koenvervaeke.bsky.social
@koenvervaeke.bsky.social
Reposted
I am really proud that eLife have published this paper. It is a very nice paper, but you need to also read the reviews to understand why! 1/n
"The inevitability and superfluousness of cell types in spatial cognition". Intuitive cell types are found in random artificial networks using the same selection criteria neuroscientists use with actual data. elifesciences.org/reviewed-pre... 1/2
elifesciences.org
November 25, 2025 at 8:34 PM
Reposted
Surprising immune-neural function shown by Simone at the Imperial College London!
www.nature.com/articles/s41...
Macrophages excite muscle spindles with glutamate to bolster locomotion - Nature
A population of macrophages with exclusive molecular and functional signatures in the muscle spindles express machinery for synthesizing and releasing glutamate, and a cellular component, the muscle s...
www.nature.com
November 22, 2025 at 1:48 AM
Reposted
Funding wise, this seems to be my year 💪🤩

Now setting up an interdisciplinary convergence environment to figure out mechanisms of OPRM1 mutation & importance for addiction

Co-PIs @koenvervaeke @deopandey @osmangani

www.uio.no/english/rese...
www.uio.no
November 5, 2025 at 11:58 AM
Reposted
How does the brain balance learning new things without overwriting what it already knows? Our new paper tackles this long-standing stability–plasticity dilemma during active navigation. With Tony Drinnenberg from the Deisseroth Lab (@deisseroth.bsky.social)
doi.org/10.1101/2025...
Environmental Novelty Modulates Rapid Cortical Plasticity During Navigation
In novel environments, animals quickly learn to navigate, and position-correlated spatial representations rapidly emerge in both the retrosplenial cortex (RSC) and primary visual cortex (V1). However,...
doi.org
October 24, 2025 at 3:40 AM
Reposted
Please RT
2 new positions in the lab as postdoc & PhD!

Interested in stress, pain, or reward? This project has it all!

We are a friendly but ambitious group. Oslo is a capital city on the fjord & bordered by forest, great urban & outdoors opportunities: 💃 ⛷️ 🚣 🎭 🎶

www.jobbnorge.no/en/available...
Postdoctoral Research Fellowship (286516) | University of Oslo
Job title: Postdoctoral Research Fellowship (286516), Employer: University of Oslo, Deadline: Wednesday, October 15, 2025
www.jobbnorge.no
September 24, 2025 at 12:22 PM
Reposted
🧪 We got the privilege to write a Preview on the beautiful work of Morabito, Zerlaut, Rebola and colleagues that was recently published in Neuron. www.sciencedirect.com/science/arti...
Branch logic: Dendritic computations diversify inhibition
Long known for different circuit roles, parvalbumin and somatostatin interneurons are shown by Morabito et al.,1 in this issue of Neuron, to differ in…
www.sciencedirect.com
September 21, 2025 at 4:59 PM
Reposted
Ripple contributions to human memory: making the spiking content count — a Review by Joel Reithler, Kelsey K. Sundby & Kareem A. Zaghloul

www.nature.com/articles/s41...

#neuroscience #neuroskyence
Ripple contributions to human memory: making the spiking content count - Nature Reviews Neuroscience
In animal models, transient high-frequency oscillations in synchronized neural activity, known as ripples, have been linked to memory. Reithler et al. assess the current evidence for a contribution of...
www.nature.com
September 18, 2025 at 10:41 AM
Reposted
Check out this exciting study led by Anh-Tuan Trinh from our lab, where we investigated how thalamocortical-like circuits in the zebrafish pallium receive, represent, and integrate sensory information:
🔗 doi.org/10.1101/2025...
Hierarchical processing of sensory information across topographically organized thalamocortical-like circuits in the zebrafish brain
Thalamocortical projections contribute to the spatial organization and functional hierarchies of the mammalian cortex. Primary sensory cortices receive topographically segregated information from firs...
doi.org
September 16, 2025 at 12:54 PM
Reposted
Human intelligence is overrated and not a useful yardstick for AI - a polemic. markusmeister.com/2025/09/15/w...
September 15, 2025 at 3:15 AM
Reposted
This type of textbook chapter review of neural manifolds has been so needed. Thank you for writing this. It's excellent.

rdcu.be/eGjAu
A neural manifold view of the brain
Nature Neuroscience - Recent advances in neuroscience have revealed how neural population activity underlying behavior can be well described by topological objects called neural manifolds....
rdcu.be
September 15, 2025 at 2:12 AM
Reposted
Our first steps into sensory processing is now online!
Work spearheaded by Rejwan Salih from experiments by @prime5222.bsky.social and François Pauzin
We were lucky to receive guidance from Davide Zoccolan on the analytical methods.
#neuroskyence
Tactile responses in the mouse perirhinal cortex show invariance to physical features of the stimulus https://www.biorxiv.org/content/10.1101/2025.08.15.670508v1
August 21, 2025 at 5:01 PM
Reposted
What can *genetic insensitivity to opioids* teach us about endogenous opioid function in humans?

Fully funded position in Oslo (PhD student or postdoc)

Interested in pain, mu/kappa opioids, behavioural genetics, RCTs, or related? Apply here:
2411.webcruiter.no/Main2/Recrui...

Please RT for reach
Phd candidate or postdoc– Genetic determinants of opioid responsiveness
The Department of Research and Development at the Division of Emergencies and Critical Care, Oslo University Hospital in collaboration with Leknes Affective Brain lab (www.affectivebrains.com) and the...
2411.webcruiter.no
August 29, 2025 at 2:20 PM
Reposted
This comment is 3 minutes long, and it's from back in February. It bears repeating.

"Curiosity-driven, peer-reviewed research is not meant to pass the politician's test."

x.com/RepAuchinclo... (1/2)
x.com
August 27, 2025 at 6:04 AM
Reposted
Can't wait to read this preprint from Misha Ahrens and team. Calcium imaging in larval zebrafish, in every cell in the body! Amazing.

www.biorxiv.org/content/10.1...
August 22, 2025 at 10:21 PM
A piece of neuroscience history. The original "Oslo chamber", possibly the first one to be used for holding brain slices.
July 23, 2025 at 11:38 AM
Reposted
Has anyone got any experience with gcamp8 transgenic mice yet? Eg the Thy1-GCaMP8s line?

janelia.figshare.com/articles/dat...
jGCaMP8 transgenic mice
The GENIE Project Team at HHMI Janelia Research Campus have developed and characterized multiple transgenic mice expressing jGCaMP8s and jGCaMP8m and deposited the lines at The Jackson Laboratory (JAX...
janelia.figshare.com
July 15, 2025 at 9:30 AM
Reposted
Our collaboration - from PhD work - examining input-specific (EC L3) contributions to rate and temporal coding in CA1 place cells is now out in @natcomms.nature.com 🔬🧠

rdcu.be/evWtz
Direct entorhinal control of CA1 temporal coding
Nature Communications - Temporal coding in the hippocampus is thought to be key for memory and predictions. Here, the authors show that blocking one entorhinal input affects two aspects of...
rdcu.be
July 12, 2025 at 5:09 PM
Reposted
Opening new neuroscience horizons:
With this tool, we can study dendritic computation and network dynamics under naturalistic behavior: an essential step toward understanding the neural basis of cognition. 🌍🧠
July 10, 2025 at 8:36 AM
Reposted
These insights enable stimulation “tuning” to target specific functions. This work also highlights how flicker stimulation has multiple biological effects and we think such a multipotent therapeutic approach is required for neurodegenerative diseases. This study was made possible by Levi Wood’s lab
Frequency and duration of sensory flicker control transcriptional profiles in 5xFAD mice
Current clinical trials are investigating gamma frequency sensory stimulation as a potential therapeutic strategy for Alzheimer's disease (AD); yet, we lack a c
doi.org
July 10, 2025 at 3:09 PM
Reposted
Glymphatic dysfunction in Alzheimer’s disease: A critical appraisal | Science www.science.org/doi/10.1126/...
Glymphatic dysfunction in Alzheimer’s disease: A critical appraisal
Thirteen years after the initial publication defining the glymphatic system, we critically reappraise the role of its dysfunction in Alzheimer’s disease (AD). Our understanding of glymphatic function ...
www.science.org
July 10, 2025 at 8:50 PM
Reposted
Physicists have a lot to say about time, but so do neuroscientists -- after all, it's the brain which in some sense creates time, and enables our remarkable capacity for "mental time travel." I spoke with neuroscientist @deanbuono.bsky.social for @nautil.us:
nautil.us/does-anybody... #science
Does Anybody Really Know What Time Is?
Yes, your brain does. It created it.
nautil.us
July 9, 2025 at 3:55 PM
Reposted
📣New study in Neuron, featuring modeling insights: "Cell-Specific Dendritic Integration in Cortical GABAergic Interneurons"! It reveals PV & SST interneurons compute differently. This highlights how distinct dendrites enable specialized brain computations!

www.sciencedirect.com/science/arti...
Distinct dendritic integration strategies control dynamics of inhibition in the neocortex
Dendrites critically influence single-neuron computations, but their role in neocortical GABAergic interneurons (INs) remains poorly understood. We fo…
www.sciencedirect.com
July 3, 2025 at 10:12 AM
Reposted
New blog post with a review of interesting papers on VIP interneurons in cortex and hippocampus: gcamp6f.com/2025/06/23/i...
Covering work from @koenvervaeke.bsky.social's lab with @mateneubrandt.bsky.social, Yoav Adam's lab and Bernardo Rudy's lab.
June 23, 2025 at 1:04 PM