Kyle Card
@kylejcard.bsky.social
HHMI Hanna Gray Fellow at the Cleveland Clinic studying drug resistance evolution w/ Jacob Scott 💊 | HHMI Gilliam Fellow & Ph.D. w/ Richard Lenski | #DisabledInSTEM 🦾 | He/Him
To make sense of this stochasticity, we introduced the Collateral Response Score, a probabilistic framework for forecasting how prior treatment history shapes future drug options.
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September 27, 2025 at 5:35 PM
To make sense of this stochasticity, we introduced the Collateral Response Score, a probabilistic framework for forecasting how prior treatment history shapes future drug options.
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The answer: evolution doesn’t just increase vancomycin resistance — it reshapes the bacterium’s response to the very drugs we’d normally switch to next. Some lineages become collaterally sensitive, while others become collaterally resistant, depending on the evolutionary path they take.
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September 27, 2025 at 5:33 PM
The answer: evolution doesn’t just increase vancomycin resistance — it reshapes the bacterium’s response to the very drugs we’d normally switch to next. Some lineages become collaterally sensitive, while others become collaterally resistant, depending on the evolutionary path they take.
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Thrilled to share our paper that just came out in PNAS!
We asked a deceptively simple question: What happens when S. aureus adapts to vancomycin, a critical first-line antibiotic?
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We asked a deceptively simple question: What happens when S. aureus adapts to vancomycin, a critical first-line antibiotic?
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September 27, 2025 at 5:32 PM
Thrilled to share our paper that just came out in PNAS!
We asked a deceptively simple question: What happens when S. aureus adapts to vancomycin, a critical first-line antibiotic?
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We asked a deceptively simple question: What happens when S. aureus adapts to vancomycin, a critical first-line antibiotic?
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We're standing up for science in Columbus, OH
March 7, 2025 at 8:13 PM
We're standing up for science in Columbus, OH