Jake Scott, MD
@jakescottmd.bsky.social
Infection diseases doctor | Stanford Clinical Associate Professor
Focused on vaccines, data transparency, and antimicrobial stewardship.
Views my own.
Focused on vaccines, data transparency, and antimicrobial stewardship.
Views my own.
Pinned
Jake Scott, MD
@jakescottmd.bsky.social
· Sep 13
Why the Senate's 'Most Important Vaccine Study Ever' Was Never Published
The fatal flaws that made this study unpublishable
jakescottmd.substack.com
A US senate subcommittee was told this unpublished vaccine study was 'the most important ever.' Henry Ford Health now confirms why it was never published: it failed scientific standards.
Here's what's actually wrong with the study:
jakescottmd.substack.com/p/why-the-senates-most-important-vaccine
Here's what's actually wrong with the study:
jakescottmd.substack.com/p/why-the-senates-most-important-vaccine
Important finding from our systematic review:
For adults 65+, choosing the right flu vaccine makes a huge difference. A Danish study from the 2024/25 season found a 17 percentage point gap between high-dose and standard flu vaccines in preventing hospitalization.
🧵
www.nejm.org/doi/full/10....
For adults 65+, choosing the right flu vaccine makes a huge difference. A Danish study from the 2024/25 season found a 17 percentage point gap between high-dose and standard flu vaccines in preventing hospitalization.
🧵
www.nejm.org/doi/full/10....
Updated Evidence for Covid-19, RSV, and Influenza Vaccines for 2025–2026 | NEJM
Changes in the vaccine advisory process in the United States have disrupted immunization guidance, which reinforces the need for independent evidence review to inform decisions regarding immunizati...
www.nejm.org
November 7, 2025 at 10:44 PM
Important finding from our systematic review:
For adults 65+, choosing the right flu vaccine makes a huge difference. A Danish study from the 2024/25 season found a 17 percentage point gap between high-dose and standard flu vaccines in preventing hospitalization.
🧵
www.nejm.org/doi/full/10....
For adults 65+, choosing the right flu vaccine makes a huge difference. A Danish study from the 2024/25 season found a 17 percentage point gap between high-dose and standard flu vaccines in preventing hospitalization.
🧵
www.nejm.org/doi/full/10....
Reposted by Jake Scott, MD
Experts told me that it’s now the perfect time to get a flu shot. All vaccines take 2 weeks to take full effect (that’s how long it takes your body to make antibodies). Be protected before you get on the plane to travel for Thanksgiving.
share.google/b8tCoqrYiy9r...
share.google/b8tCoqrYiy9r...
What to know about flu shots in 2025: Side effects, vaccine ingredients and when to get it
This year’s doses protect against three strains of influenza: Two types of influenza A and one type of influenza B.
share.google
November 2, 2025 at 5:15 PM
Experts told me that it’s now the perfect time to get a flu shot. All vaccines take 2 weeks to take full effect (that’s how long it takes your body to make antibodies). Be protected before you get on the plane to travel for Thanksgiving.
share.google/b8tCoqrYiy9r...
share.google/b8tCoqrYiy9r...
My @cidrap.bsky.social Op-Ed: "Vaccine effectiveness and safety: What the numbers truly mean in 2025"
Our review provides extensive data on Covid-19, RSV, and flu, though interpreting these numbers requires understanding the distinct context surrounding each.
www.cidrap.umn.edu/covid-19/cid...
Our review provides extensive data on Covid-19, RSV, and flu, though interpreting these numbers requires understanding the distinct context surrounding each.
www.cidrap.umn.edu/covid-19/cid...
CIDRAP Op-Ed: Vaccine effectiveness and safety: What the numbers truly mean in 2025
urldefense.com
October 31, 2025 at 7:53 PM
My @cidrap.bsky.social Op-Ed: "Vaccine effectiveness and safety: What the numbers truly mean in 2025"
Our review provides extensive data on Covid-19, RSV, and flu, though interpreting these numbers requires understanding the distinct context surrounding each.
www.cidrap.umn.edu/covid-19/cid...
Our review provides extensive data on Covid-19, RSV, and flu, though interpreting these numbers requires understanding the distinct context surrounding each.
www.cidrap.umn.edu/covid-19/cid...
Reposted by Jake Scott, MD
CIDRAP Op-Ed: Vaccine effectiveness and safety: What the numbers truly mean in 2025
Our systematic rvw published this week shows that rigorous, transparent evidence synthesis can persist even when traditional advisory processes falter
by Jake Scott, MD
www.cidrap.umn.edu/c...
Our systematic rvw published this week shows that rigorous, transparent evidence synthesis can persist even when traditional advisory processes falter
by Jake Scott, MD
www.cidrap.umn.edu/c...
October 31, 2025 at 7:20 PM
CIDRAP Op-Ed: Vaccine effectiveness and safety: What the numbers truly mean in 2025
Our systematic rvw published this week shows that rigorous, transparent evidence synthesis can persist even when traditional advisory processes falter
by Jake Scott, MD
www.cidrap.umn.edu/c...
Our systematic rvw published this week shows that rigorous, transparent evidence synthesis can persist even when traditional advisory processes falter
by Jake Scott, MD
www.cidrap.umn.edu/c...
HHS hasn't provided evidence for breaking up the MMR vaccine because none exists. As I wrote earlier this month, "No safety data justify abandoning a program that has protected millions of children for more than 50 years." @cidrap.bsky.social
www.cidrap.umn.edu/childhood-va...
www.cidrap.umn.edu/childhood-va...
CIDRAP Op-Ed: Why the CDC director is wrong about the MMR vaccine
www.cidrap.umn.edu
October 31, 2025 at 5:14 AM
HHS hasn't provided evidence for breaking up the MMR vaccine because none exists. As I wrote earlier this month, "No safety data justify abandoning a program that has protected millions of children for more than 50 years." @cidrap.bsky.social
www.cidrap.umn.edu/childhood-va...
www.cidrap.umn.edu/childhood-va...
NEW @nejm.org: We synthesized 511 recent studies on Covid-19, RSV & flu vaccines for 2025-26. With federal advisory processes disrupted, clinicians & the public need rigorous, independent evidence synthesis.
Here's what we found: 🧵
www.nejm.org/doi/full/10....
Here's what we found: 🧵
www.nejm.org/doi/full/10....
Updated Evidence for Covid-19, RSV, and Influenza Vaccines for 2025–2026 | NEJM
Changes in the vaccine advisory process in the United States have disrupted immunization
guidance, which reinforces the need for independent evidence review to inform decisions
regarding immunizati...
www.nejm.org
October 30, 2025 at 4:12 PM
NEW @nejm.org: We synthesized 511 recent studies on Covid-19, RSV & flu vaccines for 2025-26. With federal advisory processes disrupted, clinicians & the public need rigorous, independent evidence synthesis.
Here's what we found: 🧵
www.nejm.org/doi/full/10....
Here's what we found: 🧵
www.nejm.org/doi/full/10....
Reposted by Jake Scott, MD
Even as the anti-vax lobby erodes public trust, new evidence confirms that "immunizations against Covid-19, RSV, and influenza have shown consistent effectiveness & safety and are associated with a substantially reduced risk of hospitalization & severe disease"
www.nejm.org/doi/full/10....
www.nejm.org/doi/full/10....
October 29, 2025 at 11:15 PM
Even as the anti-vax lobby erodes public trust, new evidence confirms that "immunizations against Covid-19, RSV, and influenza have shown consistent effectiveness & safety and are associated with a substantially reduced risk of hospitalization & severe disease"
www.nejm.org/doi/full/10....
www.nejm.org/doi/full/10....
Thank you, @cidrap.bsky.social, for covering our new @nejm.org review of Covid-19, RSV, and influenza immunizations.
Check it out: cidrap.umn.edu/covid-19/meta-analysis-covid-rsv-flu-vaccines-fall-provides-sea-data-showing-efficacy-safety
Check it out: cidrap.umn.edu/covid-19/meta-analysis-covid-rsv-flu-vaccines-fall-provides-sea-data-showing-efficacy-safety
Meta-analysis of COVID, RSV, flu vaccines for fall provides 'sea of data' showing efficacy, safety
cidrap.umn.edu
October 30, 2025 at 1:37 AM
Thank you, @cidrap.bsky.social, for covering our new @nejm.org review of Covid-19, RSV, and influenza immunizations.
Check it out: cidrap.umn.edu/covid-19/meta-analysis-covid-rsv-flu-vaccines-fall-provides-sea-data-showing-efficacy-safety
Check it out: cidrap.umn.edu/covid-19/meta-analysis-covid-rsv-flu-vaccines-fall-provides-sea-data-showing-efficacy-safety
Reposted by Jake Scott, MD
Updated peer-reviewed evidence supports the safety and effectiveness of immunizations against Covid-19, RSV, and influenza during the 2025–2026 season @nejm.org @jakescottmd.bsky.social @stanforddeptmed.bsky.social
www.nejm.org/doi/full/10....
www.nejm.org/doi/full/10....
Updated Evidence for Covid-19, RSV, and Influenza Vaccines for 2025–2026 | NEJM
Changes in the vaccine advisory process in the United States have disrupted immunization
guidance, which reinforces the need for independent evidence review to inform decisions
regarding immunizati...
www.nejm.org
October 29, 2025 at 9:44 PM
Updated peer-reviewed evidence supports the safety and effectiveness of immunizations against Covid-19, RSV, and influenza during the 2025–2026 season @nejm.org @jakescottmd.bsky.social @stanforddeptmed.bsky.social
www.nejm.org/doi/full/10....
www.nejm.org/doi/full/10....
Trump’s proposing removal of aluminum salts from vaccines. Half of childhood vaccines rely on them (hep A/B, DTaP, Hib, HPV, meningo/pneumococcal). That change would take years, cost billions, and expose millions to preventable diseases despite zero evidence of harm.
www.nytimes.com/2025/10/15/h...
www.nytimes.com/2025/10/15/h...
Trump Rattles Vaccine Experts Over Aluminum
www.nytimes.com
October 16, 2025 at 2:40 AM
Trump’s proposing removal of aluminum salts from vaccines. Half of childhood vaccines rely on them (hep A/B, DTaP, Hib, HPV, meningo/pneumococcal). That change would take years, cost billions, and expose millions to preventable diseases despite zero evidence of harm.
www.nytimes.com/2025/10/15/h...
www.nytimes.com/2025/10/15/h...
Alarming report on FDA political interference. Scientists are being asked to find data supporting predetermined conclusions on autism treatments, vaccines, SSRIs - the opposite of how science works.
We need evidence-based regulation, not regulation-based evidence.
www.statnews.com/2025/10/14/f...
We need evidence-based regulation, not regulation-based evidence.
www.statnews.com/2025/10/14/f...
Inside FDA, career staffers describe how political pressure is influencing their work
Current and former FDA staff said the level of involvement of political officials in nitty-gritty regulatory matters is unprecedented.
www.statnews.com
October 14, 2025 at 6:16 PM
Alarming report on FDA political interference. Scientists are being asked to find data supporting predetermined conclusions on autism treatments, vaccines, SSRIs - the opposite of how science works.
We need evidence-based regulation, not regulation-based evidence.
www.statnews.com/2025/10/14/f...
We need evidence-based regulation, not regulation-based evidence.
www.statnews.com/2025/10/14/f...
Reposted by Jake Scott, MD
We’re once again ranked #1 among most-read U.S. nonprofit news sites, according to @niemanlab.org 👏
Our mission to share fact-based journalism keeps reaching new audiences .
We’re in great company on the list, which includes @propublica.org, @blockclubchi.bsky.social and other great nonprofits.
Our mission to share fact-based journalism keeps reaching new audiences .
We’re in great company on the list, which includes @propublica.org, @blockclubchi.bsky.social and other great nonprofits.
October 12, 2025 at 1:28 AM
We’re once again ranked #1 among most-read U.S. nonprofit news sites, according to @niemanlab.org 👏
Our mission to share fact-based journalism keeps reaching new audiences .
We’re in great company on the list, which includes @propublica.org, @blockclubchi.bsky.social and other great nonprofits.
Our mission to share fact-based journalism keeps reaching new audiences .
We’re in great company on the list, which includes @propublica.org, @blockclubchi.bsky.social and other great nonprofits.
Reposted by Jake Scott, MD
Some of these people have now been fired and rehired TWICE since January. The current state of dysfunction is mind boggling.
OOOPS! UPDATE: Two HHS officials tell me that disease detectives, measles response officers, global health officials and the MMWR staff were laid off by mistake and will be reinstated. But Washington office is still RIFed
BREAKING: Friday night massacre underway at CDC. Doznes of "disease detectives," high-level scientists, entire Washington staff and editors of the MMWR (Morbidity and Mortality Weekly Report) have all been RIFed and received the following notice:
October 12, 2025 at 1:14 AM
Some of these people have now been fired and rehired TWICE since January. The current state of dysfunction is mind boggling.
Reposted by Jake Scott, MD
The editors of the CDC’s Morbidity and Mortality Weekly Report (MMWR) were apparently fired today.
The precursor to MMWR began in 1878 to address emerging public health threats rapidly.
We are not “great” without it. We are vulnerable to threats from sporadic foodborne illness to bioterrorism.
The precursor to MMWR began in 1878 to address emerging public health threats rapidly.
We are not “great” without it. We are vulnerable to threats from sporadic foodborne illness to bioterrorism.
October 11, 2025 at 4:09 AM
The editors of the CDC’s Morbidity and Mortality Weekly Report (MMWR) were apparently fired today.
The precursor to MMWR began in 1878 to address emerging public health threats rapidly.
We are not “great” without it. We are vulnerable to threats from sporadic foodborne illness to bioterrorism.
The precursor to MMWR began in 1878 to address emerging public health threats rapidly.
We are not “great” without it. We are vulnerable to threats from sporadic foodborne illness to bioterrorism.
Reposted by Jake Scott, MD
CIDRAP Op-Ed: Why the CDC director is wrong about the MMR vaccine
by @jakescottMD
A call to develop separate measles, mumps, and rubella vaccines to replace the combined MMR shot is not backed by evidence. Here are the facts.
www.cidrap.umn.edu/c...
by @jakescottMD
A call to develop separate measles, mumps, and rubella vaccines to replace the combined MMR shot is not backed by evidence. Here are the facts.
www.cidrap.umn.edu/c...
October 9, 2025 at 4:24 PM
CIDRAP Op-Ed: Why the CDC director is wrong about the MMR vaccine
by @jakescottMD
A call to develop separate measles, mumps, and rubella vaccines to replace the combined MMR shot is not backed by evidence. Here are the facts.
www.cidrap.umn.edu/c...
by @jakescottMD
A call to develop separate measles, mumps, and rubella vaccines to replace the combined MMR shot is not backed by evidence. Here are the facts.
www.cidrap.umn.edu/c...
Reposted by Jake Scott, MD
“Secretary Kennedy is entitled to his views. But he is not entitled to put people’s health at risk.”
Six former surgeons general condemn RFK Jr.
Six former surgeons general condemn RFK Jr.
Opinion | Six surgeons general: RFK Jr. is a threat to the health of Americans
It was our duty in office to warn of dangers when we found them. We’re doing that again today.
www.washingtonpost.com
October 7, 2025 at 11:27 AM
“Secretary Kennedy is entitled to his views. But he is not entitled to put people’s health at risk.”
Six former surgeons general condemn RFK Jr.
Six former surgeons general condemn RFK Jr.
“We have 1,544 measles cases this year, 92% in unvaccinated people, and 3 deaths. The problem isn’t the vaccine — it’s that people aren’t getting it. O’Neill hasn’t offered a single scientific rationale for breaking up MMR.”
@aniloza.bsky.social
@statnews.com
www.statnews.com/2025/10/06/t...
@aniloza.bsky.social
@statnews.com
www.statnews.com/2025/10/06/t...
Acting CDC director calls for MMR vaccine to be broken up into three shots
There's no evidence that breaking up the MMR shot would make the immunization safer or more effective.
www.statnews.com
October 7, 2025 at 5:53 AM
“We have 1,544 measles cases this year, 92% in unvaccinated people, and 3 deaths. The problem isn’t the vaccine — it’s that people aren’t getting it. O’Neill hasn’t offered a single scientific rationale for breaking up MMR.”
@aniloza.bsky.social
@statnews.com
www.statnews.com/2025/10/06/t...
@aniloza.bsky.social
@statnews.com
www.statnews.com/2025/10/06/t...
Reposted by Jake Scott, MD
The Trump Action Tracker is a website designed by a British group that is cataloging all of the administration's actions, statements, and plans. It is a depressing but important read. Check it out at trumpactiontracker.info
October 5, 2025 at 8:52 PM
The Trump Action Tracker is a website designed by a British group that is cataloging all of the administration's actions, statements, and plans. It is a depressing but important read. Check it out at trumpactiontracker.info
Reposted by Jake Scott, MD
A study imagined NIH with 40% less funding. The result? More than half of FDA-approved drugs since 2000 might not exist. Basic research dollars have real-world impact.
buff.ly/CIfauh4
buff.ly/CIfauh4
Science costs money – research is guided by who funds it and why
The federal government is more likely to fund curiosity-driven basic research, while industry is more likely to support research that has a clearer eventual payoff.
buff.ly
October 5, 2025 at 9:04 PM
A study imagined NIH with 40% less funding. The result? More than half of FDA-approved drugs since 2000 might not exist. Basic research dollars have real-world impact.
buff.ly/CIfauh4
buff.ly/CIfauh4
Reposted by Jake Scott, MD
Six young children died, one facing amputation of limbs, all unvaccinated, all from measles.
Protect your children.
belaaz.com/news/11-mont...
Protect your children.
belaaz.com/news/11-mont...
11-Month-Old Charedi Baby Faces Amputation After Severe Measles Complications - Belaaz News
An 11-month-old infant from Beitar Illit, hospitalized at Hadassah Medical Center after contracting measles, is scheduled for surgery to amputate all four limbs due to necrosis, according to a Tuesday...
belaaz.com
October 4, 2025 at 4:55 PM
Six young children died, one facing amputation of limbs, all unvaccinated, all from measles.
Protect your children.
belaaz.com/news/11-mont...
Protect your children.
belaaz.com/news/11-mont...
The US needs to build an independent alternative to HHS, CDC, etc. We’ve been hijacked by an authoritarian with an ideological agenda, and no amount of evidence will convince him he’s dead wrong. There are brilliant scientists and doctors in this country and this is an all hands on deck crisis.
October 4, 2025 at 8:44 PM
The US needs to build an independent alternative to HHS, CDC, etc. We’ve been hijacked by an authoritarian with an ideological agenda, and no amount of evidence will convince him he’s dead wrong. There are brilliant scientists and doctors in this country and this is an all hands on deck crisis.
Reposted by Jake Scott, MD
She had a reputation for working with Republicans and Democrats alike. But @drdebhoury.bsky.social was never once able to brief RFK Jr. In fact, she only met him once — when he toured the empty CDC after a gunman killed Officer David Rose and traumatized staff.
www.theguardian.com/us-news/2025...
www.theguardian.com/us-news/2025...
A ‘hostile takeover’: ousted CDC official raises alarm over RFK Jr approach to infectious disease
Debra Houry speaks after testifying on eight months under Kennedy, who critics say shuns science and spreads falsehoods
www.theguardian.com
October 4, 2025 at 8:12 PM
She had a reputation for working with Republicans and Democrats alike. But @drdebhoury.bsky.social was never once able to brief RFK Jr. In fact, she only met him once — when he toured the empty CDC after a gunman killed Officer David Rose and traumatized staff.
www.theguardian.com/us-news/2025...
www.theguardian.com/us-news/2025...
Reposted by Jake Scott, MD
