low Denisovan ancestry
Yang et al. study Denisovan ancestry in ancient and present-day humans. In contrast
to other East Asians, genomic comparisons suggest that the Jomon derived most of their
ancestry from a deep lineage ...
www.cell.com
October 20, 2025 at 7:39 PM
In a new paper led by Jiaqi Yang we trace the distribution of Denisovan introgressed DNA in ancient modern human genomes over time.
www.cell.com/current-biol...
www.cell.com/current-biol...
Reposted by Rosi Fregel
Very excited to share that our work assessing the genomic diversity of snow leopards has come out today in PNAS! Spoiler alert - they have the lowest genetic diversity of all big cats!
www.pnas.org/doi/10.1073/...
news.stanford.edu/stories/2025...
@petrovadmitri.bsky.social @elliecat.bsky.social
www.pnas.org/doi/10.1073/...
news.stanford.edu/stories/2025...
@petrovadmitri.bsky.social @elliecat.bsky.social
Exceedingly low genetic diversity in snow leopards due to persistently small population size | PNAS
Snow leopards (Panthera uncia) serve as an umbrella species whose conservation benefits
their high-elevation Asian habitat. Their numbers are belie...
www.pnas.org
October 7, 2025 at 9:10 PM
Very excited to share that our work assessing the genomic diversity of snow leopards has come out today in PNAS! Spoiler alert - they have the lowest genetic diversity of all big cats!
www.pnas.org/doi/10.1073/...
news.stanford.edu/stories/2025...
@petrovadmitri.bsky.social @elliecat.bsky.social
www.pnas.org/doi/10.1073/...
news.stanford.edu/stories/2025...
@petrovadmitri.bsky.social @elliecat.bsky.social
Reposted by Rosi Fregel
🦴🧬🦴🧬🦴
Abstract submission is now open for the 1st International Conference on Palaeogenomics!
June 23–26 2026, in Stockholm.
Join researchers from across the field for 4 days and >100 talks (+ poster sessions)!
Submit abstracts here 👉
icp2026.palaeogenomics.org/abstracts/
Deadline: Nov 30th
Abstract submission is now open for the 1st International Conference on Palaeogenomics!
June 23–26 2026, in Stockholm.
Join researchers from across the field for 4 days and >100 talks (+ poster sessions)!
Submit abstracts here 👉
icp2026.palaeogenomics.org/abstracts/
Deadline: Nov 30th
October 1, 2025 at 1:28 PM
🦴🧬🦴🧬🦴
Abstract submission is now open for the 1st International Conference on Palaeogenomics!
June 23–26 2026, in Stockholm.
Join researchers from across the field for 4 days and >100 talks (+ poster sessions)!
Submit abstracts here 👉
icp2026.palaeogenomics.org/abstracts/
Deadline: Nov 30th
Abstract submission is now open for the 1st International Conference on Palaeogenomics!
June 23–26 2026, in Stockholm.
Join researchers from across the field for 4 days and >100 talks (+ poster sessions)!
Submit abstracts here 👉
icp2026.palaeogenomics.org/abstracts/
Deadline: Nov 30th
Reposted by Rosi Fregel
Interested in goats 🐐? Read our pre-print on ancient Irish goats and their connection to the Old Irish goat breed
Just look at this dashing individual, courtesy of the Old Irish Goat society
Just look at this dashing individual, courtesy of the Old Irish Goat society
September 29, 2025 at 8:47 AM
Interested in goats 🐐? Read our pre-print on ancient Irish goats and their connection to the Old Irish goat breed
Just look at this dashing individual, courtesy of the Old Irish Goat society
Just look at this dashing individual, courtesy of the Old Irish Goat society
Reposted by Rosi Fregel
Very happy to see our pre-print on ancient Irish goat genetics on bioRxiv #aDNA #spiergorm
I want to acknowledge this was only possible through the work of the late Dr. Judith Findlater, along with Prof. Eileen Murphy at @qubelfastofficial.bsky.social.
I want to acknowledge this was only possible through the work of the late Dr. Judith Findlater, along with Prof. Eileen Murphy at @qubelfastofficial.bsky.social.
Old Goats: 3,000 years of genetic connectivity of the domestic goat in Ireland
The domestic goat likely first arrived to the island of Ireland as part of the introduction of agriculture approximately 5,900 years ago, and remains a part of the island's biocultural heritage. Howev...
www.biorxiv.org
September 28, 2025 at 9:49 AM
Very happy to see our pre-print on ancient Irish goat genetics on bioRxiv #aDNA #spiergorm
I want to acknowledge this was only possible through the work of the late Dr. Judith Findlater, along with Prof. Eileen Murphy at @qubelfastofficial.bsky.social.
I want to acknowledge this was only possible through the work of the late Dr. Judith Findlater, along with Prof. Eileen Murphy at @qubelfastofficial.bsky.social.
Reposted by Rosi Fregel
Duncan ha recreado todo lo que cargaba Ötzi, el hombre encontrado momificado en los Alpes (video de @pakozoic.bsky.social aquí: www.youtube.com/watch?v=sSlz...) a escala de Playmovil. Creo que este es mi hilo favorito en todo BlueSky.
September 19, 2025 at 2:42 PM
Duncan ha recreado todo lo que cargaba Ötzi, el hombre encontrado momificado en los Alpes (video de @pakozoic.bsky.social aquí: www.youtube.com/watch?v=sSlz...) a escala de Playmovil. Creo que este es mi hilo favorito en todo BlueSky.
Reposted by Rosi Fregel
I have funding for a 2-year dry-lab postdoc to join our team @humanevouu.bsky.social 🧪 (Deadline Oct 21st)
The project will utilize modern and #aDNA data from humans and sheep to study environmental adaptation (including method development and simulations).
Please share!
www.uu.se/en/about-uu/...
The project will utilize modern and #aDNA data from humans and sheep to study environmental adaptation (including method development and simulations).
Please share!
www.uu.se/en/about-uu/...
Postdoctoral position in Population Genomics - Uppsala University
Postdoctoral position in Population Genomics, Department of Organismal Biology, Uppsala University
www.uu.se
September 17, 2025 at 9:15 AM
I have funding for a 2-year dry-lab postdoc to join our team @humanevouu.bsky.social 🧪 (Deadline Oct 21st)
The project will utilize modern and #aDNA data from humans and sheep to study environmental adaptation (including method development and simulations).
Please share!
www.uu.se/en/about-uu/...
The project will utilize modern and #aDNA data from humans and sheep to study environmental adaptation (including method development and simulations).
Please share!
www.uu.se/en/about-uu/...
Reposted by Rosi Fregel
A small thing but this is probably the only point in my career my extended family will half know what I do (thanks to the Meath Chronicle).
September 15, 2025 at 8:08 AM
A small thing but this is probably the only point in my career my extended family will half know what I do (thanks to the Meath Chronicle).
Denisovan mitochondrial DNA from dental calculus of the >146,000-year-old Harbin cranium www.cell.com/cell/fulltex...
Denisovan mitochondrial DNA from dental calculus of the >146,000-year-old Harbin cranium
A mitochondrial genome from Middle Pleistocene hominin dental calculus from northeastern
China clusters with mtDNAs of early Denisovan individuals in Siberia, linking a nearly
complete cranium to Deni...
www.cell.com
September 9, 2025 at 2:17 PM
Denisovan mitochondrial DNA from dental calculus of the >146,000-year-old Harbin cranium www.cell.com/cell/fulltex...
Reposted by Rosi Fregel
🦣🍖🧬 Fully funded 3-yr PhD in palaeogenomics & bioinformatics! Help me push non-model palaeogenomes beyond their limits @DTU in Denmark.
Start: Feb 2026 (flexible)
Application deadline: 24 Oct 2025
For details click here: tinyurl.com/BioExtPhD
Reposts appreciated 😁
Start: Feb 2026 (flexible)
Application deadline: 24 Oct 2025
For details click here: tinyurl.com/BioExtPhD
Reposts appreciated 😁
September 9, 2025 at 7:37 AM
🦣🍖🧬 Fully funded 3-yr PhD in palaeogenomics & bioinformatics! Help me push non-model palaeogenomes beyond their limits @DTU in Denmark.
Start: Feb 2026 (flexible)
Application deadline: 24 Oct 2025
For details click here: tinyurl.com/BioExtPhD
Reposts appreciated 😁
Start: Feb 2026 (flexible)
Application deadline: 24 Oct 2025
For details click here: tinyurl.com/BioExtPhD
Reposts appreciated 😁