A 6-month-old baby boy was referred to a pediatric neurology clinic in Brazil for evaluation of developmental delay. At the beginning of the second trimester, the baby’s mother had had a rash. At birth, the baby had microcephaly. 1/2

#MedSky #PedSky #NeuroSky

Take a look back at the numbers that went into a year of publishing at the world’s leading medical journal.

To discover the 15 articles NEJM editors selected as among the most impactful in advancing clinical practice and patient care this year, download the Notable Articles of 2025: nej.md/3YD0EXU

In a Review Article on measles, Lien Anh Ha Do, MD, PhD, and Kim Mulholland, MB, BS, MD, review the epidemiology, clinical presentation, and associated illnesses as well as treatment and prevention strategies. Read the full review: nej.md/4lmC1Ir

#MedSky #PedSky #IDSky

Our latest video in our partnership with @glaucomflecken.bsky.social summarizes the final analysis of 23 years of follow-up to evaluate the long-term effects of PSA screening. Read the full analysis for free: nej.md/DrG32

#MedSky #ProstateCancer #MedEd

NEJM Clinician Editor-in-Chief Raja-Elie Abdulnour, MD, talks about a new study on using cap-refill time to manage resuscitation in septic shock. Read the full summary and see what else is new in this week's edition: nej.md/4s9tDQS

#CriticalCare

Among adults 65 years of age or older, a high-dose influenza vaccine did not result in a significantly lower incidence of hospitalization for influenza or pneumonia than a standard-dose vaccine. Full DANFLU-2 trial results and Research Summary: nej.md/4lPGMtT

#MedSky #IDSky

A 72-year-old woman presented to the dermatology clinic with a 3.5-month history of an enlarging, painless lump on her left cheek. 1/2

#MedSky #DermSky