Marc Veldhoen
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marcveld.bsky.social
Marc Veldhoen
@marcveld.bsky.social
Professor of Immunology 🇳🇱 🇬🇧
Lisbon, 🇵🇹

#Immunology
Time for Science, not silence

https://scholar.google.co.uk/citations?user=7vG1jLIAAAAJ&hl=en

https://orcid.org/0000-0002-1478-9562

threads.net/@marc_veld

mastodon.online/@marc_veld
Reposted by Marc Veldhoen
Facts aren’t cruelty. It’s the first step toward recovery. And those fighting misinformation aren’t your enemies, they’re the reason real progress against #LongCovid is possible. But only with funding, good and defined cohorts, appropriate methods, and with real solid data.
10/10
October 20, 2025 at 4:45 PM
Rhabdomyolysis
November 23, 2025 at 8:46 PM
"Oxidative stress". How was that determined? It is only used in "alternative medicine".
November 23, 2025 at 8:30 PM
This should not be used by pregnant women and those breastfeeding (fetal growth issues). It should not be used by young children (under 8; teeth and bone issues).

Please do not use this unless prescribed by a qualified physician!
6/6
November 23, 2025 at 8:04 PM
If you have been prescribed 200mg/day as the poster claims, this is a high dose. This is not for anti-inflammatory properties, but against severe bacterial infections!

Importantly, this can result in side effects: Nausea, vomiting, diarrhoea and fungal infections.
5/6
November 23, 2025 at 8:04 PM
The molecular mechanism is complex. Doxycycline can capture calcium and zinc, thereby reducing the activity of enzymes using these cations. It may also reduce a key signalling pathway, resulting in cytokine and chemokine production.
4/6
November 23, 2025 at 8:04 PM
At sub-antimicrobial concentrations (~40mg/day), doxycycline can work as an anti-inflammatory. It can inhibit the production of several immune mediators, e.g. some cytokines and chemokines. This is particularly applied to skin problems, but also to others.

How?
3/6
November 23, 2025 at 8:04 PM
thereby allowing your immune system to gain the upper hand and clear the bacteria (100mg/day). But it doesn´t leave our own protein-generating machinery entirely alone. Although at higher concentrations, it can reduce your cells from multiplying and performing their function.
2/6
November 23, 2025 at 8:04 PM
It is a complex I inhibitor. Therefore it inhibits cell metabolism, also reducing viral replication. But it is not specific, affecting all cells (also immune cells). Some maybe more sensitive than others.
November 23, 2025 at 2:11 PM