Nicholas Tolley
ntolley.bsky.social
Nicholas Tolley
@ntolley.bsky.social
Postdoc in comp neuro @BrownU, interested in biophysical modeling, deep learning, and open-source software development
Reposted by Nicholas Tolley
PhD position in computational neuroscience/brain physics to work with us on biophysical modeling of electric and magnetic brain signals at University of Oslo as part of the Marie Curie EU project @neuronanotechdn.bsky.social. Application deadline: December 9th.
www.jobbnorge.no/en/available...
PhD Research Fellow in computational neuroscience/brain physics (290338) | University of Oslo
Job title: PhD Research Fellow in computational neuroscience/brain physics (290338), Employer: University of Oslo, Deadline: Tuesday, December 9, 2025
www.jobbnorge.no
November 24, 2025 at 2:22 PM
Reposted by Nicholas Tolley
📍Excited to share that our paper was selected as a Spotlight at #NeurIPS2025!

arxiv.org/pdf/2410.03972

It started from a question I kept running into:

When do RNNs trained on the same task converge/diverge in their solutions?
🧵⬇️
November 24, 2025 at 4:43 PM
Reposted by Nicholas Tolley
The Jones comp neuro lab is at #SfN25! Come check out our talks and posters to learn about our latest & greatest Science with HNN! All poster presentation times & locations can be found at jonescompneurolab.github.io/textbook/res...
HNN Textbook
jonescompneurolab.github.io
November 14, 2025 at 4:32 PM
Reposted by Nicholas Tolley
Excited to release our new work: Petri Dish Neural Cellular Automata!

pub.sakana.ai/pdnca

We investigate how multi-agent NCAs can develop into artificial life 🦠 exhibiting complex, emergent behaviors like cyclic dynamics, territorial defense, and spontaneous cooperation.
Introducing Petri Dish Neural Cellular Automata (PD-NCA)

pub.sakana.ai/pdnca/

In this work we explore the role of continual adaptation in artificial life, where the cellular automata in our system do not rely on a fixed set of parameters, but rather learn continuously during the simulation itself.
November 5, 2025 at 12:47 AM
Reposted by Nicholas Tolley
No tricks, just brains in 3D 🧠🧟‍♂️

This cleared human brain slice (~10×7×0.3 cm) was imaged at 0.17 µm/pixel on the 3Di HOTLS lightsheet microscope. Sharp, transparent, undead-level perfection (Alpenglow Biosciences).
#3Dtissueimaging #LightSheet #Halloween
November 1, 2025 at 5:05 PM
Reposted by Nicholas Tolley
Today at #PracticalMEEG2025 Nick @willenjoy.bsky.social and I will be conducting a tutorial on how to simulate EEG/MEG data with our toolbox meegsim. If you happen to be around, come to our virtual booth; we will tell scary stories.👻
October 30, 2025 at 10:14 AM
Reposted by Nicholas Tolley
Revised version of our #NeurIPS2025 paper with full code base in Julia & Python now online, see arxiv.org/abs/2505.13192
October 28, 2025 at 6:27 PM
Reposted by Nicholas Tolley
Check out our latest work led by @joeyzhou.bsky.social on alpha oscillatory networks in PLOS Biology!
➡️ journals.plos.org/plosbiology/...
Do ongoing alpha activity fluctuations influence perceptual sensitivity or criterion?
Distinct alpha networks modulate different aspects of perceptual decision-making
Fluctuations in alpha-band neural oscillations influence whether we perceive faint stimuli, but how these oscillations relate to different perceptual processes is not clear. This study shows that alph...
journals.plos.org
October 23, 2025 at 7:27 PM
Reposted by Nicholas Tolley
🚨Postdoc job offer🚨
Are you interested in beta bursts? Want to help drive methods for laminar inference with MEG? Now hiring a postdoc: run head-cast MEG experiments, help build our laMEG toolbox, and collaborate across Lyon–Marseille–Strasbourg. emploi.cnrs.fr/Offres/CDD/U...
Please repost! 🧠📈
Portail Emploi CNRS - Offre d'emploi - Post-doctorate - Beta bursts & laminar MEG (M/F)
emploi.cnrs.fr
September 18, 2025 at 6:58 AM
Reposted by Nicholas Tolley
Is the the neuroimaging community (broadly conceived) submitting to 𝗡𝗲𝘂𝗿𝗼𝗶𝗺𝗮𝗴𝗲 again?????

Not to be publication police but the shift had seemed major 1-2 years ago.
Looking at the editorial board it seems to have serious scientists once more.
Curious about thoughts of the community.
October 21, 2025 at 4:16 PM
Reposted by Nicholas Tolley
𝗘𝗻𝗱 𝗼𝗳 𝘁𝗵𝗲 𝗲𝗺𝗽𝗶𝗿𝗲 𝗼𝗳 𝗻𝗲𝘂𝗿𝗼𝗻𝘀 𝗶𝗻 𝘁𝗵𝗲 𝗯𝗿𝗮𝗶𝗻??
Astrocytes in the regulation of fear memories!
www.nature.com/articles/s41...
#neuroskyence
h/t @claeneuro.bsky.social
The astrocytic ensemble acts as a multiday trace to stabilize memory - Nature
Emotional experience evokes signalling in astrocytes, which form an ensemble that is reinforced by secondary astrocytic state changes resulting from repeated experience, leading to memory stabilizatio...
www.nature.com
October 21, 2025 at 5:57 PM
Reposted by Nicholas Tolley
Can AI simulations of human research participants advance cognitive science? In @cp-trendscognsci.bsky.social, @lmesseri.bsky.social & I analyze this vision. We show how “AI Surrogates” entrench practices that limit the generalizability of cognitive science while aspiring to do the opposite. 1/
AI Surrogates and illusions of generalizability in cognitive science
Recent advances in artificial intelligence (AI) have generated enthusiasm for using AI simulations of human research participants to generate new know…
www.sciencedirect.com
October 21, 2025 at 8:24 PM
Reposted by Nicholas Tolley
Thrilled to share our new preprint highlighting distinct neurocomputational mechanisms underlying how reward and punishment determine adaptive cognitive control - a massive fMRI study and collaborative team effort with the @shenhavlab.bsky.social 🧠

Link here:
www.biorxiv.org/content/10.1...
Neurocomputational mechanisms underlying the distinct motivational influences of reward and punishment on cognitive control
Human motivation is fundamentally shaped by one's expectations of the reward they could earn for good performance or the punishment they would avoid for poor performance. However, the extent to which ...
www.biorxiv.org
October 20, 2025 at 6:42 PM
Reposted by Nicholas Tolley
Map of spiking activity underlying change detection in the mouse visual system https://www.biorxiv.org/content/10.1101/2025.10.17.683190v1
October 20, 2025 at 12:15 AM
Definitely looking forward to helping run this workshop!
October 17, 2025 at 4:39 PM
Reposted by Nicholas Tolley
📜🎉 I'm happy to share that my review of clinical research investigating aperiodic neural activity is now published!

It examines 177 reports of aperiodic activity in clinical disorders summarizing findings, discussion topics, & making some recommendations!

onlinelibrary.wiley.com/doi/10.1111/...
A Systematic Review of Aperiodic Neural Activity in Clinical Investigations
This systematic literature review examines aperiodic neural activity in clinical disorders, summarizing current findings and discussion topics. One-hundred seventy-seven reports from across 38 distin...
onlinelibrary.wiley.com
October 13, 2025 at 3:12 PM
Reposted by Nicholas Tolley
A glimpse at what #NeuroAI brain models might enable: a topographic vision model predicts stimulation patterns that steer complex object recognition behavior in primates. This could be a key 'software' component for visual prosthetic hardware 🧠🤖🧪
October 8, 2025 at 11:11 AM
Reposted by Nicholas Tolley
Rapidly Reconfigurable Dynamic Computing in Neural Networks with Fixed Synaptic Connectivity https://www.biorxiv.org/content/10.1101/2025.10.05.680523v1
October 6, 2025 at 11:15 PM
Reposted by Nicholas Tolley
Multi-stable oscillations in cortical networks with two classes of inhibition https://www.biorxiv.org/content/10.1101/2025.10.03.680414v1
October 5, 2025 at 8:15 AM
Really great article! I spent a lot of my PhD helping turn the HNN model into an open source python package

We can boast that it’s super quick to install, definitely worth playing around with the GUI or python code if you’re interested in simulating EEG signals with biophysical neurons 🧠 🌊
September 30, 2025 at 9:02 PM
Reposted by Nicholas Tolley
If you’re a @cogneuronews.bsky.social member, check out and vote on the great lineup of symposia for 2026, and plz consider our symposium “Non-invasive meso-scale dynamics of perception and cognition”, organized by @adykstra.bsky.social including James Bonauito and @lonikefaes.bsky.social!
September 29, 2025 at 3:32 PM
Thanks for organizing this awesome workshop @rdgao.bsky.social!
Manuel Brenner and I managed to organize this workshop not knowing we were gonna end up being new neighbors this month. The lineup speaks for itself.

There were some last minute cancellations so we jumped in to fill their big shoes and will talk about the future directions of the new labs too!
September 30, 2025 at 6:08 AM
Reposted by Nicholas Tolley
Our PhD student @ntolley.bsky.social successfully defended his thesis, "Bridging biophysics and emergent dynamics through deep learning assisted modeling of the neocortex", on July 9th, 2025.

Congratulations Dr. Tolley!!! 🎉🎉
August 7, 2025 at 8:23 PM
Reposted by Nicholas Tolley
Postdoc job alert! I’m looking for someone with a PhD in neuroscience/psychology, psychiatry, biomed engineering, computational modeling or a related field to join my NIH-funded team at UCLA studying the neural & computational mechanisms of #interoception in anorexia nervosa 1/2
August 7, 2025 at 4:25 PM