Putrino Lab
@putrinolab.bsky.social
#LongCOVID, #MECFS, chronic #lyme scientists and clinicians: This energy! Bring it each day someone tries to force you to follow the status quo, bring it each time someone tries to slow you down just because their insecure ass can't keep up. People are depending on us. Move faster! Show urgency!
November 7, 2025 at 9:28 PM
#LongCOVID, #MECFS, chronic #lyme scientists and clinicians: This energy! Bring it each day someone tries to force you to follow the status quo, bring it each time someone tries to slow you down just because their insecure ass can't keep up. People are depending on us. Move faster! Show urgency!
Hi all, across our six centers serving people with spinal cord injury, stroke, TBI, #LongCOVID, #MECFS, chronic #lyme, new parents, cerebral palsy and many other conditions, roughly 20% are dependent on SNAP benefits for survival. So we're trying to pull together a food drive! 1/
November 7, 2025 at 3:29 PM
Hi all, across our six centers serving people with spinal cord injury, stroke, TBI, #LongCOVID, #MECFS, chronic #lyme, new parents, cerebral palsy and many other conditions, roughly 20% are dependent on SNAP benefits for survival. So we're trying to pull together a food drive! 1/
Delighted to receive this in the mail yesterday and congrats to Giorgia Lupi on getting this out. THANK YOU for taking time to discuss #LongCOVID and the need for accurate, inclusive and honest representation of the people we collect our data from. Amazing work. 🙏🏻
November 4, 2025 at 1:39 PM
Delighted to receive this in the mail yesterday and congrats to Giorgia Lupi on getting this out. THANK YOU for taking time to discuss #LongCOVID and the need for accurate, inclusive and honest representation of the people we collect our data from. Amazing work. 🙏🏻
at least 30 days:
- 85% of users reported improved control of their illness
- 94 said that their understanding of their energy budget was improved
- 90% said that their day-to-day energy management was improved.
- 60% said they had less, and less severe, PEM episodes
Some
5/
- 85% of users reported improved control of their illness
- 94 said that their understanding of their energy budget was improved
- 90% said that their day-to-day energy management was improved.
- 60% said they had less, and less severe, PEM episodes
Some
5/
October 18, 2025 at 1:42 PM
at least 30 days:
- 85% of users reported improved control of their illness
- 94 said that their understanding of their energy budget was improved
- 90% said that their day-to-day energy management was improved.
- 60% said they had less, and less severe, PEM episodes
Some
5/
- 85% of users reported improved control of their illness
- 94 said that their understanding of their energy budget was improved
- 90% said that their day-to-day energy management was improved.
- 60% said they had less, and less severe, PEM episodes
Some
5/
anatomy (versus neighboring brain regions). It is precisely this sort of work that is going to teach us where and when to place implants in recipients who have the potential to benefit. As we wrap up another year of phenomenal talks from day 2 of the @NYBCI conference thanks
4/
4/
October 4, 2025 at 1:00 PM
anatomy (versus neighboring brain regions). It is precisely this sort of work that is going to teach us where and when to place implants in recipients who have the potential to benefit. As we wrap up another year of phenomenal talks from day 2 of the @NYBCI conference thanks
4/
4/
derived from the stentrode (overview below) over more than one year, which gives us faith that this technology can persist in the body and sustain digital independence in the user over long periods, making it a highly feasible technology for locked-in patients needing a
2/
2/
October 4, 2025 at 1:00 PM
derived from the stentrode (overview below) over more than one year, which gives us faith that this technology can persist in the body and sustain digital independence in the user over long periods, making it a highly feasible technology for locked-in patients needing a
2/
2/
Incredible talk here at the #UNGA80 #indoorair call to action from our very own Violet Affleck! Reminding us that #longcovid affects all of us, the #covid19 pandemic is ongoing and we have failed to protect our children. Thank you, Violet, for speaking the truth to this room 🙏🏻
September 24, 2025 at 12:27 PM
Incredible talk here at the #UNGA80 #indoorair call to action from our very own Violet Affleck! Reminding us that #longcovid affects all of us, the #covid19 pandemic is ongoing and we have failed to protect our children. Thank you, Violet, for speaking the truth to this room 🙏🏻
Second, the effects in the IMC-2 + Pax group were highly durable, beyond 600 days post-treatment. This was encouraging that we weren't necessarily looking at a placebo effect or an antiviral protocol that had to be continued in perpetuity. Also of note: these patients were
12/
12/
September 3, 2025 at 12:50 PM
Second, the effects in the IMC-2 + Pax group were highly durable, beyond 600 days post-treatment. This was encouraging that we weren't necessarily looking at a placebo effect or an antiviral protocol that had to be continued in perpetuity. Also of note: these patients were
12/
12/
dysautonomia, and studied the 2 groups across different timepoints: Day 120, Day 305 and Day 731. When we analyzed the data a few interesting things popped out at us. First, IMC-2 + Paxlovid outperforms IMC-2 alone in improving fatigue, dysautonomia and brain fog (p<0.0001).
11/
11/
September 3, 2025 at 12:50 PM
dysautonomia, and studied the 2 groups across different timepoints: Day 120, Day 305 and Day 731. When we analyzed the data a few interesting things popped out at us. First, IMC-2 + Paxlovid outperforms IMC-2 alone in improving fatigue, dysautonomia and brain fog (p<0.0001).
11/
11/
The PGIC asks patients to rate their improvement on a scale of 1 to 7. Dr Pridgen captured these data on 3 prominent symptoms of patients attending his clinic: fatigue, brain fog (although we don't love this term, this is the language that was used at the time) and
10/
10/
September 3, 2025 at 12:50 PM
The PGIC asks patients to rate their improvement on a scale of 1 to 7. Dr Pridgen captured these data on 3 prominent symptoms of patients attending his clinic: fatigue, brain fog (although we don't love this term, this is the language that was used at the time) and
10/
10/
individual patient choice, we had the makings of a natural experiment, where some patients decided they wanted to try IMC-2 alone, whilst others wanted to try IMC-2 + Paxlovid. So we were able to split the data we had access to into two groups. Despite the length of the
7/
7/
September 3, 2025 at 12:50 PM
individual patient choice, we had the makings of a natural experiment, where some patients decided they wanted to try IMC-2 alone, whilst others wanted to try IMC-2 + Paxlovid. So we were able to split the data we had access to into two groups. Despite the length of the
7/
7/
the diversity of the people presenting with these diagnoses. Similarly, as we continued to delve into hormones, we started to understand that sex hormones played a role in both symptom presentation and symptom severity by studying testosterone, progesterone and estradiol
11/
11/
June 27, 2025 at 9:53 PM
the diversity of the people presenting with these diagnoses. Similarly, as we continued to delve into hormones, we started to understand that sex hormones played a role in both symptom presentation and symptom severity by studying testosterone, progesterone and estradiol
11/
11/
For instance, in one of our earliest physiology papers with the brilliant @VirusesImmunity, our teams showed that, in our cohort, low morning cortisol was an important variable in allowing a machine learning algorithm to distinguish between people with #LongCOVID and healthy 8/
June 27, 2025 at 9:53 PM
For instance, in one of our earliest physiology papers with the brilliant @VirusesImmunity, our teams showed that, in our cohort, low morning cortisol was an important variable in allowing a machine learning algorithm to distinguish between people with #LongCOVID and healthy 8/
Excerpt of an email received by a mentee of mine who is currently transitioning to independence as a career researcher. This is happening all over the country right now. The “equity research” my mentee was proposing was centered around novel neurotechnologies that increase the 1/
March 25, 2025 at 2:58 PM
Excerpt of an email received by a mentee of mine who is currently transitioning to independence as a career researcher. This is happening all over the country right now. The “equity research” my mentee was proposing was centered around novel neurotechnologies that increase the 1/
Two steps forward, one step back. For #LongCOVID awareness day today I had the honor of joining thousands of other New Yorkers in a peaceful protest to stand against many of the current administration’s recent damaging and thoughtless policies and executive orders. Let there 1/
March 15, 2025 at 9:56 PM
Two steps forward, one step back. For #LongCOVID awareness day today I had the honor of joining thousands of other New Yorkers in a peaceful protest to stand against many of the current administration’s recent damaging and thoughtless policies and executive orders. Let there 1/
Make sure you’re following @coresinai.bsky.social for clinical trial opportunities and updates here!
January 28, 2025 at 4:00 PM
Make sure you’re following @coresinai.bsky.social for clinical trial opportunities and updates here!
I was asked this question on the other, less pleasant, platform. Basically: what drugs to I recommend for mitochondrial dysfunction. Here is my response (🧵): 1/
December 22, 2024 at 1:40 PM
I was asked this question on the other, less pleasant, platform. Basically: what drugs to I recommend for mitochondrial dysfunction. Here is my response (🧵): 1/
Banger of a #LongCovid paper in pre-print today showing that replicating viral DNA can persist in hamsters at least 80 days after intranasal infection.
The study team were able to isolate and amplify infectious virus in 84% of experimental animals.
www.biorxiv.org/content/10.1...
1/
The study team were able to isolate and amplify infectious virus in 84% of experimental animals.
www.biorxiv.org/content/10.1...
1/
December 18, 2024 at 4:19 PM
Banger of a #LongCovid paper in pre-print today showing that replicating viral DNA can persist in hamsters at least 80 days after intranasal infection.
The study team were able to isolate and amplify infectious virus in 84% of experimental animals.
www.biorxiv.org/content/10.1...
1/
The study team were able to isolate and amplify infectious virus in 84% of experimental animals.
www.biorxiv.org/content/10.1...
1/
We worked with @SamsungUS and @Take2Interact to get hundreds of workbooks and free wifi out to low income kids in NY and NJ who didn’t have devices to engage in remote schooling, and we partnered with the incredible @socialcreaturz to start building out programs to address 8/
November 30, 2024 at 4:31 PM
We worked with @SamsungUS and @Take2Interact to get hundreds of workbooks and free wifi out to low income kids in NY and NJ who didn’t have devices to engage in remote schooling, and we partnered with the incredible @socialcreaturz to start building out programs to address 8/
wrong - this doesn’t mean you stick your head in the sand about lockdown problems: with the help of our friends at @LogitechG, our team coordinated the distribution of hundreds of iPads to hospitals all over NY so that people could say goodbye to critically ill loved ones. 7/
November 30, 2024 at 4:31 PM
wrong - this doesn’t mean you stick your head in the sand about lockdown problems: with the help of our friends at @LogitechG, our team coordinated the distribution of hundreds of iPads to hospitals all over NY so that people could say goodbye to critically ill loved ones. 7/
Filed under “more stuff I should have read she’s ago”, thank you so much, @julierehmeyer for sending me this and for all you do in general for the conversation around #LongCovid, #MECFS, chronic #lyme and all infection- (AND *exposure-*) associated complex chronic illnesses
October 24, 2023 at 1:45 PM
Filed under “more stuff I should have read she’s ago”, thank you so much, @julierehmeyer for sending me this and for all you do in general for the conversation around #LongCovid, #MECFS, chronic #lyme and all infection- (AND *exposure-*) associated complex chronic illnesses