Dr DJ Pet Daddy 🌻🌹☄️
@haterdvm.bsky.social
shelter veterinarian, kentuckian, breakfast lover, cop hater. here to learn about anti-fascist organizing, surgery/anesthesia, and shit posting. he/him
Reposted by Dr DJ Pet Daddy 🌻🌹☄️
The TikTok ban is sort of a golem constructed of all of Congress' fears, anxieties, and unfinished work related to tech. It's a monstrous amalgamation of generalized anti-China sentiment / xenophobia / sinophobia, fears about Big Tech, content moderation, Palestine, "the kids" all rolled into one
January 19, 2025 at 2:35 PM
The TikTok ban is sort of a golem constructed of all of Congress' fears, anxieties, and unfinished work related to tech. It's a monstrous amalgamation of generalized anti-China sentiment / xenophobia / sinophobia, fears about Big Tech, content moderation, Palestine, "the kids" all rolled into one
"How long has she worked there?"
Ah sorry, we only grant leave requests for shooting victims who have been part of the Amazon Family for 2+ years!
Ah sorry, we only grant leave requests for shooting victims who have been part of the Amazon Family for 2+ years!
January 3, 2025 at 5:33 PM
If you enjoy learning about #VetMed through a chemical, historical, and political lens, give me a follow!
Curious about how other tools in vet med work? Or want more science deep dives? Stay tuned for future threads! Suggestions always welcome-let's learn together!
#vetmed #science
Curious about how other tools in vet med work? Or want more science deep dives? Stay tuned for future threads! Suggestions always welcome-let's learn together!
#vetmed #science
January 3, 2025 at 4:36 PM
In summary, buprenorphine offers safe, long-lasting pain relief with fewer side effects than traditional opioids.
It's time to give this underappreciated drug its due!
It's time to give this underappreciated drug its due!
January 3, 2025 at 4:36 PM
In summary, buprenorphine offers safe, long-lasting pain relief with fewer side effects than traditional opioids.
It's time to give this underappreciated drug its due!
It's time to give this underappreciated drug its due!
Buprenorphine isn't just for routine pain management. It can also be used for:
😷 🥼Spidural anesthesia (great for surgeries!)
💉🦷Dental nerve blocks (hello, tooth extractions!)
A versatile tool in our pain relief arsenal. #veterinarymedicine
😷 🥼Spidural anesthesia (great for surgeries!)
💉🦷Dental nerve blocks (hello, tooth extractions!)
A versatile tool in our pain relief arsenal. #veterinarymedicine
January 3, 2025 at 4:33 PM
Buprenorphine isn't just for routine pain management. It can also be used for:
😷 🥼Spidural anesthesia (great for surgeries!)
💉🦷Dental nerve blocks (hello, tooth extractions!)
A versatile tool in our pain relief arsenal. #veterinarymedicine
😷 🥼Spidural anesthesia (great for surgeries!)
💉🦷Dental nerve blocks (hello, tooth extractions!)
A versatile tool in our pain relief arsenal. #veterinarymedicine
Buprenorphine also causes dysphoria less often than pure mu opioids. If a French bulldog wakes up from anesthesia anxious and thrashing in the cage, that can lead to airway instruction and post anesthetic death! Staying calm post-op is key, and buprenorphine does that better than almost any other.
January 3, 2025 at 4:30 PM
Buprenorphine also causes dysphoria less often than pure mu opioids. If a French bulldog wakes up from anesthesia anxious and thrashing in the cage, that can lead to airway instruction and post anesthetic death! Staying calm post-op is key, and buprenorphine does that better than almost any other.
Why is buprenorphine great for dogs?
✔️ Long-acting (6-12 hrs vs. ~2 hrs for hydromorphone)
✔️Minimal nausea (perfect for brachycephalic breeds like Pugs and Bulldogs to avoid vomiting
✔️ "Ceiling effect" = higher doses result in longer duration, not stronger effect, lowering overdose risk.
✔️ Long-acting (6-12 hrs vs. ~2 hrs for hydromorphone)
✔️Minimal nausea (perfect for brachycephalic breeds like Pugs and Bulldogs to avoid vomiting
✔️ "Ceiling effect" = higher doses result in longer duration, not stronger effect, lowering overdose risk.
January 3, 2025 at 4:28 PM
Why is buprenorphine great for dogs?
✔️ Long-acting (6-12 hrs vs. ~2 hrs for hydromorphone)
✔️Minimal nausea (perfect for brachycephalic breeds like Pugs and Bulldogs to avoid vomiting
✔️ "Ceiling effect" = higher doses result in longer duration, not stronger effect, lowering overdose risk.
✔️ Long-acting (6-12 hrs vs. ~2 hrs for hydromorphone)
✔️Minimal nausea (perfect for brachycephalic breeds like Pugs and Bulldogs to avoid vomiting
✔️ "Ceiling effect" = higher doses result in longer duration, not stronger effect, lowering overdose risk.
Used in human medicine for pain and opioid addiction (Suboxone®, Buprenex®), it's a game-changer in vet med for its long duration and fewer side effects.
#vetmed #surgery #anesthesia
#vetmed #surgery #anesthesia
January 3, 2025 at 4:23 PM
Used in human medicine for pain and opioid addiction (Suboxone®, Buprenex®), it's a game-changer in vet med for its long duration and fewer side effects.
#vetmed #surgery #anesthesia
#vetmed #surgery #anesthesia
In the 1960s, buprenorphine was introduced. It binds to mu receptors, like those above, but those are "pure" mu opioids. Buprenorphine is a "partial" opioid, which gives it unique benefits and properties
January 3, 2025 at 4:21 PM
In the 1960s, buprenorphine was introduced. It binds to mu receptors, like those above, but those are "pure" mu opioids. Buprenorphine is a "partial" opioid, which gives it unique benefits and properties
There are many, many other receptors and the role of opioids and endogenous opioids (endorphins) is very complex. We'll never know everything, which is why I love medicine. You don't have to get bogged down in the theory, you can give a drug (carefully calculated of course) and see what happens!
January 3, 2025 at 4:17 PM
There are many, many other receptors and the role of opioids and endogenous opioids (endorphins) is very complex. We'll never know everything, which is why I love medicine. You don't have to get bogged down in the theory, you can give a drug (carefully calculated of course) and see what happens!
Mu (μ) - target of drugs like hydromorphone, fentanyl, methadone. Activity here = excellent pain relief, with side effects like nausea and dysphoria.
Kappa (k) - opioids that bind here (butorphanol) offer shorter lived, less potent pain relief, with more sedation and fewer side effects
Kappa (k) - opioids that bind here (butorphanol) offer shorter lived, less potent pain relief, with more sedation and fewer side effects
January 3, 2025 at 4:14 PM
Mu (μ) - target of drugs like hydromorphone, fentanyl, methadone. Activity here = excellent pain relief, with side effects like nausea and dysphoria.
Kappa (k) - opioids that bind here (butorphanol) offer shorter lived, less potent pain relief, with more sedation and fewer side effects
Kappa (k) - opioids that bind here (butorphanol) offer shorter lived, less potent pain relief, with more sedation and fewer side effects
A quick word on receptors:
Opioids work mostly by their activity on opioid receptors in the brain and spinal cord. But did you know there are multiple types of opioid receptors? #veterinary #anesthesia
Opioids work mostly by their activity on opioid receptors in the brain and spinal cord. But did you know there are multiple types of opioid receptors? #veterinary #anesthesia
January 3, 2025 at 4:09 PM
A quick word on receptors:
Opioids work mostly by their activity on opioid receptors in the brain and spinal cord. But did you know there are multiple types of opioid receptors? #veterinary #anesthesia
Opioids work mostly by their activity on opioid receptors in the brain and spinal cord. But did you know there are multiple types of opioid receptors? #veterinary #anesthesia
In the 1930s, morphine was used for colic in horses, coughing dogs, and of course painful surgical procedures.
Other widely used opioids in veterinary medicine, like hydromorphone and fentanyl, wouldn't come until much later.
Other widely used opioids in veterinary medicine, like hydromorphone and fentanyl, wouldn't come until much later.
January 3, 2025 at 4:07 PM
In the 1930s, morphine was used for colic in horses, coughing dogs, and of course painful surgical procedures.
Other widely used opioids in veterinary medicine, like hydromorphone and fentanyl, wouldn't come until much later.
Other widely used opioids in veterinary medicine, like hydromorphone and fentanyl, wouldn't come until much later.
The first veterinary surgical textbook was published in 1912, and by the time the still-famous Merck Veterinary Manual was published in 1955, there was a high demand for anesthetic knowledge to match the advancing field of veterinary surgery. #vetmed
January 3, 2025 at 4:00 PM
The first veterinary surgical textbook was published in 1912, and by the time the still-famous Merck Veterinary Manual was published in 1955, there was a high demand for anesthetic knowledge to match the advancing field of veterinary surgery. #vetmed
Opioids have been used for pain relief since ancient Mesopotamia (around 3400 BCE!). In the 1800s, morphine was isolated from the poppy plant. By the 20th century, synthetic opioids like fentanyl revolutionized pain management. But when did opioids enter veterinary practice?
January 3, 2025 at 3:56 PM
Opioids have been used for pain relief since ancient Mesopotamia (around 3400 BCE!). In the 1800s, morphine was isolated from the poppy plant. By the 20th century, synthetic opioids like fentanyl revolutionized pain management. But when did opioids enter veterinary practice?
Surgical correction is the treatment of choice! Will circle back when he has that procedure in a couple weeks.
In the meantime: an antibiotic eye drop (NeoPolyBac every 8 hrs), an immune-modulating ointment (Optimmune every 12 hrs) to reduce chronic inflammation, and lube (for comfort!)
In the meantime: an antibiotic eye drop (NeoPolyBac every 8 hrs), an immune-modulating ointment (Optimmune every 12 hrs) to reduce chronic inflammation, and lube (for comfort!)
December 29, 2024 at 4:53 PM
Surgical correction is the treatment of choice! Will circle back when he has that procedure in a couple weeks.
In the meantime: an antibiotic eye drop (NeoPolyBac every 8 hrs), an immune-modulating ointment (Optimmune every 12 hrs) to reduce chronic inflammation, and lube (for comfort!)
In the meantime: an antibiotic eye drop (NeoPolyBac every 8 hrs), an immune-modulating ointment (Optimmune every 12 hrs) to reduce chronic inflammation, and lube (for comfort!)