@miershawig.bsky.social
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If you are into #posttranscriptional modifications, gut #inflammation, #immunology or #gutmicrobiome check out our latest work @jem.org 👇
Big team effort @miershawig.bsky.social
@connyves.bsky.social
Big thanks to @fwf-at.bsky.social for funding!
Big team effort @miershawig.bsky.social
@connyves.bsky.social
Big thanks to @fwf-at.bsky.social for funding!
[email protected] group shows that RNA editing of the #actin cross-linker FLNA is similarly regulated in mice & humans and that the targeted induction of edited FLNAR in myeloid cells governs resistance to DSS-induced #colitis, revealing its potential in #IBD therapy rupress.org/jem/article/...
June 8, 2025 at 5:43 PM
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Reposted
Check out our exciting paper by @asmafarhat.bsky.social in @scienceimmuno.bsky.social.
In a nutshell: in lung fibrosis, the age of the bone marrow matters more than the age of lung tissue.
check out the threat by Asma below 👇
Thanks to co-lead @miershawig.bsky.social and all collaborators :)
In a nutshell: in lung fibrosis, the age of the bone marrow matters more than the age of lung tissue.
check out the threat by Asma below 👇
Thanks to co-lead @miershawig.bsky.social and all collaborators :)
1/ Excited to share my first-ever first-author paper out now in Science Immunology! from @knapplab.bsky.social and co-supervised by @miershawig.bsky.social
We show that hematopoietic aging, independent of lung tissue aging, is sufficient to exacerbate fibrosis.
🔗 www.science.org/doi/10.1126/...
We show that hematopoietic aging, independent of lung tissue aging, is sufficient to exacerbate fibrosis.
🔗 www.science.org/doi/10.1126/...
An aging bone marrow exacerbates lung fibrosis by fueling profibrotic macrophage persistence
Hematopoietic aging drives lung fibrosis and profibrotic macrophage influx, stalling their maturation via reduced Treg-derived IL-10.
www.science.org
March 31, 2025 at 3:40 PM
Check out our exciting paper by @asmafarhat.bsky.social in @scienceimmuno.bsky.social.
In a nutshell: in lung fibrosis, the age of the bone marrow matters more than the age of lung tissue.
check out the threat by Asma below 👇
Thanks to co-lead @miershawig.bsky.social and all collaborators :)
In a nutshell: in lung fibrosis, the age of the bone marrow matters more than the age of lung tissue.
check out the threat by Asma below 👇
Thanks to co-lead @miershawig.bsky.social and all collaborators :)
Reposted
1/ Excited to share my first-ever first-author paper out now in Science Immunology! from @knapplab.bsky.social and co-supervised by @miershawig.bsky.social
We show that hematopoietic aging, independent of lung tissue aging, is sufficient to exacerbate fibrosis.
🔗 www.science.org/doi/10.1126/...
We show that hematopoietic aging, independent of lung tissue aging, is sufficient to exacerbate fibrosis.
🔗 www.science.org/doi/10.1126/...
An aging bone marrow exacerbates lung fibrosis by fueling profibrotic macrophage persistence
Hematopoietic aging drives lung fibrosis and profibrotic macrophage influx, stalling their maturation via reduced Treg-derived IL-10.
www.science.org
March 28, 2025 at 7:10 PM
1/ Excited to share my first-ever first-author paper out now in Science Immunology! from @knapplab.bsky.social and co-supervised by @miershawig.bsky.social
We show that hematopoietic aging, independent of lung tissue aging, is sufficient to exacerbate fibrosis.
🔗 www.science.org/doi/10.1126/...
We show that hematopoietic aging, independent of lung tissue aging, is sufficient to exacerbate fibrosis.
🔗 www.science.org/doi/10.1126/...