Anna Vasilevskaya
@loghyr.bsky.social
PhD student studying cortical computations in https://www.apredictiveprocessinglab.org
Reposted by Anna Vasilevskaya
1/6 New preprint 🚀 How does the cortex learn to represent things and how they move without reconstructing sensory stimuli? We developed a circuit-centric recurrent predictive learning (RPL) model based on JEPAs.
🔗 doi.org/10.1101/2025...
Led by @atenagm.bsky.social @mshalvagal.bsky.social
🔗 doi.org/10.1101/2025...
Led by @atenagm.bsky.social @mshalvagal.bsky.social
November 27, 2025 at 8:24 AM
1/6 New preprint 🚀 How does the cortex learn to represent things and how they move without reconstructing sensory stimuli? We developed a circuit-centric recurrent predictive learning (RPL) model based on JEPAs.
🔗 doi.org/10.1101/2025...
Led by @atenagm.bsky.social @mshalvagal.bsky.social
🔗 doi.org/10.1101/2025...
Led by @atenagm.bsky.social @mshalvagal.bsky.social
Reposted by Anna Vasilevskaya
One of the most promising approaches to making headway in understanding the cortical algorithm that I have seen in a long time! www.biorxiv.org/content/10.1...
Understanding cortical computation through the lens of joint-embedding predictive architectures
Tracking prey or recognizing a lurking predator is as crucial for survival as anticipating their actions. To guide behavior, the brain must extract information about object identities and their dynami...
www.biorxiv.org
November 26, 2025 at 1:54 PM
One of the most promising approaches to making headway in understanding the cortical algorithm that I have seen in a long time! www.biorxiv.org/content/10.1...
Reposted by Anna Vasilevskaya
Join us for the second Neurobiology of Mental Health conference (May 2026) that will explore the biological mechanisms underlying mental health challenges and their treatment. Information and application on: lakeconferences.org. The deadline for applications is January 31st, 2026.
Home - Lake Conferences
lakeconferences.org
October 13, 2025 at 4:47 PM
Join us for the second Neurobiology of Mental Health conference (May 2026) that will explore the biological mechanisms underlying mental health challenges and their treatment. Information and application on: lakeconferences.org. The deadline for applications is January 31st, 2026.
Reposted by Anna Vasilevskaya
How does the brain balance learning new things without overwriting what it already knows? Our new paper tackles this long-standing stability–plasticity dilemma during active navigation. With Tony Drinnenberg from the Deisseroth Lab (@deisseroth.bsky.social)
doi.org/10.1101/2025...
doi.org/10.1101/2025...
Environmental Novelty Modulates Rapid Cortical Plasticity During Navigation
In novel environments, animals quickly learn to navigate, and position-correlated spatial representations rapidly emerge in both the retrosplenial cortex (RSC) and primary visual cortex (V1). However,...
doi.org
October 24, 2025 at 3:40 AM
How does the brain balance learning new things without overwriting what it already knows? Our new paper tackles this long-standing stability–plasticity dilemma during active navigation. With Tony Drinnenberg from the Deisseroth Lab (@deisseroth.bsky.social)
doi.org/10.1101/2025...
doi.org/10.1101/2025...
Reposted by Anna Vasilevskaya
I’m super excited to finally put my recent work with @behrenstimb.bsky.social on bioRxiv, where we develop a new mechanistic theory of how PFC structures adaptive behaviour using attractor dynamics in space and time!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
September 24, 2025 at 12:04 PM
I’m super excited to finally put my recent work with @behrenstimb.bsky.social on bioRxiv, where we develop a new mechanistic theory of how PFC structures adaptive behaviour using attractor dynamics in space and time!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Anna Vasilevskaya
This year's Ruth Chiquet Prize goes to @solygamagda.bsky.social, who sent a video message, for her work on how the brain detects sensory mismatches. Read more at: www.fmi.ch/news-events/...
September 17, 2025 at 8:52 AM
This year's Ruth Chiquet Prize goes to @solygamagda.bsky.social, who sent a video message, for her work on how the brain detects sensory mismatches. Read more at: www.fmi.ch/news-events/...
Reposted by Anna Vasilevskaya
A new preprint from our lab with @zelechowski.bsky.social & @georgkeller.bsky.social !
Using wireless EEG + VR, we recorded visuomotor mismatch responses in freely moving humans.
Huge thanks to all participants, Keller Lab members and FMI facilities!
Read more: www.biorxiv.org/content/10.1...
Using wireless EEG + VR, we recorded visuomotor mismatch responses in freely moving humans.
Huge thanks to all participants, Keller Lab members and FMI facilities!
Read more: www.biorxiv.org/content/10.1...
August 19, 2025 at 1:39 PM
A new preprint from our lab with @zelechowski.bsky.social & @georgkeller.bsky.social !
Using wireless EEG + VR, we recorded visuomotor mismatch responses in freely moving humans.
Huge thanks to all participants, Keller Lab members and FMI facilities!
Read more: www.biorxiv.org/content/10.1...
Using wireless EEG + VR, we recorded visuomotor mismatch responses in freely moving humans.
Huge thanks to all participants, Keller Lab members and FMI facilities!
Read more: www.biorxiv.org/content/10.1...
Reposted by Anna Vasilevskaya
1/N What are the organizational principles underlying crossmodal cortical connections?
We address this in this new preprint, led by @alexegeaweiss.bsky.social & @bturner-bridger.bsky.social in collab w/ @petrznam.bsky.social @crick.ac.uk
www.biorxiv.org/content/10.1...
We address this in this new preprint, led by @alexegeaweiss.bsky.social & @bturner-bridger.bsky.social in collab w/ @petrznam.bsky.social @crick.ac.uk
www.biorxiv.org/content/10.1...
August 1, 2025 at 10:10 AM
1/N What are the organizational principles underlying crossmodal cortical connections?
We address this in this new preprint, led by @alexegeaweiss.bsky.social & @bturner-bridger.bsky.social in collab w/ @petrznam.bsky.social @crick.ac.uk
www.biorxiv.org/content/10.1...
We address this in this new preprint, led by @alexegeaweiss.bsky.social & @bturner-bridger.bsky.social in collab w/ @petrznam.bsky.social @crick.ac.uk
www.biorxiv.org/content/10.1...
Reposted by Anna Vasilevskaya
Ditching months-long delays for fast, constructive feedback.
This interview with @solygamagda.bsky.social dives into the experience of publishing with eLife and what it could mean for a more open and efficient future in science.
This interview with @solygamagda.bsky.social dives into the experience of publishing with eLife and what it could mean for a more open and efficient future in science.
Publishing with eLife: “the future of science lies in greater transparency”
Neuroscientist Magdalena Solyga shares her latest study and her experience publishing with eLife.
buff.ly
July 21, 2025 at 3:59 PM
Ditching months-long delays for fast, constructive feedback.
This interview with @solygamagda.bsky.social dives into the experience of publishing with eLife and what it could mean for a more open and efficient future in science.
This interview with @solygamagda.bsky.social dives into the experience of publishing with eLife and what it could mean for a more open and efficient future in science.
Reposted by Anna Vasilevskaya
100%, but also - the eLife experiment is a good reminer that we need experiments here. Open reviews were not a thing until they were, peer reviews were not a thing until they were, so did preprints, and the ability not to respond to reviewers comments etc. We can try to re-imagine publishing!
July 20, 2025 at 7:45 AM
100%, but also - the eLife experiment is a good reminer that we need experiments here. Open reviews were not a thing until they were, peer reviews were not a thing until they were, so did preprints, and the ability not to respond to reviewers comments etc. We can try to re-imagine publishing!
Reposted by Anna Vasilevskaya
Let's say you have a journal that isn't worried about protecting an impact factor, so it didn't need to package a million results into a single paper (to maximise citation-to-publication ratio). What would you do? Couple of suggestions below. Others very much appreciated!
July 5, 2025 at 8:37 AM
Let's say you have a journal that isn't worried about protecting an impact factor, so it didn't need to package a million results into a single paper (to maximise citation-to-publication ratio). What would you do? Couple of suggestions below. Others very much appreciated!
Reposted by Anna Vasilevskaya
SCN2A is a top risk gene for autism. But how does losing one copy of it affect dendritic function during flexible decision-making? 🧬🐭🧠🧪
Our study in preprint @biorxivpreprint: www.biorxiv.org/content/10.1...
Supported by a @simonsfoundation.org SFARI Pilot Award 🙌
#SCN2A #cureSCN2A
Our study in preprint @biorxivpreprint: www.biorxiv.org/content/10.1...
Supported by a @simonsfoundation.org SFARI Pilot Award 🙌
#SCN2A #cureSCN2A
June 24, 2025 at 12:50 PM
SCN2A is a top risk gene for autism. But how does losing one copy of it affect dendritic function during flexible decision-making? 🧬🐭🧠🧪
Our study in preprint @biorxivpreprint: www.biorxiv.org/content/10.1...
Supported by a @simonsfoundation.org SFARI Pilot Award 🙌
#SCN2A #cureSCN2A
Our study in preprint @biorxivpreprint: www.biorxiv.org/content/10.1...
Supported by a @simonsfoundation.org SFARI Pilot Award 🙌
#SCN2A #cureSCN2A
Reposted by Anna Vasilevskaya
I've spent much of my PhD thinking about E/I balance, and our latest preprint represents the culmination of that journey. Huge thanks to @fzenke.bsky.social for guiding me.
Looking forward to your thoughts & comments.
Looking forward to your thoughts & comments.
1/6 Why does the brain maintain such precise excitatory-inhibitory balance?
Our new preprint explores a provocative idea: Small, targeted deviations from this balance may serve a purpose: to encode local error signals for learning.
www.biorxiv.org/content/10.1...
led by @jrbch.bsky.social
Our new preprint explores a provocative idea: Small, targeted deviations from this balance may serve a purpose: to encode local error signals for learning.
www.biorxiv.org/content/10.1...
led by @jrbch.bsky.social
May 27, 2025 at 8:37 AM
I've spent much of my PhD thinking about E/I balance, and our latest preprint represents the culmination of that journey. Huge thanks to @fzenke.bsky.social for guiding me.
Looking forward to your thoughts & comments.
Looking forward to your thoughts & comments.
Reposted by Anna Vasilevskaya
Forelimb movement control at the basal ganglia - brainstem interface!
Happy to finally share this work from me and @harsh-kanodia.bsky.social with Silvia Arber!
@biozentrum.unibas.ch @fmiscience.bsky.social
www.nature.com/articles/s41...
Happy to finally share this work from me and @harsh-kanodia.bsky.social with Silvia Arber!
@biozentrum.unibas.ch @fmiscience.bsky.social
www.nature.com/articles/s41...
Dynamic basal ganglia output signals license and suppress forelimb movements - Nature
Basal ganglia output neurons fire dynamically in bidirectional and movement-specific patterns to license forelimb movements.
www.nature.com
May 28, 2025 at 3:32 PM
Forelimb movement control at the basal ganglia - brainstem interface!
Happy to finally share this work from me and @harsh-kanodia.bsky.social with Silvia Arber!
@biozentrum.unibas.ch @fmiscience.bsky.social
www.nature.com/articles/s41...
Happy to finally share this work from me and @harsh-kanodia.bsky.social with Silvia Arber!
@biozentrum.unibas.ch @fmiscience.bsky.social
www.nature.com/articles/s41...
Reposted by Anna Vasilevskaya
If you're planning a course with mathematical methods content, or use such methods in your own work, please take a look at "Mathematics in Biology", by Meister, Lee, and Portugues, published at MIT Press. 1/2 @portugueslab.bsky.social mitpress.mit.edu/978026204940...
Mathematics in Biology
Biology has turned into a quantitative science. The core problems in the life sciences today involve complex systems that require mathematical expression, ye...
mitpress.mit.edu
May 21, 2025 at 9:53 PM
If you're planning a course with mathematical methods content, or use such methods in your own work, please take a look at "Mathematics in Biology", by Meister, Lee, and Portugues, published at MIT Press. 1/2 @portugueslab.bsky.social mitpress.mit.edu/978026204940...
Reposted by Anna Vasilevskaya
A few words on our latest paper and where we're heading next ⬇️
What happens when our senses defy expectations—like hearing a delayed step? A study by Magdalena Solyga and @georgkeller.bsky.social revealed how the brain handles sensory surprises, with insights that could aid psychiatric diagnosis and tracking. www.fmi.ch/news-events/...
How the brain detects surprises — and why it could matter for mental health
What happens in the brain when our senses don’t match our expectations — for example, when we take a step, but there’s no sound or the sound is delayed or distorted? A new study led by FMI neuroscient...
www.fmi.ch
May 8, 2025 at 6:58 AM
A few words on our latest paper and where we're heading next ⬇️
Reposted by Anna Vasilevskaya
How does our brain predict the future? Our review of predictive processing + research program is now on arXiv arxiv.org/abs/2504.09614
50+ neuroscientists distributed across the world worked together to create this unique community project.
50+ neuroscientists distributed across the world worked together to create this unique community project.
April 15, 2025 at 6:58 AM
How does our brain predict the future? Our review of predictive processing + research program is now on arXiv arxiv.org/abs/2504.09614
50+ neuroscientists distributed across the world worked together to create this unique community project.
50+ neuroscientists distributed across the world worked together to create this unique community project.
Reposted by Anna Vasilevskaya
3/3
We are looking for a lab technician, a lab manager and researchers to join us in this new chapter. Read the post here: portugueslab.com/the-lab-is-h...
Reach out to us if you are interested.
We are looking for a lab technician, a lab manager and researchers to join us in this new chapter. Read the post here: portugueslab.com/the-lab-is-h...
Reach out to us if you are interested.
portugueslab.com
April 2, 2025 at 1:02 PM
3/3
We are looking for a lab technician, a lab manager and researchers to join us in this new chapter. Read the post here: portugueslab.com/the-lab-is-h...
Reach out to us if you are interested.
We are looking for a lab technician, a lab manager and researchers to join us in this new chapter. Read the post here: portugueslab.com/the-lab-is-h...
Reach out to us if you are interested.
Reposted by Anna Vasilevskaya
Consistent with the work of @jeremiahycohen.bsky.social and @mishaahrens.bsky.social labs, we find that serotonin axons in mouse visual cortex appear to signal recent visuomotor uncertainty (and unlike norepinephrine axons, they have no visuomotor mismatch responses) www.biorxiv.org/content/10.1...
Activity in serotonergic axons in visuomotor areas of cortex is modulated by the recent history of visuomotor coupling
Visuomotor experience is necessary for the development of normal function of visual cortex (Attinger et al., 2017) and likely establishes a balance between movement-related predictions and sensory sig...
www.biorxiv.org
March 13, 2025 at 11:29 AM
Consistent with the work of @jeremiahycohen.bsky.social and @mishaahrens.bsky.social labs, we find that serotonin axons in mouse visual cortex appear to signal recent visuomotor uncertainty (and unlike norepinephrine axons, they have no visuomotor mismatch responses) www.biorxiv.org/content/10.1...
Reposted by Anna Vasilevskaya
🎉 It’s been over two years since we launched the eLife Model for publishing that places the focus on nuanced public assessments instead of publishing outcomes.
1/ Here’s how it’s going: buff.ly/wnJrXie
1/ Here’s how it’s going: buff.ly/wnJrXie
March 5, 2025 at 4:01 PM
🎉 It’s been over two years since we launched the eLife Model for publishing that places the focus on nuanced public assessments instead of publishing outcomes.
1/ Here’s how it’s going: buff.ly/wnJrXie
1/ Here’s how it’s going: buff.ly/wnJrXie
Reposted by Anna Vasilevskaya
If only we had a system like @elife.bsky.social where peer review was public and accountable, we wouldn’t have to “rely” on peer review to “validate” papers!
"The scientific literature is an essential ocean of knowledge, in which floats an alarming amount of junk."
Reflecting on RFK Jr.'s use of scholarly papers in his confirmation hearings.
Reflecting on RFK Jr.'s use of scholarly papers in his confirmation hearings.
The Scientific Literature Can’t Save Us Now
You can cite peer-reviewed research in support of almost any claim, no matter how absurd.
www.theatlantic.com
February 16, 2025 at 3:47 PM
If only we had a system like @elife.bsky.social where peer review was public and accountable, we wouldn’t have to “rely” on peer review to “validate” papers!
Reposted by Anna Vasilevskaya
Paper in eLife from Solyga & Keller on responses in auditory cortex to multi-modal mismatches:
elifesciences.org/reviewed-pre...
🧠📈 🧪
elifesciences.org/reviewed-pre...
🧠📈 🧪
Multimodal mismatch responses in mouse auditory cortex
elifesciences.org
November 20, 2024 at 8:21 PM
Paper in eLife from Solyga & Keller on responses in auditory cortex to multi-modal mismatches:
elifesciences.org/reviewed-pre...
🧠📈 🧪
elifesciences.org/reviewed-pre...
🧠📈 🧪
Reposted by Anna Vasilevskaya
Join us for the Sensation and Action conference 2025 – application is now open: lakeconferences.org
Home - Lake Conferences
lakeconferences.org
November 22, 2024 at 5:44 PM
Join us for the Sensation and Action conference 2025 – application is now open: lakeconferences.org
Reposted by Anna Vasilevskaya
Why is reality so slow? Why can we only have one thought at a time? Why do we need so many neurons? Will Elon Musk's Neuralink really speed up his cognition? For answers and more questions check out our new review: "The Unbearable Slowness of Being". arxiv.org/abs/2408.10234
The Unbearable Slowness of Being
This article is about the neural conundrum behind the slowness of human behavior. The information throughput of a human being is about 10 bits/s. In comparison, our sensory systems gather data at...
arxiv.org
August 21, 2024 at 4:45 PM
Why is reality so slow? Why can we only have one thought at a time? Why do we need so many neurons? Will Elon Musk's Neuralink really speed up his cognition? For answers and more questions check out our new review: "The Unbearable Slowness of Being". arxiv.org/abs/2408.10234