Jonathan Ryder, MD
@jonathanrydermd.bsky.social
Adult ID and Assistant Prof at UNMC | Former IUSM IM & Truman State | Abx Stewie, Infxn Prevention, Digital MedEd, Podcasts, Medical History, Reading Non-Fiction, Running/Cycling | Posts are mine
Oral watermelon and RIF with rectal INH, ethambutol and/or enrofloxacin for 12-18 months? Very interesting article. Apparently costs $20K per elephant per year and the elephants didn't like it much
pmc.ncbi.nlm.nih.gov/articles/PMC...
pmc.ncbi.nlm.nih.gov/articles/PMC...
November 12, 2025 at 7:57 PM
Oral watermelon and RIF with rectal INH, ethambutol and/or enrofloxacin for 12-18 months? Very interesting article. Apparently costs $20K per elephant per year and the elephants didn't like it much
pmc.ncbi.nlm.nih.gov/articles/PMC...
pmc.ncbi.nlm.nih.gov/articles/PMC...
November 11, 2025 at 7:42 PM
This study was very nice to illustrate differences in rates of Pseudomonas DFI in differing parts of the US. Here in Nebraska, it must be the right mixture of cold and dry, very very low rates of PsA in DFI. And this study matches our local data almost exactly
academic.oup.com/ofid/article...
academic.oup.com/ofid/article...
October 27, 2025 at 4:34 PM
This study was very nice to illustrate differences in rates of Pseudomonas DFI in differing parts of the US. Here in Nebraska, it must be the right mixture of cold and dry, very very low rates of PsA in DFI. And this study matches our local data almost exactly
academic.oup.com/ofid/article...
academic.oup.com/ofid/article...
Just watched the session on sepsis today and its a great preview of a future replacement for SEP-1 that's been submitted to CMS as well as a guidance document for best practices in sepsis that is coming out from an IDSA committee
October 25, 2025 at 4:43 AM
Just watched the session on sepsis today and its a great preview of a future replacement for SEP-1 that's been submitted to CMS as well as a guidance document for best practices in sepsis that is coming out from an IDSA committee
@nkusnikmd.bsky.social presenting our blood culture shortage experience during an oral abstract session appropriately titled “A Bloody Mess!” @idweek.bsky.social #IDWeek2025 @unmc-id.bsky.social
October 21, 2025 at 7:39 PM
@nkusnikmd.bsky.social presenting our blood culture shortage experience during an oral abstract session appropriately titled “A Bloody Mess!” @idweek.bsky.social #IDWeek2025 @unmc-id.bsky.social
@takamatsuo-id.bsky.social presenting back-to-back oral abstracts on bone and joint infections @idweek.bsky.social! #IDWeek2025
October 21, 2025 at 3:25 PM
@takamatsuo-id.bsky.social presenting back-to-back oral abstracts on bone and joint infections @idweek.bsky.social! #IDWeek2025
Got to take a ride in my first Waymo last night! #IDWeek2025
October 21, 2025 at 11:54 AM
Got to take a ride in my first Waymo last night! #IDWeek2025
Let’s go!!! Hope to meet many of you at tonight’s social media meet-up! #IDWeek2025 @idweek.bsky.social
October 19, 2025 at 4:24 PM
Let’s go!!! Hope to meet many of you at tonight’s social media meet-up! #IDWeek2025 @idweek.bsky.social
I'll be there, come join the SoMe meet-up!
October 10, 2025 at 3:18 AM
I'll be there, come join the SoMe meet-up!
Very important nuance! Here is the authors' discussion on sample sizes and futility calculations:
Seems to me like it was powered for a decrease in mortality of 12-15% or so depending on recruitment numbers? Bayesian designs are complex!
academic.oup.com/cid/article/...
Seems to me like it was powered for a decrease in mortality of 12-15% or so depending on recruitment numbers? Bayesian designs are complex!
academic.oup.com/cid/article/...
July 16, 2025 at 3:34 PM
Very important nuance! Here is the authors' discussion on sample sizes and futility calculations:
Seems to me like it was powered for a decrease in mortality of 12-15% or so depending on recruitment numbers? Bayesian designs are complex!
academic.oup.com/cid/article/...
Seems to me like it was powered for a decrease in mortality of 12-15% or so depending on recruitment numbers? Bayesian designs are complex!
academic.oup.com/cid/article/...
New from @lancetrespirmed.bsky.social:
Adjunctive steroids for severe PJP in non-HIV patients
Non-sig decrease in 28-day mortality with steroids (32.4% vs 21.5%, p=0.069)
Lower in-hospital mortality, 90-day all-cause mortality & MV
www.thelancet.com/journals/lan...
Adjunctive steroids for severe PJP in non-HIV patients
Non-sig decrease in 28-day mortality with steroids (32.4% vs 21.5%, p=0.069)
Lower in-hospital mortality, 90-day all-cause mortality & MV
www.thelancet.com/journals/lan...
July 11, 2025 at 5:34 PM
New from @lancetrespirmed.bsky.social:
Adjunctive steroids for severe PJP in non-HIV patients
Non-sig decrease in 28-day mortality with steroids (32.4% vs 21.5%, p=0.069)
Lower in-hospital mortality, 90-day all-cause mortality & MV
www.thelancet.com/journals/lan...
Adjunctive steroids for severe PJP in non-HIV patients
Non-sig decrease in 28-day mortality with steroids (32.4% vs 21.5%, p=0.069)
Lower in-hospital mortality, 90-day all-cause mortality & MV
www.thelancet.com/journals/lan...
Was pretty cool...but its in the middle of nowhere...lol
July 3, 2025 at 1:27 AM
Was pretty cool...but its in the middle of nowhere...lol
I've been there!
Is it penicillin or is it metronidazole, given these were made from some beaver-like creatures?! Did they have Giardia in the Miocene?!
Is it penicillin or is it metronidazole, given these were made from some beaver-like creatures?! Did they have Giardia in the Miocene?!
July 3, 2025 at 1:18 AM
I've been there!
Is it penicillin or is it metronidazole, given these were made from some beaver-like creatures?! Did they have Giardia in the Miocene?!
Is it penicillin or is it metronidazole, given these were made from some beaver-like creatures?! Did they have Giardia in the Miocene?!
New from MMWR:
WNV and Other Arboviruses in 2023
High incidence states for WNV: CO, NE, ND
#IDSky
www.cdc.gov/mmwr/volumes...
WNV and Other Arboviruses in 2023
High incidence states for WNV: CO, NE, ND
#IDSky
www.cdc.gov/mmwr/volumes...
June 13, 2025 at 4:04 AM
New from MMWR:
WNV and Other Arboviruses in 2023
High incidence states for WNV: CO, NE, ND
#IDSky
www.cdc.gov/mmwr/volumes...
WNV and Other Arboviruses in 2023
High incidence states for WNV: CO, NE, ND
#IDSky
www.cdc.gov/mmwr/volumes...
Feeling quite refreshed after another awesome Nebraska Antimicrobial Stewardship Summit today! Always impressed by the speakers and enjoy the networking across the state at this annual event. Was great meeting @athorpe8.bsky.social @helennewland.bsky.social and many others! #IDSky #AMSky
May 31, 2025 at 12:09 AM
Feeling quite refreshed after another awesome Nebraska Antimicrobial Stewardship Summit today! Always impressed by the speakers and enjoy the networking across the state at this annual event. Was great meeting @athorpe8.bsky.social @helennewland.bsky.social and many others! #IDSky #AMSky
Just finished listening to the audiobook version of Booster Shots by @adamratnermd.bsky.social
Incredible history of measles including modern outbreaks, contextualizes the antivax movement, and is extremely prescient and timely. Highly recommend #IDSky
Incredible history of measles including modern outbreaks, contextualizes the antivax movement, and is extremely prescient and timely. Highly recommend #IDSky
April 10, 2025 at 3:17 AM
Just finished listening to the audiobook version of Booster Shots by @adamratnermd.bsky.social
Incredible history of measles including modern outbreaks, contextualizes the antivax movement, and is extremely prescient and timely. Highly recommend #IDSky
Incredible history of measles including modern outbreaks, contextualizes the antivax movement, and is extremely prescient and timely. Highly recommend #IDSky
Invasive GAS in children in Canada 1992-2023 @jama.com Open Network
Large increase in incidence in 2023, mostly emm12 and emm28
Clindamycin resistance uncommon (3% overall)
iGAS related to varicella has disappeared!
#IDSky @joshosowicki.bsky.social
jamanetwork.com/journals/jam...
Large increase in incidence in 2023, mostly emm12 and emm28
Clindamycin resistance uncommon (3% overall)
iGAS related to varicella has disappeared!
#IDSky @joshosowicki.bsky.social
jamanetwork.com/journals/jam...
April 4, 2025 at 5:05 PM
Invasive GAS in children in Canada 1992-2023 @jama.com Open Network
Large increase in incidence in 2023, mostly emm12 and emm28
Clindamycin resistance uncommon (3% overall)
iGAS related to varicella has disappeared!
#IDSky @joshosowicki.bsky.social
jamanetwork.com/journals/jam...
Large increase in incidence in 2023, mostly emm12 and emm28
Clindamycin resistance uncommon (3% overall)
iGAS related to varicella has disappeared!
#IDSky @joshosowicki.bsky.social
jamanetwork.com/journals/jam...
Survey of US adults <65 yo comparing abx non-users to frequent users (>3x/year) in @jama.com Open
Frequent abx users more likely to distrust science, want abx for viral URIs, need health literacy support, be medical maximizers, and had more comorbidities
#IDSky
jamanetwork.com/journals/jam...
Frequent abx users more likely to distrust science, want abx for viral URIs, need health literacy support, be medical maximizers, and had more comorbidities
#IDSky
jamanetwork.com/journals/jam...
March 23, 2025 at 5:27 PM
Survey of US adults <65 yo comparing abx non-users to frequent users (>3x/year) in @jama.com Open
Frequent abx users more likely to distrust science, want abx for viral URIs, need health literacy support, be medical maximizers, and had more comorbidities
#IDSky
jamanetwork.com/journals/jam...
Frequent abx users more likely to distrust science, want abx for viral URIs, need health literacy support, be medical maximizers, and had more comorbidities
#IDSky
jamanetwork.com/journals/jam...
From @drtoddlee.bsky.social @dremilymcd.bsky.social @angelahuttner.bsky.social @josemolinagb.bsky.social et al in @jama.com Network Open:
Systematic review & Non-inferiority Meta-Analysis of 7 vs 14 days for GNR BSI
4 RCTs, 7 non-inf to 14
#IDSky #ShorterIsBetter
jamanetwork.com/journals/jam...
Systematic review & Non-inferiority Meta-Analysis of 7 vs 14 days for GNR BSI
4 RCTs, 7 non-inf to 14
#IDSky #ShorterIsBetter
jamanetwork.com/journals/jam...
March 23, 2025 at 5:20 PM
From @drtoddlee.bsky.social @dremilymcd.bsky.social @angelahuttner.bsky.social @josemolinagb.bsky.social et al in @jama.com Network Open:
Systematic review & Non-inferiority Meta-Analysis of 7 vs 14 days for GNR BSI
4 RCTs, 7 non-inf to 14
#IDSky #ShorterIsBetter
jamanetwork.com/journals/jam...
Systematic review & Non-inferiority Meta-Analysis of 7 vs 14 days for GNR BSI
4 RCTs, 7 non-inf to 14
#IDSky #ShorterIsBetter
jamanetwork.com/journals/jam...
@escmid.bsky.social published their planned guidelines for development from 2025-2029 in @cmicomms.bsky.social #IDSky
What upcoming ESCMID guidelines are you most excited about in the next 5 years?!
Mine? Invasive Strep & Catheter Infxns!
www.clinicalmicrobiologyandinfection.com/article/S119...
What upcoming ESCMID guidelines are you most excited about in the next 5 years?!
Mine? Invasive Strep & Catheter Infxns!
www.clinicalmicrobiologyandinfection.com/article/S119...
March 23, 2025 at 2:49 AM
@escmid.bsky.social published their planned guidelines for development from 2025-2029 in @cmicomms.bsky.social #IDSky
What upcoming ESCMID guidelines are you most excited about in the next 5 years?!
Mine? Invasive Strep & Catheter Infxns!
www.clinicalmicrobiologyandinfection.com/article/S119...
What upcoming ESCMID guidelines are you most excited about in the next 5 years?!
Mine? Invasive Strep & Catheter Infxns!
www.clinicalmicrobiologyandinfection.com/article/S119...
That's legit....unlike my halloween costume this year lol
March 22, 2025 at 6:11 PM
That's legit....unlike my halloween costume this year lol
Cannot thank @drandrekalil.bsky.social enough for inviting me to write this commentary on the BALANCE trial for ACP Journal Club in @annalsofim.bsky.social this month!
#ShorterIsBetter #IDSky @unmc-id.bsky.social
www.acpjournals.org/doi/10.7326/...
#ShorterIsBetter #IDSky @unmc-id.bsky.social
www.acpjournals.org/doi/10.7326/...
March 4, 2025 at 3:44 AM
Cannot thank @drandrekalil.bsky.social enough for inviting me to write this commentary on the BALANCE trial for ACP Journal Club in @annalsofim.bsky.social this month!
#ShorterIsBetter #IDSky @unmc-id.bsky.social
www.acpjournals.org/doi/10.7326/...
#ShorterIsBetter #IDSky @unmc-id.bsky.social
www.acpjournals.org/doi/10.7326/...
Like different authors? I imagine it’s a similar group but don’t know as I’m not involved.
Here are the future sections:
Here are the future sections:
March 3, 2025 at 6:01 AM
Like different authors? I imagine it’s a similar group but don’t know as I’m not involved.
Here are the future sections:
Here are the future sections: