Øyvind Myrvoll Lorentzen
oeyvindml.bsky.social
Øyvind Myrvoll Lorentzen
@oeyvindml.bsky.social
MD PhD. Interested in infectious diseases, biofilms, bacterial evolution, adaptation and AMR.
Reposted by Øyvind Myrvoll Lorentzen
New paper out in @pnas.org, and it made the cover! 👁️

We represent plasmids as circles and mutations as dots, resembling an eye, because in this paper we literally 𝑤𝑎𝑡𝑐ℎ plasmids evolve.

‼️Check Paula’s 🧵 and the paper👇

𝗣𝗹𝗮𝘀𝗺𝗶𝗱 𝗺𝘂𝘁𝗮𝘁𝗶𝗼𝗻 𝗿𝗮𝘁𝗲𝘀 𝘀𝗰𝗮𝗹𝗲 𝘄𝗶𝘁𝗵 𝗰𝗼𝗽𝘆 𝗻𝘂𝗺𝗯𝗲𝗿
www.pnas.org/doi/10.1073/...
January 27, 2026 at 8:23 PM
Reposted by Øyvind Myrvoll Lorentzen
We’re excited to kick off a new season of the Klebsiella Seminar Series, held on Thursdays in April 🧫🧬!
We have 3 sessions on pathogenesis, pediatric Klebsiella & translational approaches. We will also have an open session.
Registration is mandatory & FREE in this link
forms.gle/LhJu11WQN6Yy...
🔁
January 12, 2026 at 3:19 PM
Last project of my PhD is out as a preprint!
📣 Preprint Alert: How can evolution recruit existing enzymes during bacterial lifestyle changes?

Discover how mutations in a bifunctional enzyme 🔄 alter bacterial c-di-GMP metabolism, decoupling it from external polyamine signaling, and steering cells from a planktonic to a biofilm lifestyle 🦠
Biofilm selection constitutively activates c-di-GMP synthesis by the bifunctional enzyme MbaA
Biofilms, in which microbes are encased within a self-produced matrix, represent the primary mode of microbial life. Yet, our understanding of the molecular mechanisms governing biofilm formation rema...
www.biorxiv.org
February 14, 2025 at 4:07 PM