Mackinder Lab
mackinderlab.bsky.social
Mackinder Lab
@mackinderlab.bsky.social
Molecular basis of global carbon fixation. Algal tool development. Pyrenoids. LLPS.
Reposted by Mackinder Lab
Check out this cool thread on the latest preprint by Gaurav Kumar, @james-r-barrett.bsky.social, @phaips.vd.st from our lab and colleagues, dissecting the physics of Rubisco condensates!

You're in for some stunning #cryoET of the pyrenoid - in Chlamy, of course 😉

Congrats to all involved!
How does molecular valency shape condensate assembly and function? We used the CO2-fixing organelle in algae—the pyrenoid—to find out… 🧵

Preprint here!:
www.biorxiv.org/content/10.6...

@cellarchlab.com @phaips.vd.st @biologyatyork.bsky.social
#Rubisco #PhaseSeparation #Condensates #Pyrenoid
January 30, 2026 at 3:54 PM
Reposted by Mackinder Lab
Check this new study on carbon concentration mechanisms!

See how the pyrenoid changes by modifying Rubisco linkers in our favorite alga, Chlamy 💚!

My desk mate @phaips.vd.st spent a lot of time collecting & carefully analyzing these beautiful tomograms 🔬.

Congrats to all the authors!
How does molecular valency shape condensate assembly and function? We used the CO2-fixing organelle in algae—the pyrenoid—to find out… 🧵

Preprint here!:
www.biorxiv.org/content/10.6...

@cellarchlab.com @phaips.vd.st @biologyatyork.bsky.social
#Rubisco #PhaseSeparation #Condensates #Pyrenoid
January 30, 2026 at 7:40 PM
Reposted by Mackinder Lab
That is a really beautiful poster!🤩 🧪

Inside the Pyrenoid: How Multivalency Shapes Rubisco Organization and CO2 Fixation
www.biorxiv.org/content/10.6...
Lastly, if you prefer to see this as a poster, you can find that here:
james-r-barrett.github.io/presentation...
January 30, 2026 at 4:27 PM
Reposted by Mackinder Lab
You like #LLPS? #TeamTomo? #Rubisco? Check out our latest preprint!

What a great collaboration this has been!
How does molecular valency shape condensate assembly and function? We used the CO2-fixing organelle in algae—the pyrenoid—to find out… 🧵

Preprint here!:
www.biorxiv.org/content/10.6...

@cellarchlab.com @phaips.vd.st @biologyatyork.bsky.social
#Rubisco #PhaseSeparation #Condensates #Pyrenoid
January 30, 2026 at 3:38 PM
Reposted by Mackinder Lab
How does molecular valency shape condensate assembly and function? We used the CO2-fixing organelle in algae—the pyrenoid—to find out… 🧵

Preprint here!:
www.biorxiv.org/content/10.6...

@cellarchlab.com @phaips.vd.st @biologyatyork.bsky.social
#Rubisco #PhaseSeparation #Condensates #Pyrenoid
January 30, 2026 at 3:21 PM