Nick DeVito
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ndevitomd.bsky.social
Nick DeVito
@ndevitomd.bsky.social
720 followers 960 following 220 posts
Assistant Prof, GI Oncologist @
Duke Cancer researching immunotherapy, metastasis, and the immune microenvironment.

#FirstGen. USouthFlorida alumnus. Tufts residency survivor.

Patients don’t fail treatments, treatments fail patients.

Opinions=mine
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ndevitomd.bsky.social
Neat. More evidence for the role of TLR4 in metastasis.

pubmed.ncbi.nlm.nih.gov/36417489/
Tumor-intrinsic NLRP3-HSP70-TLR4 axis drives premetastatic niche development and hyperprogression during anti-PD-1 immunotherapy - PubMed
The tumor-intrinsic NOD-, LRR- and pyrin domain-containing protein-3 (NLRP3) inflammasome-heat shock protein 70 (HSP70) signaling axis is triggered by CD8<sup>+</sup> T cell cytotoxicity and contributes to the development of adaptive resistance to anti-programmed cell death protein 1 (PD-1) immunoth …
pubmed.ncbi.nlm.nih.gov
November 15, 2025 at 7:19 PM
ndevitomd.bsky.social
Yes definitely and we have a spectral sorter here now, so more users soon.

I will contact flowjo w/our core!
October 29, 2025 at 4:00 PM
ndevitomd.bsky.social
Thanks again for posting this - have you reached out to FlowJo about adding it as an R plugin?
October 29, 2025 at 2:46 PM