Lewis MacKenzie
@lemackz.bsky.social
Upconversion nanoparticles, optical biosensors, chiral spectroscopy, scicomm, blood oxygen | bass player | uranium glass collector
Group website: www.mackenzie-lab.org
he/him | Glasgow | Expect typos
Group website: www.mackenzie-lab.org
he/him | Glasgow | Expect typos
Pinned
Lewis MacKenzie
@lemackz.bsky.social
· Aug 19
Very excited to announce that I will be a Royal Society University Research Fellow (URF)! This will enable me to expand my team and purchase the specialist equipment required to make upconversion nanoparticles easier to synthesize and to develop them as biomedical research tools. #ChemSky
Sunset from my office in Glasgow - you can spot Tinto and High Street train station
November 25, 2025 at 4:04 PM
Sunset from my office in Glasgow - you can spot Tinto and High Street train station
Reposted by Lewis MacKenzie
Looking for some help! I'm putting together materials for a postdoc workshop on writing cover letters and abstracts for general journals like Science, Nature, PNAS. Any advice, tips, or resources to share? I will compile and share back! 🧪😀
November 24, 2025 at 8:31 PM
Looking for some help! I'm putting together materials for a postdoc workshop on writing cover letters and abstracts for general journals like Science, Nature, PNAS. Any advice, tips, or resources to share? I will compile and share back! 🧪😀
Light-activated pain-free drug delivery into skin using #upconverison nanoparticle constructs - exciting work! This specific application is for IVF drug release.
onlinelibrary.wiley.com/doi/pdf/10.1...
onlinelibrary.wiley.com/doi/pdf/10.1...
Upconverting Nanoparticle‐Loaded Microneedles for Near‐Infrared Responsive Delivery of Gonadotropins to Increase Success of In Vitro Fertilization
This paper describes the development of an upconverting particle-integrated microneedle patch that can release the hormone leuprolide when the patch is exposed to near-infrared light. This system rep...
onlinelibrary.wiley.com
November 24, 2025 at 10:30 AM
Light-activated pain-free drug delivery into skin using #upconverison nanoparticle constructs - exciting work! This specific application is for IVF drug release.
onlinelibrary.wiley.com/doi/pdf/10.1...
onlinelibrary.wiley.com/doi/pdf/10.1...
Reposted by Lewis MacKenzie
I tried an even harder example on Gemini Pro image generation and this is quite scary/amazing. I asked for a microscopy image of around 20 HeLa cells, GFP tagged 20% nuclear, 10% membrane, +1 nuclear staining, + overlap. Image below and prompt in the following post.
November 21, 2025 at 5:32 PM
I tried an even harder example on Gemini Pro image generation and this is quite scary/amazing. I asked for a microscopy image of around 20 HeLa cells, GFP tagged 20% nuclear, 10% membrane, +1 nuclear staining, + overlap. Image below and prompt in the following post.
Reposted by Lewis MacKenzie
Bad antibodies are a major roadblock in biomedical research, harming reproducibility and wasting resources.
The International Antibody Validation Meeting was created to fix it.
Watch the talks from the 5th Antibody Validation Meeting (2025)
tinyurl.com/AntibodyVali...
#Integrity #reproducibility
The International Antibody Validation Meeting was created to fix it.
Watch the talks from the 5th Antibody Validation Meeting (2025)
tinyurl.com/AntibodyVali...
#Integrity #reproducibility
5th International Antibody Validation Meeting - YouTube
Listen to talks from the speakers at the 5th AbVal meeting, held in Bath on the 9-11th September 2025.
tinyurl.com
November 22, 2025 at 10:57 AM
Bad antibodies are a major roadblock in biomedical research, harming reproducibility and wasting resources.
The International Antibody Validation Meeting was created to fix it.
Watch the talks from the 5th Antibody Validation Meeting (2025)
tinyurl.com/AntibodyVali...
#Integrity #reproducibility
The International Antibody Validation Meeting was created to fix it.
Watch the talks from the 5th Antibody Validation Meeting (2025)
tinyurl.com/AntibodyVali...
#Integrity #reproducibility
Cool use of hybrid upconversion nanomaterials!
Researchers have developed micrometer-scale micromotors that glide through the air on convection currents and could one day be used for gas-phase heterogeneous catalysis, aerosol toxin detection and pollution control.
Read the story: https://bit.ly/4idJvgr
#technology #micromotors 💡 ⚛️ 🧪
Read the story: https://bit.ly/4idJvgr
#technology #micromotors 💡 ⚛️ 🧪
November 21, 2025 at 10:59 PM
Cool use of hybrid upconversion nanomaterials!
Trio of yellow Victorian (1870s) uranium glass vases in string directional daylight. The green fluorescence can be seen even in this bright sunlight! #uraniumglass
November 20, 2025 at 11:19 AM
Trio of yellow Victorian (1870s) uranium glass vases in string directional daylight. The green fluorescence can be seen even in this bright sunlight! #uraniumglass
Reposted by Lewis MacKenzie
The subgenre deep dive for this week’s @realmsunknown.bsky.social is Villain-as-hero.
@tpneenan.bsky.social is our guest and he just watched the new Predator movie where one of the ruthless murder-monsters is Our Cool Protagonist.
Let me know your favourite villain as hero texts!
@tpneenan.bsky.social is our guest and he just watched the new Predator movie where one of the ruthless murder-monsters is Our Cool Protagonist.
Let me know your favourite villain as hero texts!
November 9, 2025 at 7:16 PM
The subgenre deep dive for this week’s @realmsunknown.bsky.social is Villain-as-hero.
@tpneenan.bsky.social is our guest and he just watched the new Predator movie where one of the ruthless murder-monsters is Our Cool Protagonist.
Let me know your favourite villain as hero texts!
@tpneenan.bsky.social is our guest and he just watched the new Predator movie where one of the ruthless murder-monsters is Our Cool Protagonist.
Let me know your favourite villain as hero texts!
Clever assay format - using a pipette tip as cuvette and incubator/reactor!
pubs.acs.org/doi/full/10....
pubs.acs.org/doi/full/10....
October 28, 2025 at 4:25 PM
Clever assay format - using a pipette tip as cuvette and incubator/reactor!
pubs.acs.org/doi/full/10....
pubs.acs.org/doi/full/10....
Reposted by Lewis MacKenzie
Hey seabird folks - have you ever thought "*ANOTHER* talk about ?!" So did we.
So we reviewed 3000 conference abstracts to see which species get the spotlight. Huge work from @ingridpollet.bsky.social with me and @seabirdsentinel.bsky.social
www.sciencedirect.com/science/arti...
So we reviewed 3000 conference abstracts to see which species get the spotlight. Huge work from @ingridpollet.bsky.social with me and @seabirdsentinel.bsky.social
www.sciencedirect.com/science/arti...
October 25, 2025 at 9:51 AM
Hey seabird folks - have you ever thought "*ANOTHER* talk about ?!" So did we.
So we reviewed 3000 conference abstracts to see which species get the spotlight. Huge work from @ingridpollet.bsky.social with me and @seabirdsentinel.bsky.social
www.sciencedirect.com/science/arti...
So we reviewed 3000 conference abstracts to see which species get the spotlight. Huge work from @ingridpollet.bsky.social with me and @seabirdsentinel.bsky.social
www.sciencedirect.com/science/arti...
Reposted by Lewis MacKenzie
This building has a strange kind of charisma
(Livingston Tower, University of Strathclyde)
(Livingston Tower, University of Strathclyde)
October 20, 2025 at 4:46 PM
This building has a strange kind of charisma
(Livingston Tower, University of Strathclyde)
(Livingston Tower, University of Strathclyde)
What an awesome conference week for #SHIFTtenerife! I can highly recommend it for anyone into lanthanide luminescence and upconversion! Excellent science, a wonderful community, and beautiful location! #chemsky
October 17, 2025 at 5:50 PM
What an awesome conference week for #SHIFTtenerife! I can highly recommend it for anyone into lanthanide luminescence and upconversion! Excellent science, a wonderful community, and beautiful location! #chemsky
Very excited to be at the #SHIFT conference in Tenerife! Going to be lots of lanthanide and upconversion talks, as well as a big speech from Ben Ferringa this morning! #chemsky
#SHIFTtenerife
#SHIFTtenerife
October 13, 2025 at 7:22 AM
Very excited to be at the #SHIFT conference in Tenerife! Going to be lots of lanthanide and upconversion talks, as well as a big speech from Ben Ferringa this morning! #chemsky
#SHIFTtenerife
#SHIFTtenerife
Reposted by Lewis MacKenzie
There's still time to apply for our Dorothy Hodgkin Fellowships. This scheme offers a first step into an independent research career for outstanding early career scientists who require flexible working circumstances.
#RSGrants
https://bit.ly/4h1hzf3
#RSGrants
https://bit.ly/4h1hzf3
October 10, 2025 at 12:45 PM
There's still time to apply for our Dorothy Hodgkin Fellowships. This scheme offers a first step into an independent research career for outstanding early career scientists who require flexible working circumstances.
#RSGrants
https://bit.ly/4h1hzf3
#RSGrants
https://bit.ly/4h1hzf3
Reposted by Lewis MacKenzie
The connection between Nobel-prize winning MOFs and Mudéjar maybe goes beyond beautiful geometric structures – @davidfairen.bsky.social believes the first ever metal-organic framework could be a compound discovered in my hometown, Zaragoza, in 1973. www.chemistryworld.com/opinion/my-a...
My arcane and curious connection to metal-organic frameworks
Fernando Gomollón-Bel uncovers a link between his hometown and the 2025 Nobel prize in chemistry
www.chemistryworld.com
October 10, 2025 at 9:27 AM
The connection between Nobel-prize winning MOFs and Mudéjar maybe goes beyond beautiful geometric structures – @davidfairen.bsky.social believes the first ever metal-organic framework could be a compound discovered in my hometown, Zaragoza, in 1973. www.chemistryworld.com/opinion/my-a...
If anyone wants some numbers on this: a study I led found that ~70% of chemistry YouTube channels are geared towards revision/learning, and that the creators largely do not clearly state their own professional background/qualifications.
royalsocietypublishing.org/doi/10.1098/...
royalsocietypublishing.org/doi/10.1098/...
October 10, 2025 at 9:40 AM
If anyone wants some numbers on this: a study I led found that ~70% of chemistry YouTube channels are geared towards revision/learning, and that the creators largely do not clearly state their own professional background/qualifications.
royalsocietypublishing.org/doi/10.1098/...
royalsocietypublishing.org/doi/10.1098/...
Reposted by Lewis MacKenzie
On train listening to obviously smart teenage boys discussing homework on “how is conflict presented in Romeo and Juliet” and one boy says to another “I’ll send you two good videos on this” and I am not sure teachers are fully aware of how young people revise etc these days.
October 10, 2025 at 6:48 AM
On train listening to obviously smart teenage boys discussing homework on “how is conflict presented in Romeo and Juliet” and one boy says to another “I’ll send you two good videos on this” and I am not sure teachers are fully aware of how young people revise etc these days.
@alicefraser.bsky.social scunnered to hear about the extremely crap way you've been treated by your publisher, but I'm so excited about the 'A Passion for Passion' audiobook! I can't wait to buy and listen to it! 🤩🎧
October 9, 2025 at 4:16 PM
@alicefraser.bsky.social scunnered to hear about the extremely crap way you've been treated by your publisher, but I'm so excited about the 'A Passion for Passion' audiobook! I can't wait to buy and listen to it! 🤩🎧
Reposted by Lewis MacKenzie
🧪⚒️ “the complex organic molecules Cassini detected…are not just a product of long exposure to space, but are readily available in Enceladus’s ocean.”
As ever - these observations show some intriguing chemistry is going on, but that isn’t necessarily life.
As ever - these observations show some intriguing chemistry is going on, but that isn’t necessarily life.
Cassini proves complex chemistry in Enceladus ocean
Scientists digging through data collected by the Cassini spacecraft have found new complex organic molecules spewing from Saturn’s moon Enceladus. This is a clear sign that complex chemical reactions ...
www.esa.int
October 1, 2025 at 11:32 AM
🧪⚒️ “the complex organic molecules Cassini detected…are not just a product of long exposure to space, but are readily available in Enceladus’s ocean.”
As ever - these observations show some intriguing chemistry is going on, but that isn’t necessarily life.
As ever - these observations show some intriguing chemistry is going on, but that isn’t necessarily life.
Reposted by Lewis MacKenzie
Benzyl chloroformate is not trivial to come by. Been waiting on an order from Acros. Does anyone know 1. where to get it from fairly quickly and/or 2. alternatives to benzyl chloroformate for making Cbz-protected amines. (Yes it needs to be Cbz protected.) #chemsky 🧪
October 1, 2025 at 11:50 AM
Benzyl chloroformate is not trivial to come by. Been waiting on an order from Acros. Does anyone know 1. where to get it from fairly quickly and/or 2. alternatives to benzyl chloroformate for making Cbz-protected amines. (Yes it needs to be Cbz protected.) #chemsky 🧪
Another beautiful #uraniumglass trinket set 🤩
September 29, 2025 at 8:01 PM
Another beautiful #uraniumglass trinket set 🤩
Finally found the back of my knee on Anthony Boudain's Parts Unknown S5 E1
September 27, 2025 at 9:28 PM
Finally found the back of my knee on Anthony Boudain's Parts Unknown S5 E1
Reposted by Lewis MacKenzie
#Mars
A swarm of spherical rovers, blown by the wind like tumbleweeds, could enable large-scale and low-cost exploration of the Martian surface.
www.europlanet.org/epsc-dps2025... 🧪 #PlanetSci
Video: field tests with the Tumbleweed Science Testbed. Credit: Team Tumbleweed/Sas Schilten.
A swarm of spherical rovers, blown by the wind like tumbleweeds, could enable large-scale and low-cost exploration of the Martian surface.
www.europlanet.org/epsc-dps2025... 🧪 #PlanetSci
Video: field tests with the Tumbleweed Science Testbed. Credit: Team Tumbleweed/Sas Schilten.
September 27, 2025 at 5:27 PM
#Mars
A swarm of spherical rovers, blown by the wind like tumbleweeds, could enable large-scale and low-cost exploration of the Martian surface.
www.europlanet.org/epsc-dps2025... 🧪 #PlanetSci
Video: field tests with the Tumbleweed Science Testbed. Credit: Team Tumbleweed/Sas Schilten.
A swarm of spherical rovers, blown by the wind like tumbleweeds, could enable large-scale and low-cost exploration of the Martian surface.
www.europlanet.org/epsc-dps2025... 🧪 #PlanetSci
Video: field tests with the Tumbleweed Science Testbed. Credit: Team Tumbleweed/Sas Schilten.