Luca Pinello
lucapinello.bsky.social
Luca Pinello
@lucapinello.bsky.social
Computational methods for epigenetic, CRISPR genome editing and single-cell genomics. Associate Professor at MGH / Harvard Medical School. http://pinellolab.org
Applications are open NOW! Review starts December 22, so don't wait.
Apply here: academicjobsonline.org/ajo/jobs/30714
Questions? → [email protected]
Know someone perfect for this? Please RT and tag them! Let's help spread the word about this opportunity 🚀
Broad Institute of MIT and Harvard, Eric and Wendy Schmidt Center
Job #AJO30714, Postdoctoral Associate, Eric and Wendy Schmidt Center, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, US
academicjobsonline.org
October 22, 2025 at 2:50 AM
What makes this special:
1. YOU choose your mentors (both computational & biomedical)
2. Focus on mathematical foundations, not just applications
2. Ask "why do these algorithms work for biology?" not just "how"
3. Bridge theory ↔️ practice in ways that matter for human health
October 22, 2025 at 2:50 AM
What they're looking for:
✅ Strong background in ML, statistics, or applied math
✅ Drive to push biomedical research frontiers
✅ Computational/theoretical method development skills
Biology experience? Helpful but NOT required! They value diverse perspectives.
October 22, 2025 at 2:50 AM
The mission: Create the theoretical & algorithmic foundations to understand the programs of life across scales. You'll choose mentors from faculty across
@broadinstitute.org, @mit.edu and @harvard.edu and collaborate across these amazing institutions.
October 22, 2025 at 2:50 AM
@zainmunirpatel.bsky.social will also present this afternoon 2.30 to 4.30
Poster 4022W. Systematic benchmarking of computational methods for SVG detection. #spatial #ASHG2025
October 15, 2025 at 4:40 PM
📅OCT 17 | 2:30-4:30 PM | Poster 5057F
Jayoung Ryu ( @jykr.bsky.social ) presents "SIMBA+: Dissecting genetic variant function through single-cell multiomics integration"
Exciting multiomics integration work! #SingleCell #Multiomics #VariantInterpretation #ASHG2025
October 15, 2025 at 1:41 PM
📅 OCT 16 | 2:30-4:30 PM | Poster 6020T
I'll be at my poster: "CRISPRlungo: Accurate Quantification of Genome Editing Events from Long Reads"
Come chat about long-read sequencing & CRISPR! #GenomeEditing #LongReads #ASHG2025
October 15, 2025 at 1:41 PM
📅 OCT 16 | 10:45-11:00 AM | Room 205ABC
Basheer Becerra presents "Multi-modal functional mapping of non-coding sequences regulating fetal hemoglobin"
Exciting work on therapeutic targets! #FetalHemoglobin #ASHG2025
October 15, 2025 at 1:41 PM
Zhijian Li ( @zhijianli.bsky.social )presents "Cell2net: A Deep Learning Framework to Decode Genotype-Specific Gene Regulatory Networks from Single-Cell Multi-Omics"
#DeepLearning #GeneRegulation #ASHG2025
October 15, 2025 at 1:41 PM
📅 OCT 15 | 11:00-11:15 AM | Room 258ABC
Logan Blaine presents "PerTurbo: A scalable Bayesian framework for whole-transcriptome differential expression analysis & optimal design of single-cell CRISPR screens"
#CRISPRscreen #SingleCell #ASHG2025
October 15, 2025 at 1:41 PM
It was indeed fantastic! Thank you so much to all the organizers for supporting this community. 🙏
July 25, 2025 at 7:37 AM
This changed how I write. No context switching, no copying - just select, shortcut, done!
👉 github.com/lucapinello/claude-text-editor
Feedback welcome! Thanks @anthropic.com for MCP, Claude Code and Claude Desktop!

What will you build on your next rainy afternoon? 🌧️✨
GitHub - lucapinello/claude-text-editor: MCP-powered text editing system that integrates Claude
MCP-powered text editing system that integrates Claude - lucapinello/claude-text-editor
github.com
June 8, 2025 at 12:58 AM
Why it rocks:

File-based (no timeouts!)
Desktop notifications
Auto-clipboard magic
Works with Claude Desktop
Open source (MIT)

Built for macOS 14+ 🍎
June 8, 2025 at 12:58 AM
Want Claude to channel Hemingway? Add emojis? Write formally?
Edit ~/.claude_text_editor/claude_prompt.txt
Make Claude YOUR personalized writing assistant! ✍️
The possibilities are endless...
June 8, 2025 at 12:58 AM
Love the terminal? Add this to ~/.zshrc:
ce() {
if [ $# -eq 0 ]; then
pbpaste | ~/claude-text-editor/claude_text_client.py
else
printf '%s\n' "$*" | ~/claude-text-editor/claude_text_client.py
fi
}
Now: ce Fix this sentence that have bad grammer ✨
June 8, 2025 at 12:58 AM
Here's the killer feature...
No text selected? It auto-grabs your clipboard!
Already copied something? Just hit the shortcut. Claude polishes it instantly.
Smart defaults FTW! 🧠
June 8, 2025 at 12:58 AM