Misha Rosenbach, MD
@misharosenbach.bsky.social
Dermatologist (medical derm, granulomas [sarcoid & more], neutrophilic dzs [PG/Sweets/etc], inpatient derm, drug reactions [SJS/DRESS], MedEd, climate & sustainability) @pennmedicine.bsky.social Residency PD @PennDerm. Views mine, not medical advice
Reposted by Misha Rosenbach, MD
Botulinum toxin injections were associated with high complete response rates for acute digital ischemia (93.1%), ischemic ulcers (90.1%), and gangrene (87.5%), with minimal adverse events. ja.ma/4rqaCs9
February 1, 2026 at 12:00 PM
Botulinum toxin injections were associated with high complete response rates for acute digital ischemia (93.1%), ischemic ulcers (90.1%), and gangrene (87.5%), with minimal adverse events. ja.ma/4rqaCs9
Reposted by Misha Rosenbach, MD
This case report describes a patient with a history of refractory acute myeloid leukemia who presented with white, spiny hyperkeratotic papules on his face and neck, and was subsequently diagnosed with trichodysplasia spinulosa. bit.ly/4tjXhDl
February 5, 2026 at 1:00 PM
This case report describes a patient with a history of refractory acute myeloid leukemia who presented with white, spiny hyperkeratotic papules on his face and neck, and was subsequently diagnosed with trichodysplasia spinulosa. bit.ly/4tjXhDl
Reposted by Misha Rosenbach, MD
📄 This case report describes large areas of erythema on the face, chest, and back with relatively clear boundaries and swollen hands with scattered skin-colored papules and nodules.
bit.ly/3ZgXYQe
bit.ly/3ZgXYQe
February 6, 2026 at 3:00 PM
📄 This case report describes large areas of erythema on the face, chest, and back with relatively clear boundaries and swollen hands with scattered skin-colored papules and nodules.
bit.ly/3ZgXYQe
bit.ly/3ZgXYQe
Reposted by Misha Rosenbach, MD
A woman in her 70s with rheumatoid arthritis who was receiving long-term immunosuppression (prednisolone and methotrexate) presented with a 6-month history of progressive papulonodules on her face and extremities.
📝 Take the Clinical Challenge:
ja.ma/4buHnzH
📝 Take the Clinical Challenge:
ja.ma/4buHnzH
February 11, 2026 at 1:00 PM
A woman in her 70s with rheumatoid arthritis who was receiving long-term immunosuppression (prednisolone and methotrexate) presented with a 6-month history of progressive papulonodules on her face and extremities.
📝 Take the Clinical Challenge:
ja.ma/4buHnzH
📝 Take the Clinical Challenge:
ja.ma/4buHnzH
Reposted by Misha Rosenbach, MD
Among patients with juvenile dermatomyositis, intermittent intravenous methylprednisolone pulse plus mycophenolate mofetil led to complete clinical response and remission in 93% of patients after a median 36 months of follow-up. ja.ma/4bG4449
February 12, 2026 at 1:00 PM
Among patients with juvenile dermatomyositis, intermittent intravenous methylprednisolone pulse plus mycophenolate mofetil led to complete clinical response and remission in 93% of patients after a median 36 months of follow-up. ja.ma/4bG4449
Reposted by Misha Rosenbach, MD
A man in his 30s presented with a 2-month history of hair loss on the entire scalp and the lateral portions of both eyebrows. Results of the hair-pull test were negative.
What is your diagnosis?
ja.ma/4661hgW
What is your diagnosis?
ja.ma/4661hgW
February 12, 2026 at 3:23 PM
A man in his 30s presented with a 2-month history of hair loss on the entire scalp and the lateral portions of both eyebrows. Results of the hair-pull test were negative.
What is your diagnosis?
ja.ma/4661hgW
What is your diagnosis?
ja.ma/4661hgW
Reposted by Misha Rosenbach, MD
Anifrolumab treatment in #LupusErythematosus was associated with significant reductions in systemic and cutaneous disease activity, while SIGLEC-1 expression decreased alongside clinical improvement.
ja.ma/4reY1YX
ja.ma/4reY1YX
February 13, 2026 at 2:00 PM
Anifrolumab treatment in #LupusErythematosus was associated with significant reductions in systemic and cutaneous disease activity, while SIGLEC-1 expression decreased alongside clinical improvement.
ja.ma/4reY1YX
ja.ma/4reY1YX
Reposted by Misha Rosenbach, MD
Case report describes a patient in his 50s with immunoglobulin A vasculitis with monoclonal B-cell lymphocytosis who was successfully treated with zanubrutinib after failure of multiple treatments. ja.ma/49HVRuF
January 9, 2026 at 3:00 PM
Case report describes a patient in his 50s with immunoglobulin A vasculitis with monoclonal B-cell lymphocytosis who was successfully treated with zanubrutinib after failure of multiple treatments. ja.ma/49HVRuF
Reposted by Misha Rosenbach, MD
Activating #EGFR variants were identified in early-onset, severe generalized #AcanthosisNigricans with pulmonary nodules; EGFR inhibitor therapy improved both skin and lung disease. ja.ma/4bw0Rnp
January 15, 2026 at 3:00 PM
Activating #EGFR variants were identified in early-onset, severe generalized #AcanthosisNigricans with pulmonary nodules; EGFR inhibitor therapy improved both skin and lung disease. ja.ma/4bw0Rnp
Reposted by Misha Rosenbach, MD
A 20-year-old woman presented with 9 days of pain and decreased vision in the right eye, as well as 2 weeks of a rash and gum swelling. Fever, dyspnea, and hemoptysis developed. Read the full case details: nej.md/45acJaR
#MedSky #DermSky #Ophthalmology
#MedSky #DermSky #Ophthalmology
January 15, 2026 at 5:26 PM
A 20-year-old woman presented with 9 days of pain and decreased vision in the right eye, as well as 2 weeks of a rash and gum swelling. Fever, dyspnea, and hemoptysis developed. Read the full case details: nej.md/45acJaR
#MedSky #DermSky #Ophthalmology
#MedSky #DermSky #Ophthalmology
Reposted by Misha Rosenbach, MD
This case report describes a man in his 30s who presented for evaluation of a 3-week history of irritation, redness, and photophobia in both eyes.
ja.ma/3KOUwsx
ja.ma/3KOUwsx
December 25, 2025 at 1:00 PM
This case report describes a man in his 30s who presented for evaluation of a 3-week history of irritation, redness, and photophobia in both eyes.
ja.ma/3KOUwsx
ja.ma/3KOUwsx
Reposted by Misha Rosenbach, MD
Botulinum toxin injections were associated with high complete response rates for acute digital ischemia (93.1%), ischemic ulcers (90.1%), and gangrene (87.5%), with minimal adverse events.
ja.ma/4phELs4
ja.ma/4phELs4
January 1, 2026 at 2:00 PM
Botulinum toxin injections were associated with high complete response rates for acute digital ischemia (93.1%), ischemic ulcers (90.1%), and gangrene (87.5%), with minimal adverse events.
ja.ma/4phELs4
ja.ma/4phELs4
Reposted by Misha Rosenbach, MD
Lamellar ichthyosis (LI) is a rare autosomal recessive disorder characterized by widespread, thick, platelike scales.
This case report describes 2 siblings in their 20s with lamellar ichthyosis treated with acitretin and dupilumab. ja.ma/45mH99S
This case report describes 2 siblings in their 20s with lamellar ichthyosis treated with acitretin and dupilumab. ja.ma/45mH99S
January 3, 2026 at 1:00 PM
Lamellar ichthyosis (LI) is a rare autosomal recessive disorder characterized by widespread, thick, platelike scales.
This case report describes 2 siblings in their 20s with lamellar ichthyosis treated with acitretin and dupilumab. ja.ma/45mH99S
This case report describes 2 siblings in their 20s with lamellar ichthyosis treated with acitretin and dupilumab. ja.ma/45mH99S
Reposted by Misha Rosenbach, MD
A woman in her 70s presented with a 5-year history of pruritic, thickened plaques involving the trunk and extremities. Despite intermittent treatment with antihistamines and glucocorticoids, the condition progressed.
Read the full case report: ja.ma/49kbXJD
Read the full case report: ja.ma/49kbXJD
January 7, 2026 at 2:00 PM
A woman in her 70s presented with a 5-year history of pruritic, thickened plaques involving the trunk and extremities. Despite intermittent treatment with antihistamines and glucocorticoids, the condition progressed.
Read the full case report: ja.ma/49kbXJD
Read the full case report: ja.ma/49kbXJD
Reposted by Misha Rosenbach, MD
An adolescent female presented with 3 days of progressive abdominal pain and reported that a rash first appeared nearly 1 year earlier on her left wrist and gradually spread over several weeks.
What is your diagnosis? ja.ma/4qItEcH
What is your diagnosis? ja.ma/4qItEcH
January 8, 2026 at 3:00 PM
An adolescent female presented with 3 days of progressive abdominal pain and reported that a rash first appeared nearly 1 year earlier on her left wrist and gradually spread over several weeks.
What is your diagnosis? ja.ma/4qItEcH
What is your diagnosis? ja.ma/4qItEcH
Reposted by Misha Rosenbach, MD
A 38-year-old woman presented with a 12-month history of annular plaques on the forehead, cheeks, and neck. Skin biopsy revealed noncaseating epithelioid granulomas with sparse lymphocytic infiltration in the superficial dermis. Read the full case details: nej.md/3L26Llk
#MedSky #DermSky #PulmSky
#MedSky #DermSky #PulmSky
December 24, 2025 at 11:00 PM
A 38-year-old woman presented with a 12-month history of annular plaques on the forehead, cheeks, and neck. Skin biopsy revealed noncaseating epithelioid granulomas with sparse lymphocytic infiltration in the superficial dermis. Read the full case details: nej.md/3L26Llk
#MedSky #DermSky #PulmSky
#MedSky #DermSky #PulmSky
Reposted by Misha Rosenbach, MD
An 80-year-old man presented with a 4-day history of a rash on his abdomen. Physical examination was notable for periumbilical erythema and a small gray protrusion in the umbilicus. Read the full case details: nej.md/4pYF5NO
@i-med.ac.at #MedSky #DermSky
@i-med.ac.at #MedSky #DermSky
January 7, 2026 at 8:23 PM
An 80-year-old man presented with a 4-day history of a rash on his abdomen. Physical examination was notable for periumbilical erythema and a small gray protrusion in the umbilicus. Read the full case details: nej.md/4pYF5NO
@i-med.ac.at #MedSky #DermSky
@i-med.ac.at #MedSky #DermSky
Reposted by Misha Rosenbach, MD
So little was known 18 years ago when I started researching climate comms. I'm blown away by how much we now know. This study, led by the incomparable Jan Voelkel with his all-star band, and released today in @natclimate.nature.com confirms that many distinct message strategies can work...
A registered report megastudy on the persuasiveness of the most-cited climate messages - Nature Climate Change
How to effectively communicate climate change to the public has long been studied and debated. Through a registered report megastudy, researchers tested the ten most-cited climate change messaging str...
www.nature.com
January 6, 2026 at 12:17 AM
So little was known 18 years ago when I started researching climate comms. I'm blown away by how much we now know. This study, led by the incomparable Jan Voelkel with his all-star band, and released today in @natclimate.nature.com confirms that many distinct message strategies can work...
Reposted by Misha Rosenbach, MD
This is purpura fulminans, a severe complication of meningitis (which as of today is no longer on our universal vaccine schedule)
Micro clots & bleeding into the skin cause skin & tissue death. It’s more common in kids & associated with 20-70% mortality.
Those who survive often lose limbs.
Micro clots & bleeding into the skin cause skin & tissue death. It’s more common in kids & associated with 20-70% mortality.
Those who survive often lose limbs.
January 6, 2026 at 1:35 AM
This is purpura fulminans, a severe complication of meningitis (which as of today is no longer on our universal vaccine schedule)
Micro clots & bleeding into the skin cause skin & tissue death. It’s more common in kids & associated with 20-70% mortality.
Those who survive often lose limbs.
Micro clots & bleeding into the skin cause skin & tissue death. It’s more common in kids & associated with 20-70% mortality.
Those who survive often lose limbs.
Reposted by Misha Rosenbach, MD
Year 1 data on congestion pricing in Manhattan…
* Vehicle traffic: -11%
* Foot traffic: +3.4%
* Storefront vacancy: -0.9%
* Pollution: -22%
* Revenue for mass transit: $548M
So YES this has been a huge success.
* Vehicle traffic: -11%
* Foot traffic: +3.4%
* Storefront vacancy: -0.9%
* Pollution: -22%
* Revenue for mass transit: $548M
So YES this has been a huge success.
December 23, 2025 at 2:00 PM
Year 1 data on congestion pricing in Manhattan…
* Vehicle traffic: -11%
* Foot traffic: +3.4%
* Storefront vacancy: -0.9%
* Pollution: -22%
* Revenue for mass transit: $548M
So YES this has been a huge success.
* Vehicle traffic: -11%
* Foot traffic: +3.4%
* Storefront vacancy: -0.9%
* Pollution: -22%
* Revenue for mass transit: $548M
So YES this has been a huge success.
Reposted by Misha Rosenbach, MD
The US #measles count for this year has topped 2,000 cases for the first time since 1992. These are confirmed cases only, ie there have been more. 3 reported deaths.
The vast majority of the cases are in unvaccinated kids & adults. 11% needed hospitalization. www.cdc.gov/measles/data...
The vast majority of the cases are in unvaccinated kids & adults. 11% needed hospitalization. www.cdc.gov/measles/data...
December 23, 2025 at 10:06 PM
The US #measles count for this year has topped 2,000 cases for the first time since 1992. These are confirmed cases only, ie there have been more. 3 reported deaths.
The vast majority of the cases are in unvaccinated kids & adults. 11% needed hospitalization. www.cdc.gov/measles/data...
The vast majority of the cases are in unvaccinated kids & adults. 11% needed hospitalization. www.cdc.gov/measles/data...
Reposted by Misha Rosenbach, MD
In a Review Article on measles, Lien Anh Ha Do, MD, PhD, and Kim Mulholland, MB, BS, MD, review the epidemiology, clinical presentation, and associated illnesses as well as treatment and prevention strategies. Read the full review: nej.md/4lmC1Ir
#MedSky #PedSky #IDSky
#MedSky #PedSky #IDSky
December 19, 2025 at 2:03 PM
In a Review Article on measles, Lien Anh Ha Do, MD, PhD, and Kim Mulholland, MB, BS, MD, review the epidemiology, clinical presentation, and associated illnesses as well as treatment and prevention strategies. Read the full review: nej.md/4lmC1Ir
#MedSky #PedSky #IDSky
#MedSky #PedSky #IDSky
Reposted by Misha Rosenbach, MD
A 72-year-old woman presented with a 3.5-month history of an enlarging, painless lump on her cheek. Examination showed a dome-shaped, reddish nodule on the left cheek, with a shiny surface and central hemorrhagic crust. Read the full case details: nej.md/3MDwXU5
#MedSky #DermSky #Oncology
#MedSky #DermSky #Oncology
December 19, 2025 at 8:31 PM
A 72-year-old woman presented with a 3.5-month history of an enlarging, painless lump on her cheek. Examination showed a dome-shaped, reddish nodule on the left cheek, with a shiny surface and central hemorrhagic crust. Read the full case details: nej.md/3MDwXU5
#MedSky #DermSky #Oncology
#MedSky #DermSky #Oncology
Reposted by Misha Rosenbach, MD
HPV vaccination could prevent most cervical cancers, but only 27% of eligible adolescent girls worldwide have received the vaccine. Data suggest that a single dose may be protective. Research findings from the ESCUDDO trial are summarized in a new Quick Take video. nej.md/3MFcHBr
#MedSky #IDSky
#MedSky #IDSky
December 21, 2025 at 2:00 PM
HPV vaccination could prevent most cervical cancers, but only 27% of eligible adolescent girls worldwide have received the vaccine. Data suggest that a single dose may be protective. Research findings from the ESCUDDO trial are summarized in a new Quick Take video. nej.md/3MFcHBr
#MedSky #IDSky
#MedSky #IDSky
Reposted by Misha Rosenbach, MD
Monthly vixarelimab led to rapid and sustained improvement in pruritus and lesion severity for adults with #PrurigoNodularis, with no serious drug-related adverse events reported.
ja.ma/4pOaUJ4
ja.ma/4pOaUJ4
December 17, 2025 at 4:30 PM
Monthly vixarelimab led to rapid and sustained improvement in pruritus and lesion severity for adults with #PrurigoNodularis, with no serious drug-related adverse events reported.
ja.ma/4pOaUJ4
ja.ma/4pOaUJ4