Jacob (Yaqub) Hanna - يعقوب حنا
@jacob-hanna.bsky.social
Palestinian Stem Cell Scientist. Palestinian and LQBTQ+ rights advocate. #Arab&BlackLivesMatter #EndOccupation #FreePalestine #PeaceNOW #CeasefireNOW #BringThemHomeNow! Personal account.
1936. Must see film by the talented Annemarie Jacir. A remarkable film abt 1936 Palestinian Revolt against British colonialism. One of the best depictions of revolution filmed. Audience broke into chanting "Free Free Palestine" at the end. #FreePalestine #PeaceNow
www.youtube.com/watch?v=wWtw...
www.youtube.com/watch?v=wWtw...
PALESTINE 36 | Official UK Trailer - In Cinemas 31 October
YouTube video by Curzon
www.youtube.com
November 23, 2025 at 4:43 PM
1936. Must see film by the talented Annemarie Jacir. A remarkable film abt 1936 Palestinian Revolt against British colonialism. One of the best depictions of revolution filmed. Audience broke into chanting "Free Free Palestine" at the end. #FreePalestine #PeaceNow
www.youtube.com/watch?v=wWtw...
www.youtube.com/watch?v=wWtw...
Looking forward for this meeting .. my talk much less :), but i am using this reposting to promote this great meeting in Berlin! for those who haven't registered yet.
🧬📢 We look forward to welcoming Jacob Hanna from the Weizmann Institute of Science as part of our speaker lineup for the #Embryo2026 meeting!
More information 👇
www.molgen.mpg.de/embryo2026
More information 👇
www.molgen.mpg.de/embryo2026
November 10, 2025 at 1:31 PM
Looking forward for this meeting .. my talk much less :), but i am using this reposting to promote this great meeting in Berlin! for those who haven't registered yet.
MIT Technology Review article about our research on human embryo models in this day & age.
I didn't agree to interview because what i find as over-sensational writing style & i disagree with several things..
BUT Antonio managed to put together an interesting mix of events and ideas worth reading.
I didn't agree to interview because what i find as over-sensational writing style & i disagree with several things..
BUT Antonio managed to put together an interesting mix of events and ideas worth reading.
The astonishing science of synthetic embryology and our profile of it's most ambitious praticioner, Jacob Hanna
www.technologyreview.com/2025/10/21/1...
www.technologyreview.com/2025/10/21/1...
The astonishing embryo models of Jacob Hanna
Scientists are creating the beginnings of bodies without sperm or eggs. How far should they be allowed to go?
www.technologyreview.com
October 25, 2025 at 9:05 PM
MIT Technology Review article about our research on human embryo models in this day & age.
I didn't agree to interview because what i find as over-sensational writing style & i disagree with several things..
BUT Antonio managed to put together an interesting mix of events and ideas worth reading.
I didn't agree to interview because what i find as over-sensational writing style & i disagree with several things..
BUT Antonio managed to put together an interesting mix of events and ideas worth reading.
A Palestinian, son of Palestinians displaced from Gaza (Al-Masmiyya) to Jordan, wins the Nobel Prize in Chemistry... Professor Omar Munis Yaghi from the University of Berkeley!!
..Some members of the Yaghi family are still under the rubble in Gaza!
..Some members of the Yaghi family are still under the rubble in Gaza!
October 8, 2025 at 11:25 AM
A Palestinian, son of Palestinians displaced from Gaza (Al-Masmiyya) to Jordan, wins the Nobel Prize in Chemistry... Professor Omar Munis Yaghi from the University of Berkeley!!
..Some members of the Yaghi family are still under the rubble in Gaza!
..Some members of the Yaghi family are still under the rubble in Gaza!
Reposted by Jacob (Yaqub) Hanna - يعقوب حنا
Transgene-free generation of mouse post-gastrulation whole embryo models solely from naive ESCs and iPSCs
Transgene-free generation of mouse post-gastrulation whole embryo models solely from naive ESCs and iPSCs
Hanna and colleagues show that signaling pathway modulation amplifies the inherent flexibility of genetically unmodified mouse naive PSCs to adopt extra-embryonic cell fate potential. This endows them with the competence to generate up to E8.5–E8.75 transgene-free stem cell-derived embryo models (TF-SEMs) that complete gastrulation and initiate organogenesis within complex extra-embryonic compartments ex utero.
dlvr.it
October 2, 2025 at 4:00 PM
Transgene-free generation of mouse post-gastrulation whole embryo models solely from naive ESCs and iPSCs
Reposted by Jacob (Yaqub) Hanna - يعقوب حنا
Building the start: Unlocking advanced stem cell-based embryo models
Building the start: Unlocking advanced stem cell-based embryo models
Two recent studies from the Silva and Hanna groups optimized chemical induction and culture conditions to derive extraembryonic lineages directly from embryonic stem cells (ESCs) without transgenes, enabling mouse stem cell-based embryo models (SCBEMs) to reproducibly advance to the E8.5–E8.75 stage.
dlvr.it
October 7, 2025 at 2:10 PM
Building the start: Unlocking advanced stem cell-based embryo models
Last day of intense science discussions and presentations at the HFSP Science Summit Japan was held in Kyoto university. It has been an amazing 5 days of listening to great scientists from Japan and all over the world. An unforgettable visit.
🧪 The #HFSPSummitJapan ended today in Kyoto
✨ Nobel Laureates & Nakasone Awardees shared insights with young researchers
🧬 Svante Pääbo gave a fascinating keynote on human evolution.
👩🔬 A lively poster session closed the day.
What a journey! What a Summit! More highlights soon 🙂
#sts
✨ Nobel Laureates & Nakasone Awardees shared insights with young researchers
🧬 Svante Pääbo gave a fascinating keynote on human evolution.
👩🔬 A lively poster session closed the day.
What a journey! What a Summit! More highlights soon 🙂
#sts
October 4, 2025 at 12:15 PM
Last day of intense science discussions and presentations at the HFSP Science Summit Japan was held in Kyoto university. It has been an amazing 5 days of listening to great scientists from Japan and all over the world. An unforgettable visit.
Thanks to Leqian Yu and co and @cp-cellstemcell.bsky.social for highlighting recent work, including ours, on transgene free mouse high fidelity post gastrulation SEMs www.cell.com/cell-stem-ce...
Building the start: Unlocking advanced stem cell-based embryo models
Two recent studies from the Silva and Hanna groups optimized chemical induction and
culture conditions to derive extraembryonic lineages directly from embryonic stem
cells (ESCs) without transgenes, e...
www.cell.com
October 4, 2025 at 12:10 AM
Thanks to Leqian Yu and co and @cp-cellstemcell.bsky.social for highlighting recent work, including ours, on transgene free mouse high fidelity post gastrulation SEMs www.cell.com/cell-stem-ce...
Another great day in Japan science summit with Intriguing science and science policy discussions at University of Tokyo.
🧪 The #HFSPSummitJapan High-Level Event has started at The University of Tokyo 🇯🇵!
Nobel Laureates, Science Leaders, HFSP Nakasone Awardees & Japanese researchers debating innovation, collaboration, and the future of life sciences. 🌟 #HFSPsciencesummit #sts
Nobel Laureates, Science Leaders, HFSP Nakasone Awardees & Japanese researchers debating innovation, collaboration, and the future of life sciences. 🌟 #HFSPsciencesummit #sts
October 3, 2025 at 6:50 AM
Another great day in Japan science summit with Intriguing science and science policy discussions at University of Tokyo.
Finally .. incredible much awaited wok on deriving avian naive ESCs
“Derivation of embryonic stem cells across avian species”
www.nature.com/articles/s41...
“Derivation of embryonic stem cells across avian species”
www.nature.com/articles/s41...
Derivation of embryonic stem cells across avian species - Nature Biotechnology
Embryonic stem cells for chicken and seven other avian species are derived.
www.nature.com
October 3, 2025 at 2:18 AM
Finally .. incredible much awaited wok on deriving avian naive ESCs
“Derivation of embryonic stem cells across avian species”
www.nature.com/articles/s41...
“Derivation of embryonic stem cells across avian species”
www.nature.com/articles/s41...
This was a real fun event!
🧪 The HFSP Science Summit Japan has officially kicked off today at Tohoku University in Sendai! An inspiring start with outstanding researchers & young scientists reflecting on collaboration and innovation in life sciences. 🌍✨ #sts #HFSPSummitJapan
October 1, 2025 at 9:33 AM
This was a real fun event!
EEE meeting is BACK! Early Embryogenesis & Epigenetics conference in Berlin 02/2026.
Checkout great program and over 12 slots for (not so) short talks for submitted abstracts!. Early registration now open -
w.molgen.mpg.de/embryo2026
Checkout great program and over 12 slots for (not so) short talks for submitted abstracts!. Early registration now open -
w.molgen.mpg.de/embryo2026
September 28, 2025 at 12:00 AM
EEE meeting is BACK! Early Embryogenesis & Epigenetics conference in Berlin 02/2026.
Checkout great program and over 12 slots for (not so) short talks for submitted abstracts!. Early registration now open -
w.molgen.mpg.de/embryo2026
Checkout great program and over 12 slots for (not so) short talks for submitted abstracts!. Early registration now open -
w.molgen.mpg.de/embryo2026
Reposted by Jacob (Yaqub) Hanna - يعقوب حنا
Having fun @amartinezarias.bsky.social party! 🙏🏻🎉💐 Great meeting #InHoxWeSortOfTrust
September 19, 2025 at 7:59 PM
Having fun @amartinezarias.bsky.social party! 🙏🏻🎉💐 Great meeting #InHoxWeSortOfTrust
Reposted by Jacob (Yaqub) Hanna - يعقوب حنا
🧪 HFSP & partners present Science Summit Japan 2025!
🗓️Oct 1–4 📍Tohoku University, RIKEN, UThe University of Tokyo & Kyoto University.
✨ Nobel Laureates, HFSP Nakasone Awardees & top researchers engaging with young scientists.
More info 👉https://bit.ly/45WGRWM
🗓️Oct 1–4 📍Tohoku University, RIKEN, UThe University of Tokyo & Kyoto University.
✨ Nobel Laureates, HFSP Nakasone Awardees & top researchers engaging with young scientists.
More info 👉https://bit.ly/45WGRWM
September 3, 2025 at 9:40 AM
🧪 HFSP & partners present Science Summit Japan 2025!
🗓️Oct 1–4 📍Tohoku University, RIKEN, UThe University of Tokyo & Kyoto University.
✨ Nobel Laureates, HFSP Nakasone Awardees & top researchers engaging with young scientists.
More info 👉https://bit.ly/45WGRWM
🗓️Oct 1–4 📍Tohoku University, RIKEN, UThe University of Tokyo & Kyoto University.
✨ Nobel Laureates, HFSP Nakasone Awardees & top researchers engaging with young scientists.
More info 👉https://bit.ly/45WGRWM
Shout out re @isscr.org awards nomination deadline SEP 30 2025! Please note the great revision & efforts that have been made to recognize excellence in industry, policy makers, clinical translation etc & from across the globe. Self-nominations are equally welcomed!
www.isscr.org/awards
www.isscr.org/awards
Awards + Nominations — International Society for Stem Cell Research
The ISSCR Awards portfolio recognizes outstanding achievements and research potential in the field of stem cell research around the world. The ISSCR awards honor scientists’ innovative work to harness...
www.isscr.org
August 28, 2025 at 11:50 AM
Shout out re @isscr.org awards nomination deadline SEP 30 2025! Please note the great revision & efforts that have been made to recognize excellence in industry, policy makers, clinical translation etc & from across the globe. Self-nominations are equally welcomed!
www.isscr.org/awards
www.isscr.org/awards
Reposted by Jacob (Yaqub) Hanna - يعقوب حنا
Pathway to Independence – an interview with Joaquín Navajas Acedo.
In this interview, @mads100tist.bsky.social talks about about his research vision, zebrafish and the importance of community:
journals.biologists.com/dev/article/...
In this interview, @mads100tist.bsky.social talks about about his research vision, zebrafish and the importance of community:
journals.biologists.com/dev/article/...
August 15, 2025 at 3:47 PM
Pathway to Independence – an interview with Joaquín Navajas Acedo.
In this interview, @mads100tist.bsky.social talks about about his research vision, zebrafish and the importance of community:
journals.biologists.com/dev/article/...
In this interview, @mads100tist.bsky.social talks about about his research vision, zebrafish and the importance of community:
journals.biologists.com/dev/article/...
Tnx to @hfspo.bsky.social for humbling opportunity to present our work #HFSPNakasoneAward lecture.
Tnx to Hanna lab, current & former members, collaborators, mentors. @weizmanninstitute.bsky.social for critical backing, @isscr.org for guidelines, funding agencies & dear philanthropists for funding
Tnx to Hanna lab, current & former members, collaborators, mentors. @weizmanninstitute.bsky.social for critical backing, @isscr.org for guidelines, funding agencies & dear philanthropists for funding
🧪 From petri dish to embryo model: @jacob-hanna.bsky.social work shows how naïve pluripotent stem cells can self-organize into advanced developmental stages.
The 2025 #HFSPNakasoneAward lecture reveals the science behind synthetic embryo models.
Full lecture 🎥 👉 zurl.co/Tgf4f
#sts
The 2025 #HFSPNakasoneAward lecture reveals the science behind synthetic embryo models.
Full lecture 🎥 👉 zurl.co/Tgf4f
#sts
HFSP Nakasone Award 2025 Lecture – Jacob Hanna on Synthetic Embryo Models
In this official HFSP Nakasone Award lecture, Professor Jacob (Yaqub) Hanna of the Weizmann Institute of Science shares the groundbreaking research that earn...
www.youtube.com
August 14, 2025 at 11:59 AM
Tnx to @hfspo.bsky.social for humbling opportunity to present our work #HFSPNakasoneAward lecture.
Tnx to Hanna lab, current & former members, collaborators, mentors. @weizmanninstitute.bsky.social for critical backing, @isscr.org for guidelines, funding agencies & dear philanthropists for funding
Tnx to Hanna lab, current & former members, collaborators, mentors. @weizmanninstitute.bsky.social for critical backing, @isscr.org for guidelines, funding agencies & dear philanthropists for funding
Reposted by Jacob (Yaqub) Hanna - يعقوب حنا
🤩 Very excited to share our new work! We have derived euploid and aneuploid trophoblast organoids and extra-embryonic mesoderm cell lines from early human embryos. In doing so, we have characterised the tissue requirements for their specification. If you want to know more, continue reading….
August 9, 2025 at 8:03 AM
🤩 Very excited to share our new work! We have derived euploid and aneuploid trophoblast organoids and extra-embryonic mesoderm cell lines from early human embryos. In doing so, we have characterised the tissue requirements for their specification. If you want to know more, continue reading….
1/n Fun journey continues: Our new @cp-cellstemcell.bsky.social paper out on how the Inherent & Dormant Plasticity of Mouse Naive PSCs can be "Exaggerated" to Directly form ~E8.5 Transgene-Free (TF) Mouse SEMs & WITHOUT inducing 8-16-Morula-like "Embryo Founder Cells".
www.cell.com/cell-stem-ce...
www.cell.com/cell-stem-ce...
Transgene-free generation of mouse post-gastrulation whole embryo models solely from naive ESCs and iPSCs
Hanna and colleagues show that signaling pathway modulation amplifies the inherent
flexibility of genetically unmodified mouse naive PSCs to adopt extra-embryonic cell
fate potential. This endows them...
www.cell.com
August 7, 2025 at 3:29 PM
1/n Fun journey continues: Our new @cp-cellstemcell.bsky.social paper out on how the Inherent & Dormant Plasticity of Mouse Naive PSCs can be "Exaggerated" to Directly form ~E8.5 Transgene-Free (TF) Mouse SEMs & WITHOUT inducing 8-16-Morula-like "Embryo Founder Cells".
www.cell.com/cell-stem-ce...
www.cell.com/cell-stem-ce...
Reposted by Jacob (Yaqub) Hanna - يعقوب حنا
To have this paper appear the same day that RFK Jr is canceling all mRNA vaccine funding is further indication that irony is not dead, even though we might all be soon.
August 6, 2025 at 12:35 AM
To have this paper appear the same day that RFK Jr is canceling all mRNA vaccine funding is further indication that irony is not dead, even though we might all be soon.
1/n Dear friends, in light of the current events in Palestine and to help spread awareness, a large number of filmmakers have made their FILMS about PALESTINE AVAILABLE FOR ONLINE FOR FREE
Below, we are sharing links to films that you can watch and share to spread our message to the world:
Below, we are sharing links to films that you can watch and share to spread our message to the world:
August 5, 2025 at 10:37 PM
1/n Dear friends, in light of the current events in Palestine and to help spread awareness, a large number of filmmakers have made their FILMS about PALESTINE AVAILABLE FOR ONLINE FOR FREE
Below, we are sharing links to films that you can watch and share to spread our message to the world:
Below, we are sharing links to films that you can watch and share to spread our message to the world:
Reposted by Jacob (Yaqub) Hanna - يعقوب حنا
1/n Very excited to share our recent paper published on
@ScienceAdvances
where we dissect the gene regulatory landscape guiding mouse sex determination!
science.org/doi/10.1126/...
A huge well done to @IsabelleStevant.genomic.social.ap.brid.gy, Meshi and Elisheva who spearhead this project!
@ScienceAdvances
where we dissect the gene regulatory landscape guiding mouse sex determination!
science.org/doi/10.1126/...
A huge well done to @IsabelleStevant.genomic.social.ap.brid.gy, Meshi and Elisheva who spearhead this project!
The gene regulatory landscape driving mouse gonadal supporting cell differentiation
Multiomics analysis revealed the regulatory elements and transcription factors responsible for gonadal sex determination.
science.org
July 27, 2025 at 6:04 AM
1/n Very excited to share our recent paper published on
@ScienceAdvances
where we dissect the gene regulatory landscape guiding mouse sex determination!
science.org/doi/10.1126/...
A huge well done to @IsabelleStevant.genomic.social.ap.brid.gy, Meshi and Elisheva who spearhead this project!
@ScienceAdvances
where we dissect the gene regulatory landscape guiding mouse sex determination!
science.org/doi/10.1126/...
A huge well done to @IsabelleStevant.genomic.social.ap.brid.gy, Meshi and Elisheva who spearhead this project!
Reposted by Jacob (Yaqub) Hanna - يعقوب حنا
Fascinating story today from @levfacher.bsky.social about a rehab center where patients are currently being treated for substance use disorder with GLP-1 drugs — even as clinical trials measuring their effectiveness as anti-addiction medications remain years from reading out data.
New: Inside the elite Pennsylvania rehab facility aggressively prescribing GLP-1s, normally used for weight loss, as medications to treat addiction
“I truly think these medications work because obesity is an addiction to food.”
www.statnews.com/2025/07/14/g...
“I truly think these medications work because obesity is an addiction to food.”
www.statnews.com/2025/07/14/g...
Ozempic for addiction: How an elite rehab center is using GLP-1s to 'obliterate' all kinds of cravings
Pointing to Ozempic as a paradigm shift, an elite rehab center is experimenting with GLP-1s to tame many forms of addiction.
www.statnews.com
July 14, 2025 at 7:11 PM
Fascinating story today from @levfacher.bsky.social about a rehab center where patients are currently being treated for substance use disorder with GLP-1 drugs — even as clinical trials measuring their effectiveness as anti-addiction medications remain years from reading out data.
Reposted by Jacob (Yaqub) Hanna - يعقوب حنا
Neuron programming! Pro-neural TFs + 480 morphogen conditions + scRNA-seq --> Diverse iN subtypes of forebrain, midbrain, hindbrain, spinal cord, and PNS. @hsiuchuanlin.bsky.social @jasperjanssens.bsky.social and Treutlein Lab! @science.org www.science.org/doi/10.1126/... #NGN2 #ASCL1
July 11, 2025 at 8:59 PM
Neuron programming! Pro-neural TFs + 480 morphogen conditions + scRNA-seq --> Diverse iN subtypes of forebrain, midbrain, hindbrain, spinal cord, and PNS. @hsiuchuanlin.bsky.social @jasperjanssens.bsky.social and Treutlein Lab! @science.org www.science.org/doi/10.1126/... #NGN2 #ASCL1
Reposted by Jacob (Yaqub) Hanna - يعقوب حنا
I was interviewed recently by @stemcellpodcast.com
I witter on about morphogens, notochord, @dev-journal.bsky.social & how biology is becoming a data science
Thanks @stemcellpodcast.com for talking to me
stemcellpodcast.com/ep-299-spina...
I witter on about morphogens, notochord, @dev-journal.bsky.social & how biology is becoming a data science
Thanks @stemcellpodcast.com for talking to me
stemcellpodcast.com/ep-299-spina...
Ep. 299: "Spinal Cord Development" Featuring Dr. James Briscoe - The Stem Cell Podcast
Dr. James Briscoe is a Group Leader at the Francis Crick Institute and Editor-In-Chief of Development. His lab uses an interdisciplinary approach, including mice, chicks, and other models, to study de...
stemcellpodcast.com
July 9, 2025 at 8:00 AM
I was interviewed recently by @stemcellpodcast.com
I witter on about morphogens, notochord, @dev-journal.bsky.social & how biology is becoming a data science
Thanks @stemcellpodcast.com for talking to me
stemcellpodcast.com/ep-299-spina...
I witter on about morphogens, notochord, @dev-journal.bsky.social & how biology is becoming a data science
Thanks @stemcellpodcast.com for talking to me
stemcellpodcast.com/ep-299-spina...