Good question - is PCT worth it? Context of antibiotic stewardship is likely also important. Bayesian analysis also interesting:

ADAPT-SEPSIS: “Care guided by measurement of PCT reduces antibiotic duration safely compared with standard care, but CRP does not. All-cause mortality for CRP was inconclusive.” #ccrdownunder

ADAPT-SEPSIS outcomes #ccrdownunder

ADAPT-SEPSIS intervention #ccrdownunder