Melissa Cooper, PhD
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melcooperphd.bsky.social
Melissa Cooper, PhD
@melcooperphd.bsky.social
NYU PostDoc (Liddelow/Chao) and Leon Levy Fellow in Neuroscience studying ⭐astrocyte⭐ networks! Formerly @ Vanderbilt. Neurodegeneration, visual system, gap junctions, glia, and all things microscopy. MelCooperPhD.com
Now on bioRxiv! Astrocytes in one brain region (cyan) communicate in expansive networks (magenta). Through tool development, tissue clearing, and many hours on our @zeiss-microscopy.bsky.social Z1, we now know these networks are repeatable across mice, plastic, and specific.
doi.org/10.1101/2025...
July 22, 2025 at 8:54 PM
Hippocampal vasculature is so pretty 😍
(mouse hippocampus perfused with Tomato Lectin and cleared)
#Neuroscience #Microscopy
May 14, 2025 at 9:25 PM
An old favorite of mine - this retinal astrocyte (GFAP) looks like it’s dancing among blood vessels.

#science #glia #microscopy
April 17, 2025 at 2:48 PM
Imaging these astrocytes on the surface of cleared brains was a blast!
April 16, 2025 at 3:20 PM
Fresh off the press! We found that degeneration in one retina causes astrocytes to respond retinotopically across *both* hemispheres of the brain. Perhaps astrocytes across the CNS are able to coordinate their responses more than we anticipated... www.pnas.org/doi/10.1073/...
March 10, 2025 at 9:13 PM
Hello, everyone! Please enjoy one of my favorite micrographs while I finally get set up over here. Vasculature (magenta, perfused lectin), GFAP (cyan), and cx43 (green) in a conditional astrocyte cx43 knockout mouse, demonstrating that cx43 is lost from astrocytes but not pericytes after tamoxifen.
January 26, 2025 at 3:51 PM