Jee-Yon Lee
@jeylee.bsky.social
MD, PhD | Assistant Project Scientist in the Bäumler Lab at UC Davis. | Studying the impact of host-microbial interactions on non-communicable human diseases.
Reposted by Jee-Yon Lee
🧵 How does being a #vegan, #vegetarian or omnivore impact your gut #microbiome? 🥦 Find out in our new paper on gut microbiome signatures of vegan, vegetarian & omnivore diets & associated health outcomes across 21,561 individuals in @naturemicrobiol.bsky.social!🎉 1/10
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Gut microbiome signatures of vegan, vegetarian and omnivore diets and associated health outcomes across 21,561 individuals - Nature Microbiology
Using 21,561 individuals, the authors present a cross-sectional study of how gut microbiome signatures are associated with dietary intake patterns and with host health outcomes.
www.nature.com
January 7, 2025 at 9:30 AM
🧵 How does being a #vegan, #vegetarian or omnivore impact your gut #microbiome? 🥦 Find out in our new paper on gut microbiome signatures of vegan, vegetarian & omnivore diets & associated health outcomes across 21,561 individuals in @naturemicrobiol.bsky.social!🎉 1/10
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Jee-Yon Lee
We showed that #metaproteomics based "Stable isotope fingerprinting can directly link intestinal microorganisms with their carbon source and captures diet-induced substrate switching in vivo"
www.biorxiv.org/content/10.1...
Great work by Angie Mordant and Alfredo Blakeley-Ruiz @alfredob.bsky.social
www.biorxiv.org/content/10.1...
Great work by Angie Mordant and Alfredo Blakeley-Ruiz @alfredob.bsky.social
Stable isotope fingerprinting can directly link intestinal microorganisms with their carbon source and captures diet-induced substrate switching in vivo
Diet has strong impacts on the composition and function of the gut microbiota with implications for host health. Therefore, it is critical to identify the dietary components that support growth of spe...
www.biorxiv.org
December 27, 2024 at 5:18 PM
We showed that #metaproteomics based "Stable isotope fingerprinting can directly link intestinal microorganisms with their carbon source and captures diet-induced substrate switching in vivo"
www.biorxiv.org/content/10.1...
Great work by Angie Mordant and Alfredo Blakeley-Ruiz @alfredob.bsky.social
www.biorxiv.org/content/10.1...
Great work by Angie Mordant and Alfredo Blakeley-Ruiz @alfredob.bsky.social
Reposted by Jee-Yon Lee
Gearing up vs the potential of building "mirror life"
A looming danger of bioengineered reversed-chirality bacteria and microbes.
www.science.org/doi/10.1126/... @science.org
A looming danger of bioengineered reversed-chirality bacteria and microbes.
www.science.org/doi/10.1126/... @science.org
Confronting risks of mirror life
Broad discussion is needed to chart a path forward.
www.science.org
December 12, 2024 at 7:41 PM
Gearing up vs the potential of building "mirror life"
A looming danger of bioengineered reversed-chirality bacteria and microbes.
www.science.org/doi/10.1126/... @science.org
A looming danger of bioengineered reversed-chirality bacteria and microbes.
www.science.org/doi/10.1126/... @science.org
Reposted by Jee-Yon Lee
Glad to share our preprint 🏃 **LongTrack**: long read metagenomics-based precise tracking of bacterial strains (and their genomic changes!) after 💩 fecal microbiota transplantation. A 4+ years journey and tour de force by ** @yufan01.bsky.social ** & team. A long 🧵 www.biorxiv.org/content/10.1...
December 11, 2024 at 1:51 PM
Glad to share our preprint 🏃 **LongTrack**: long read metagenomics-based precise tracking of bacterial strains (and their genomic changes!) after 💩 fecal microbiota transplantation. A 4+ years journey and tour de force by ** @yufan01.bsky.social ** & team. A long 🧵 www.biorxiv.org/content/10.1...
Reposted by Jee-Yon Lee
"Combinatorial, additive and dose-dependent drug–microbiome associations" by @inanna-nalytica.bsky.social investigates data from patients with cardiovascular disease within the MetaCardis consortium to disentangle the effect of drug combinations and other confounders (2021)
www.nature.com/artic...
www.nature.com/artic...
Combinatorial, additive and dose-dependent drug–microbiome associations
Nature - An analysis of 2,173 individuals from the MetaCardis cohort quantifies the individual and combinatorial effects of a range of drugs on host health, metabolome and gut microbiome in...
www.nature.com
December 8, 2024 at 2:00 PM
"Combinatorial, additive and dose-dependent drug–microbiome associations" by @inanna-nalytica.bsky.social investigates data from patients with cardiovascular disease within the MetaCardis consortium to disentangle the effect of drug combinations and other confounders (2021)
www.nature.com/artic...
www.nature.com/artic...
Reposted by Jee-Yon Lee
Resistance to one antibiotic can make bacteria resistant or sensitive to another antibiotic, opening paths for combinatorial treatments. A study in Nature Microbiology presents an approach to systematically discover and understand such antibiotic relationships. https://go.nature.com/49of3Mk 🧪
December 7, 2024 at 4:42 PM
Resistance to one antibiotic can make bacteria resistant or sensitive to another antibiotic, opening paths for combinatorial treatments. A study in Nature Microbiology presents an approach to systematically discover and understand such antibiotic relationships. https://go.nature.com/49of3Mk 🧪
Reposted by Jee-Yon Lee
A study in Scientific Reports finds that both high fruit and high vegetable intake were associated with lower depressive symptoms in people over 45 years old. Only moderate vegetable intakes were associated with lower depressive symptoms. https://go.nature.com/3ZDOIGL 🧪
December 7, 2024 at 3:11 PM
A study in Scientific Reports finds that both high fruit and high vegetable intake were associated with lower depressive symptoms in people over 45 years old. Only moderate vegetable intakes were associated with lower depressive symptoms. https://go.nature.com/3ZDOIGL 🧪
Reposted by Jee-Yon Lee
How Lactiplantibacillus plantarum specifically recognizes the fruit fly foregut as a distinct physical niche?
Cool paper on host-microbiota interaction in @science.org : www.science.org/doi/10.1126/....
And a nice summary, aptly titled ‘Home Sweet Home’: www.science.org/doi/10.1126/...
Cool paper on host-microbiota interaction in @science.org : www.science.org/doi/10.1126/....
And a nice summary, aptly titled ‘Home Sweet Home’: www.science.org/doi/10.1126/...
A conserved bacterial genetic basis for commensal-host specificity
Animals selectively acquire specific symbiotic gut bacteria from their environments that aid host fitness. To colonize, a symbiont must locate its niche and sustain growth within the gut. Adhesins are...
www.science.org
December 7, 2024 at 7:32 PM
How Lactiplantibacillus plantarum specifically recognizes the fruit fly foregut as a distinct physical niche?
Cool paper on host-microbiota interaction in @science.org : www.science.org/doi/10.1126/....
And a nice summary, aptly titled ‘Home Sweet Home’: www.science.org/doi/10.1126/...
Cool paper on host-microbiota interaction in @science.org : www.science.org/doi/10.1126/....
And a nice summary, aptly titled ‘Home Sweet Home’: www.science.org/doi/10.1126/...
Reposted by Jee-Yon Lee
New paper:
We show that population exposure to colibactin producing E. coli lineages ST95 and ST73 largely explains global variation in colorectal cancer incidence. Same STs are also major causes of UTIs and may be similarly involved in urinary tract cancers.
www.sciencedirect.com/science/arti...
We show that population exposure to colibactin producing E. coli lineages ST95 and ST73 largely explains global variation in colorectal cancer incidence. Same STs are also major causes of UTIs and may be similarly involved in urinary tract cancers.
www.sciencedirect.com/science/arti...
Geographical variation in the incidence of colorectal cancer and urinary tract cancer is associated with population exposure to colibactin-producing Escherichia coli
Biomedical research has implicated the bacterial metabolite colibactin as a causal risk factor for several cancer types, in particular, colorectal can…
www.sciencedirect.com
December 5, 2024 at 9:04 AM
New paper:
We show that population exposure to colibactin producing E. coli lineages ST95 and ST73 largely explains global variation in colorectal cancer incidence. Same STs are also major causes of UTIs and may be similarly involved in urinary tract cancers.
www.sciencedirect.com/science/arti...
We show that population exposure to colibactin producing E. coli lineages ST95 and ST73 largely explains global variation in colorectal cancer incidence. Same STs are also major causes of UTIs and may be similarly involved in urinary tract cancers.
www.sciencedirect.com/science/arti...
Thrilled to share my latest research paper! It reveals how a high-fat diet may induce prolonged sorbitol intolerance following antibiotic-induced microbial depletion.
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
High fat intake sustains sorbitol intolerance after antibiotic-mediated Clostridia depletion from the gut microbiota
A history of antibiotics in mice on a high-fat diet triggered sorbitol intolerance
by reducing Clostridia abundance, which could be treated with abundant sorbitol-consuming
probiotics.
www.cell.com
February 17, 2024 at 7:53 PM
Thrilled to share my latest research paper! It reveals how a high-fat diet may induce prolonged sorbitol intolerance following antibiotic-induced microbial depletion.
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...