Martin Pacesa
@martinpacesa.bsky.social
Structural biologist working on 🖥️ protein design, machine learning🤖, crystallography💎, and cryoEM🔬. Avid weirdness connoisseur 🎩
That is amazing Dawid!
November 24, 2025 at 6:37 AM
That is amazing Dawid!
Reposted by Martin Pacesa
ProteinCHAOS runs entirely in the browser and lets you choose how to visualize your protein structures.
It supports PDB files from the PDB and AlphaFold servers and offers several visual themes so you can "paint" abstract art with protein traces. I hope it helps you create some interesting images!
It supports PDB files from the PDB and AlphaFold servers and offers several visual themes so you can "paint" abstract art with protein traces. I hope it helps you create some interesting images!
November 23, 2025 at 11:18 PM
ProteinCHAOS runs entirely in the browser and lets you choose how to visualize your protein structures.
It supports PDB files from the PDB and AlphaFold servers and offers several visual themes so you can "paint" abstract art with protein traces. I hope it helps you create some interesting images!
It supports PDB files from the PDB and AlphaFold servers and offers several visual themes so you can "paint" abstract art with protein traces. I hope it helps you create some interesting images!
Of course this was not alone and it’s all the thanks to the work done in Bruno Correia’s and Martin Jinek’s lab with some amazing and supportive people. Super excited to transfer all of those experiences to my lab at the University of Zurich
November 14, 2025 at 12:20 PM
Of course this was not alone and it’s all the thanks to the work done in Bruno Correia’s and Martin Jinek’s lab with some amazing and supportive people. Super excited to transfer all of those experiences to my lab at the University of Zurich
The award was primarily on the development of #BindCraft, membrane protein solubilisation, and structural characterization and engineering of gene editors.
November 14, 2025 at 12:20 PM
The award was primarily on the development of #BindCraft, membrane protein solubilisation, and structural characterization and engineering of gene editors.
Cryowriter is the bomb man
November 3, 2025 at 9:29 PM
Cryowriter is the bomb man
In addition to that, we had the amazing opportunity to speak with Lennart in Zacatecas along the whole Mexican biochemistry community, such an incredible venue and great community of scientists. Thanks to Jose A. Farias Rico for inviting us!!!
October 28, 2025 at 11:53 PM
In addition to that, we had the amazing opportunity to speak with Lennart in Zacatecas along the whole Mexican biochemistry community, such an incredible venue and great community of scientists. Thanks to Jose A. Farias Rico for inviting us!!!
Great job! How does it compare in terms of speed?
October 28, 2025 at 11:12 PM
Great job! How does it compare in terms of speed?
We wrote up recommendations on input processing and target site selection in the supplement of the published paper, including best practices if no designs are passing. Of course it is a matter of experience and over time one gets a better sense of what a possible target is (not all are of course)
October 18, 2025 at 8:35 AM
We wrote up recommendations on input processing and target site selection in the supplement of the published paper, including best practices if no designs are passing. Of course it is a matter of experience and over time one gets a better sense of what a possible target is (not all are of course)
I should mention that the targets in the paper were not cherry picked, there weren’t 50 targets that didnt work and we did not include them. In fact, we did most of those targets specifically, because they failed for us with other methods. Did you try only peptides or also miniproteins?
October 18, 2025 at 8:31 AM
I should mention that the targets in the paper were not cherry picked, there weren’t 50 targets that didnt work and we did not include them. In fact, we did most of those targets specifically, because they failed for us with other methods. Did you try only peptides or also miniproteins?
Excellent article Claus! I totally agree with you, not all biological problems are the same and some are harder than others. And of course BindCraft has limitations stemming from AlphaFold, more specifically AlphaFold monomer filtering in the last step.
October 18, 2025 at 8:31 AM
Excellent article Claus! I totally agree with you, not all biological problems are the same and some are harder than others. And of course BindCraft has limitations stemming from AlphaFold, more specifically AlphaFold monomer filtering in the last step.