Manal Mehta
@manalmehta.bsky.social
Tweeting in my personal capacity.
"Put simply, a significant share of the US’s “booming” economy is generated by sickness. Inefficiencies in its healthcare system may also prop up US GDP by sustaining high levels of costly healthcare-related expenditure"
January 15, 2025 at 1:42 PM
"Put simply, a significant share of the US’s “booming” economy is generated by sickness. Inefficiencies in its healthcare system may also prop up US GDP by sustaining high levels of costly healthcare-related expenditure"
"48 per cent of respondents asked generative AI chatbots such as ChatGPT, Gemini, Copilot and Claude health-focused questions." www.ft.com/content/c41b...
December 11, 2024 at 3:35 PM
"48 per cent of respondents asked generative AI chatbots such as ChatGPT, Gemini, Copilot and Claude health-focused questions." www.ft.com/content/c41b...
What do you think of Setd1a as a target for Sangamo, @urnov.bsky.social?
“They estimated that a mutation on a single gene, called Setd1a, raised the risk 20-fold.”
www.wsj.com/health/healt...
“They estimated that a mutation on a single gene, called Setd1a, raised the risk 20-fold.”
www.wsj.com/health/healt...
November 27, 2024 at 8:05 PM
What do you think of Setd1a as a target for Sangamo, @urnov.bsky.social?
“They estimated that a mutation on a single gene, called Setd1a, raised the risk 20-fold.”
www.wsj.com/health/healt...
“They estimated that a mutation on a single gene, called Setd1a, raised the risk 20-fold.”
www.wsj.com/health/healt...
I enjoyed @anjahuja.bsky.social's piece in the FT on the implications of RFK Jr. as the face of Science in the Trump administration. Given that RFK's running mate, Nicole Shanahan, was a patent attorney, does anyone have more insight into the highlighted bits below... www.ft.com/content/3226...
November 21, 2024 at 12:07 PM
I enjoyed @anjahuja.bsky.social's piece in the FT on the implications of RFK Jr. as the face of Science in the Trump administration. Given that RFK's running mate, Nicole Shanahan, was a patent attorney, does anyone have more insight into the highlighted bits below... www.ft.com/content/3226...
Interesting (& scary) RFP from DARPA: Looking to fund the development of inhibitors "to counteract the accidental or intentional misuse of gene editing technologies." Seems right up your alley, @urnov.bsky.social sam.gov/opp/d04ec5d6...
November 21, 2024 at 1:50 AM
Interesting (& scary) RFP from DARPA: Looking to fund the development of inhibitors "to counteract the accidental or intentional misuse of gene editing technologies." Seems right up your alley, @urnov.bsky.social sam.gov/opp/d04ec5d6...
From March 2024:
Navega using Charles River for AAV9 production for their Nav 1.7 Phase 1 trial.
ir.criver.com/news-release...
Navega using Charles River for AAV9 production for their Nav 1.7 Phase 1 trial.
ir.criver.com/news-release...
November 20, 2024 at 2:05 AM
From March 2024:
Navega using Charles River for AAV9 production for their Nav 1.7 Phase 1 trial.
ir.criver.com/news-release...
Navega using Charles River for AAV9 production for their Nav 1.7 Phase 1 trial.
ir.criver.com/news-release...
Even just STAC BBB seems to open the door to quite a number of other monogenic diseases.
November 15, 2024 at 8:05 PM
Even just STAC BBB seems to open the door to quite a number of other monogenic diseases.
Sangamo claims to have solved the manufacturing challenge. From: investor.sangamo.com/static-files...
"We have successfully manufactured up to 50-liter scale, and further scale up to 500-liter is in progress"
"We have successfully manufactured up to 50-liter scale, and further scale up to 500-liter is in progress"
November 15, 2024 at 5:13 PM
Sangamo claims to have solved the manufacturing challenge. From: investor.sangamo.com/static-files...
"We have successfully manufactured up to 50-liter scale, and further scale up to 500-liter is in progress"
"We have successfully manufactured up to 50-liter scale, and further scale up to 500-liter is in progress"
Bosch in China using robots to replace workers in manufacturing car parts. 30 robots replaces 50 workers with only 2 weeks training! www.ft.com/content/dc7e...
November 14, 2024 at 12:03 PM
Bosch in China using robots to replace workers in manufacturing car parts. 30 robots replaces 50 workers with only 2 weeks training! www.ft.com/content/dc7e...
If Sangamo's novel STAC-BBB Capsid is successful, isn't this one of the most exciting and extraordinary opportunities in genomic medicine? The pipeline is truly limitless. Initial Prion data looks promising - how can that be replicated across other monogenic diseases? cc: @urnov.bsky.social
November 13, 2024 at 6:33 PM
If Sangamo's novel STAC-BBB Capsid is successful, isn't this one of the most exciting and extraordinary opportunities in genomic medicine? The pipeline is truly limitless. Initial Prion data looks promising - how can that be replicated across other monogenic diseases? cc: @urnov.bsky.social
November 19, 2024 at 3:25 PM
So at what point are we allowed to talk about the enormous potential of $SGMO's epigenetic regulation capabilities and assigning a value of more than $0 to it? The potential here is absolutely mind boggling if it works as advertised. cc: @sandymacrae23 @BarryGreene
November 19, 2024 at 3:24 PM
So at what point are we allowed to talk about the enormous potential of $SGMO's epigenetic regulation capabilities and assigning a value of more than $0 to it? The potential here is absolutely mind boggling if it works as advertised. cc: @sandymacrae23 @BarryGreene
hi @JeremiasPrassl & @veenadubal - very interesting potential development in #Mexico, re: algorithmic management. $UBER $LYFT
"Companies must also include a description of how their algorithms work in labor contracts."
cc: @AOC @ewarren @LorenaSGonzalez
"Companies must also include a description of how their algorithms work in labor contracts."
cc: @AOC @ewarren @LorenaSGonzalez
November 19, 2024 at 3:24 PM
hi @JeremiasPrassl & @veenadubal - very interesting potential development in #Mexico, re: algorithmic management. $UBER $LYFT
"Companies must also include a description of how their algorithms work in labor contracts."
cc: @AOC @ewarren @LorenaSGonzalez
"Companies must also include a description of how their algorithms work in labor contracts."
cc: @AOC @ewarren @LorenaSGonzalez
STAMP protocol from @hoheyn could be the death knell for 10x Genomics $TXG.
“cost per cell is approximately one half of a cent, and the method does not require additional analysis by sequencing”
@OmicsOmicsBlog @AlbertVilella @LGMartelotto @MollyminHe
“cost per cell is approximately one half of a cent, and the method does not require additional analysis by sequencing”
@OmicsOmicsBlog @AlbertVilella @LGMartelotto @MollyminHe
November 19, 2024 at 3:24 PM
STAMP protocol from @hoheyn could be the death knell for 10x Genomics $TXG.
“cost per cell is approximately one half of a cent, and the method does not require additional analysis by sequencing”
@OmicsOmicsBlog @AlbertVilella @LGMartelotto @MollyminHe
“cost per cell is approximately one half of a cent, and the method does not require additional analysis by sequencing”
@OmicsOmicsBlog @AlbertVilella @LGMartelotto @MollyminHe
💯 agree w/ @SirPeterLampl. Structural inequality is destroying the American Dream.
"This disparity chokes off social mobility. And growing disillusionment with the undelivered promise of material improvement feeds into a tussle over the very foundations of US society."
"This disparity chokes off social mobility. And growing disillusionment with the undelivered promise of material improvement feeds into a tussle over the very foundations of US society."
November 19, 2024 at 3:24 PM
💯 agree w/ @SirPeterLampl. Structural inequality is destroying the American Dream.
"This disparity chokes off social mobility. And growing disillusionment with the undelivered promise of material improvement feeds into a tussle over the very foundations of US society."
"This disparity chokes off social mobility. And growing disillusionment with the undelivered promise of material improvement feeds into a tussle over the very foundations of US society."
$70/day in tax free income: "Staff are given daily allowances of $20 for breakfast, $25 for lunch & $25 for dinner, with meal credits issued in $25 increments."
Teacher or Firefighter pays for meals w/ after tax $$'s but $400k/year tech employees get $70 daily tax free! @AOC
Teacher or Firefighter pays for meals w/ after tax $$'s but $400k/year tech employees get $70 daily tax free! @AOC
November 19, 2024 at 3:24 PM
$70/day in tax free income: "Staff are given daily allowances of $20 for breakfast, $25 for lunch & $25 for dinner, with meal credits issued in $25 increments."
Teacher or Firefighter pays for meals w/ after tax $$'s but $400k/year tech employees get $70 daily tax free! @AOC
Teacher or Firefighter pays for meals w/ after tax $$'s but $400k/year tech employees get $70 daily tax free! @AOC
Isn't this exactly what #KamalaHarris has been saying? $MCD "alleges that Cargill, JBS, National Beef & Tyson together control up to 85% of market-ready cattle & are working together to hold down...the total supply to increase their profits." cc: @matthewstoller
November 19, 2024 at 3:24 PM
Isn't this exactly what #KamalaHarris has been saying? $MCD "alleges that Cargill, JBS, National Beef & Tyson together control up to 85% of market-ready cattle & are working together to hold down...the total supply to increase their profits." cc: @matthewstoller
Ouch $TXG … still got a long ways to go in my opinion. Sub $1bn market cap … another 50%+ drop coming.
November 19, 2024 at 3:23 PM
Ouch $TXG … still got a long ways to go in my opinion. Sub $1bn market cap … another 50%+ drop coming.
Armonica - yet another sequencing startup - that has raised $7mm & in midst of a $12mm series A. Heard of them before, @OmicsOmicsBlog @alexgdickinson @AlbertVilella? cc: @MollyminHe
Armonica's deck:
Armonica's deck:
November 19, 2024 at 3:23 PM
Armonica - yet another sequencing startup - that has raised $7mm & in midst of a $12mm series A. Heard of them before, @OmicsOmicsBlog @alexgdickinson @AlbertVilella? cc: @MollyminHe
Armonica's deck:
Armonica's deck:
Of course Netanyahu will continue to escalate to provoke Iran into a forceful response that leaves 🇺🇸 with no choice. Smarter choice would be for #Iran to de-escalate till after the election and if #Trump loses, #Netanyahu will be significantly weakened.
November 19, 2024 at 3:23 PM
Of course Netanyahu will continue to escalate to provoke Iran into a forceful response that leaves 🇺🇸 with no choice. Smarter choice would be for #Iran to de-escalate till after the election and if #Trump loses, #Netanyahu will be significantly weakened.
Dear @Surgeon_General we need an American (gun free) version of fællesspisning to combat the pandemic of loneliness. Would be amazing if the government could subsidize this in communities across America. Take a chapter from the Sikh Gurudwaras.
November 19, 2024 at 3:23 PM
Dear @Surgeon_General we need an American (gun free) version of fællesspisning to combat the pandemic of loneliness. Would be amazing if the government could subsidize this in communities across America. Take a chapter from the Sikh Gurudwaras.
We are mortgaging our children's futures to power #AI. Shouldn't the tech giants be mandated to offset carbon emissions as part of an aggressive expansion of AI? $MSFT $GOOG $META
November 19, 2024 at 3:23 PM
We are mortgaging our children's futures to power #AI. Shouldn't the tech giants be mandated to offset carbon emissions as part of an aggressive expansion of AI? $MSFT $GOOG $META
Yup, let’s keep scapegoating the immigrants. “More than 80 percent of the people sentenced for fentanyl trafficking at the southern border are U.S. citizens, federal data shows.”
November 19, 2024 at 3:22 PM
Yup, let’s keep scapegoating the immigrants. “More than 80 percent of the people sentenced for fentanyl trafficking at the southern border are U.S. citizens, federal data shows.”
November 19, 2024 at 3:22 PM