Lightnews — Scholar-powered news

Simone Papa @simonepapa.bsky.social · 4d

Growth hack no one talks about:
💡 Work with people smarter than you.
Insecure minds compete, growth-minded people collaborat.
Every convo = a masterclass, every project = a level up.
Surround yourself with brilliance. 🚀
(by Salman Hashmi)
#Growth #Leadership #Mindset

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Simone Papa @simonepapa.bsky.social · 4d

A “brain-on-a-chip” reveals how inflammation breaks the brain’s barriers, and how tiny repair cells may help rebuild them. This breakthrough could revolutionize treatment for brain injury, sepsis, and neurodegeneration.

neurosciencenews.com/inflammation...

Human Brain-on-a-Chip Reveals How Inflammation Breaks the Mind - Neuroscience News

Researchers have developed brain-on-a-chip technology that uses human tissue to model how the brain’s protective barrier breaks down during inflammation and disease.

neurosciencenews.com

Simone Papa @simonepapa.bsky.social · 5d

🧠 The October issue of #ScienceImmunology!
(by Science Magazine)
This month’s cover features a Review on brain tumor development and the factors shaping the immunosuppressive tumor microenvironment.
www.science.org/toc/sciimmun...

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Simone Papa @simonepapa.bsky.social · 5d

🧠✨ #Fluorescence!
See Myelin Basic Protein (MBP) in a whole mouse brain, key to understanding myelin’s role in nerve signaling and diseases like MS.

Learn more about tissue clearing & 3D imaging
www.translucencebio.com/our-science

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Simone Papa @simonepapa.bsky.social · 8d

🧠 Join us on Oct 24, 3:30 PM (Aula Picone, Sapienza) for brAIns 2025, exploring the link between AI & the Brain!
Talks by Emanuele Rodolà, Francesco Pappone & Bianca Silva + Student Talks & Poster Session 🎙️
🔗 Info & signup: linktr.ee/brainsjuicec...
#brAIns2025 #AI #Neuroscience

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Simone Papa @simonepapa.bsky.social · 11d

🦐 Parhyale hawaiensis for #3DSunday!

A rising crustacean model for evo-devo, regeneration & limb development. microCT imaging reveals its intricate 3D body plan segment by segment, limb by limb.
A powerful system beyond insects! 🔬🏛️ (by Brandy Freitas)
#3DImaging #EvoDevo #MarineBiology

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Simone Papa @simonepapa.bsky.social · 11d

✨ #FluorescenceFriday meets 3D Spatial Biology! Using computational H&E on our 3Di platform, we map NSCLC biopsies from tissue to subcellular scale, revealing hidden TLS 200 µm deep(by Alpenglow Biosciences)

🚀 3D imaging = unbiased counts + richer immune insights.
#SpatialBiology #3DImaging

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Simone Papa @simonepapa.bsky.social · 11d

👁️ New research from the Rompani & Asari labs @embl.org Rome challenges old views of the pupil.

Beyond reacting to light or emotion, it may actively shape vision, integrating input from both eyes and modulating the visual pathway. #Neuroscience #Vision #EMBL

www.embl.org/news/science...

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Simone Papa @simonepapa.bsky.social · 12d

Asked my favorite marker for Tau pathology? 😉 I say at least 10! From early oligomers to late fibrillary tangles, each tells a story (by Danielle Beckman)

In this recent study with CNPRC & Takeda, they mapped Tau progression in monkeys, markers also fit human and mouse tissue
#Neuroscience #Tau

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Simone Papa @simonepapa.bsky.social · 12d

Scientists have designed an interleukin-21 mimic with increased stability and capacity to induce more potent antitumor activity than the native protein, which could inform improved immunotherapies.

www.science.org/doi/10.1126/...

Design of a potent interleukin-21 mimic for cancer immunotherapy

A de novo IL-21 mimic, 21h10, exhibits improved stability and potent antitumor activity in vivo compared with native IL-21.

www.science.org

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Simone Papa @simonepapa.bsky.social · 12d

Creative Minds, Younger Brains: Engaging in music, dance, painting or even (some) gaming is linked to delayed brain aging.
www.nature.com/articles/s41...

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Simone Papa @simonepapa.bsky.social · 13d

🌻 The thymeleaf speedwell (Veronica serpyllifolia) self-pollinates: no bees, no wind, just pollen transfer within one bloom. 🌿

A survival backup in harsh spots, ensuring seeds, though at the cost of diversity. (By Nicolas Hubacz)

#Botany #Nature #Resilience

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Simone Papa @simonepapa.bsky.social · 13d

Jane Goodall, known for her pioneering work with chimpanzees, has passed away aged 91
#JaneGoodall #science
www.nature.com/articles/d41...

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Simone Papa @simonepapa.bsky.social · 13d

Here's a reminder on hashtag #InternationalCoffeeDay: It's OK to take a (coffee) break. ☕

"It’s ... helpful to have a venue to share the day-to-day ups and downs of life as a grad student," a hashtag
#PhD student wrote in this 2019 Working Life.

www.science.org/doi/10.1126/...

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Simone Papa @simonepapa.bsky.social · 16d

🧠✨ Dive into mouse brain connections!

Reconstructed neurons from the thalamus project across the cortex, revealed by fluorescent labeling and advanced ExA-SPIM microscope (by Allen Institute)

#brain #connections

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Simone Papa @simonepapa.bsky.social · 16d

🦠 Inside mouse brain tumor cells: actin (💜) shapes movement mitochondria (💚) fuel survival.

Visualizing both reveals how structure & energy intertwine, keys to tackling aggressive brain cancers.
(by Nicolas Hubacz)
Credit to Dr. Eric Vitriol and Nikon Small World in Motion!

#tumorcells #brain

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Simone Papa @simonepapa.bsky.social · 16d

Last week I joined the “Is AI intelligence?” conference at Sapienza University of Rome with BrainJuiceClub, leading a workshop on dialogue between Neuroscience and AI.

Now we look ahead: BrAIns 2025 on Oct 24, with keynotes, posters & short talks. Join us to share ideas and perspectives! 🧠
#BrAIns

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Simone Papa @simonepapa.bsky.social · 22d

Thank you for sharing this perspective. The Dupret (2013) study is indeed a seminal reference, elegantly bridging circuit mechanisms with our own experience of flexible mental maps. It’s fascinating to see how more recent work, like Valero et al., continues to refine and expand that narrative.

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Simone Papa @simonepapa.bsky.social · 22d

Phosphorylation of the protein Tau is an hallmark of AD, and here it is in our organoid model.
Neurons are labeled in red, phospho-Tau in green (making the overlap yellow) (dr. Joao Pereira - University of Alabama at Birmingham)

Wonderful work by PhD student Maggie Ireland!
#neuroscience #Tau

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Simone Papa @simonepapa.bsky.social · 22d

Inhibitory interneurons may help encode the brain’s internal representation of space.

www.science.org/doi/10.1126/...

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Simone Papa @simonepapa.bsky.social · 22d

Excited to join the first Brainstorming Juice after summer break! 🧠🍹
📍 Tomo, Via degli Etruschi 4
🕕 Thu, Sept 25 – 18:00
Topic: Neuroscience & AI. Come share ideas, projects & feedback! ✨

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Reposted by Simone Papa

Allen Institute @alleninstitute.org · 28d

Open science is not just for researchers. Artist @kindracrick.com created these beautiful neuron portraits with inspiration from Ramón y Cajal's drawings and reference images from our Cell Types Database.

#OpenScienceWeek

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Simone Papa @simonepapa.bsky.social · 24d

Physics laureate Giorgio Parisi speaks about the importance of self-confidence and believing in yourself.

Parisi was awarded the 2021 physics prize for discovering hidden patterns in disordered complex materials.
(By TheNobelPrize)
www.nobelprize.org/prizes/physi...

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Simone Papa @simonepapa.bsky.social · 24d

NEW TOOLKIT release from EBRAINS researchers!

The Virtual Brain Inference #VBI #toolkit has been launched: an open-source software available on the EBRAINS platform.

VBI matches #virtualbrain models with real neuroimaging data (EEG, MEG, fMRI)

www.ebrains.eu/news-and-eve...

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Simone Papa @simonepapa.bsky.social · 24d

I’m happy to share that I’ll be speaking at the workshop A Shared Language for Intelligence: Why Communication Between Neuroscience and AI Is Key.

Looking forward to contributing to the discussion and to connecting with fellow researchers and professionals. Don’t miss it on September 26th!"
#neuro

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