Plaschka lab
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plaschkalab.bsky.social
Plaschka lab
@plaschkalab.bsky.social
mRNA & cryo-EM enthusiasts at IMP Vienna. Posts are by lab members.
Huge thanks to Belén Pacheco-Fiallos for wonderful illustrations! This image highlights one of the key steps: how mRNA might export through the nuclear pore complex. (3/3)
November 21, 2025 at 5:37 PM
With @rupertfaraway.bsky.social and @thezenklusen.bsky.social , we discuss the proteins and mechanisms that may control mRNA packaging, organization, and export. (2/3)
November 21, 2025 at 5:37 PM
One more thing! Keep an eye out for discoveries and opportunities from the @hohmannulrich.bsky.social lab! They open their doors in February 2026 at the @imbmainz.bsky.social in Mainz, Germany. Get in touch! (4/4)
November 21, 2025 at 5:02 AM
A big ‘Thank you’ to our collaborators: @juliusbrennecke.bsky.social lab, colleagues at the @impvienna.bsky.social, and the entire Vienna BioCenter. Thank you to our reviewers, editor Florian Ullrich, and funding from Boehringer Ingelheim, the ERC and FWF. (3/4)
November 21, 2025 at 5:02 AM
Building on our recent work on nuclear mRNA-protein complexes (www.nature.com/articles/s41...), we combined molecular & cellular approaches to show how the RNA clampase UAP56 and other proteins orchestrate this process – beautifully detailed in Ulrich’s thread! bsky.app/profile/hohm... (2/4)
mRNA recognition and packaging by the human transcription–export complex - Nature
Cryo-electron microscopy and tomography structures of reconstituted and endogenous human mRNA ribonucleoprotein complexes bound to the transcription–export complex reveal how mRNAs are packaged a...
www.nature.com
November 21, 2025 at 5:02 AM
Building on our recent work on nuclear mRNA-protein complexes (www.nature.com/articles/s41...), we combined molecular & cellular approaches to show how the RNA clampase UAP56 and other proteins orchestrate this process – beautifully detailed in Ulrich’s thread! bsky.app/profile/hohm...
Finally out in @nature.com! We uncovered a mechanistic framework for a general and conserved mRNA nuclear export pathway. www.nature.com/articles/s41.... 1/
November 20, 2025 at 3:53 PM