Pankaj Jadhav
@pvjadhav.bsky.social
Scientist. Anime buff. Postdoctoral fellow at University of Michigan. In situ cryoET. Integrative structural biology.
Reposted by Pankaj Jadhav
Khosrozadeh, @benoitzuber.bsky.social et al. developed CryoVesNet, which enables accurate segmentation of synaptic vesicles in cryo-electron tomograms. rupress.org/jcb/article/...
📕 In Cellular Neurobiology collection: rupress.org/jcb/collecti...
#SfN25
📕 In Cellular Neurobiology collection: rupress.org/jcb/collecti...
#SfN25
November 16, 2025 at 4:15 PM
Khosrozadeh, @benoitzuber.bsky.social et al. developed CryoVesNet, which enables accurate segmentation of synaptic vesicles in cryo-electron tomograms. rupress.org/jcb/article/...
📕 In Cellular Neurobiology collection: rupress.org/jcb/collecti...
#SfN25
📕 In Cellular Neurobiology collection: rupress.org/jcb/collecti...
#SfN25
Reposted by Pankaj Jadhav
Really cool new tech to engineer native gut bacteria inside living animals using mobile CRISPR-associated transposases!
Non-engrafting donor E. coli + broad-host-range conjugation system + guide-RNA–directed targeting
www.science.org/doi/10.1126/...
#microsky #microbiomesky 🧪
Non-engrafting donor E. coli + broad-host-range conjugation system + guide-RNA–directed targeting
www.science.org/doi/10.1126/...
#microsky #microbiomesky 🧪
Metagenomic editing of commensal bacteria in vivo using CRISPR-associated transposases
Although metagenomic sequencing has revealed a rich microbial biodiversity in the mammalian gut, methods to genetically alter specific species in the microbiome are highly limited. Here, we introduce ...
www.science.org
November 14, 2025 at 5:46 AM
Really cool new tech to engineer native gut bacteria inside living animals using mobile CRISPR-associated transposases!
Non-engrafting donor E. coli + broad-host-range conjugation system + guide-RNA–directed targeting
www.science.org/doi/10.1126/...
#microsky #microbiomesky 🧪
Non-engrafting donor E. coli + broad-host-range conjugation system + guide-RNA–directed targeting
www.science.org/doi/10.1126/...
#microsky #microbiomesky 🧪
Reposted by Pankaj Jadhav
MISO: microfluidic protein isolation enables single-particle cryo-EM structure determination from a single cell colony.
Or from a single dish of HEK cell culture in the case of two membrane proteins.
Out in Nature Methods now! lnkd.in/gpyBSceg
Wonderful collaboration with the Efremov lab.
Or from a single dish of HEK cell culture in the case of two membrane proteins.
Out in Nature Methods now! lnkd.in/gpyBSceg
Wonderful collaboration with the Efremov lab.
November 14, 2025 at 6:38 PM
MISO: microfluidic protein isolation enables single-particle cryo-EM structure determination from a single cell colony.
Or from a single dish of HEK cell culture in the case of two membrane proteins.
Out in Nature Methods now! lnkd.in/gpyBSceg
Wonderful collaboration with the Efremov lab.
Or from a single dish of HEK cell culture in the case of two membrane proteins.
Out in Nature Methods now! lnkd.in/gpyBSceg
Wonderful collaboration with the Efremov lab.
Reposted by Pankaj Jadhav
MitoEM 2.0 - A Benchmark for Challenging 3D MitochondriaInstance Segmentation from EM Images https://www.biorxiv.org/content/10.1101/2025.11.12.687478v1
November 14, 2025 at 3:16 AM
MitoEM 2.0 - A Benchmark for Challenging 3D MitochondriaInstance Segmentation from EM Images https://www.biorxiv.org/content/10.1101/2025.11.12.687478v1