Sarah Hedtrich
@hedtrichlab.bsky.social
Prof@UBC SBME, Canada Research Chair, mom of 2, interested in next-generation therapies, nanomedicine & bioengineering. Posts are my own. Advocate for #WomenInScience
Reposted by Sarah Hedtrich
Combining a base editor, transient barrier modulation, and topical mRNA-lipid nanoparticle administration to restore clinically meaningful levels of transglutaminase 1 activity @cp-cellstemcell.bsky.social @hedtrichlab.bsky.social
www.cell.com/cell-stem-ce...
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February 5, 2026 at 9:37 PM
Combining a base editor, transient barrier modulation, and topical mRNA-lipid nanoparticle administration to restore clinically meaningful levels of transglutaminase 1 activity @cp-cellstemcell.bsky.social @hedtrichlab.bsky.social
www.cell.com/cell-stem-ce...
www.cell.com/cell-stem-ce...
www.cell.com/cell-stem-ce...
www.cell.com/cell-stem-ce...
Reposted by Sarah Hedtrich
Online Now! Lipid nanoparticle-based non-viral in situ gene editing of congenital ichthyosis-causing mutations in human skin models #stemcells
Lipid nanoparticle-based non-viral in situ gene editing of congenital ichthyosis-causing mutations in human skin models
Hedtrich and colleagues developed a topical, laser-assisted LNP approach to deliver gene editors into human skin. Their method corrects a disease-causing TGM1 mutation in ARCI models, restores TG1 function, and shows excellent safety, highlighting a minimally invasive strategy for treating severe genetic skin disorders.
dlvr.it
January 27, 2026 at 8:09 PM
Online Now! Lipid nanoparticle-based non-viral in situ gene editing of congenital ichthyosis-causing mutations in human skin models #stemcells
Super proud of this work from my lab that has great translational potential and can fundamentally change how we treat skin diseases.
Bringing CRISPR to the skin: UBC scientists have developed a topical gene-editing treatment that could transform how we treat skin conditions like eczema, psoriasis and rare diseases. ⤵️ news.ubc.ca/2026/01/firs...
Scientists develop first gene-editing treatment for skin conditions
UBC researchers have created a topical CRISPR-based therapy that could offer a lasting cure for a range of skin disorders.
news.ubc.ca
January 27, 2026 at 7:29 PM
Super proud of this work from my lab that has great translational potential and can fundamentally change how we treat skin diseases.
Reposted by Sarah Hedtrich
Please 🔁! #MASSIV will be held in Vancouver from January 19-22, 2026. 4-day meeting on #synbio x #tissueengineering.
Some trainee-focused events. >50 talks (10 from abstracts), posters, panel & publishing insights sessions.
www.massivconference.com
Abstract deadline: Nov 14
Some trainee-focused events. >50 talks (10 from abstracts), posters, panel & publishing insights sessions.
www.massivconference.com
Abstract deadline: Nov 14
October 25, 2025 at 4:21 PM
Please 🔁! #MASSIV will be held in Vancouver from January 19-22, 2026. 4-day meeting on #synbio x #tissueengineering.
Some trainee-focused events. >50 talks (10 from abstracts), posters, panel & publishing insights sessions.
www.massivconference.com
Abstract deadline: Nov 14
Some trainee-focused events. >50 talks (10 from abstracts), posters, panel & publishing insights sessions.
www.massivconference.com
Abstract deadline: Nov 14
I’m very excited to speak at Nature Conferences this October. Join me and fellow researchers from across various disciplines to discuss insights on in vitro disease models and tissue engineering. Abstract submissions welcome. 👉 go.nature.com/43xmvlH
Engineered Models of Human Disease
Join a pioneering conference focused on the development of human-relevant in vitro disease models. The program brings together leading biologists, bioengineers, clinical researchers, computational res...
go.nature.com
July 2, 2025 at 6:36 PM
I’m very excited to speak at Nature Conferences this October. Join me and fellow researchers from across various disciplines to discuss insights on in vitro disease models and tissue engineering. Abstract submissions welcome. 👉 go.nature.com/43xmvlH
Great conference on human-based models coming up! Register now!
Engineered Models of Human Disease is set to be an incredible conference in Belgrade this Fall!
Speakers include many heavy hitters in the field, such as:
@hedtrichlab.bsky.social and
@hansclevers.bsky.social
Early bird registration still open! 🧪
natureconferences.streamgo.live/models-human...
Speakers include many heavy hitters in the field, such as:
@hedtrichlab.bsky.social and
@hansclevers.bsky.social
Early bird registration still open! 🧪
natureconferences.streamgo.live/models-human...
Engineered Models of Human Disease
Join a pioneering conference focused on the development of human-relevant in vitro disease models. The program brings together leading biologists, bioengineers, clinical researchers, computational res...
natureconferences.streamgo.live
May 15, 2025 at 9:55 PM
Great conference on human-based models coming up! Register now!
Reposted by Sarah Hedtrich
UBC is hosting US Applicant Week from April 14-18, which allows US students to apply during an extended application period for graduate studies. Sixty graduate programs will be reopening applications for US applicants for September 2025 and January 2026 start dates - www.grad.ubc.ca/us-applicant...
April 7, 2025 at 10:47 PM
UBC is hosting US Applicant Week from April 14-18, which allows US students to apply during an extended application period for graduate studies. Sixty graduate programs will be reopening applications for US applicants for September 2025 and January 2026 start dates - www.grad.ubc.ca/us-applicant...
Reposted by Sarah Hedtrich
Come join us at beautiful UBC! The King Lab is recruiting a Post-doc Fellow to develop mathematical theory on infectious disease evolution and emergence, together with Ben Ashby (SFU) #zoonoses #biodiversity www.zoology.ubc.ca/kinglab/join...
Join Us! | King Lab
Are you interested in joining the King Lab? More information here!
www.zoology.ubc.ca
March 31, 2025 at 1:22 AM
Come join us at beautiful UBC! The King Lab is recruiting a Post-doc Fellow to develop mathematical theory on infectious disease evolution and emergence, together with Ben Ashby (SFU) #zoonoses #biodiversity www.zoology.ubc.ca/kinglab/join...
Reposted by Sarah Hedtrich
We are recruiting! The McGill University Department of Pharmacology and Therapeutics in the Faculty of Medicine and Health Sciences invites applications for a full-time tenure track Assistant or Associate Professor position in the area of toxicology.
mcgill.wd3.myworkdayjobs.com/en-US/McGill...
mcgill.wd3.myworkdayjobs.com/en-US/McGill...
Assistant/Associate Professor (Tenure Track), Department of Pharmacology and Therapeutics, Toxicology (L000054)
Please refer to the How to Apply for a Job (for External Candidates) job aid for instructions on how to apply. If you are an active McGill employee (ie: currently in an active contract or position at ...
mcgill.wd3.myworkdayjobs.com
March 24, 2025 at 4:28 PM
We are recruiting! The McGill University Department of Pharmacology and Therapeutics in the Faculty of Medicine and Health Sciences invites applications for a full-time tenure track Assistant or Associate Professor position in the area of toxicology.
mcgill.wd3.myworkdayjobs.com/en-US/McGill...
mcgill.wd3.myworkdayjobs.com/en-US/McGill...