Mike Barnkob
@mikebarnkob.bsky.social
M.D, PhD with a day job as a clinical immunologist, but moonlights as a CAR-T researcher. Interested in: synbio, cancer & cellular therapies.
Wait what, so the universe a gigantic cell or what is going on here?
April 25, 2025 at 9:26 PM
Wait what, so the universe a gigantic cell or what is going on here?
Assessing CAR T cells cytotoxic capacity at the single-cell level can be tricky.
Here we provide a method for encapsulating >500.000 single CAR T cells with single target cells in droplets together with reagents to examine killing using standard flow cytometry:
app.jove.com/t/67657/drop...
Here we provide a method for encapsulating >500.000 single CAR T cells with single target cells in droplets together with reagents to examine killing using standard flow cytometry:
app.jove.com/t/67657/drop...
March 27, 2025 at 7:01 PM
Assessing CAR T cells cytotoxic capacity at the single-cell level can be tricky.
Here we provide a method for encapsulating >500.000 single CAR T cells with single target cells in droplets together with reagents to examine killing using standard flow cytometry:
app.jove.com/t/67657/drop...
Here we provide a method for encapsulating >500.000 single CAR T cells with single target cells in droplets together with reagents to examine killing using standard flow cytometry:
app.jove.com/t/67657/drop...