Physiological Reports
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physrep.bsky.social
Physiological Reports
@physrep.bsky.social
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A peer-reviewed, online, Open Access journal publishing across all areas of physiology. A collaboration between The Physiological Society and the American Physiological Society.
Website: https://physoc.onlinelibrary.wiley.com/journal/2051817x
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physrep.bsky.social
Investigation of #masseter #muscle in #microphthalmia mice (with Mitf mutation and masticatory dysfunction) shows increased myocyte #apoptosis and #fibrosis, reduced masseter muscle mass and low expression of #microRNAs needed for #skeletal muscle development
doi.org/10.14814/phy...
November 25, 2025 at 10:15 AM
physrep.bsky.social
#Heart Failure and #Sexdifferences: in a mouse model of non-reperfused #myocardial #infarction, male mice with #fibroblast-specific knockout of #hyaluronan synthase 2 (#Has2), had exacerbated heart failure vs. wildtype mice; a difference not apparent in female mice.
Fibroblast Has2 limits acute heart failure following myocardial infarction in male mice
Changes to the extracellular matrix support acute wound healing following myocardial infarction. Fibroblasts regulate the composition of the extracellular matrix, in part, by secreting hyaluronan.…
doi.org
November 24, 2025 at 10:15 AM
physrep.bsky.social
A novel #acetaminophen analogue, D-112, has limited effects on #survival and compensatory #cardiorespiratory responses following #hemorrhage and extremity #trauma in a rat model, suggesting it may have potential as an #analgesic after hemorrhage.
doi.org
November 21, 2025 at 10:15 AM
physrep.bsky.social
Investigation of effects of #heatadaptation, induced with home-based stationary #cycling while overdressing, in trained females finds that maintenance of heat adaptation further developed #thermal #resistance and potentiated hot #exercise performance.
doi.org/10.14814/phy...
#Physiology
doi.org
November 20, 2025 at 10:15 AM
Reposted by Physiological Reports
physoc.bsky.social
Join us at this year's President's Lecture to hear from Dame Sally Davies, who will present ‘Antimicrobial Resistance: The Challenge of Leadership.’

A critical global health issue from one of the world’s leading voices.

📆 4 December
📍 Royal Society of Medicine
www.physoc.org/events/presi...
President’s Lecture and Awards Ceremony 2025: Celebrating 150 years of physiology
Join us for the most prestigious event in The Society's calendar - our 2025 President’s Lecture and Awards Ceremony.
www.physoc.org
November 12, 2025 at 6:48 PM
physrep.bsky.social
Developmental exposure to the #antidepressant #sertraline is shown to
induce sex-specific #cardiac structural and functional changes in a mouse model of #myocardial #infarction.
doi.org/10.14814/phy...
#Cardiovascular
Sertraline exposure during development may impact post‐myocardial infarction survival in adult mice
The impact of developmental sertraline exposure on post-myocardial infarction (MI) outcomes.
doi.org
November 18, 2025 at 10:15 AM
physrep.bsky.social
#CarbonMonoxide has #antiischemic and #antiinflammatory effects. This study explores the potential of #CORMA1, a molecule that effects controlled CO release, to protect #kidneys from warm #ischemia and #reperfusion injury in rat and swine models.
doi.org/10.14814/phy...
November 17, 2025 at 10:15 AM
physrep.bsky.social
This new Case report presents a case of #melorheostosis, a rare sclerosing #bone #dysplasia for which the #pathophysiology is poorly understood, and discusses its clinical and potential translational significance.
doi.org/10.14814/phy...
#TranslationalPhysiology
Melorheostosis: Clinical, radiological, and histopathological features with a literature review
Melorheostosis is a rare sclerosing bone dysplasia that can clinically and radiologically mimic common bone disorders, particularly in atypical presentations. Its heterogeneous manifestations and…
doi.org
November 14, 2025 at 10:15 AM
physrep.bsky.social
New data on #mitochondria Aminoacyl-#tRNASynthetase, DARS2, reports secretion by #airway #epithelial cells in response to #TNFα, and a role in #paracrine signaling resulting in M1 #macrophage like phenotype in recipient THP1 cells.
doi.org/10.14814/phy...
November 13, 2025 at 10:15 AM
physrep.bsky.social
Deadline approaching!
Call for Papers on “Tissue Fibrosis Through the Life Course and in Transplanted Organs” will close on 31st Dec. 2025!
Including, but not limited to:
Age-related Fibrosis
Organ Fibrosis
Fibrosis in Transplanted Organs
More Info:
physoc.onlinelibrary.wiley.com/hub/journal/...
November 12, 2025 at 10:15 AM
physrep.bsky.social
Study of overnight deep inspiration patterns in #obstructive #sleep #apnea patients with or without #asthma provides insight into the potential role of deep inspirations in mitigating overnight narrowing in lower #airways and asthma–OSA interactions.
doi.org/10.14814/phy...
#Breathing #Respiratory
Overnight deep inspiration patterns in obstructive sleep apnea patients with and without asthma
Asthma and obstructive sleep apnea (OSA) often co-occur, exacerbating respiratory difficulties and altering airway physiology during sleep. Respiratory obstructions in OSA usually terminate with…
doi.org
November 11, 2025 at 10:15 AM
physrep.bsky.social
This systematic review examines evidence for #Sexdifferences in human #skeletal #muscle fiber types and the influences of #age, physical activity or muscle group.
doi.org/10.14814/phy...
MyoBlue #Exercise #Ageing #Physiology
November 10, 2025 at 10:15 AM
Reposted by Physiological Reports
physoc.bsky.social
📢 Launched today, the Global Climate and Health Summit Phase One report!

It sets out the next steps to drive adaptation to protect lives today & the mitigation needed to secure health for generations to come.

Read the full report ⬇️ www.physoc.org/policy/clima...

#ClimateAction #GCHS2025
Global Climate and Health Summit
The 2025 Global Climate and Health Summit placed physiology and partnerships at the heart of climate and health. Read more
www.physoc.org
November 6, 2025 at 3:13 PM
Reposted by Physiological Reports
apsphysiology.bsky.social
Planning for #APS2026? Stay ahead of the game! Check out key dates and deadlines so you don’t miss a thing: https://www.physiology.org/professional-development/meetings-events/american-physiology-summit/dates-and-deadlines?SSO=Y #WeArePhysiology 🧪
📷: istock
Close-up of a calendar page with the 7th day circled by a pencil tip, highlighting the date on a weekday grid.
November 6, 2025 at 5:00 PM
physrep.bsky.social
Read this physiological Case study which examined #energy balance in two recreational, #ultra-endurance #cyclists on plant-based diets during a 30-day cycle ride across Canada.
doi.org/10.14814/phy...
#ExerciseandDiet #Metabolism #Nutrition
doi.org
November 7, 2025 at 10:15 AM
physrep.bsky.social
Study of heart-focused #breathing and attitude breathing techniques on #heartrate variability in young healthy subjects reports improved #HRV parameters and #cardiorespiratory coherence, with significant differences between sexes and individuals with or without #anxiety.
Heart‐focused breathing technique and attitude breathing technique effects on heart rate variability in young healthy subjects
Heart rate variability (HRV) is controlled mainly by the autonomic nervous system (ANS). The aim of our prospective study was to investigate whether respiratory control influences changes in ANS…
doi.org
November 6, 2025 at 10:15 AM
Reposted by Physiological Reports
apsphysiology.bsky.social
What does the air we breathe have to do with your brain? Studies have been finding links between higher concentrations of certain pollutants and the prevalence of #dementia. Read more from The New York Times: https://ow.ly/26s050XmrXV #ISpyPhysiology 🧪
📷: istock
A man and woman stand side by side outdoors with their eyes closed, smiling slightly and taking a deep breath, enjoying the fresh air under a clear blue sky.
November 4, 2025 at 8:00 PM
Reposted by Physiological Reports
physoc.bsky.social
“Clean air, safe environments, & just energy systems are treated as fundamental rights, not privileges” - Shweta Narayan shares her vision for a healthy planet in our latest blog. Find out more about Shweta's work & clean air initiatives. Read the Q&A ➡️ www.physoc.org/blog/clean-a...
#ClimateAction
November 4, 2025 at 12:07 PM
physrep.bsky.social
Study of #heartrate variability in two birth cohorts, in Finland or Norway, indicates altered #autonomic regulation in adults born preterm with very low birth weight, especially women, potentially contributing to higher #bloodpressure.
doi.org/10.14814/phy...
#Birth #Cardiovascular
November 4, 2025 at 10:15 AM
physrep.bsky.social
#TRPC6 channels are implicated in pathogenesis of severe #nephrotic syndromes. This study of TRPC6 in normal physiological #podocyte functions reports roles in #MMP7-shedding of #nephrin ectodomains and #apoptosis.
doi.org/10.14814/phy...
#Renal #IonChannels
November 3, 2025 at 10:15 AM
physrep.bsky.social
Retrospective cohort study on effects of #caffeine in persons starting #Sodium-glucose #cotransporter-2 inhibitors, indicates high caffeine consumption may reduce the early decline in estimated #glomerular #filtration rate with SGLT2i therapy.
doi.org/10.14814/phy...
#Heart #Kidney
October 31, 2025 at 10:15 AM
physrep.bsky.social
This new invited Review discusses how food-related #gut or #endocrine signals and #microbial #metabolites are detected by vagal pathways in #Interoception mediated regulation of #feeding and #glucose #metabolism.

doi.org/10.14814/phy...
October 30, 2025 at 10:15 AM
Reposted by Physiological Reports
physoc.bsky.social
📢 Our Conference Attendance Award closes in one week!

Get support to attend the upcoming #HumanMovement2025. ⏰ The next round of applications closes on 31 October. Apply now ⬇️
Conference Attendance Award
Take advantage of The Physiological Society’s travel grants to help physiologists attend conferences and workshops – an invaluable networking opportunity.
www.physoc.org
October 24, 2025 at 11:07 AM
Reposted by Physiological Reports
apsphysiology.bsky.social
After you've submitted your #APS2026 abstract, what comes next? Applying for awards! Many of them are abstract-based, so kill two birds with one stone:
• Submit abstract by 12/3: https://ow.ly/SZhL50X9qjA
• Apply for awards (deadlines vary): https://ow.ly/NaLn50X9qjy
#ProfDev 🧪
A woman in a vest shakes hands with an award presenter at the American Physiology Summit. Text says "Travel and abstract-based awards now accepting applications, visit website for details and deadlines."
October 16, 2025 at 1:00 PM
physrep.bsky.social
#Nicotinamide #N-methyltransferase inhibition is shown to improve limb function in experimental #peripheral #artery disease in male mice.
doi.org/10.14814/phy...
#Ischemia #SkeletalMuscle
doi.org
October 27, 2025 at 10:15 AM