Josh Gertler
@joshuagertler.bsky.social
Clinical Psych PhD Student at UF, interested in emotion neuroscience research.
Reposted by Josh Gertler
Excited to share our cross-disorder GWAS analysis of neurological and psychiatric disorders (~1 M cases), now out in @natneuro.nature.com! We show more extensive genetic pleiotropy than previously recognized, supporting a more unified view of these disorders
rdcu.be/ePmwD
rdcu.be/ePmwD
A genome-wide analysis of the shared genetic risk architecture of complex neurological and psychiatric disorders
Nature Neuroscience - Smeland et al. demonstrate greater genetic overlap between neurological and psychiatric disorders than previously recognized, along with diverse neurobiological associations....
rdcu.be
November 12, 2025 at 12:12 PM
Excited to share our cross-disorder GWAS analysis of neurological and psychiatric disorders (~1 M cases), now out in @natneuro.nature.com! We show more extensive genetic pleiotropy than previously recognized, supporting a more unified view of these disorders
rdcu.be/ePmwD
rdcu.be/ePmwD
Reposted by Josh Gertler
From big to small: Emerging methods for enhancing precision psychiatry through transfer learning www.sciencedirect.com/science/arti...
From big to small: Emerging methods for enhancing precision psychiatry through transfer learning
Identifying reliable links between individual differences in neurobiological features and differences in symptom profiles or treatment outcomes is a p…
www.sciencedirect.com
November 3, 2025 at 3:37 PM
From big to small: Emerging methods for enhancing precision psychiatry through transfer learning www.sciencedirect.com/science/arti...
Reposted by Josh Gertler
Reposted by Josh Gertler
I’m seriously intrigued by this. How are brains set up such that 4 lbs of wonderful in 2 hours doesn’t spiral into mania? That’s robust & highly nontrivial integration!
November 1, 2025 at 12:21 AM
I’m seriously intrigued by this. How are brains set up such that 4 lbs of wonderful in 2 hours doesn’t spiral into mania? That’s robust & highly nontrivial integration!
Reposted by Josh Gertler
Overall social media use is declining.
Between 2020 and 2024, more Americans — especially the youngest (18–24) and oldest (65+) — report using no social media at all.
A small group of heavy users remains, but the middle is thinning out.
Between 2020 and 2024, more Americans — especially the youngest (18–24) and oldest (65+) — report using no social media at all.
A small group of heavy users remains, but the middle is thinning out.
October 30, 2025 at 8:09 AM
Overall social media use is declining.
Between 2020 and 2024, more Americans — especially the youngest (18–24) and oldest (65+) — report using no social media at all.
A small group of heavy users remains, but the middle is thinning out.
Between 2020 and 2024, more Americans — especially the youngest (18–24) and oldest (65+) — report using no social media at all.
A small group of heavy users remains, but the middle is thinning out.
Reposted by Josh Gertler
Interested in using the PCL-5 to measure PTSD symptoms in your EMA study?
We conducted item analysis to examine item thresholds & discrimination parameters & examined DIF across daily surveys
www.sciencedirect.com/science/arti...
We conducted item analysis to examine item thresholds & discrimination parameters & examined DIF across daily surveys
www.sciencedirect.com/science/arti...
Psychometric evaluation of the Posttraumatic Stress Disorder Checklist for DSM-5 in daily surveys: An item response theory and longitudinal measurement invariance analysis
The Posttraumatic Stress Disorder (PTSD) Checklist for the DSM-5 (PCL-5) has demonstrated excellent psychometric qualities across cross-sectional stud…
www.sciencedirect.com
October 22, 2025 at 9:32 PM
Interested in using the PCL-5 to measure PTSD symptoms in your EMA study?
We conducted item analysis to examine item thresholds & discrimination parameters & examined DIF across daily surveys
www.sciencedirect.com/science/arti...
We conducted item analysis to examine item thresholds & discrimination parameters & examined DIF across daily surveys
www.sciencedirect.com/science/arti...
Reposted by Josh Gertler
@matthiasmichel.bsky.social and I are beavering away reading and responding to all the excellent commentaries on our BBS paper outlining an evolutionary account of visual consciousness.
In the meantime, if you missed our target article, it's available here:
www.cambridge.org/core/journal...
In the meantime, if you missed our target article, it's available here:
www.cambridge.org/core/journal...
Sensory Horizons and the Functions of Conscious Vision | Behavioral and Brain Sciences | Cambridge Core
Sensory Horizons and the Functions of Conscious Vision
www.cambridge.org
October 2, 2025 at 2:00 PM
@matthiasmichel.bsky.social and I are beavering away reading and responding to all the excellent commentaries on our BBS paper outlining an evolutionary account of visual consciousness.
In the meantime, if you missed our target article, it's available here:
www.cambridge.org/core/journal...
In the meantime, if you missed our target article, it's available here:
www.cambridge.org/core/journal...
Reposted by Josh Gertler
PCI Psychology! psych.peercommunityin.org
PCI Psychology
Peer Community in Psychology
psych.peercommunityin.org
October 1, 2025 at 1:01 AM
PCI Psychology! psych.peercommunityin.org
Reposted by Josh Gertler
We're a month further into the job market - how are things looking? The good news is that the market does seem to have been delayed: ~150 new listings have appeared since my last post. The bad news is that the total is still substantially lower than what it was during the covid dip.
October 3, 2025 at 5:26 PM
We're a month further into the job market - how are things looking? The good news is that the market does seem to have been delayed: ~150 new listings have appeared since my last post. The bad news is that the total is still substantially lower than what it was during the covid dip.
Reposted by Josh Gertler
Intervening on a central node in a network likely does little given that its connected neighbors will "flip it back" immediately. Happy to see this position supported now.
"Change is most likely [..] if it spreads first among relatively poorly connected nodes."
www.nature.com/articles/s41...
"Change is most likely [..] if it spreads first among relatively poorly connected nodes."
www.nature.com/articles/s41...
Transformation starts at the periphery of networks where pushback is less - Scientific Reports
Scientific Reports - Transformation starts at the periphery of networks where pushback is less
www.nature.com
September 29, 2025 at 9:16 AM
Intervening on a central node in a network likely does little given that its connected neighbors will "flip it back" immediately. Happy to see this position supported now.
"Change is most likely [..] if it spreads first among relatively poorly connected nodes."
www.nature.com/articles/s41...
"Change is most likely [..] if it spreads first among relatively poorly connected nodes."
www.nature.com/articles/s41...
Reposted by Josh Gertler
Super proud of this collaboration with rockstar Ryan Raut - born out of playing in the sandbox in our last year of grad school! Multi-scale brain activity can be predicted from a simple measure of arousal like pupil diameter. Out with linear causality, in with dynamic systems to explain neurobiology
Arousal as a universal embedding for spatiotemporal brain dynamics - Nature
Reframing of arousal as a latent dynamical system can reconstruct multidimensional measurements of large-scale spatiotemporal brain dynamics on the timescale of seconds in mice.
www.nature.com
September 24, 2025 at 9:52 PM
Super proud of this collaboration with rockstar Ryan Raut - born out of playing in the sandbox in our last year of grad school! Multi-scale brain activity can be predicted from a simple measure of arousal like pupil diameter. Out with linear causality, in with dynamic systems to explain neurobiology
Reposted by Josh Gertler
In this video, Andy Jahn discusses the latest developments in #SPM, the latest release #SPM25 and our recent #SPM Homecoming with the wonderful @corticalpete.bsky.social, @liviasimela.bsky.social and @johmedr.bsky.social.
youtu.be/VqzvUPV7pk8?...
youtu.be/VqzvUPV7pk8?...
SPM Homecoming & SPM25 | Prof. Peter Zeidman, Dr. Olivia Kowalczyk & Dr. Johan Medrano
YouTube video by Andy's Brain Tube
youtu.be
September 26, 2025 at 10:00 AM
In this video, Andy Jahn discusses the latest developments in #SPM, the latest release #SPM25 and our recent #SPM Homecoming with the wonderful @corticalpete.bsky.social, @liviasimela.bsky.social and @johmedr.bsky.social.
youtu.be/VqzvUPV7pk8?...
youtu.be/VqzvUPV7pk8?...
Reposted by Josh Gertler
Our new paper is out now in Neuron! 🎉 With @vaibhavtripathi.bsky.social @maxwellelliott.bsky.social Joanna Ladopoulou, Wendy Sun, Mark Eldaief, and Randy Buckner
Paper link: www.sciencedirect.com/science/arti...
Paper link: www.sciencedirect.com/science/arti...
September 26, 2025 at 3:25 PM
Our new paper is out now in Neuron! 🎉 With @vaibhavtripathi.bsky.social @maxwellelliott.bsky.social Joanna Ladopoulou, Wendy Sun, Mark Eldaief, and Randy Buckner
Paper link: www.sciencedirect.com/science/arti...
Paper link: www.sciencedirect.com/science/arti...
Reposted by Josh Gertler
Lab’s latest is out in Imaging Neuroscience, led by Kirsten Peterson: “Regularized partial correlation provides reliable functional connectivity estimates while correcting for widespread confounding”, where we demonstrate a major improvement to standard fMRI functional connectivity (correlation) 1/n
September 14, 2025 at 9:34 PM
Lab’s latest is out in Imaging Neuroscience, led by Kirsten Peterson: “Regularized partial correlation provides reliable functional connectivity estimates while correcting for widespread confounding”, where we demonstrate a major improvement to standard fMRI functional connectivity (correlation) 1/n
Reposted by Josh Gertler
8/ In contrast to standard power calculations, our results suggest that jointly optimizing sample size and scan time can boost prediction accuracy while cutting costs. For more complex study design, you can check out our calculator: thomasyeolab.github.io/OptimalScanT...
July 17, 2025 at 1:36 AM
8/ In contrast to standard power calculations, our results suggest that jointly optimizing sample size and scan time can boost prediction accuracy while cutting costs. For more complex study design, you can check out our calculator: thomasyeolab.github.io/OptimalScanT...
Reposted by Josh Gertler
1/11 Excited to share our @Naturestudy led by @leonooi.bsky.social @csabaorban.bsky.social @shaoshiz.bsky.social
AI performance is known to scale with logarithm of sample size (Kaplan 2020), but in many domains, sample size can be # participants or # measurements...
doi.org/10.1038/s415...
AI performance is known to scale with logarithm of sample size (Kaplan 2020), but in many domains, sample size can be # participants or # measurements...
doi.org/10.1038/s415...
July 17, 2025 at 1:36 AM
1/11 Excited to share our @Naturestudy led by @leonooi.bsky.social @csabaorban.bsky.social @shaoshiz.bsky.social
AI performance is known to scale with logarithm of sample size (Kaplan 2020), but in many domains, sample size can be # participants or # measurements...
doi.org/10.1038/s415...
AI performance is known to scale with logarithm of sample size (Kaplan 2020), but in many domains, sample size can be # participants or # measurements...
doi.org/10.1038/s415...
Reposted by Josh Gertler
Dreaming of a dataset that tracks mood, sleep & activity to better understand affective instability (AI)…AND paired with advanced MRI? 🤯
Check out our new bioRxiv preprint for a 13–23 y/o community sample (n=10 and growing!) with multi-echo fMRI, EMA & actigraphy: www.biorxiv.org/content/10.1...
Check out our new bioRxiv preprint for a 13–23 y/o community sample (n=10 and growing!) with multi-echo fMRI, EMA & actigraphy: www.biorxiv.org/content/10.1...
May 6, 2025 at 3:32 PM
Dreaming of a dataset that tracks mood, sleep & activity to better understand affective instability (AI)…AND paired with advanced MRI? 🤯
Check out our new bioRxiv preprint for a 13–23 y/o community sample (n=10 and growing!) with multi-echo fMRI, EMA & actigraphy: www.biorxiv.org/content/10.1...
Check out our new bioRxiv preprint for a 13–23 y/o community sample (n=10 and growing!) with multi-echo fMRI, EMA & actigraphy: www.biorxiv.org/content/10.1...
Reposted by Josh Gertler
A putative neural correlate of mood!
One big (scandalous?) idea, simple analyses, and the STRONGEST brain/behavior correlation I've EVER seen (which is shocking, given that it's mood).
Work with: You-Ping Yang, @catrinahacker.bsky.social and Veit Stuphorn.
www.biorxiv.org/content/10.1...
One big (scandalous?) idea, simple analyses, and the STRONGEST brain/behavior correlation I've EVER seen (which is shocking, given that it's mood).
Work with: You-Ping Yang, @catrinahacker.bsky.social and Veit Stuphorn.
www.biorxiv.org/content/10.1...
The representation of mood in primate anterior insular cortex
Understanding how the brain reflects and shapes mood requires resolving the disconnect between behavioral measures of mood that can only be made in humans (typically based on subjective reports of hap...
www.biorxiv.org
April 25, 2025 at 1:49 PM
A putative neural correlate of mood!
One big (scandalous?) idea, simple analyses, and the STRONGEST brain/behavior correlation I've EVER seen (which is shocking, given that it's mood).
Work with: You-Ping Yang, @catrinahacker.bsky.social and Veit Stuphorn.
www.biorxiv.org/content/10.1...
One big (scandalous?) idea, simple analyses, and the STRONGEST brain/behavior correlation I've EVER seen (which is shocking, given that it's mood).
Work with: You-Ping Yang, @catrinahacker.bsky.social and Veit Stuphorn.
www.biorxiv.org/content/10.1...
Reposted by Josh Gertler
It's shocking how little is known about the brainstem red nucleus. In our new paper “The human brainstem’s red nucleus was upgraded to support goal-directed action” out now in @naturecomms.bsky.social we show that current thinking on the red nucleus is in need of a serious upgrade. rdcu.be/ehbOy
April 10, 2025 at 3:46 PM
It's shocking how little is known about the brainstem red nucleus. In our new paper “The human brainstem’s red nucleus was upgraded to support goal-directed action” out now in @naturecomms.bsky.social we show that current thinking on the red nucleus is in need of a serious upgrade. rdcu.be/ehbOy
Reposted by Josh Gertler
Reposted by Josh Gertler
It's finally here! Use the Network Correspondence Toolbox to help contextualize your neuroimaging findings 🧠
A network correspondence toolbox for quantitative evaluation of novel neuroimaging results - Nature Communications
Here, the authors present the Network Correspondence Toolbox, which enables researchers to examine and report spatial correspondence between their neuroimaging results and widely used brain atlases.
www.nature.com
March 26, 2025 at 1:54 AM
It's finally here! Use the Network Correspondence Toolbox to help contextualize your neuroimaging findings 🧠
Reposted by Josh Gertler
Thanks to everyone's feedback, we have updated our calculator to optimize sample size N & scan time T for fMRI studies: leonoqr.github.io/ORSP_Calcula...
The first new feature is that users can explore how different N & T leads to different accuracy, e.g., N=1000 & T=30min => 81% max accuracy. 🧵
The first new feature is that users can explore how different N & T leads to different accuracy, e.g., N=1000 & T=30min => 81% max accuracy. 🧵
January 24, 2025 at 12:02 AM
Thanks to everyone's feedback, we have updated our calculator to optimize sample size N & scan time T for fMRI studies: leonoqr.github.io/ORSP_Calcula...
The first new feature is that users can explore how different N & T leads to different accuracy, e.g., N=1000 & T=30min => 81% max accuracy. 🧵
The first new feature is that users can explore how different N & T leads to different accuracy, e.g., N=1000 & T=30min => 81% max accuracy. 🧵
Reposted by Josh Gertler
Reposted by Josh Gertler
ManyShortT1s - direct.mit.edu/imag/article...
Precision brain morphometry using cluster scanning
Abstract. Measurement error limits the statistical power to detect group differences and longitudinal change in structural MRI morphometric measures (e.g., hippocampal volume, prefrontal cortical thic...
direct.mit.edu
March 23, 2025 at 1:56 PM
ManyShortT1s - direct.mit.edu/imag/article...
Reposted by Josh Gertler
Beyond Mechanism—Extending Our Concepts of Causation in Neuroscience onlinelibrary.wiley.com/doi/10.1111/... - really pleased that this paper with Henry Potter is now published in the European Journal of Neuroscience 😊
Beyond Mechanism—Extending Our Concepts of Causation in Neuroscience
The search for neural mechanisms of behaviour often relies on a synchronic, driving view of causation, where neural activity drives more neural activity, which eventually drives behaviour. The real c...
onlinelibrary.wiley.com
March 14, 2025 at 10:25 AM
Beyond Mechanism—Extending Our Concepts of Causation in Neuroscience onlinelibrary.wiley.com/doi/10.1111/... - really pleased that this paper with Henry Potter is now published in the European Journal of Neuroscience 😊