Hugo Talibart
hugotalibart.bsky.social
Hugo Talibart
@hugotalibart.bsky.social
Postdoctoral researcher in bioinformatics at Université Libre de Bruxelles. Proteins, (co-)evolution, drug design, AI (-skeptic). Computer geek, python enthousiast. 🏳️‍🌈
Matsvei Tsishyn will also be there at poster A-063 to present our work (mostly his): StructureDCA, "Inferring Protein Mutational Landscape with Structure-Informed Direct Coupling Analysis"

#ISMBECCB2025 #3DSIG
July 20, 2025 at 9:15 PM
See you tomorrow, poster B-443! #ISMBECCB2025
July 20, 2025 at 9:10 PM
And that's the goal of my current research: design new molecules that target some specific olfactory receptors.

And that's a challenge... more on that later! :)
May 24, 2025 at 1:45 PM
Interestingly, olfactory receptors aren’t limited to the nose: they’re also expressed in various tissues where they regulate different functions (blood pressure, glucose metabolism, hair growth, even play a role in prostate cancer...)...

which makes them promising drug targets!
May 24, 2025 at 1:45 PM
Olfaction works like a combinatorial code: there are various types of olfactory receptors, each can be activated by multiple molecules, and some molecules can activate multiple receptors. The brain interprets these unique activation patterns as distinct smells.
May 24, 2025 at 1:45 PM