Nishit Srivastava
@nsrivast24.bsky.social
Understanding how cells grow while maintaining intracellular density and crowding, nuclear and cell mechanics. Previously@institutcurie. Alumni
@HFSP@Cambridge_Uni@JNCASR
@HFSP@Cambridge_Uni@JNCASR
Reposted by Nishit Srivastava
A Dual Homeostatic Regulation of Dry Mass and Volume Defines a Target Density in Proliferating Mammalian Cells https://www.biorxiv.org/content/10.1101/2025.04.24.650395v1
April 25, 2025 at 1:30 PM
A Dual Homeostatic Regulation of Dry Mass and Volume Defines a Target Density in Proliferating Mammalian Cells https://www.biorxiv.org/content/10.1101/2025.04.24.650395v1
Reposted by Nishit Srivastava
Just out on bioRxiv - spcg collab with Piel lab: growing mammalian cells use two independent systems — one controlling volume, one driving protein synthesis — to control macromolecular density.
Together, they restore dry mass density homeostasis.
www.biorxiv.org/content/10.1...
Together, they restore dry mass density homeostasis.
www.biorxiv.org/content/10.1...
April 25, 2025 at 3:10 PM
Just out on bioRxiv - spcg collab with Piel lab: growing mammalian cells use two independent systems — one controlling volume, one driving protein synthesis — to control macromolecular density.
Together, they restore dry mass density homeostasis.
www.biorxiv.org/content/10.1...
Together, they restore dry mass density homeostasis.
www.biorxiv.org/content/10.1...
Reposted by Nishit Srivastava
Want to compress cells? Want to know how to do it, which mechanism could sense compression or wondering why should you compress cells? Checkout our review to know more about that!!
In their Review, Laura Faure, Valeria Venturini @valeriaventurini.bsky.social and Pere Roca-Cusachs discuss the biological contexts of cell mechanical compression, the associated mechanisms and the experimental systems engineered to compress cells in vitro.
journals.biologists.com/jcs/article/...
journals.biologists.com/jcs/article/...
March 28, 2025 at 2:10 PM
Want to compress cells? Want to know how to do it, which mechanism could sense compression or wondering why should you compress cells? Checkout our review to know more about that!!
Reposted by Nishit Srivastava
🚨 Paper Alert 🚨
Absolutely delighted to share our last paper on "spatial mechano-transcriptomics" @naturemethods👇!!
www.nature.com/articles/s41...
Absolutely delighted to share our last paper on "spatial mechano-transcriptomics" @naturemethods👇!!
www.nature.com/articles/s41...
A computational pipeline for spatial mechano-transcriptomics - Nature Methods
The authors present a computational framework that leverages mechanical force inference and spatial transcriptomics to enable analyses of the interplay between the transcriptomic and mechanical state.
www.nature.com
March 17, 2025 at 12:53 PM
🚨 Paper Alert 🚨
Absolutely delighted to share our last paper on "spatial mechano-transcriptomics" @naturemethods👇!!
www.nature.com/articles/s41...
Absolutely delighted to share our last paper on "spatial mechano-transcriptomics" @naturemethods👇!!
www.nature.com/articles/s41...
