Jay Singh
jayendra.bsky.social
Jay Singh
@jayendra.bsky.social
PhD student in Vasanthakumar lab @petermaccc.bsky.social, Melbourne
Interested in studying the Immune System.
Reposted by Jay Singh
Bluetorial: What’s the worst that can happen? Meeting a scientific hero

(Lots of chemical history today)
a cartoon says hey everybody an old man 's talking while bart simpson looks on
ALT: a cartoon says hey everybody an old man 's talking while bart simpson looks on
media.tenor.com
December 10, 2024 at 11:59 AM
Reposted by Jay Singh
New review article written by Cristhiane Favero de Aguiar and Carrie Corkish from my lab. They did a great job.

www.nature.com/articles/s41...

#SingleCell #Immunometabolism
#ImmunoSky

Approaches to investigate tissue-resident innate lymphocytes metabolism at the single-cell level
November 30, 2024 at 11:00 PM
Reposted by Jay Singh
REVIEW: Approaches to investigate tissue-resident innate lymphocytes metabolism at the single-cell level
www.nature.com/articles/s41...
@davidfinlaytcd.bsky.social
December 1, 2024 at 3:26 AM
Reposted by Jay Singh
My friend & colleague @micsysecolab.bsky.social Matthias has written this extremely insightful and fascinating perspective on bacterial collective metabolism, out now in @naturemicrobiol.bsky.social. So happy to see this out & super excited for proteome allocation! www.nature.com/articles/s41...
A framework for understanding collective microbiome metabolism - Nature Microbiology
This Perspective explores why microbiome members perform partial metabolism of substrates and suggests that proteome efficiency is a driver of collective microbiome metabolism.
www.nature.com
November 26, 2024 at 10:49 AM
Reposted by Jay Singh
Excellent discussion here about recent #glycotime study from @virusesimmunity.bsky.social and coworkers and the implications of the viral "GlcNAc" signature
I have been reading this super work ⬇️ with great interest and much enthusiasm as it discusses Ab recognition of viral glycosylation, but I don't understand how terminal GlcNAc can be a viral 'feature' as it corresponds to a stumpy human N-glycan... 1/3 #glycotime www.science.org/doi/10.1126/...
A B cell screen against endogenous retroviruses identifies glycan-reactive IgM that recognizes a broad array of enveloped viruses
Profiling of ERV-reactive B-1 cells in mice reveals natural antibodies against terminal N-acetylglucosamine on multiple viral envelope proteins.
www.science.org
November 22, 2024 at 8:45 PM
Reposted by Jay Singh
We’ve jumped on board fully here on 🦋
A starter pack of those working on our favourite cell … the T cell 🥰🙈🥰

If you want an add let us know

go.bsky.app/8B5P25c
November 19, 2024 at 10:11 PM
Reposted by Jay Singh
A pan-family screen of nuclear receptors in immunocytes reveals ligand-dependent inflammasome control
www.cell.com/immunity/ful...
November 21, 2024 at 3:34 AM
Reposted by Jay Singh
And big-lab-group-think is a stifling influence. Last month I gave a talk at a local big pharma site and the director/host literally asked me “if [insert three big names of field] haven’t already thought of the idea you presented, how could it possibly be true/important?”
November 18, 2024 at 6:35 PM