Matthias Spiller-Becker
@lovin-chromatin.bsky.social
Father & Husband | Family | Epigenetics & Chromatin | Active Motif team member | Virtual Chromatin Club Pioneer | Equality&Tolerance&Empathy | Foosball & Board Game enthusiast | Oh...and let's not forget to find a CURE for stupid people!
Pinned
I think that in those times, this is a proper first post on this platform, for me.
Reposted by Matthias Spiller-Becker
This October I’m drawing 1 molecule a day inspired by proteins in pdb @rcsbpdb.bsky.social
Day 20/31
Prompt RIVALS
Pdb: 8V27 & 8G6S
Two rival histone modifications on a nucleosome. Ubiquitination of H2BK120 activates genes while H2AK119 represses them.
Next: BLAST
Suggestions?
Day 20/31
Prompt RIVALS
Pdb: 8V27 & 8G6S
Two rival histone modifications on a nucleosome. Ubiquitination of H2BK120 activates genes while H2AK119 represses them.
Next: BLAST
Suggestions?
November 4, 2025 at 5:41 PM
Reposted by Matthias Spiller-Becker
Happy to report that the first part of my PhD work is published! Thank you to everyone involved!
Happy to share our latest publication, in which we show that the arrangement of nucleosomes around CTCF sites contributes to higher-order organisation of chromatin into TADs: www.embopress.org/doi/full/10....
October 27, 2025 at 12:35 PM
Happy to report that the first part of my PhD work is published! Thank you to everyone involved!
Reposted by Matthias Spiller-Becker
California, this November 4th, the whole country is counting on you.
Prop 50 puts our elections back on a level playing field, preserves independent redistricting over the long term, and lets the people decide.
So return your ballot today. Vote yes on 50.
Prop 50 puts our elections back on a level playing field, preserves independent redistricting over the long term, and lets the people decide.
So return your ballot today. Vote yes on 50.
October 14, 2025 at 5:04 PM
California, this November 4th, the whole country is counting on you.
Prop 50 puts our elections back on a level playing field, preserves independent redistricting over the long term, and lets the people decide.
So return your ballot today. Vote yes on 50.
Prop 50 puts our elections back on a level playing field, preserves independent redistricting over the long term, and lets the people decide.
So return your ballot today. Vote yes on 50.
Reposted by Matthias Spiller-Becker
We have people in power making broad claims around certain drugs and autism that have been continuously disproven.
September 25, 2025 at 2:02 PM
We have people in power making broad claims around certain drugs and autism that have been continuously disproven.
Reposted by Matthias Spiller-Becker
Amazing 2. day at the GfG ‘Epigenetics & Chromatin’ symposium. Fantastic flash talks, a great first poster session and many memorable talks: among others @erhardtlab.bsky.social, @rodvilla.bsky.social, @thebraunlab.bsky.social, @flurylab.bsky.social, Ehrenhofer-Murray, Liefke, Heun, Imhof & Brehm.
September 25, 2025 at 9:56 PM
Amazing 2. day at the GfG ‘Epigenetics & Chromatin’ symposium. Fantastic flash talks, a great first poster session and many memorable talks: among others @erhardtlab.bsky.social, @rodvilla.bsky.social, @thebraunlab.bsky.social, @flurylab.bsky.social, Ehrenhofer-Murray, Liefke, Heun, Imhof & Brehm.
More chromatin expertise for Freiburg : )
Congratulations Simon and Team Elsässer lab!
Congratulations Simon and Team Elsässer lab!
Today I have been officially appointed to full Professor at @uni-freiburg.de 🎉.
September 19, 2025 at 10:54 AM
More chromatin expertise for Freiburg : )
Congratulations Simon and Team Elsässer lab!
Congratulations Simon and Team Elsässer lab!
Reposted by Matthias Spiller-Becker
Our democracy is not self-executing. It depends on us all as citizens, regardless of our political affiliations, to stand up and fight for the core values that have made this country the envy of the world.
September 17, 2025 at 8:04 PM
Our democracy is not self-executing. It depends on us all as citizens, regardless of our political affiliations, to stand up and fight for the core values that have made this country the envy of the world.
Reposted by Matthias Spiller-Becker
We are excited to officially welcome a new group leader at the MPI-IE in #Freiburg. 🎉
Dr Juliane Glaser 🥳 – she studies epigenetic mechanisms of embryonic development, with a focus on transposable elements. 👉 Interview: www.ie-freiburg.mpg.de/6043545/2025...
Welcome, @julianeg.bsky.social!
Dr Juliane Glaser 🥳 – she studies epigenetic mechanisms of embryonic development, with a focus on transposable elements. 👉 Interview: www.ie-freiburg.mpg.de/6043545/2025...
Welcome, @julianeg.bsky.social!
June 25, 2025 at 9:05 AM
We are excited to officially welcome a new group leader at the MPI-IE in #Freiburg. 🎉
Dr Juliane Glaser 🥳 – she studies epigenetic mechanisms of embryonic development, with a focus on transposable elements. 👉 Interview: www.ie-freiburg.mpg.de/6043545/2025...
Welcome, @julianeg.bsky.social!
Dr Juliane Glaser 🥳 – she studies epigenetic mechanisms of embryonic development, with a focus on transposable elements. 👉 Interview: www.ie-freiburg.mpg.de/6043545/2025...
Welcome, @julianeg.bsky.social!
Reposted by Matthias Spiller-Becker
It was a privilege to be part of the Allis lab. Dave fostered an environment of rigor, curiosity, and kindness- his impact lives on in the many he mentored. Grateful to reconnect at Rockefeller with this extraordinary group. Thank you to the organizers for an inspiring symposium.
June 16, 2025 at 3:42 PM
It was a privilege to be part of the Allis lab. Dave fostered an environment of rigor, curiosity, and kindness- his impact lives on in the many he mentored. Grateful to reconnect at Rockefeller with this extraordinary group. Thank you to the organizers for an inspiring symposium.
Real Mon Mothma vibes there!
Just with a different ending (so far).
Just with a different ending (so far).
SEN. PADILLA: “Saying I lunged is a lie, but that’s par for the course for this administration… I was behind the cameras listening, and at a certain point hearing Noem say they had to rescue LA from the Governor and Mayor was too much to take. So I raise my voice to ask a question.”
June 13, 2025 at 1:13 PM
Real Mon Mothma vibes there!
Just with a different ending (so far).
Just with a different ending (so far).
Reposted by Matthias Spiller-Becker
Off to the @activemotifusa.bsky.social #epigenetics seminar here at @newcastleuni.bsky.social @nucancer.bsky.social delivered by Field Application Scientist Dr Anne-Sophie AY-BERTHOMIEU (during MNase incubation for the #CUTRUN workshop 😎)
Let’s take a dive into the beauty of #epigenetics 🧬🧬
Let’s take a dive into the beauty of #epigenetics 🧬🧬
June 12, 2025 at 12:28 PM
Off to the @activemotifusa.bsky.social #epigenetics seminar here at @newcastleuni.bsky.social @nucancer.bsky.social delivered by Field Application Scientist Dr Anne-Sophie AY-BERTHOMIEU (during MNase incubation for the #CUTRUN workshop 😎)
Let’s take a dive into the beauty of #epigenetics 🧬🧬
Let’s take a dive into the beauty of #epigenetics 🧬🧬
Reposted by Matthias Spiller-Becker
🔬✨ Excited to share a major milestone from my PhD research at Institut Curie, where I am a first author in a recently published paper in Nature Communications!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
H3.3 deposition counteracts the replication-dependent enrichment of H3.1 at chromocenters in embryonic stem cells - Nature Communications
In mammals, two major non-centromeric histone H3 (H3.1/2 and H3.3) variants, display distinct nuclear distribution patterns across the genome and use distinct deposition pathways. Here the authors rev...
www.nature.com
June 4, 2025 at 4:46 AM
🔬✨ Excited to share a major milestone from my PhD research at Institut Curie, where I am a first author in a recently published paper in Nature Communications!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Absolutely worth the 5 min read!
Breaking a glass ceiling for little girls who dream of growing up to be a dingus lyz.substack.com/p/magic-scho...
Dingus of the Week: Pam Bondi
Stock market is down, measles are up
lyz.substack.com
May 9, 2025 at 12:46 PM
Absolutely worth the 5 min read!
Reposted by Matthias Spiller-Becker
👏 Congratulations to Dr. Stefan Dillinger - host of the Active Motif #Epigenetics #Podcast & Episode 150!!
Tune in and discover "The Stories Behind the Science" 🎙️ bit.ly/437eALC
#genomics #epigenetics #cancerresearch #ASCO25 #AAI25 #AACR25
Tune in and discover "The Stories Behind the Science" 🎙️ bit.ly/437eALC
#genomics #epigenetics #cancerresearch #ASCO25 #AAI25 #AACR25
May 8, 2025 at 3:45 PM
👏 Congratulations to Dr. Stefan Dillinger - host of the Active Motif #Epigenetics #Podcast & Episode 150!!
Tune in and discover "The Stories Behind the Science" 🎙️ bit.ly/437eALC
#genomics #epigenetics #cancerresearch #ASCO25 #AAI25 #AACR25
Tune in and discover "The Stories Behind the Science" 🎙️ bit.ly/437eALC
#genomics #epigenetics #cancerresearch #ASCO25 #AAI25 #AACR25
That Stephen Miller guy could have been cast for Andor Season 2.
Perfect Imperial Propaganda bullshit!
Perfect Imperial Propaganda bullshit!
Stephen Miller: "Children will be taught to love America. Children will be taught to be patriots. Children will be taught civic values for schools that want federal taxpayer funding ... we're gonna make sure these funds are not being used to promote communist ideology."
May 2, 2025 at 12:37 PM
That Stephen Miller guy could have been cast for Andor Season 2.
Perfect Imperial Propaganda bullshit!
Perfect Imperial Propaganda bullshit!
Reposted by Matthias Spiller-Becker
Do not forget:
🎉 Join us at the GfG Symposium "Epigenetics & Chromatin" in Giessen, Sept 24–26, 2025!
Great speakers, low fees, prizes for best poster & short talk, + free GfG membership for non-members.
Please RT!
Info and Registration: express.converia.de/frontend/ind...
🎉 Join us at the GfG Symposium "Epigenetics & Chromatin" in Giessen, Sept 24–26, 2025!
Great speakers, low fees, prizes for best poster & short talk, + free GfG membership for non-members.
Please RT!
Info and Registration: express.converia.de/frontend/ind...
April 23, 2025 at 10:14 AM
Do not forget:
🎉 Join us at the GfG Symposium "Epigenetics & Chromatin" in Giessen, Sept 24–26, 2025!
Great speakers, low fees, prizes for best poster & short talk, + free GfG membership for non-members.
Please RT!
Info and Registration: express.converia.de/frontend/ind...
🎉 Join us at the GfG Symposium "Epigenetics & Chromatin" in Giessen, Sept 24–26, 2025!
Great speakers, low fees, prizes for best poster & short talk, + free GfG membership for non-members.
Please RT!
Info and Registration: express.converia.de/frontend/ind...
Reposted by Matthias Spiller-Becker
Senator Chris Van Hollen is on his way to El Salvador to discuss bringing Kilmar Abrgeo Garcia back home.
April 16, 2025 at 11:13 AM
Senator Chris Van Hollen is on his way to El Salvador to discuss bringing Kilmar Abrgeo Garcia back home.
Reposted by Matthias Spiller-Becker
As we approach episode 150 of the Active Motif #Epigenetics #Podcast, our host Dr. Stefan Dillinger (right) shares this week's fun photo with our latest guest Dr. Boyan Bonev. Contact Stefan to get your seat at the mic! 🎙️
Catch the latest episodes ➡️ bit.ly/4gLeVbZ
#Epigenomics #Genomics
Catch the latest episodes ➡️ bit.ly/4gLeVbZ
#Epigenomics #Genomics
April 1, 2025 at 2:10 PM
As we approach episode 150 of the Active Motif #Epigenetics #Podcast, our host Dr. Stefan Dillinger (right) shares this week's fun photo with our latest guest Dr. Boyan Bonev. Contact Stefan to get your seat at the mic! 🎙️
Catch the latest episodes ➡️ bit.ly/4gLeVbZ
#Epigenomics #Genomics
Catch the latest episodes ➡️ bit.ly/4gLeVbZ
#Epigenomics #Genomics
Hey #cfDNA community!
What looks like "just another kind of beads" is actually really cool! All of you who regularly purify and analyse cfDNA from plasma or saliva: highly recommend to check out these beads!
What looks like "just another kind of beads" is actually really cool! All of you who regularly purify and analyse cfDNA from plasma or saliva: highly recommend to check out these beads!
March 28, 2025 at 8:07 AM
Hey #cfDNA community!
What looks like "just another kind of beads" is actually really cool! All of you who regularly purify and analyse cfDNA from plasma or saliva: highly recommend to check out these beads!
What looks like "just another kind of beads" is actually really cool! All of you who regularly purify and analyse cfDNA from plasma or saliva: highly recommend to check out these beads!
Reposted by Matthias Spiller-Becker
To quote the great Sally Field in Forrest Gump: 'stupid is as stupid does'
March 27, 2025 at 6:43 PM
To quote the great Sally Field in Forrest Gump: 'stupid is as stupid does'
Reposted by Matthias Spiller-Becker
A new antibiotic, found in soil samples collected from a lab technician’s garden, targets a broad range of pathogens -even drug resistant ones
➡️ www.nature.com/articles/d41...
➡️ www.nature.com/articles/s41...
#antibioticresistance #antimicrobials
➡️ www.nature.com/articles/d41...
➡️ www.nature.com/articles/s41...
#antibioticresistance #antimicrobials
A broad-spectrum lasso peptide antibiotic targeting the bacterial ribosome - Nature
A new lasso peptide antibiotic exhibits broad-spectrum activity against Gram-negative and Gram-positive bacteria by interfering with bacterial protein synthesis, is unaffected by common resistanc...
www.nature.com
March 28, 2025 at 7:11 AM
A new antibiotic, found in soil samples collected from a lab technician’s garden, targets a broad range of pathogens -even drug resistant ones
➡️ www.nature.com/articles/d41...
➡️ www.nature.com/articles/s41...
#antibioticresistance #antimicrobials
➡️ www.nature.com/articles/d41...
➡️ www.nature.com/articles/s41...
#antibioticresistance #antimicrobials