James Barrett
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james-r-barrett.bsky.social
James Barrett
@james-r-barrett.bsky.social
Lucky to be a PDRA in @mackinderlab.bsky.social. Interested in all things pyrenoid and some things phase separated.

https://james-r-barrett.github.io/
Pinned
How does molecular valency shape condensate assembly and function? We used the CO2-fixing organelle in algae—the pyrenoid—to find out… 🧵

Preprint here!:
www.biorxiv.org/content/10.6...

@cellarchlab.com @phaips.vd.st @biologyatyork.bsky.social
#Rubisco #PhaseSeparation #Condensates #Pyrenoid
Reposted by James Barrett
We genetically disconnected starch from the matrix in the algal pyrenoid!

A saga1;saga2 double mutant lacks a starch sheath!

Our model: SAGA1 & SAGA2 locally initiate starch on the pyrenoid surface by enriching starch precursors.

🌞🦠🔬🔌👀

www.biorxiv.org/content/10.6...
February 1, 2026 at 6:17 PM
How does molecular valency shape condensate assembly and function? We used the CO2-fixing organelle in algae—the pyrenoid—to find out… 🧵

Preprint here!:
www.biorxiv.org/content/10.6...

@cellarchlab.com @phaips.vd.st @biologyatyork.bsky.social
#Rubisco #PhaseSeparation #Condensates #Pyrenoid
January 30, 2026 at 3:21 PM