NC3Rs
@nc3rs.bsky.social
A UK-based scientific organisation dedicated to helping the research community worldwide to identify, develop and use 3Rs technologies and approaches. https://nc3rs.org.uk/
At the @lasa-uk.bsky.social conference this week Jess Eddy shared NC3Rs resources on evaluating environmental enrichment: nc3rs.org.uk/3rs-resource...
Other talks in a great 3Rs session covered best practice in oncology, positive welfare science, zebrafish enrichment and rodent housing refinements.
Other talks in a great 3Rs session covered best practice in oncology, positive welfare science, zebrafish enrichment and rodent housing refinements.
November 20, 2025 at 3:30 PM
At the @lasa-uk.bsky.social conference this week Jess Eddy shared NC3Rs resources on evaluating environmental enrichment: nc3rs.org.uk/3rs-resource...
Other talks in a great 3Rs session covered best practice in oncology, positive welfare science, zebrafish enrichment and rodent housing refinements.
Other talks in a great 3Rs session covered best practice in oncology, positive welfare science, zebrafish enrichment and rodent housing refinements.
Congratulations to @alessiovagnoni.bsky.social who has been announced as a recipient of this year’s AAALAC International Global 3Rs Award recognising his ongoing work in advancing the 3Rs: www.aaalac.org/awards/globa...
Global 3Rs Winners
LEARN MORE / APPLY 2025 Award Winners ASIA-PACIFIC Bing Zhou, Ph.D., M.D. “Amelioration of nonalcoholic fatty liver disease by inhibiting the deubiquitylating enzyme RPN11” Cell Metabolism Sha
www.aaalac.org
November 14, 2025 at 12:40 PM
Congratulations to @alessiovagnoni.bsky.social who has been announced as a recipient of this year’s AAALAC International Global 3Rs Award recognising his ongoing work in advancing the 3Rs: www.aaalac.org/awards/globa...
The latest issue of Tech3Rs, our newsletter for animal technicians, has been published: nc3rs.org.uk/3rs-resource...
November 12, 2025 at 3:21 PM
The latest issue of Tech3Rs, our newsletter for animal technicians, has been published: nc3rs.org.uk/3rs-resource...
The NC3Rs has a strong track record in investing in in vitro models of human disease that replace the use of animals. We have recently partnered with the MRC, Wellcome and Innovate UK on a £15.9M funding call to develop human in vitro models of complex disease.
nc3rs.org.uk/news/nc3rs-g...
nc3rs.org.uk/news/nc3rs-g...
NC3Rs grant holders receive funding in MRC call
£15.9M awarded to develop human in vitro models of complex disease.
nc3rs.org.uk
November 12, 2025 at 10:37 AM
The NC3Rs has a strong track record in investing in in vitro models of human disease that replace the use of animals. We have recently partnered with the MRC, Wellcome and Innovate UK on a £15.9M funding call to develop human in vitro models of complex disease.
nc3rs.org.uk/news/nc3rs-g...
nc3rs.org.uk/news/nc3rs-g...
Today the UK government has released a strategy to support the development, validation and uptake of alternative methods.
Read more: www.gov.uk/government/n...
Read more: www.gov.uk/government/n...
Animal testing to be phased out faster as UK unveils roadmap for alternative methods
New plan backs researchers to seize on new and developing opportunities to phase out animal tests with specific commitments for the coming years.
www.gov.uk
November 11, 2025 at 9:26 AM
Today the UK government has released a strategy to support the development, validation and uptake of alternative methods.
Read more: www.gov.uk/government/n...
Read more: www.gov.uk/government/n...
❗Survey deadline extended: Friday 12 December❗
If you have experience of the monocyte activation test as a replacement for the rabbit pyrogen test, please take 30 minutes to share your insights: nc3rs.org.uk/our-portfoli...
If you have experience of the monocyte activation test as a replacement for the rabbit pyrogen test, please take 30 minutes to share your insights: nc3rs.org.uk/our-portfoli...
NEW SURVEY. Do you manufacture, regulate or produce biological therapeutics? Help the NC3Rs shape the future of non-animal pyrogenicity testing of biologics: nc3rs.org.uk/our-portfoli...
Supporting 3Rs approaches in biologicals testing
nc3rs.org.uk
November 10, 2025 at 12:54 PM
❗Survey deadline extended: Friday 12 December❗
If you have experience of the monocyte activation test as a replacement for the rabbit pyrogen test, please take 30 minutes to share your insights: nc3rs.org.uk/our-portfoli...
If you have experience of the monocyte activation test as a replacement for the rabbit pyrogen test, please take 30 minutes to share your insights: nc3rs.org.uk/our-portfoli...
Our next welfare webinar will focus on using positive reinforcement techniques to improve the welfare of pigs and dogs in research by encouraging voluntary cooperation with procedures and reducing stress.
📅 Thursday 27 November, 12.30 – 13.30 (GMT)
👉 Register: nc3rs.org.uk/events/welfa...
📅 Thursday 27 November, 12.30 – 13.30 (GMT)
👉 Register: nc3rs.org.uk/events/welfa...
November 6, 2025 at 3:02 PM
Our next welfare webinar will focus on using positive reinforcement techniques to improve the welfare of pigs and dogs in research by encouraging voluntary cooperation with procedures and reducing stress.
📅 Thursday 27 November, 12.30 – 13.30 (GMT)
👉 Register: nc3rs.org.uk/events/welfa...
📅 Thursday 27 November, 12.30 – 13.30 (GMT)
👉 Register: nc3rs.org.uk/events/welfa...
New publication: Home-cage monitoring to refine and reduce animal use in drug safety testing
A cross-sector collaboration demonstrates that non-invasive, continuous monitoring of rodent behaviour improves detection of central nervous system side effects for new drugs.
👉 nc3rs.org.uk/news/home-ca...
A cross-sector collaboration demonstrates that non-invasive, continuous monitoring of rodent behaviour improves detection of central nervous system side effects for new drugs.
👉 nc3rs.org.uk/news/home-ca...
November 5, 2025 at 9:33 AM
New publication: Home-cage monitoring to refine and reduce animal use in drug safety testing
A cross-sector collaboration demonstrates that non-invasive, continuous monitoring of rodent behaviour improves detection of central nervous system side effects for new drugs.
👉 nc3rs.org.uk/news/home-ca...
A cross-sector collaboration demonstrates that non-invasive, continuous monitoring of rodent behaviour improves detection of central nervous system side effects for new drugs.
👉 nc3rs.org.uk/news/home-ca...
⏳ Pyrogenicity testing survey closing on Thursday 7 November.
Please take 30 minutes to share your insights into the monocyte activation test and support our work to drive wider adoption of non-animal approaches in biologics quality control testing.
Take the survey: nc3rs.org.uk/our-portfoli...
Please take 30 minutes to share your insights into the monocyte activation test and support our work to drive wider adoption of non-animal approaches in biologics quality control testing.
Take the survey: nc3rs.org.uk/our-portfoli...
NEW SURVEY. Do you manufacture, regulate or produce biological therapeutics? Help the NC3Rs shape the future of non-animal pyrogenicity testing of biologics: nc3rs.org.uk/our-portfoli...
Supporting 3Rs approaches in biologicals testing
nc3rs.org.uk
November 3, 2025 at 3:13 PM
⏳ Pyrogenicity testing survey closing on Thursday 7 November.
Please take 30 minutes to share your insights into the monocyte activation test and support our work to drive wider adoption of non-animal approaches in biologics quality control testing.
Take the survey: nc3rs.org.uk/our-portfoli...
Please take 30 minutes to share your insights into the monocyte activation test and support our work to drive wider adoption of non-animal approaches in biologics quality control testing.
Take the survey: nc3rs.org.uk/our-portfoli...
@inserm.fr have reached approaching 1,000 researchers with a training course that uses the NC3Rs Experimental Design Assistant (EDA) to teach best practice for experimental design of in vivo studies.
Learn more in our interview with the organiser behind Parcours-EDA: nc3rs.org.uk/news/experim...
Learn more in our interview with the organiser behind Parcours-EDA: nc3rs.org.uk/news/experim...
The Experimental Design Assistant: From research planning to training tool
A national training initiative in France is using the EDA to embed robust experimental design into real-world research practice.
nc3rs.org.uk
October 31, 2025 at 10:51 AM
@inserm.fr have reached approaching 1,000 researchers with a training course that uses the NC3Rs Experimental Design Assistant (EDA) to teach best practice for experimental design of in vivo studies.
Learn more in our interview with the organiser behind Parcours-EDA: nc3rs.org.uk/news/experim...
Learn more in our interview with the organiser behind Parcours-EDA: nc3rs.org.uk/news/experim...
Our Chief Executive Vicky Robinson provided comment on the statistics of scientific procedures on animals carried out in Great Britain in 2024, released today.
Read the report from the Home Office: www.gov.uk/government/s...
Read the report from the Home Office: www.gov.uk/government/s...
October 23, 2025 at 11:34 AM
Our Chief Executive Vicky Robinson provided comment on the statistics of scientific procedures on animals carried out in Great Britain in 2024, released today.
Read the report from the Home Office: www.gov.uk/government/s...
Read the report from the Home Office: www.gov.uk/government/s...
NC3Rs staff have co-authored a new chapter in the fourth edition of the IACUC Handbook to support ethical review bodies assess the reliability of animal research. It includes practical support to avoid animals being wasted in studies that produce unreliable results: nc3rs.org.uk/news/conside...
October 22, 2025 at 12:58 PM
NC3Rs staff have co-authored a new chapter in the fourth edition of the IACUC Handbook to support ethical review bodies assess the reliability of animal research. It includes practical support to avoid animals being wasted in studies that produce unreliable results: nc3rs.org.uk/news/conside...
⏳ NC3Rs-BBSRC Business Interaction Vouchers application deadline approaching: 16.00, Tuesday 4 November.
Apply for up to £25k to support industry-academic collaborations that advance 3Rs approaches in oncology, cardiovascular science and new approach methodologies: nc3rs.org.uk/our-funding-...
Apply for up to £25k to support industry-academic collaborations that advance 3Rs approaches in oncology, cardiovascular science and new approach methodologies: nc3rs.org.uk/our-funding-...
October 22, 2025 at 9:04 AM
⏳ NC3Rs-BBSRC Business Interaction Vouchers application deadline approaching: 16.00, Tuesday 4 November.
Apply for up to £25k to support industry-academic collaborations that advance 3Rs approaches in oncology, cardiovascular science and new approach methodologies: nc3rs.org.uk/our-funding-...
Apply for up to £25k to support industry-academic collaborations that advance 3Rs approaches in oncology, cardiovascular science and new approach methodologies: nc3rs.org.uk/our-funding-...
A new imaging system developed through our Transgene Track CRACK IT Challenge enables real-time, non-invasive monitoring of gene and cell therapies in rodents – reducing animal use and improving data quality in preclinical studies.
Learn more: nc3rs.org.uk/crackit/news...
Learn more: nc3rs.org.uk/crackit/news...
October 17, 2025 at 1:24 PM
A new imaging system developed through our Transgene Track CRACK IT Challenge enables real-time, non-invasive monitoring of gene and cell therapies in rodents – reducing animal use and improving data quality in preclinical studies.
Learn more: nc3rs.org.uk/crackit/news...
Learn more: nc3rs.org.uk/crackit/news...
Our latest report highlights the outcomes of the first UK funding call for infrastructure to support animal replacement methods. We made 11 awards (£3.95M) to establish national facilities and provide training opportunities across the UK: nc3rs.org.uk/news/investi...
Investing in infrastructure for animal replacement methods
Report highlights the outcomes of the first UK funding call for infrastructure to support animal replacement methods, delivered by the NC3Rs.
nc3rs.org.uk
October 16, 2025 at 1:30 PM
Our latest report highlights the outcomes of the first UK funding call for infrastructure to support animal replacement methods. We made 11 awards (£3.95M) to establish national facilities and provide training opportunities across the UK: nc3rs.org.uk/news/investi...
Thanks to the 320 attendees from 30 countries who joined us over two webinar sessions that explored model-specific refinements and practical tools to minimise laboratory animal suffering. If you missed the session the recording is now available.
👉 nc3rs.org.uk/3rs-resource...
👉 nc3rs.org.uk/3rs-resource...
October 15, 2025 at 2:37 PM
Thanks to the 320 attendees from 30 countries who joined us over two webinar sessions that explored model-specific refinements and practical tools to minimise laboratory animal suffering. If you missed the session the recording is now available.
👉 nc3rs.org.uk/3rs-resource...
👉 nc3rs.org.uk/3rs-resource...
NEW SURVEY. Do you manufacture, regulate or produce biological therapeutics? Help the NC3Rs shape the future of non-animal pyrogenicity testing of biologics: nc3rs.org.uk/our-portfoli...
Supporting 3Rs approaches in biologicals testing
nc3rs.org.uk
October 14, 2025 at 1:59 PM
NEW SURVEY. Do you manufacture, regulate or produce biological therapeutics? Help the NC3Rs shape the future of non-animal pyrogenicity testing of biologics: nc3rs.org.uk/our-portfoli...
Register now for an afternoon of networking and expert insights at an event that brings together researchers, clinicians and neurosurgeons to discuss the practicalities and potential of using human brain tissue to replace animal models in neuroscience.
“Using Human Brain Tissue in Research”
NC3Rs supported @nc3rs.bsky.social
Date & time: Friday, 7 November 2025 13:00–16:00
Prof Maria Thom
Mr Martin Gillies
Mr Ciaran S. Hill
Location: UCL Institute of Advanced Studies
Registration (event is free): www.eventbrite.co.uk/e/networking...
NC3Rs supported @nc3rs.bsky.social
Date & time: Friday, 7 November 2025 13:00–16:00
Prof Maria Thom
Mr Martin Gillies
Mr Ciaran S. Hill
Location: UCL Institute of Advanced Studies
Registration (event is free): www.eventbrite.co.uk/e/networking...
Networking Event: Using Human Brain Tissue in Research
Networking event connecting researchers, clinicians & neurosurgeons to discuss practical and ethical aspects of human brain tissue research
www.eventbrite.co.uk
October 13, 2025 at 12:26 PM
Register now for an afternoon of networking and expert insights at an event that brings together researchers, clinicians and neurosurgeons to discuss the practicalities and potential of using human brain tissue to replace animal models in neuroscience.
Join researchers, clinicians and neurosurgeons for an afternoon of expert insights and networking to discuss the practicalities and potential of using human brain tissue to replace animal models in neuroscience.
📅 Friday 7 November, 13.00 – 16.00
📍 UCL, London
Register: nc3rs.org.uk/events/using...
📅 Friday 7 November, 13.00 – 16.00
📍 UCL, London
Register: nc3rs.org.uk/events/using...
October 10, 2025 at 8:51 AM
Join researchers, clinicians and neurosurgeons for an afternoon of expert insights and networking to discuss the practicalities and potential of using human brain tissue to replace animal models in neuroscience.
📅 Friday 7 November, 13.00 – 16.00
📍 UCL, London
Register: nc3rs.org.uk/events/using...
📅 Friday 7 November, 13.00 – 16.00
📍 UCL, London
Register: nc3rs.org.uk/events/using...
Recordings available: nc3rs.org.uk/crackit/tech...
Watch presentations from six model developers to learn more about their technologies and explore new partnerships to access 3Rs approaches for your oncology research.
Watch presentations from six model developers to learn more about their technologies and explore new partnerships to access 3Rs approaches for your oncology research.
Are you interested in the latest 3Rs technologies in oncology research? Join us at our next Technology Partn3Ring webinar for opportunities to collaborate and access new 3Rs models.
📅 Wednesday 24 September, 14.00 – 15.15 (BST)
👉 Register now: nc3rs.org.uk/events/techn...
📅 Wednesday 24 September, 14.00 – 15.15 (BST)
👉 Register now: nc3rs.org.uk/events/techn...
October 3, 2025 at 12:06 PM
Recordings available: nc3rs.org.uk/crackit/tech...
Watch presentations from six model developers to learn more about their technologies and explore new partnerships to access 3Rs approaches for your oncology research.
Watch presentations from six model developers to learn more about their technologies and explore new partnerships to access 3Rs approaches for your oncology research.
We were delighted to welcome 12 BBSRC-funded PhD students to our annual summer school this year alongside NC3Rs-funded students. Our training for early career researchers focuses on their role as ambassadors for the 3Rs throughout their PhD and beyond.
💡 Read more: nc3rs.org.uk/news/trainin...
💡 Read more: nc3rs.org.uk/news/trainin...
October 1, 2025 at 9:16 AM
We were delighted to welcome 12 BBSRC-funded PhD students to our annual summer school this year alongside NC3Rs-funded students. Our training for early career researchers focuses on their role as ambassadors for the 3Rs throughout their PhD and beyond.
💡 Read more: nc3rs.org.uk/news/trainin...
💡 Read more: nc3rs.org.uk/news/trainin...
Please note that our Experimental Design Assistant (EDA) eda.nc3rs.org.uk will be offline tomorrow from 4pm (BST) for planned maintenance.
Full details 👇.
Full details 👇.
🚨⚠️The @nc3rs.bsky.social's Experimental Design Assistant (EDA) will be offline for planned maintenance on Tuesday 23 September from 4pm BST. We anticipate it will be back online by the morning of Wednesday 24 September. We apologise for any inconvenience caused.⚠️🚨
September 22, 2025 at 11:20 AM
Please note that our Experimental Design Assistant (EDA) eda.nc3rs.org.uk will be offline tomorrow from 4pm (BST) for planned maintenance.
Full details 👇.
Full details 👇.
Are you a researcher, developer, or industry/regulatory user of NAMs?
Join our webinar with @brittoxsoc.bsky.social on how AI can improve safety assessment and reduce reliance on animals: nc3rs.org.uk/events/artif...
⏰ Registration closes: 24 September, 14.00
📅 Webinar: 25 September, 14.00 – 16.00
Join our webinar with @brittoxsoc.bsky.social on how AI can improve safety assessment and reduce reliance on animals: nc3rs.org.uk/events/artif...
⏰ Registration closes: 24 September, 14.00
📅 Webinar: 25 September, 14.00 – 16.00
Webinar: Future perspectives on artificial intelligence in safety assessment
Three leading experts will discuss how AI and approaches such as machine learning can be used to improve toxicity prediction and reduce the reliance on animal models.
📅 25 September, 14.00
👉 nc3rs.org.uk/events/artif...
Three leading experts will discuss how AI and approaches such as machine learning can be used to improve toxicity prediction and reduce the reliance on animal models.
📅 25 September, 14.00
👉 nc3rs.org.uk/events/artif...
September 17, 2025 at 11:02 AM
Are you a researcher, developer, or industry/regulatory user of NAMs?
Join our webinar with @brittoxsoc.bsky.social on how AI can improve safety assessment and reduce reliance on animals: nc3rs.org.uk/events/artif...
⏰ Registration closes: 24 September, 14.00
📅 Webinar: 25 September, 14.00 – 16.00
Join our webinar with @brittoxsoc.bsky.social on how AI can improve safety assessment and reduce reliance on animals: nc3rs.org.uk/events/artif...
⏰ Registration closes: 24 September, 14.00
📅 Webinar: 25 September, 14.00 – 16.00
New report from the NC3Rs, in collaboration with @abpi.bsky.social and MHRA, explores how New Approach Methodologies (NAMs) can transform the way new medicines are developed, harnessing cutting edge human relevant technologies and reducing reliance on animal testing.
nc3rs.org.uk/news/incorpo...
nc3rs.org.uk/news/incorpo...
September 16, 2025 at 10:55 AM
New report from the NC3Rs, in collaboration with @abpi.bsky.social and MHRA, explores how New Approach Methodologies (NAMs) can transform the way new medicines are developed, harnessing cutting edge human relevant technologies and reducing reliance on animal testing.
nc3rs.org.uk/news/incorpo...
nc3rs.org.uk/news/incorpo...
Final week to register! Join us at our next Technology Partn3Ring webinar to collaborate with academics and SMEs developing the latest 3Rs technologies in cancer research: nc3rs.org.uk/events/techn...
⏰Registration closes: Tuesday 23 September, 14.00
📅 Webinar: Wednesday 24 September, 14.00 – 15.15
⏰Registration closes: Tuesday 23 September, 14.00
📅 Webinar: Wednesday 24 September, 14.00 – 15.15
Are you interested in the latest 3Rs technologies in oncology research? Join us at our next Technology Partn3Ring webinar for opportunities to collaborate and access new 3Rs models.
📅 Wednesday 24 September, 14.00 – 15.15 (BST)
👉 Register now: nc3rs.org.uk/events/techn...
📅 Wednesday 24 September, 14.00 – 15.15 (BST)
👉 Register now: nc3rs.org.uk/events/techn...
September 15, 2025 at 1:42 PM
Final week to register! Join us at our next Technology Partn3Ring webinar to collaborate with academics and SMEs developing the latest 3Rs technologies in cancer research: nc3rs.org.uk/events/techn...
⏰Registration closes: Tuesday 23 September, 14.00
📅 Webinar: Wednesday 24 September, 14.00 – 15.15
⏰Registration closes: Tuesday 23 September, 14.00
📅 Webinar: Wednesday 24 September, 14.00 – 15.15