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Massive Photonics
@massivephotonics.bsky.social
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THE DNA-PAINT COMPANY. We offer comprehensive DNA-PAINT labeling kits & DNA-PAINT solutions such as services and collaborations. #SMLM #superresolution #DNAPAINT #microscopy
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𝗧𝗮𝘂 𝗻𝗮𝗻𝗼-𝗮𝗴𝗴𝗿𝗲𝗴𝗮𝘁𝗲 𝘁𝗿𝗮𝗻𝘀𝗶𝘁𝗶𝗼𝗻𝘀 𝗶𝗻 𝗔𝗹𝘇𝗵𝗲𝗶𝗺𝗲𝗿'𝘀 𝗗𝗶𝘀𝗲𝗮𝘀𝗲 𝗿𝗲𝘃𝗲𝗮𝗹𝗲𝗱 𝗯𝘆 𝗗𝗡𝗔-𝗣𝗔𝗜𝗡𝗧

Full study: doi.org/10.1002/advs...

Authors used our anti-mouse and anti-rabbit DNA-PAINT kits for tau visualization in brain tissue sections.

Congratulations to all authors!!

#DNAPAINT #SMLM #MassivePhotonics
Morphological and Hyperphosphorylation Transitions of Nanoscale Tau Aggregates in Alzheimer's Disease
Super-resolution microscopy identifies nano-sized tau aggregates (nano-aggregates) and reveals distinct transitions in their morphology and phosphorylation profiles across control, Primary Age-Relate...
doi.org
November 25, 2025 at 10:42 AM
massivephotonics.bsky.social
🚀 𝗜𝗻𝘁𝗿𝗼𝗱𝘂𝗰𝗶𝗻𝗴 𝗠𝗔𝗦𝗦𝗜𝗩𝗘-𝗥𝗡𝗔-𝗙𝗜𝗦𝗛 𝗣𝗿𝗼𝗯𝗲𝘀 𝗮𝗻𝗱 𝗕𝘂𝗳𝗳𝗲𝗿 𝗞𝗶𝘁𝘀 𝗶𝗺𝗮𝗴𝗶𝗻𝗴 of RNA targets 𝘂𝘀𝗶𝗻𝗴 𝗗𝗡𝗔-𝗣𝗔𝗜𝗡𝗧 𝗺𝗶𝗰𝗿𝗼𝘀𝗰𝗼𝗽𝘆.
🔗: www.massive-photonics.com/product-cate...

#SMLM #DNAPAINT #RNAImaging #RNAFISH #Microscopy #MassivePhotonics
November 18, 2025 at 1:03 PM
massivephotonics.bsky.social
New pre-print alert! “𝟯𝗗 𝗠𝗜𝗡𝗙𝗟𝗨𝗫 𝗰𝗼𝗺𝗯𝗶𝗻𝗲𝗱 𝘄𝗶𝘁𝗵 𝗗𝗡𝗔-𝗣𝗔𝗜𝗡𝗧 𝗿𝗲𝘀𝗼𝗹𝘃𝗲𝘀 𝘁𝗵𝗲 𝗮𝗿𝗿𝗮𝗻𝗴𝗲𝗺𝗲𝗻𝘁 𝗼𝗳 𝗕𝗮𝘀𝘀𝗼𝗼𝗻 𝗮𝘁 𝗮𝗰𝘁𝗶𝘃𝗲 𝘇𝗼𝗻𝗲𝘀” Congrats to all authors!!

www.biorxiv.org/content/10.1...

#MINFLUX #DNAPAINT #MassivePhotonics #Microscopy #Bassoon
3D MINFLUX combined with DNA-PAINT resolves the arrangement of Bassoon at active zones
Neurotransmitter release and membrane retrieval at active zones require precise spatial and temporal coordination relying on an intricate molecular machinery. However, the exact nano-structural organi...
www.biorxiv.org
October 16, 2025 at 7:43 AM
Reposted by Massive Photonics
abbelight.bsky.social
Join us & Massive Photonics on 23 Oct 2025 (4–5 PM CET) for a webinar with Prof. Ralf Jungmann, KOL on DNA-PAINT!

Discover how single-molecule #SpatialOmics is reshaping #BioImaging.

🎁 Win a Smart DNA-PAINT Kit!

Register now: us06web.zoom.us/webinar/regi...

#DNAPAINT #Microscopy #SMLM
October 8, 2025 at 1:35 PM
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Don’t forget to come by our booth at #SeeingIsBelieving2025!! We can't wait to chat 🧬 🔬

📍Booth No. 6

#DNAPAINT #SMLM #Superresolution #Microscopy
October 9, 2025 at 7:28 AM
massivephotonics.bsky.social
🧬 𝗡𝗲𝘄 𝗣𝗿𝗼𝗱𝘂𝗰𝘁 𝗟𝗮𝘂𝗻𝗰𝗵! 🧬The highly-requested 𝗮𝗻𝘁𝗶-𝗛𝗮𝗹𝗼 𝗗𝗡𝗔-𝗣𝗔𝗜𝗡𝗧 𝗸𝗶𝘁 is finally here!
Reveal nanoscale organization of Halo-tagged proteins with our plug-and-play DNA-PAINT kit.

🔗Learn More: www.massive-photonics.com/product-cate...
September 24, 2025 at 7:30 AM
massivephotonics.bsky.social
🔬 𝗪𝗵𝗶𝗰𝗵 𝗗𝗡𝗔-𝗣𝗔𝗜𝗡𝗧 𝘀𝗲𝗾𝘂𝗲𝗻𝗰𝗲 𝗶𝘀 𝗿𝗶𝗴𝗵𝘁 𝗳𝗼𝗿 𝘆𝗼𝘂?
Our #DNAPAINT Labeling Kits let you choose the balance of 𝘀𝗽𝗲𝗲𝗱 𝗮𝗻𝗱 𝗿𝗲𝘀𝗼𝗹𝘂𝘁𝗶𝗼𝗻 that fits your research.

⭐DNA-PAINT kits: www.massive-photonics.com/product-cate...
⭐FAST DNA-PAINT kits: www.massive-photonics.com/product-cate...
September 18, 2025 at 12:40 PM
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🚀 New Product Launch! 🚀
Ready to push your imaging to 𝘀𝘂𝗯-𝗻𝗮𝗻𝗼𝗺𝗲𝘁𝗲𝗿 𝘀𝗽𝗮𝘁𝗶𝗮𝗹 𝗿𝗲𝘀𝗼𝗹𝘂𝘁𝗶𝗼𝗻? Introducing our newest 𝗥𝗘𝗦𝗜 𝗞𝗶𝘁 𝗳𝗼𝗿 𝗔𝗟𝗙𝗔-𝘁𝗮𝗴𝗴𝗲𝗱 𝗽𝗿𝗼𝘁𝗲𝗶𝗻𝘀!
🔗 www.massive-photonics.com/product-cate...

#SMLM #RESI #DNAPAINT #Microscopy #nuclearpore
DNA-PAINT and RESI imaging of ALFA-tagged nuclear pore protein Nup96 using the RESI anti-ALFA kit. For RESI imaging, four Exchange-PAINT rounds were performed using a mixture of anti-ALFA single-domain antibodies carrying docking strands F1, F2, F3, and F4 (10,000 frames per round,100 ms integration time, ~ 80 min total imaging time). Image post-processing was carried out using the open-source DNA-PAINT analysis software Picasso's RESI module. For classic DNA-PAINT, all four imager strands were added to the sample simultaneously. DNA-PAINT and RESI imaging of ALFA-tagged nuclear pore protein Nup96 using the RESI anti-ALFA kit. For RESI imaging, four Exchange-PAINT rounds were performed using a mixture of anti-ALFA single-domain antibodies carrying docking strands F1, F2, F3, and F4 (10,000 frames per round,100 ms integration time, ~ 80 min total imaging time). Image post-processing was carried out using the open-source DNA-PAINT analysis software Picasso's RESI module. For classic DNA-PAINT, all four imager strands were added to the sample simultaneously.
September 11, 2025 at 8:52 AM
massivephotonics.bsky.social
🚀 New to DNA-PAINT? We make getting started simple.

Check out our 𝗽𝗹𝘂𝗴-𝗮𝗻𝗱-𝗽𝗹𝗮𝘆 #DNAPAINT 𝗹𝗮𝗯𝗲𝗹𝗶𝗻𝗴 𝗮𝗻𝗱 𝗶𝗺𝗮𝗴𝗶𝗻𝗴 𝗸𝗶𝘁𝘀:
✅ Seamless integration into immunostaining workflows
✅ Wide range of kits designed for various targets
✅ Includes all labeling & imaging reagents needed

🔗 massive-photonics.com
September 4, 2025 at 7:47 AM
massivephotonics.bsky.social
📢 Don’t forget to stop by our booth at #SMLMS2025!

We’re excited to share how our #DNAPAINT solutions and labeling kits can help you unlock nanoscale insights 🔬🧬

📍WP Building Foyer, near the windows
August 28, 2025 at 9:53 AM
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📢 We're heading to Single Molecule Localization Microscopy Symposium 2025 in Bonn!

📍 Stop by our booth in the foyer of the WP building to say hello and discuss how our DNA-PAINT kits and solutions enable multiplexed nanoscale imaging.

#SMLM #SMLMS2025 #DNAPAINT
August 25, 2025 at 12:17 PM
massivephotonics.bsky.social
I𝗺𝗺𝘂𝗻𝗼𝗹𝗮𝗯𝗲𝗹𝗶𝗻𝗴 𝘆𝗼𝘂𝗿 𝘀𝗮𝗺𝗽𝗹𝗲𝘀 𝘂𝘀𝗶𝗻𝗴 𝗽𝗿𝗶𝗺𝗮𝗿𝘆 𝗮𝗻𝘁𝗶𝗯𝗼𝗱𝗶𝗲𝘀? Take your imaging to nanoscale resolution with our 𝗽𝗹𝘂𝗴-𝗮𝗻𝗱-𝗽𝗹𝗮𝘆 𝗗𝗡𝗔-𝗣𝗔𝗜𝗡𝗧 𝘀𝗲𝗰𝗼𝗻𝗱𝗮𝗿𝘆 𝗯𝗶𝗻𝗱𝗲𝗿 𝗸𝗶𝘁𝘀.

🔗 www.massive-photonics.com/product-cate...

#DNAPAINT #SuperResolution #SMLM #Microscopy
DNA-PAINT samples/images generated using our secondary binder kits: 🔹 Paxillin & Vimentin – Massive-sdAB-FAST 2-Plex Kit 🔹 Tom20 & HSP60 – Massive-AB 2-Plex Kit 🔹 Tom20 – Massive-sdAB 1-Plex Kit 🔹 Tubulin –= Massive-sdAB-FAST 1-Plex Kit AB = antibody | sdAB = single-domain antibody
August 7, 2025 at 7:51 AM
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𝗠𝗲𝘀𝘀𝗮𝗴𝗲 𝘂𝘀 𝗱𝗶𝗿𝗲𝗰𝘁𝗹𝘆—𝘄𝗲’𝗿𝗲 𝗵𝗲𝗿𝗲 𝘁𝗼 𝗵𝗲𝗹𝗽.
We’ve added a new WhatsApp chat feature to our website! 🚀 Need help navigating or have product questions?
👉 www.massive-photonics.com
DNA-PAINT Labeling Kits for Super-Resolution Imaging
Massive-Photonics offers ready-to-use labelling kits for DNA-PAINT based super-resolution imaging.
www.massive-photonics.com
August 6, 2025 at 8:54 AM
massivephotonics.bsky.social
🚨 New Publication Alert 🚨
Researchers achieved ångström resolution imaging of cell-surface glycans of the glycocalyx using RESI microscopy, a DNA-PAINT based technology, and metabolic labeling.

🔗 www.nature.com/articles/s41...

#DNAPAINT #SuperResolution #RESI #Glycobiology #SMLM
Ångström-resolution imaging of cell-surface glycans - Nature Nanotechnology
By combining bioorthogonal metabolic labelling and resolution enhancement through sequential imaging of DNA barcodes, the molecular organization of individual sugars in the native glycocalyx has been ...
www.nature.com
July 28, 2025 at 1:58 PM
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🔬 𝗕𝗲𝗵𝗶𝗻𝗱 𝘁𝗵𝗲 𝗕𝗶𝗻𝗱𝗲𝗿𝘀: 𝗠𝗲𝗲𝘁 𝗝ü𝗿𝗴𝗲𝗻 𝗦𝗰𝗵𝗺𝗶𝗲𝗱🔬
Today, we’re spotlighting Dr. Jürgen Schmied, CEO and co-founder of Massive Photonics, whose leadership is central to our goal of enabling scientists solve critical research questions using DNA-PAINT technologies.

#SMLM #DNAPAINT #Microscopy #DNAorigami
July 23, 2025 at 7:23 AM
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Our scientists have stamina!!! 💪🏃‍♀️A big congrats to our team for crushing the B2Run here in Munich! 🎉

#gemeinsamaktiv #stark
July 18, 2025 at 9:23 AM
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🚨 𝗡𝗲𝘄 𝗗𝗡𝗔-𝗣𝗔𝗜𝗡𝗧 𝗞𝗶𝘁 𝗗𝗿𝗼𝗽! 🚨
Ready to image 𝗛𝘂𝗺𝗮𝗻 𝗜𝗴𝗚𝘀 at the nanoscale?
🔗Click here: bit.ly/3GOvpUu
Compatible with all our DNA-PAINT kits for seamless multiplexing.

#DNAPAINT #SMLM #Microscopy #MassivePhotonics
July 17, 2025 at 8:13 AM
massivephotonics.bsky.social
🚀𝗔𝗹𝗿𝗲𝗮𝗱𝘆 𝘄𝗼𝗿𝗸𝗶𝗻𝗴 𝘄𝗶𝘁𝗵 𝗽𝗿𝗼𝘁𝗲𝗶𝗻-𝘁𝗮𝗴𝗴𝗲𝗱 𝗰𝗲𝗹𝗹 𝗹𝗶𝗻𝗲𝘀? Take your imaging to the nanoscale with our 𝗽𝗹𝘂𝗴-𝗮𝗻𝗱-𝗽𝗹𝗮𝘆 𝗗𝗡𝗔-𝗣𝗔𝗜𝗡𝗧 𝗸𝗶𝘁𝘀 - designed to fit seamlessly into your existing immunostaining workflows.

www.massive-photonics.com/product-cate...

#DNAPAINT #SuperResolution #FluorescentProteins #SMLM
Images created using our DNA-PAINT Kits for GFP, ALFA, mEOS, and RFP protein tag labeling. GFP - Nup96, ALFA - vimentin, mEOS - Tom20, RFP - EGFR. Credit for the beautiful ALFA-tag image goes to the Christophe Leterrier lab.
July 16, 2025 at 7:31 AM
massivephotonics.bsky.social
🔬 𝗕𝗲𝗵𝗶𝗻𝗱 𝘁𝗵𝗲 𝗕𝗶𝗻𝗱𝗲𝗿𝘀: 𝗠𝗲𝗲𝘁 𝗞𝗶𝗺𝗯𝗲𝗿𝗹𝘆 🔬

Ever wonder what actually goes on at Massive Photonics before you get your hands on one of our ready-to-use DNA-PAINT kits?

#MassivePhotonics #SuperResolution #SMLM #CellImaging #DNAPAINT
July 10, 2025 at 10:02 AM
massivephotonics.bsky.social
🚨 New Product Alert 🚨
Introducing a 𝗗𝗡𝗔-𝗣𝗔𝗜𝗡𝗧 𝗞𝗶𝘁 𝗳𝗼𝗿 𝗥𝗙𝗣-𝘁𝗮𝗴𝗴𝗲𝗱 𝗣𝗿𝗼𝘁𝗲𝗶𝗻𝘀!

𝗟𝗲𝗮𝗿𝗻 𝗺𝗼𝗿𝗲: www.massive-photonics.com/product-cate...

#SMLM #DNAPAINT #Microscopy #RFP #CellImaging #MassivePhotonics
July 8, 2025 at 8:04 AM
massivephotonics.bsky.social
🔬𝗕𝗲𝗵𝗶𝗻𝗱 𝘁𝗵𝗲 𝗕𝗶𝗻𝗱𝗲𝗿𝘀: 𝗠𝗲𝗲𝘁 𝗦𝗲𝗯𝗮𝘀𝘁𝗶𝗮𝗻🔬
Ever wonder what actually goes on at Massive Photonics before you get your hands on one of our ready-to-use DNA-PAINT kits?

We’re shining the spotlight on Dr. Sebastian Strauss, our CTO. (1/5)

#MassivePhotonics #SuperResolution #SMLM #CellImaging
July 7, 2025 at 8:27 AM
massivephotonics.bsky.social
𝗜𝗻𝘁𝗿𝗼𝗱𝘂𝗰𝗶𝗻𝗴 𝗼𝘂𝗿 𝗺𝗼𝘀𝘁 𝘃𝗲𝗿𝘀𝗮𝘁𝗶𝗹𝗲 𝗗𝗡𝗔-𝗣𝗔𝗜𝗡𝗧 𝗺𝘂𝗹𝘁𝗶𝗽𝗹𝗲𝘅𝗶𝗻𝗴 𝗸𝗶𝘁 𝘆𝗲𝘁! MASSIVE-sdAB-FAST 1 - 6-Plex kits enable users to create a 𝗰𝘂𝘀𝘁𝗼𝗺𝗶𝘇𝗲𝗱 𝗸𝗶𝘁 𝗳𝗼𝗿 𝟭 – 𝟲 𝘁𝗮𝗿𝗴𝗲𝘁 𝗶𝗺𝗮𝗴𝗶𝗻𝗴!

#DNAPAINT #SuperResolution #Microscopy #MassivePhotonics #PreMixing #SMLM
Magenta: Tubulin, White: Vimentin, Cyan: Tom20, Blue: Lamp1, Orange: H3k9ac
June 27, 2025 at 8:24 AM
massivephotonics.bsky.social
𝗥𝗲𝗮𝗱𝘆 𝗳𝗼𝗿 𝟯-𝘁𝗮𝗿𝗴𝗲𝘁 𝗗𝗡𝗔-𝗣𝗔𝗜𝗡𝗧 𝗶𝗺𝗮𝗴𝗶𝗻𝗴?
Meet Massive-AB 3-PLEX, a comprehensive kit for 3-target multiplexing.

#DNAPAINT #SMLM #MINFLUX #microscopy #superresolution

(1/3)
June 11, 2025 at 1:26 PM
massivephotonics.bsky.social
🔬 𝗖𝘂𝗿𝗶𝗼𝘂𝘀 𝗮𝗯𝗼𝘂𝘁 #𝗗𝗡𝗔𝗣𝗔𝗜𝗡𝗧 𝘀𝘂𝗽𝗲𝗿-𝗿𝗲𝘀𝗼𝗹𝘂𝘁𝗶𝗼𝗻 𝗺𝗶𝗰𝗿𝗼𝘀𝗰𝗼𝗽𝘆 𝗯𝘂𝘁 𝗱𝗼𝗻’𝘁 𝘄𝗮𝗻𝘁 𝘁𝗼 𝗽𝗿𝗲𝗽 𝗮 𝘀𝗮𝗺𝗽𝗹𝗲? Need a 𝗿𝗲𝗹𝗶𝗮𝗯𝗹𝗲, 𝗵𝗶𝗴𝗵-𝗾𝘂𝗮𝗹𝗶𝘁𝘆 #𝗦𝗠𝗟𝗠 𝗱𝗲𝗺𝗼 𝘀𝗹𝗶𝗱𝗲 for your next workshop or training session?

⭐ Meet our ready-to-image Stable Cell slide for DNA-PAINT microscopy!

www.massive-photonics.com/product-cate...
DNA-PAINT image of a 4 month old MASSIVE-CELLS 2-PLEX slide. Vimentin in cyan, mitochondria in orange.
May 21, 2025 at 2:03 PM
massivephotonics.bsky.social
🔬 𝗕𝗲𝗵𝗶𝗻𝗱 𝘁𝗵𝗲 𝗕𝗶𝗻𝗱𝗲𝗿𝘀: 𝗠𝗲𝗲𝘁 𝗟𝘂𝗰𝗶𝗮 🔬

Ever wonder what actually goes on at Massive Photonics before you get your hands on one of our ready-to-use DNA-PAINT kits?

#MassivePhotonics #SuperResolution #SMLM #CellImaging #FluorescenceMicroscopy #DNAPAINT

(1/4)
May 19, 2025 at 8:15 AM