Lorraine Montel
@lorrainemontel.bsky.social
CNRS Researcher at Institute of Light and Matter (Univ Lyon1). Insterested in mechanics and mechanotransduction in macrophages, particularly during phagocytosis.
Reposted by Lorraine Montel
Do you want to do a PhD on exploring brain-body interactions with expansion microscopy at the Paris-Saclay Institute of Neuroscience, through the Marie-Curie COFUND program?
Apply!
Deadline : 23 February 2026
Supervisor : Tihana JOVANIC
lightinparis.eu
@neuropsi.bsky.social
Apply!
Deadline : 23 February 2026
Supervisor : Tihana JOVANIC
lightinparis.eu
@neuropsi.bsky.social
January 14, 2026 at 8:30 AM
Do you want to do a PhD on exploring brain-body interactions with expansion microscopy at the Paris-Saclay Institute of Neuroscience, through the Marie-Curie COFUND program?
Apply!
Deadline : 23 February 2026
Supervisor : Tihana JOVANIC
lightinparis.eu
@neuropsi.bsky.social
Apply!
Deadline : 23 February 2026
Supervisor : Tihana JOVANIC
lightinparis.eu
@neuropsi.bsky.social
Reposted by Lorraine Montel
Organelles do NOT have a single uniform pH.
And if you think they must, because “protons diffuse fast,” this paper is for you.
A thread on why that assumption is wrong; and what we found instead. 🧵 1/n
And if you think they must, because “protons diffuse fast,” this paper is for you.
A thread on why that assumption is wrong; and what we found instead. 🧵 1/n
Organelles harbour pH gradients https://www.biorxiv.org/content/10.64898/2025.12.12.694065v1
December 17, 2025 at 12:46 AM
Organelles do NOT have a single uniform pH.
And if you think they must, because “protons diffuse fast,” this paper is for you.
A thread on why that assumption is wrong; and what we found instead. 🧵 1/n
And if you think they must, because “protons diffuse fast,” this paper is for you.
A thread on why that assumption is wrong; and what we found instead. 🧵 1/n
Reposted by Lorraine Montel
Le premier article de la doctorante que je co-encadre vient d'être publié : journals.aps.org/pre/abstract... 🥳
(vous pouvez aussi le trouver sur ArXiv si vous avez très envie de le lire et n'êtes pas abonné/e aux journaux de l'APS : arxiv.org/abs/2506.06145)
(vous pouvez aussi le trouver sur ArXiv si vous avez très envie de le lire et n'êtes pas abonné/e aux journaux de l'APS : arxiv.org/abs/2506.06145)
Load-dependent power-law exponent in creep rupture of heterogeneous materials
Creep tests on heterogeneous materials under subcritical loading typically show a power-law decay in strain rate before failure, with the exponent often considered material dependent but independent o...
journals.aps.org
December 17, 2025 at 10:45 AM
Le premier article de la doctorante que je co-encadre vient d'être publié : journals.aps.org/pre/abstract... 🥳
(vous pouvez aussi le trouver sur ArXiv si vous avez très envie de le lire et n'êtes pas abonné/e aux journaux de l'APS : arxiv.org/abs/2506.06145)
(vous pouvez aussi le trouver sur ArXiv si vous avez très envie de le lire et n'êtes pas abonné/e aux journaux de l'APS : arxiv.org/abs/2506.06145)
Reposted by Lorraine Montel
Macrophage fireworks 🎆 from Miller et al. of the @mmorrissey.bsky.social lab (doi.org/10.1083/jcb....) showing a #macrophage expressing Vav1-mCherry (magenta) interacting with IgG (yellow) on a supported lipid bilayer containing ICAM-1. More in JCB's December issue: rupress.org/jcb/issue/22...
December 15, 2025 at 3:02 PM
Macrophage fireworks 🎆 from Miller et al. of the @mmorrissey.bsky.social lab (doi.org/10.1083/jcb....) showing a #macrophage expressing Vav1-mCherry (magenta) interacting with IgG (yellow) on a supported lipid bilayer containing ICAM-1. More in JCB's December issue: rupress.org/jcb/issue/22...
Reposted by Lorraine Montel
How does a macrophage decide to eat or simply nibble? Check out our latest paper! You can also read this nice review. Congrats Caitlin for leading this amazing work!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Target cell cortical tension regulates macrophage trogocytosis - Nature Cell Biology
Cornell et al. show that target cells with low cortical tension induce macrophages to preferentially trogocytose, or engulf in small fragments, whereas target cells with high cortical tension tend tow...
www.nature.com
December 15, 2025 at 10:51 PM
How does a macrophage decide to eat or simply nibble? Check out our latest paper! You can also read this nice review. Congrats Caitlin for leading this amazing work!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Lorraine Montel
De novo E-cadherin/catenin complex formation controls basal epithelial mechanics and force transmission for apoptotic cell clearance https://www.biorxiv.org/content/10.64898/2025.12.08.692667v1
December 9, 2025 at 6:30 PM
De novo E-cadherin/catenin complex formation controls basal epithelial mechanics and force transmission for apoptotic cell clearance https://www.biorxiv.org/content/10.64898/2025.12.08.692667v1
Reposted by Lorraine Montel
Happy to share that I will be presenting at #CellBio2025 this afternoon during the #CSCB session in room 108 our work on #phagocytosis by #macrophages mannose receptor done @institutcochin.bsky.social by @chiarapompili.bsky.social with @jfattaccioli.bsky.social and @jean-Maurice Mallet
December 8, 2025 at 3:02 PM
Happy to share that I will be presenting at #CellBio2025 this afternoon during the #CSCB session in room 108 our work on #phagocytosis by #macrophages mannose receptor done @institutcochin.bsky.social by @chiarapompili.bsky.social with @jfattaccioli.bsky.social and @jean-Maurice Mallet
Internship opportunity for a Master Student
@symux.bsky.social and I are looking for someone to work with us to answer this tantalizing question: does a phagocyte regulates its cell volume during and after phagocytosis?
If you are interested, please do not hesitate to contact us in DM or by e-mail.
@symux.bsky.social and I are looking for someone to work with us to answer this tantalizing question: does a phagocyte regulates its cell volume during and after phagocytosis?
If you are interested, please do not hesitate to contact us in DM or by e-mail.
December 2, 2025 at 4:17 PM
Internship opportunity for a Master Student
@symux.bsky.social and I are looking for someone to work with us to answer this tantalizing question: does a phagocyte regulates its cell volume during and after phagocytosis?
If you are interested, please do not hesitate to contact us in DM or by e-mail.
@symux.bsky.social and I are looking for someone to work with us to answer this tantalizing question: does a phagocyte regulates its cell volume during and after phagocytosis?
If you are interested, please do not hesitate to contact us in DM or by e-mail.
Reposted by Lorraine Montel
📢Internships on cellular nematics!
🔬Come for the pretty images, stay for the cool physics: each project combines in vitro experiments with advanced microscopy and image analysis.
📧Feel free to DM or email me with any questions.
🔬Come for the pretty images, stay for the cool physics: each project combines in vitro experiments with advanced microscopy and image analysis.
📧Feel free to DM or email me with any questions.
December 2, 2025 at 3:15 PM
📢Internships on cellular nematics!
🔬Come for the pretty images, stay for the cool physics: each project combines in vitro experiments with advanced microscopy and image analysis.
📧Feel free to DM or email me with any questions.
🔬Come for the pretty images, stay for the cool physics: each project combines in vitro experiments with advanced microscopy and image analysis.
📧Feel free to DM or email me with any questions.
Reposted by Lorraine Montel
New paper from the @rouxlab.bsky.social on Nature Communications! We study how membrane tension is spatially organized in cells. Using the mechanosensitive probe Flipper-TR to visualize tension across the plasma membrane of adherent cells and to dissect the conditions needed for a gradient to happen
November 27, 2025 at 2:14 PM
New paper from the @rouxlab.bsky.social on Nature Communications! We study how membrane tension is spatially organized in cells. Using the mechanosensitive probe Flipper-TR to visualize tension across the plasma membrane of adherent cells and to dissect the conditions needed for a gradient to happen
Reposted by Lorraine Montel
We introduce a microfluidic device that can trap, analyze, and release individual microparticles on demand using membrane deformation driven by pneumatic pressure. The setup uses a deformable membrane suspended over an array of traps.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Fully integrated automatic microfluidic setup for immobilization, analysis and non-selective release of particles
We present a microfluidic device that enables trapping, analysis and on-demand release of individual microparticles using membrane deformation induced…
www.sciencedirect.com
November 20, 2025 at 5:02 PM
We introduce a microfluidic device that can trap, analyze, and release individual microparticles on demand using membrane deformation driven by pneumatic pressure. The setup uses a deformable membrane suspended over an array of traps.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Reposted by Lorraine Montel
We introduce a modular biosensing strategy using targeted lipid microparticles to monitor phagosomal acidification in real time. These biomimetic particles are engineered to couple receptor-specific uptake with fluorescence-based pH reporting in macrophages.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
November 20, 2025 at 5:17 PM
We introduce a modular biosensing strategy using targeted lipid microparticles to monitor phagosomal acidification in real time. These biomimetic particles are engineered to couple receptor-specific uptake with fluorescence-based pH reporting in macrophages.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Lorraine Montel
We have TWO papers out in @jcb.org this month! 🎉
First, @kirstin-rollins.bsky.social showed that macrophages nibble adherent target cells, like the ones found in solid tumors, instead of phagocytosing. Amazing movies from @sareenfiaz.bsky.social
doi.org/10.1083/jcb....
First, @kirstin-rollins.bsky.social showed that macrophages nibble adherent target cells, like the ones found in solid tumors, instead of phagocytosing. Amazing movies from @sareenfiaz.bsky.social
doi.org/10.1083/jcb....
October 17, 2025 at 5:07 PM
We have TWO papers out in @jcb.org this month! 🎉
First, @kirstin-rollins.bsky.social showed that macrophages nibble adherent target cells, like the ones found in solid tumors, instead of phagocytosing. Amazing movies from @sareenfiaz.bsky.social
doi.org/10.1083/jcb....
First, @kirstin-rollins.bsky.social showed that macrophages nibble adherent target cells, like the ones found in solid tumors, instead of phagocytosing. Amazing movies from @sareenfiaz.bsky.social
doi.org/10.1083/jcb....
Reposted by Lorraine Montel
Target cell adhesion limits macrophage #phagocytosis and promotes #trogocytosis, say @kirstin-rollins.bsky.social, @mmorrissey.bsky.social et al.
@ucsantabarbara.bsky.social rupress.org/jcb/article/...
#Macrophages #Immunology
@ucsantabarbara.bsky.social rupress.org/jcb/article/...
#Macrophages #Immunology
October 10, 2025 at 3:15 PM
Target cell adhesion limits macrophage #phagocytosis and promotes #trogocytosis, say @kirstin-rollins.bsky.social, @mmorrissey.bsky.social et al.
@ucsantabarbara.bsky.social rupress.org/jcb/article/...
#Macrophages #Immunology
@ucsantabarbara.bsky.social rupress.org/jcb/article/...
#Macrophages #Immunology
Reposted by Lorraine Montel
Notre article en collaboration avec des chimistes de l'IRCELyon vient d'être publié dans ACS Applied Materials and Interfaces, je peux donc maintenant officiellement écrire sur mon CV que je suis un "material scientist" 🤭
pubs.acs.org/doi/10.1021/...
pubs.acs.org/doi/10.1021/...
July 22, 2025 at 4:06 PM
Notre article en collaboration avec des chimistes de l'IRCELyon vient d'être publié dans ACS Applied Materials and Interfaces, je peux donc maintenant officiellement écrire sur mon CV que je suis un "material scientist" 🤭
pubs.acs.org/doi/10.1021/...
pubs.acs.org/doi/10.1021/...
Reposted by Lorraine Montel
Join us for this @dgz.bsky.social seminar online with very cool talks about the Cell biology of the immune system
There will be of course some #CellMigration of leukocytes ;)
Speakers: @liz-kurtz.bsky.social, #ZahraaA, @labliston.bsky.social and #StefanU
There will be of course some #CellMigration of leukocytes ;)
Speakers: @liz-kurtz.bsky.social, #ZahraaA, @labliston.bsky.social and #StefanU
The next #DGZ Focus Workshop on #CellBiology of the #ImmuneSystem will take place on April 29, organized by @pjsaez.bsky.social & Evi Kiermaier – join us! 🧑🔬🧑🔬🧬
April 11, 2025 at 2:49 PM
Join us for this @dgz.bsky.social seminar online with very cool talks about the Cell biology of the immune system
There will be of course some #CellMigration of leukocytes ;)
Speakers: @liz-kurtz.bsky.social, #ZahraaA, @labliston.bsky.social and #StefanU
There will be of course some #CellMigration of leukocytes ;)
Speakers: @liz-kurtz.bsky.social, #ZahraaA, @labliston.bsky.social and #StefanU
Reposted by Lorraine Montel
Our latest publication on #macrophages congrats Anna Mularski and @manondepierre.bsky.social @institutcochin.bsky.social @actin-paris-saclay.bsky.social Martial Balland @grenoblealpes.bsky.social
@cnrsbiologie.bsky.social cnrs physique @anr
@cnrsbiologie.bsky.social cnrs physique @anr
Comment les macrophages sont influencés par leur environnement ? 🧐
Une récente étude menée par @florenceniedergang.bsky.social révèle que leur interaction avec leur milieu joue un rôle clé dans leur activité immunitaire !
Une récente étude menée par @florenceniedergang.bsky.social révèle que leur interaction avec leur milieu joue un rôle clé dans leur activité immunitaire !
L’interaction entre les macrophages et leur milieu environnant affecte leur fonctionnement
Les macrophages sont des cellules du système immunitaire qui ingèrent et dégradent les microorganismes et les débris cellulaires selon un processus appe
buff.ly
March 28, 2025 at 6:44 PM
Our latest publication on #macrophages congrats Anna Mularski and @manondepierre.bsky.social @institutcochin.bsky.social @actin-paris-saclay.bsky.social Martial Balland @grenoblealpes.bsky.social
@cnrsbiologie.bsky.social cnrs physique @anr
@cnrsbiologie.bsky.social cnrs physique @anr
Reposted by Lorraine Montel
Hi to all, we have open positions in the frame of a funded ANR, nickname Criticality, one in Marseille with me, two in Paris (P. Pierobon, Cochin / J. Husson, LadHyX). Can you spread around the word to young persons who could be interested in joining our project ?
To contact me : phpuech.github.io
To contact me : phpuech.github.io
Immunobiophysics
What do we do ?
phpuech.github.io
March 27, 2025 at 8:36 AM
Hi to all, we have open positions in the frame of a funded ANR, nickname Criticality, one in Marseille with me, two in Paris (P. Pierobon, Cochin / J. Husson, LadHyX). Can you spread around the word to young persons who could be interested in joining our project ?
To contact me : phpuech.github.io
To contact me : phpuech.github.io
Reposted by Lorraine Montel
We are excited to announce our next speaker for the immunobiophysics seminar series: Renaud Poincloux, from IPBS Toulouse, France.
The seminar will take place on March 27th at 16:30 CET (3:30 PM UTC). The Zoom link will be sent to you the day before the event.
The seminar will take place on March 27th at 16:30 CET (3:30 PM UTC). The Zoom link will be sent to you the day before the event.
Renaud Poincloux - IPBS-Toulouse
Cellular biologist studying the actin cytoskeleton using advanced cell imaging methods. Podosomaholic. Current positionCNRS research[…]
www.ipbs.fr
March 26, 2025 at 8:56 PM
We are excited to announce our next speaker for the immunobiophysics seminar series: Renaud Poincloux, from IPBS Toulouse, France.
The seminar will take place on March 27th at 16:30 CET (3:30 PM UTC). The Zoom link will be sent to you the day before the event.
The seminar will take place on March 27th at 16:30 CET (3:30 PM UTC). The Zoom link will be sent to you the day before the event.
Reposted by Lorraine Montel
Happy to share our new publication in
@naturematerials.bsky.social
on mechanical cell competition! Great collaboration between our CAM team, Chavrier's and Doostmohammadi's. Special congrats
@luanger.bsky.social, @andreasschoenit.bsky.social, Siavash Monfared! 🎉
www.nature.com/articles/s41...
@naturematerials.bsky.social
on mechanical cell competition! Great collaboration between our CAM team, Chavrier's and Doostmohammadi's. Special congrats
@luanger.bsky.social, @andreasschoenit.bsky.social, Siavash Monfared! 🎉
www.nature.com/articles/s41...
March 14, 2025 at 12:10 PM
Happy to share our new publication in
@naturematerials.bsky.social
on mechanical cell competition! Great collaboration between our CAM team, Chavrier's and Doostmohammadi's. Special congrats
@luanger.bsky.social, @andreasschoenit.bsky.social, Siavash Monfared! 🎉
www.nature.com/articles/s41...
@naturematerials.bsky.social
on mechanical cell competition! Great collaboration between our CAM team, Chavrier's and Doostmohammadi's. Special congrats
@luanger.bsky.social, @andreasschoenit.bsky.social, Siavash Monfared! 🎉
www.nature.com/articles/s41...