Ryan Hernandez
@rdhernand.bsky.social
From busboy/car washer to population geneticist at UCSF, co/Director of the BMI PhD program & UCSF PREP/PROPEL Programs!!!
Reposted by Ryan Hernandez
Reposted by Ryan Hernandez
Can confirm. I am okay and more motivated than ever to speak up.
Nothing scares this administration more. Their power lies in our silence.
Nothing scares this administration more. Their power lies in our silence.
NIH program officer @jenna-m-norton.bsky.social has been placed on admin leave, sources say.
Norton has been outspoken about the Trump administration's dismantling of science, and she signed the Bethesda Declaration.
Bhattacharya has said that "science is dead without free speech".
Norton has been outspoken about the Trump administration's dismantling of science, and she signed the Bethesda Declaration.
Bhattacharya has said that "science is dead without free speech".
November 14, 2025 at 2:37 AM
Can confirm. I am okay and more motivated than ever to speak up.
Nothing scares this administration more. Their power lies in our silence.
Nothing scares this administration more. Their power lies in our silence.
Reposted by Ryan Hernandez
I wish more people would understand that real progress and innovation lies in using everyone’s potential, not just the few…that is where the real strength lies. The question is always, who is really benefiting from the status quo…let’s follow the money, shall we?
Powerful conversation on Next Question with Katie Couric from September: The Real Reason DEI Programs Failed According to Civil Rights Icon Bryan Stevenson. www.youtube.com/watch?app=de....
The Real Reason DEI Programs Failed According to Civil Rights Icon Bryan Stevenson
YouTube video by Katie Couric
www.youtube.com
November 8, 2025 at 8:30 PM
I wish more people would understand that real progress and innovation lies in using everyone’s potential, not just the few…that is where the real strength lies. The question is always, who is really benefiting from the status quo…let’s follow the money, shall we?
Powerful conversation on Next Question with Katie Couric from September: The Real Reason DEI Programs Failed According to Civil Rights Icon Bryan Stevenson. www.youtube.com/watch?app=de....
The Real Reason DEI Programs Failed According to Civil Rights Icon Bryan Stevenson
YouTube video by Katie Couric
www.youtube.com
November 8, 2025 at 7:38 PM
Powerful conversation on Next Question with Katie Couric from September: The Real Reason DEI Programs Failed According to Civil Rights Icon Bryan Stevenson. www.youtube.com/watch?app=de....
Reposted by Ryan Hernandez
How do GWAS and rare variant burden tests rank gene signals?
In new work @nature.com with @hakha.bsky.social, @jkpritch.bsky.social, and our wonderful coauthors we find that the key factors are what we call Specificity, Length, and Luck!
🧬🧪🧵
www.nature.com/articles/s41...
In new work @nature.com with @hakha.bsky.social, @jkpritch.bsky.social, and our wonderful coauthors we find that the key factors are what we call Specificity, Length, and Luck!
🧬🧪🧵
www.nature.com/articles/s41...
Specificity, length and luck drive gene rankings in association studies - Nature
Genetic association tests prioritize candidate genes based on different criteria.
www.nature.com
November 7, 2025 at 12:05 AM
How do GWAS and rare variant burden tests rank gene signals?
In new work @nature.com with @hakha.bsky.social, @jkpritch.bsky.social, and our wonderful coauthors we find that the key factors are what we call Specificity, Length, and Luck!
🧬🧪🧵
www.nature.com/articles/s41...
In new work @nature.com with @hakha.bsky.social, @jkpritch.bsky.social, and our wonderful coauthors we find that the key factors are what we call Specificity, Length, and Luck!
🧬🧪🧵
www.nature.com/articles/s41...
Reposted by Ryan Hernandez
If you've ever rolled your eyes about research claiming that complex traits (from chocolate preference to socioeconomic status) have simple genetic explanations, check out this great paper from @jbenning.bsky.social @jedidiahcarlson.com @oliviarxiv.bsky.social Ruth Shaw @arbelharpak.bsky.social 🧪🧬
Confounding fuels misinterpretation in human genetics | Proceedings of the Royal Society B: Biological Sciences
The scientific literature has seen a resurgence of interest in genetic influences on human behaviour and socioeconomic outcomes. Such studies face the central difficulty of distinguishing possible causal influences, in particular genetic and non-genetic ...
royalsocietypublishing.org
November 5, 2025 at 9:35 PM
If you've ever rolled your eyes about research claiming that complex traits (from chocolate preference to socioeconomic status) have simple genetic explanations, check out this great paper from @jbenning.bsky.social @jedidiahcarlson.com @oliviarxiv.bsky.social Ruth Shaw @arbelharpak.bsky.social 🧪🧬
Reposted by Ryan Hernandez
A devastating set of decisions on the part of UC leadership to withdraw support from our nationally recognized postdoc program that prioritizes research excellence combined with addressing our university public service mission. www.insidehighered.com/news/faculty...
UC to Stop Funding Systemwide Postdoc Program
Established in 1984 to encourage women and minority Ph.D.s to pursue academia, the program has attracted right-wing criticism for prioritizing diverse candidates.
www.insidehighered.com
November 5, 2025 at 6:53 PM
A devastating set of decisions on the part of UC leadership to withdraw support from our nationally recognized postdoc program that prioritizes research excellence combined with addressing our university public service mission. www.insidehighered.com/news/faculty...
Reposted by Ryan Hernandez
The President's Postdoctoral Fellowship Program is one of the most coveted & prestigious positions for UC graduates. It gives a hiring incentive to campuses who hire recipients for a tenure track position. What a DAMN travesty.
This is capitulation to Trump's demand letter & anti-diversity agenda.
This is capitulation to Trump's demand letter & anti-diversity agenda.
A devastating set of decisions on the part of UC leadership to withdraw support from our nationally recognized postdoc program that prioritizes research excellence combined with addressing our university public service mission. www.insidehighered.com/news/faculty...
UC to Stop Funding Systemwide Postdoc Program
Established in 1984 to encourage women and minority Ph.D.s to pursue academia, the program has attracted right-wing criticism for prioritizing diverse candidates.
www.insidehighered.com
November 5, 2025 at 9:07 PM
The President's Postdoctoral Fellowship Program is one of the most coveted & prestigious positions for UC graduates. It gives a hiring incentive to campuses who hire recipients for a tenure track position. What a DAMN travesty.
This is capitulation to Trump's demand letter & anti-diversity agenda.
This is capitulation to Trump's demand letter & anti-diversity agenda.
Reposted by Ryan Hernandez
And we have now progressed from data analysis to policy recommendations.
I told her that we'd calculate the cash value of her candy haul, that I'd ask her to raid her piggy bank and donate 1/3 the candy cash value to a local food bank, and that I'd add on a 5X match.
I told her that we'd calculate the cash value of her candy haul, that I'd ask her to raid her piggy bank and donate 1/3 the candy cash value to a local food bank, and that I'd add on a 5X match.
November 1, 2025 at 3:48 PM
And we have now progressed from data analysis to policy recommendations.
I told her that we'd calculate the cash value of her candy haul, that I'd ask her to raid her piggy bank and donate 1/3 the candy cash value to a local food bank, and that I'd add on a 5X match.
I told her that we'd calculate the cash value of her candy haul, that I'd ask her to raid her piggy bank and donate 1/3 the candy cash value to a local food bank, and that I'd add on a 5X match.
Reposted by Ryan Hernandez
Zara Weinberg passed away earlier this week. She joined my lab earlier this year when her postdoc lab formally closed.
She was a brilliant scientist, supportive mentor, dear friend, avid music fan, rabid believer in public transit, open science champion, and above all just an amazing human.
She was a brilliant scientist, supportive mentor, dear friend, avid music fan, rabid believer in public transit, open science champion, and above all just an amazing human.
October 31, 2025 at 1:18 PM
Zara Weinberg passed away earlier this week. She joined my lab earlier this year when her postdoc lab formally closed.
She was a brilliant scientist, supportive mentor, dear friend, avid music fan, rabid believer in public transit, open science champion, and above all just an amazing human.
She was a brilliant scientist, supportive mentor, dear friend, avid music fan, rabid believer in public transit, open science champion, and above all just an amazing human.
Reposted by Ryan Hernandez
Why PROPEL? Hear directly from our scholars at the 5th Annual PROPEL Symposium!
October 28, 2025 at 5:50 PM
Why PROPEL? Hear directly from our scholars at the 5th Annual PROPEL Symposium!
Reposted by Ryan Hernandez
as facilitating “the growth of a diverse and international community of Python programmers” is written directly into our mission and core to our values, so we withdrew our application.
October 27, 2025 at 2:47 PM
as facilitating “the growth of a diverse and international community of Python programmers” is written directly into our mission and core to our values, so we withdrew our application.
Reposted by Ryan Hernandez
TLDR; The PSF has made the decision to put our community and our shared diversity, equity, and inclusion values ahead of seeking $1.5M in new revenue. Please read and share. pyfound.blogspot.com/2025/10/NSF-...
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🧵
The official home of the Python Programming Language
www.python.org
October 27, 2025 at 2:47 PM
TLDR; The PSF has made the decision to put our community and our shared diversity, equity, and inclusion values ahead of seeking $1.5M in new revenue. Please read and share. pyfound.blogspot.com/2025/10/NSF-...
🧵
🧵
Reposted by Ryan Hernandez
How does life evolve to adapt to modern cities?
Out now in Science, my PhD work with @lindymcbr.bsky.social uncovers the ancient origin of the “London Underground mosquito” – one of the most iconic examples of urban adaptation.
🧵(1/n)
@science.org
www.science.org/doi/10.1126/science.ady4515
Out now in Science, my PhD work with @lindymcbr.bsky.social uncovers the ancient origin of the “London Underground mosquito” – one of the most iconic examples of urban adaptation.
🧵(1/n)
@science.org
www.science.org/doi/10.1126/science.ady4515
Ancient origin of an urban underground mosquito
Understanding how life is adapting to urban environments represents an important challenge in evolutionary biology. In this work, we investigate a widely cited example of urban adaptation, Culex pipie...
www.science.org
October 25, 2025 at 4:46 AM
How does life evolve to adapt to modern cities?
Out now in Science, my PhD work with @lindymcbr.bsky.social uncovers the ancient origin of the “London Underground mosquito” – one of the most iconic examples of urban adaptation.
🧵(1/n)
@science.org
www.science.org/doi/10.1126/science.ady4515
Out now in Science, my PhD work with @lindymcbr.bsky.social uncovers the ancient origin of the “London Underground mosquito” – one of the most iconic examples of urban adaptation.
🧵(1/n)
@science.org
www.science.org/doi/10.1126/science.ady4515
Reposted by Ryan Hernandez
"...researchers who invest time in their students tend to lead more-productive, more-collaborative groups and attract stronger future students than those who do not." "Time spent with the next generation of scientists is an investment."
www.nature.com/articles/d41...
www.nature.com/articles/d41...
What makes PhD students happy? Good supervision
Supervisors who invest in positive mentoring relationships with their PhD candidates also reap the benefits for their own research.
www.nature.com
October 24, 2025 at 10:46 PM
"...researchers who invest time in their students tend to lead more-productive, more-collaborative groups and attract stronger future students than those who do not." "Time spent with the next generation of scientists is an investment."
www.nature.com/articles/d41...
www.nature.com/articles/d41...
🚨PhD opportunity at the intersection of computation & biology! 🖥️🧬🧪
Ready to tackle complex biological problems with cutting-edge tools? The BMI PhD program @UCSF trains future leaders in comp bio, bioinformatics, & data science.
📢 Info session: 11/6 @ 1 PM PT
bmi.ucsf.edu/admissions
Learn more👇
Ready to tackle complex biological problems with cutting-edge tools? The BMI PhD program @UCSF trains future leaders in comp bio, bioinformatics, & data science.
📢 Info session: 11/6 @ 1 PM PT
bmi.ucsf.edu/admissions
Learn more👇
October 24, 2025 at 6:26 PM
🚨PhD opportunity at the intersection of computation & biology! 🖥️🧬🧪
Ready to tackle complex biological problems with cutting-edge tools? The BMI PhD program @UCSF trains future leaders in comp bio, bioinformatics, & data science.
📢 Info session: 11/6 @ 1 PM PT
bmi.ucsf.edu/admissions
Learn more👇
Ready to tackle complex biological problems with cutting-edge tools? The BMI PhD program @UCSF trains future leaders in comp bio, bioinformatics, & data science.
📢 Info session: 11/6 @ 1 PM PT
bmi.ucsf.edu/admissions
Learn more👇
Building community! Finishing undergrad (or just finished) and interested in gaining research experience before applying to PhD programs and also want to be part of a group that cares about you? Join our next matchmaking event!! Jan 30th 9am - 1pm PT propelscholars.org/matchmaking-...
October 22, 2025 at 1:04 AM
Building community! Finishing undergrad (or just finished) and interested in gaining research experience before applying to PhD programs and also want to be part of a group that cares about you? Join our next matchmaking event!! Jan 30th 9am - 1pm PT propelscholars.org/matchmaking-...
Reposted by Ryan Hernandez
Looking for a start in science? National PROPEL will host faculty looking to hire full-time research technicians from 5 institutions on Jan 30th. Meet faculty with similar research interests in a series of 10 min interviews. More info at propelscholars.org/matchmaking-event
October 10, 2025 at 7:35 PM
Looking for a start in science? National PROPEL will host faculty looking to hire full-time research technicians from 5 institutions on Jan 30th. Meet faculty with similar research interests in a series of 10 min interviews. More info at propelscholars.org/matchmaking-event
Reposted by Ryan Hernandez
There are unprecedented challenges for science, calling for bold action and collective effort. Training the next generation of scientific leaders has never been more important. Join us as we grow National PROPEL to answer this call. Learn more: propelscholars.org @propelscholars.bsky.social 🧪🧬🖥️🧵
October 9, 2025 at 5:20 AM
There are unprecedented challenges for science, calling for bold action and collective effort. Training the next generation of scientific leaders has never been more important. Join us as we grow National PROPEL to answer this call. Learn more: propelscholars.org @propelscholars.bsky.social 🧪🧬🖥️🧵
Reposted by Ryan Hernandez
SINGER, our ARG inference method, is finally published and freely available online:
doi.org/10.1038/s415...
It was a long journey – 16 months from initial submission to acceptance. Is it just me, or has peer review gotten more arduous lately? 4+ rounds of review isn't so unusual these days...
doi.org/10.1038/s415...
It was a long journey – 16 months from initial submission to acceptance. Is it just me, or has peer review gotten more arduous lately? 4+ rounds of review isn't so unusual these days...
Robust and accurate Bayesian inference of genome-wide genealogies for hundreds of genomes - Nature Genetics
SINGER is a method for creating ancestral recombination graphs to understand the genealogical history of genomes. The method has increased speed, and thus scalability, without sacrificing accuracy.
doi.org
September 11, 2025 at 3:50 AM
SINGER, our ARG inference method, is finally published and freely available online:
doi.org/10.1038/s415...
It was a long journey – 16 months from initial submission to acceptance. Is it just me, or has peer review gotten more arduous lately? 4+ rounds of review isn't so unusual these days...
doi.org/10.1038/s415...
It was a long journey – 16 months from initial submission to acceptance. Is it just me, or has peer review gotten more arduous lately? 4+ rounds of review isn't so unusual these days...
Reposted by Ryan Hernandez
I want to try something again at #ASHG25 this year: I'll block some time on Thursday and Friday afternoons to meet with trainees who would be interested to chat on any topic.
I did this last year and it was great to meet a whole bunch of new people, at all career stages!
I did this last year and it was great to meet a whole bunch of new people, at all career stages!
October 6, 2025 at 11:14 PM
I want to try something again at #ASHG25 this year: I'll block some time on Thursday and Friday afternoons to meet with trainees who would be interested to chat on any topic.
I did this last year and it was great to meet a whole bunch of new people, at all career stages!
I did this last year and it was great to meet a whole bunch of new people, at all career stages!
Reposted by Ryan Hernandez
Excited to preprint our latest work (w/ Drew DeHaas, Zhibai Jia, Leo Speidel) on using ARGs for demographic inference. w/ applications using data from 1000 Genomes Project. www.biorxiv.org/content/10.1...
Inference of complex demographic history using composite likelihood based on whole-genome genealogies
Accurate parametric inference on complex demographic models is a continuing challenge in population genetics. Ancestral recombination graphs (ARGs) provide richer information than simple population ge...
www.biorxiv.org
October 8, 2025 at 2:48 PM
Excited to preprint our latest work (w/ Drew DeHaas, Zhibai Jia, Leo Speidel) on using ARGs for demographic inference. w/ applications using data from 1000 Genomes Project. www.biorxiv.org/content/10.1...
There are unprecedented challenges for science, calling for bold action and collective effort. Training the next generation of scientific leaders has never been more important. Join us as we grow National PROPEL to answer this call. Learn more: propelscholars.org @propelscholars.bsky.social 🧪🧬🖥️🧵
October 9, 2025 at 5:20 AM
There are unprecedented challenges for science, calling for bold action and collective effort. Training the next generation of scientific leaders has never been more important. Join us as we grow National PROPEL to answer this call. Learn more: propelscholars.org @propelscholars.bsky.social 🧪🧬🖥️🧵
Reposted by Ryan Hernandez
Estimating the rate of quantitative trait evolution in the presence of gene tree discordance by calculating likelihoods across trees https://www.biorxiv.org/content/10.1101/2025.10.06.680724v1
October 7, 2025 at 1:33 AM
Estimating the rate of quantitative trait evolution in the presence of gene tree discordance by calculating likelihoods across trees https://www.biorxiv.org/content/10.1101/2025.10.06.680724v1