Rahul Nair
@rahulnair91.bsky.social
Postdoc-Vanderbilt (USA)||PhD-University of Würzburg (Germany)||JRF-IISc (India)||Biophysics||Biochemistry||EPR||Structural Biology||Membrane Transporters
Reposted by Rahul Nair
Generative Design of High-Affinity Peptides Using BindCraft [new]
De novo designs peptide ligands for proteins. It generated MDM2 binders (nM affinity) and WDR5 binders (sub-µM affinity), with potency improved via stapling.
De novo designs peptide ligands for proteins. It generated MDM2 binders (nM affinity) and WDR5 binders (sub-µM affinity), with potency improved via stapling.
July 26, 2025 at 5:25 AM
Generative Design of High-Affinity Peptides Using BindCraft [new]
De novo designs peptide ligands for proteins. It generated MDM2 binders (nM affinity) and WDR5 binders (sub-µM affinity), with potency improved via stapling.
De novo designs peptide ligands for proteins. It generated MDM2 binders (nM affinity) and WDR5 binders (sub-µM affinity), with potency improved via stapling.
Reposted by Rahul Nair
Now out in Structure: Paper on high-resolution #cryoEM using the 100 kV Tundra cryo-TEM by Dimple Karia, Adrian Koh, @abhaykot.bsky.social, @lingboyu.bsky.social, @landerlab.bsky.social and many others. Happy to have contributed to this effort. Check it out:
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Sub-3 Å resolution protein structure determination by single-particle cryo-EM at 100 keV
Cryoelectron microscopy (cryo-EM) has transformed structural biology by providing high-resolution insights into biological macromolecules. We report s…
www.sciencedirect.com
July 30, 2025 at 9:50 PM
Now out in Structure: Paper on high-resolution #cryoEM using the 100 kV Tundra cryo-TEM by Dimple Karia, Adrian Koh, @abhaykot.bsky.social, @lingboyu.bsky.social, @landerlab.bsky.social and many others. Happy to have contributed to this effort. Check it out:
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...