Patrick Mulholland (He/Him)
@mulhollandlab.bsky.social
Alcohol Addiction Neuroscientist at a Medical University in Charleston SC; part time taxi driver for three active kids
Pinned
Here is a link to our DIY balance arm for fiber #photometry recordings in freely moving mice @drjrink.bsky.social
github.com/Patrick-Mulh...
github.com/Patrick-Mulh...
Reposted by Patrick Mulholland (He/Him)
Follow these links to apply to present and join the alcohol neuroscience research community!
GRS (Trainee pre-meeting, Feb 21-22, 2026): tinyurl.com/35zf3wte
GRC (Main meeting immediately following, Feb 22-27, 2026): tinyurl.com/44z957ve
GRS (Trainee pre-meeting, Feb 21-22, 2026): tinyurl.com/35zf3wte
GRC (Main meeting immediately following, Feb 22-27, 2026): tinyurl.com/44z957ve
August 29, 2025 at 1:17 PM
Follow these links to apply to present and join the alcohol neuroscience research community!
GRS (Trainee pre-meeting, Feb 21-22, 2026): tinyurl.com/35zf3wte
GRC (Main meeting immediately following, Feb 22-27, 2026): tinyurl.com/44z957ve
GRS (Trainee pre-meeting, Feb 21-22, 2026): tinyurl.com/35zf3wte
GRC (Main meeting immediately following, Feb 22-27, 2026): tinyurl.com/44z957ve
Reposted by Patrick Mulholland (He/Him)
Apply now for the Alcohol & the Nervous System GRS, Feb 21-22, 2026!
The GRS kicks off the GRC, giving early-career scientists the perfect platform to launch into a week of cutting-edge science. Submit your abstracts to both by Oct 10th for talk consideration! #alcoholGRC2026 #alcoholGRS2026
The GRS kicks off the GRC, giving early-career scientists the perfect platform to launch into a week of cutting-edge science. Submit your abstracts to both by Oct 10th for talk consideration! #alcoholGRC2026 #alcoholGRS2026
We are looking forward to the 2026 #Alcohol GRC in Ventura, CA! The main meeting starts Feb 22, 2026 (GRS Feb 21-22). For both, we will be selecting additional invited talks from the submitted abstracts. For consideration, submit your abstract by Oct 10! #alcoholGRC2026 #alcoholGRS2026
August 29, 2025 at 1:17 PM
Apply now for the Alcohol & the Nervous System GRS, Feb 21-22, 2026!
The GRS kicks off the GRC, giving early-career scientists the perfect platform to launch into a week of cutting-edge science. Submit your abstracts to both by Oct 10th for talk consideration! #alcoholGRC2026 #alcoholGRS2026
The GRS kicks off the GRC, giving early-career scientists the perfect platform to launch into a week of cutting-edge science. Submit your abstracts to both by Oct 10th for talk consideration! #alcoholGRC2026 #alcoholGRS2026
We are looking forward to the 2026 #Alcohol GRC in Ventura, CA! The main meeting starts Feb 22, 2026 (GRS Feb 21-22). For both, we will be selecting additional invited talks from the submitted abstracts. For consideration, submit your abstract by Oct 10! #alcoholGRC2026 #alcoholGRS2026
August 29, 2025 at 11:06 AM
We are looking forward to the 2026 #Alcohol GRC in Ventura, CA! The main meeting starts Feb 22, 2026 (GRS Feb 21-22). For both, we will be selecting additional invited talks from the submitted abstracts. For consideration, submit your abstract by Oct 10! #alcoholGRC2026 #alcoholGRS2026
Reposted by Patrick Mulholland (He/Him)
Voluntary wheel-running reduces harmful drinking in a genetic risk model for drinking to intoxication #alcoholawareness #alcohol
@angelaozburn.bsky.social
sciencedirect.com/science/arti...
@angelaozburn.bsky.social
sciencedirect.com/science/arti...
Voluntary wheel-running reduces harmful drinking in a genetic risk model for drinking to intoxication
Physical activity (PA) may provide an effective and equitable treatment option for addressing the harm associated with Alcohol Use Disorders (AUDs). W…
sciencedirect.com
August 7, 2025 at 1:03 PM
Voluntary wheel-running reduces harmful drinking in a genetic risk model for drinking to intoxication #alcoholawareness #alcohol
@angelaozburn.bsky.social
sciencedirect.com/science/arti...
@angelaozburn.bsky.social
sciencedirect.com/science/arti...
Reposted by Patrick Mulholland (He/Him)
NIAAA Director Dr. Koob's publication now online - A Conceptual Framework for the Intersection of Hyperalgesia and Hyperkatifeia in #Alcohol Addiction #alcoholawareness www.sciencedirect.com/science/arti...
A Conceptual Framework for the Intersection of Hyperalgesia and Hyperkatifeia in Alcohol Addiction
Alcohol use disorder is a chronically relapsing disorder that is characterized by compulsive drug seeking and is hypothesized to result from multiple …
www.sciencedirect.com
August 28, 2025 at 9:12 PM
NIAAA Director Dr. Koob's publication now online - A Conceptual Framework for the Intersection of Hyperalgesia and Hyperkatifeia in #Alcohol Addiction #alcoholawareness www.sciencedirect.com/science/arti...
Reposted by Patrick Mulholland (He/Him)
Alcohol, aging, and the gut microbiome: Intersections of immunity, barrier dysfunction, and disease @cristinallorente.bsky.social #alcoholawareness
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Alcohol, aging, and the gut microbiome: Intersections of immunity, barrier dysfunction, and disease
Alcohol consumption exerts complex, dose- and context-dependent effects on human health, particularly by influencing the gut microbiome, intestinal ba…
www.sciencedirect.com
August 28, 2025 at 9:14 PM
Alcohol, aging, and the gut microbiome: Intersections of immunity, barrier dysfunction, and disease @cristinallorente.bsky.social #alcoholawareness
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Reposted by Patrick Mulholland (He/Him)
Persistent inflammation does not promote aversion-resistant binge-like #alcohol drinking in rats @jmoronconcepcion.bsky.social #alcoholawareness www.sciencedirect.com/science/arti...
Persistent inflammation does not promote aversion-resistant binge-like alcohol drinking in rats
Chronic pain is a leading cause of disability, significantly decreases quality of life, and is highly co-morbid with substance use disorders, includin…
www.sciencedirect.com
August 28, 2025 at 9:16 PM
Persistent inflammation does not promote aversion-resistant binge-like #alcohol drinking in rats @jmoronconcepcion.bsky.social #alcoholawareness www.sciencedirect.com/science/arti...
Reposted by Patrick Mulholland (He/Him)
The Majchrowicz binge model of #alcohol dependence: A valid model for comparing male and female rats @nixonlab.bsky.social www.sciencedirect.com/science/arti...
The Majchrowicz binge model of alcohol dependence: A valid model for comparing male and female rats
Alcohol use disorders (AUD) among women have steadily risen over the past decade. This increase is due in part to increased rates of drinking among so…
www.sciencedirect.com
August 28, 2025 at 9:25 PM
The Majchrowicz binge model of #alcohol dependence: A valid model for comparing male and female rats @nixonlab.bsky.social www.sciencedirect.com/science/arti...
Reposted by Patrick Mulholland (He/Him)
Just published: #Alcohol use disorder exacerbates clinical and vascular risks differentially in psychiatric disorders sciencedirect.com/science/arti...
Alcohol use disorder exacerbates clinical and vascular risks differentially in psychiatric disorders
Alcohol Use Disorder (AUD) is a major public health concern with detrimental effects on cognitive and neurological function, yet its impact on psychia…
sciencedirect.com
July 14, 2025 at 3:36 PM
Just published: #Alcohol use disorder exacerbates clinical and vascular risks differentially in psychiatric disorders sciencedirect.com/science/arti...
Reposted by Patrick Mulholland (He/Him)
Just Published: Explaining increased efficacy of naltrexone in the treatment of #alcohol dependent patients with a family history of AUD: A systematic review on the role of reward sensitivity and sweet liking www.sciencedirect.com/science/arti...
Explaining increased efficacy of naltrexone in the treatment of alcohol dependent patients with a family history of alcohol use disorder: A systematic review on the role of reward sensitivity and swee...
A positive family history of alcohol use disorder (FHA+) is one of the strongest risk factors for developing alcohol use disorder (AUD) compared. Impo…
www.sciencedirect.com
July 14, 2025 at 3:38 PM
Just Published: Explaining increased efficacy of naltrexone in the treatment of #alcohol dependent patients with a family history of AUD: A systematic review on the role of reward sensitivity and sweet liking www.sciencedirect.com/science/arti...
Reposted by Patrick Mulholland (He/Him)
Just Published: Effect of high mobility group box 1 pathway inhibition on gene expression in the prefrontal cortex of mice exposed to #alcohol www.sciencedirect.com/science/arti...
Effect of high mobility group box 1 pathway inhibition on gene expression in the prefrontal cortex of mice exposed to alcohol
The high mobility group box 1 (HMGB1) pathway plays a pivotal role in the development of alcohol-induced brain injury. Glycyrrhizinic acid (GlyA) is w…
www.sciencedirect.com
July 14, 2025 at 3:39 PM
Just Published: Effect of high mobility group box 1 pathway inhibition on gene expression in the prefrontal cortex of mice exposed to #alcohol www.sciencedirect.com/science/arti...
Reposted by Patrick Mulholland (He/Him)
Just Published: Integrating TWAS and GWAS identifies gut microbiota–immune interactions to #alcohol dependence genetics in European sample www.sciencedirect.com/science/arti...
Integrating TWAS and GWAS identifies gut microbiota–immune interactions to alcohol dependence genetics in European sample
Alcohol dependence (AD) is a global public health concern with strong genetic characteristics. The purpose of this study was to explore the underlying…
www.sciencedirect.com
July 14, 2025 at 3:40 PM
Just Published: Integrating TWAS and GWAS identifies gut microbiota–immune interactions to #alcohol dependence genetics in European sample www.sciencedirect.com/science/arti...
Reposted by Patrick Mulholland (He/Him)
Just Published: #Alcohol consumption during early adulthood increases the vulnerability of locus coeruleus neurons and amyloid beta pathology in female APP/PS1 mice #AlcoholAwareness sciencedirect.com/science/arti...
Alcohol consumption during early adulthood increases the vulnerability of locus coeruleus neurons and amyloid beta pathology in female APP/PS1 mice
Alcohol use disorder is the most common substance misuse disorder and Alzheimer's disease (AD) is the most common neurodegenerative disease. Evidence …
sciencedirect.com
July 14, 2025 at 3:41 PM
Just Published: #Alcohol consumption during early adulthood increases the vulnerability of locus coeruleus neurons and amyloid beta pathology in female APP/PS1 mice #AlcoholAwareness sciencedirect.com/science/arti...
Reposted by Patrick Mulholland (He/Him)
Absolutely crushing it, congrats Kathy!!!!
a man applauds with the words way to go super proud of you behind him
ALT: a man applauds with the words way to go super proud of you behind him
media.tenor.com
June 26, 2025 at 1:45 AM
Absolutely crushing it, congrats Kathy!!!!
First the #RSA 3-min thesis inaugural winner and now the Gordis Award for @kathylindquist.bsky.social #proud-mentor #rsa2025 #rsa_isbra2025 @drjrink.bsky.social
June 26, 2025 at 1:41 AM
First the #RSA 3-min thesis inaugural winner and now the Gordis Award for @kathylindquist.bsky.social #proud-mentor #rsa2025 #rsa_isbra2025 @drjrink.bsky.social
Hey #alcohol researchers, what are non-NIH funding mechanisms to support alcohol research? Please share any information #rsa2025 #rsa_isbra2025
June 23, 2025 at 5:49 PM
Hey #alcohol researchers, what are non-NIH funding mechanisms to support alcohol research? Please share any information #rsa2025 #rsa_isbra2025
Reposted by Patrick Mulholland (He/Him)
Alcohol research community: thank you for your submissions to #Alcohol - we are excited to share that our Impact Factor has climbed to 2.9, our highest IF to date #rsa2025
@dougmat-uwec.bsky.social
@dougmat-uwec.bsky.social
June 20, 2025 at 1:44 PM
Alcohol research community: thank you for your submissions to #Alcohol - we are excited to share that our Impact Factor has climbed to 2.9, our highest IF to date #rsa2025
@dougmat-uwec.bsky.social
@dougmat-uwec.bsky.social
Congrats to @kathylindquist.bsky.social for winning the 3MT competition for preclinical students - way to go, Kathy!!! @drjrink.bsky.social
Exciting news! The first-ever RSA 3MT Competition is virtual on May 6th, 12-1pm ET, challenging students to present their research in 3 minutes with 1 slide.
Apply by March 10th for a chance to compete and win RSA Registration & Abstract cost prizes: conta.cc/4ku93qj #3MT #3minutethesis
Apply by March 10th for a chance to compete and win RSA Registration & Abstract cost prizes: conta.cc/4ku93qj #3MT #3minutethesis
May 6, 2025 at 9:28 PM
Congrats to @kathylindquist.bsky.social for winning the 3MT competition for preclinical students - way to go, Kathy!!! @drjrink.bsky.social
Reposted by Patrick Mulholland (He/Him)
oh hey, this paper is out now!
Led by JR Haun, former Kash lab postdoc!
pubmed.ncbi.nlm.nih.gov/40153436/
Led by JR Haun, former Kash lab postdoc!
pubmed.ncbi.nlm.nih.gov/40153436/
Septo-hypothalamic regulation of binge-like alcohol consumption by the nociceptin system - PubMed
High-intensity alcohol drinking during binge episodes contributes to the socioeconomic burden created by alcohol use disorders (AUDs), and nociceptin receptor (NOP) antagonists have emerged as a promi...
pubmed.ncbi.nlm.nih.gov
March 29, 2025 at 1:36 AM
oh hey, this paper is out now!
Led by JR Haun, former Kash lab postdoc!
pubmed.ncbi.nlm.nih.gov/40153436/
Led by JR Haun, former Kash lab postdoc!
pubmed.ncbi.nlm.nih.gov/40153436/
Reposted by Patrick Mulholland (He/Him)
Defending soon? Come postdoc with us - MUSC is a great place to prepare you for your next career move, in or outside of academia!
The Charleston Alcohol Research Center has an opening for a #postdoctoral fellowship on the #NIAAA T32 training grant - please spread the word and contact me if interested in working in beautiful Charleston, SC @drjrink.bsky.social
March 20, 2025 at 6:58 PM
Defending soon? Come postdoc with us - MUSC is a great place to prepare you for your next career move, in or outside of academia!
The Charleston Alcohol Research Center has an opening for a #postdoctoral fellowship on the #NIAAA T32 training grant - please spread the word and contact me if interested in working in beautiful Charleston, SC @drjrink.bsky.social
March 20, 2025 at 3:06 PM
The Charleston Alcohol Research Center has an opening for a #postdoctoral fellowship on the #NIAAA T32 training grant - please spread the word and contact me if interested in working in beautiful Charleston, SC @drjrink.bsky.social
Here is a link to our DIY balance arm for fiber #photometry recordings in freely moving mice @drjrink.bsky.social
github.com/Patrick-Mulh...
github.com/Patrick-Mulh...
March 17, 2025 at 4:48 PM
Here is a link to our DIY balance arm for fiber #photometry recordings in freely moving mice @drjrink.bsky.social
github.com/Patrick-Mulh...
github.com/Patrick-Mulh...
Dear science community, an amazing grad student with @drjrink.bsky.social and I lost her belongings in an apartment fire this morning. She and her dog are safe but needs your help. Please consider donating
www.gofundme.com/f/kathy-need...
www.gofundme.com/f/kathy-need...
Donate to Kathy Needs Your Help After Apartment Fire, organized by Patrick Mulholland
A graduate student in the Department of Neuroscience (Kathy L.) at MUSC … Patrick Mulholland needs your support for Kathy Needs Your Help After Apartment Fire
www.gofundme.com
February 15, 2025 at 3:03 PM
Dear science community, an amazing grad student with @drjrink.bsky.social and I lost her belongings in an apartment fire this morning. She and her dog are safe but needs your help. Please consider donating
www.gofundme.com/f/kathy-need...
www.gofundme.com/f/kathy-need...
Reposted by Patrick Mulholland (He/Him)
Flat 15% indirect costs across all grants (notes this will work because only 3 places - MIT, UMich, UAB - ever REFUSED a grant for lower than expected previous indirects). Impacts of this cut will presumably destroy research - current indirects are ~50%+
grants.nih.gov/grants/guide...
grants.nih.gov/grants/guide...
NOT-OD-25-068: Supplemental Guidance to the 2024 NIH Grants Policy Statement: Indirect Cost Rates
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Supplemental Guidance to the 2024 NIH Grants Policy Statement: Indirect Cost Rates NOT-OD-25-068. OD
grants.nih.gov
February 7, 2025 at 11:21 PM
Flat 15% indirect costs across all grants (notes this will work because only 3 places - MIT, UMich, UAB - ever REFUSED a grant for lower than expected previous indirects). Impacts of this cut will presumably destroy research - current indirects are ~50%+
grants.nih.gov/grants/guide...
grants.nih.gov/grants/guide...
Reposted by Patrick Mulholland (He/Him)
While I agree that UMAPs can be problematic, I also think that statisticians have a lot to answer for with regard to the general debasement of modern science towards p-values instead of critical thinking and model building. That has been far more damaging than a couple of silly plots.
January 26, 2025 at 5:21 PM
While I agree that UMAPs can be problematic, I also think that statisticians have a lot to answer for with regard to the general debasement of modern science towards p-values instead of critical thinking and model building. That has been far more damaging than a couple of silly plots.