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plaschkalab.bsky.social
Plaschka lab
@plaschkalab.bsky.social
mRNA & cryo-EM enthusiasts at IMP Vienna. Posts are by lab members.
Huge thanks to Belén Pacheco-Fiallos for wonderful illustrations! This image highlights one of the key steps: how mRNA might export through the nuclear pore complex. (3/3)
November 21, 2025 at 5:37 PM
With @rupertfaraway.bsky.social and @thezenklusen.bsky.social , we discuss the proteins and mechanisms that may control mRNA packaging, organization, and export. (2/3)
November 21, 2025 at 5:37 PM
How does messenger RNA (mRNA) get out of the nucleus to become a protein? Eukaryotic mRNA is packaged, exported, and then translated in the cytoplasm. But how do these steps work? And what are open questions? Check out our new review for our take: www.annualreviews.org/content/jour... (1/3)
November 21, 2025 at 5:37 PM
Messenger RNA is made in the nucleus before it is exported to the cytoplasm for translation. But how are only correctly made mRNAs chosen and remodeled in the nucleus for export?
Our new paper investigates the nuclear events leading to human mRNA export. www.nature.com/articles/s41.... (1/4)
November 21, 2025 at 5:02 AM
Congrats to Dr. @julsportell.bsky.social
on her PhD! Her journey as a joint student (Brennecke/Our Lab) led to key insights into gene silencing. Paper: www.cell.com/molecular-ce.... Journey: www.viennabiocenter.org/about/news/t.... CP.
November 20, 2025 at 3:56 PM