Pawel Grzechnik
@grzechnikpawel.bsky.social
Group Leader and Lecturer, Division of Molecular and Cellular Function, FBMH, University of Manchester
Transcription, ncRNAs and rare genetic diseases | Loves all types of martial arts
www.grzechniklab.com
Transcription, ncRNAs and rare genetic diseases | Loves all types of martial arts
www.grzechniklab.com
Reposted by Pawel Grzechnik
Two positions (research assistant and PhD student), great science and the cake!
Check @buckleylab.bsky.social thread for more info:
👇
Check @buckleylab.bsky.social thread for more info:
👇
2 positions up for grabs in the Buckley lab - join us for some fun with optogenetics, zebrafish, neural tubes, biomechanics and cake
November 20, 2025 at 11:46 AM
Two positions (research assistant and PhD student), great science and the cake!
Check @buckleylab.bsky.social thread for more info:
👇
Check @buckleylab.bsky.social thread for more info:
👇
Reposted by Pawel Grzechnik
Structural biologists!
Our division has an opening for a Lecturer/Senior Lecturer—apply now!
www.jobs.manchester.ac.uk/Job/JobDetai...
Our division has an opening for a Lecturer/Senior Lecturer—apply now!
www.jobs.manchester.ac.uk/Job/JobDetai...
Lecturer / Senior Lecturer in Structural Biology:Oxford Road
The purpose of this post is to undertake high quality research and also excellent teaching. Hence, the ability to enhance teaching activities within our UG/PG programmes will also be expected.
www.jobs.manchester.ac.uk
November 15, 2025 at 3:44 PM
Structural biologists!
Our division has an opening for a Lecturer/Senior Lecturer—apply now!
www.jobs.manchester.ac.uk/Job/JobDetai...
Our division has an opening for a Lecturer/Senior Lecturer—apply now!
www.jobs.manchester.ac.uk/Job/JobDetai...
Reposted by Pawel Grzechnik
Reposted by Pawel Grzechnik
We are excited to announce that Professor Graham Pavitt, Chair in Molecular Biology, has been appointed as our new Head of Division!
Join us in welcoming Graham to his new role—we look forward to the exciting times ahead!
research.manchester.ac.uk/en/persons/g...
Join us in welcoming Graham to his new role—we look forward to the exciting times ahead!
research.manchester.ac.uk/en/persons/g...
Graham Pavitt
research.manchester.ac.uk
July 17, 2025 at 8:10 AM
We are excited to announce that Professor Graham Pavitt, Chair in Molecular Biology, has been appointed as our new Head of Division!
Join us in welcoming Graham to his new role—we look forward to the exciting times ahead!
research.manchester.ac.uk/en/persons/g...
Join us in welcoming Graham to his new role—we look forward to the exciting times ahead!
research.manchester.ac.uk/en/persons/g...
Reposted by Pawel Grzechnik
Early-career fellowships at the University of Manchester!
To celebrate 200 years of The University of Manchester, the Faculty of Biology Medicine and Health offers a 3-year Postdoctoral Fellowship to support exceptional early-career researchers:
www.bmh.manchester.ac.uk/research/sup...
To celebrate 200 years of The University of Manchester, the Faculty of Biology Medicine and Health offers a 3-year Postdoctoral Fellowship to support exceptional early-career researchers:
www.bmh.manchester.ac.uk/research/sup...
Bicentenary Early Career Research Fellowships | Biology, Medicine and Health | University of Manchester
Find out about and apply for a Bicentenary Early Career Research Fellowship.
www.bmh.manchester.ac.uk
March 4, 2025 at 9:21 PM
Early-career fellowships at the University of Manchester!
To celebrate 200 years of The University of Manchester, the Faculty of Biology Medicine and Health offers a 3-year Postdoctoral Fellowship to support exceptional early-career researchers:
www.bmh.manchester.ac.uk/research/sup...
To celebrate 200 years of The University of Manchester, the Faculty of Biology Medicine and Health offers a 3-year Postdoctoral Fellowship to support exceptional early-career researchers:
www.bmh.manchester.ac.uk/research/sup...
Reposted by Pawel Grzechnik
Exciting PhD opportunity available in my lab for the students from Black heritage background. Apply soon. 🤞🤞🤞
@mcr-breastcentre.bsky.social @mcf-uom.bsky.social
CRUK Black Leaders in Cancer Non-Clinical PhD Opportunity
📅 Deadline: 4 April
🔗 crukcentre.manchester.ac.uk/study/resear...
@mcr-breastcentre.bsky.social @mcf-uom.bsky.social
CRUK Black Leaders in Cancer Non-Clinical PhD Opportunity
📅 Deadline: 4 April
🔗 crukcentre.manchester.ac.uk/study/resear...
Research Opportunities - Cancer Research UK Manchester Centre
Explore the range of postgraduate cancer research opportunities available in Manchester.
crukcentre.manchester.ac.uk
March 4, 2025 at 8:18 PM
Exciting PhD opportunity available in my lab for the students from Black heritage background. Apply soon. 🤞🤞🤞
@mcr-breastcentre.bsky.social @mcf-uom.bsky.social
CRUK Black Leaders in Cancer Non-Clinical PhD Opportunity
📅 Deadline: 4 April
🔗 crukcentre.manchester.ac.uk/study/resear...
@mcr-breastcentre.bsky.social @mcf-uom.bsky.social
CRUK Black Leaders in Cancer Non-Clinical PhD Opportunity
📅 Deadline: 4 April
🔗 crukcentre.manchester.ac.uk/study/resear...
Reposted by Pawel Grzechnik
Our lab's very first manuscript is out in BioRxiv. Hope this would be interesting for breast cancer scientists: www.biorxiv.org/content/10.1... @mcf-uom.bsky.social @mcr-breastcentre.bsky.social @mcrcnews.bsky.social @official-uom.bsky.social @fbmh-uom.bsky.social
Subtype-specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Gene expression is tightly controlled by DNA elements called enhancers by associating with lineage-specific transcription factors. These enhancers transcribe non-coding RNAs (called enhancer RNAs or e...
www.biorxiv.org
March 4, 2025 at 8:20 PM
Our lab's very first manuscript is out in BioRxiv. Hope this would be interesting for breast cancer scientists: www.biorxiv.org/content/10.1... @mcf-uom.bsky.social @mcr-breastcentre.bsky.social @mcrcnews.bsky.social @official-uom.bsky.social @fbmh-uom.bsky.social
Reposted by Pawel Grzechnik
A fantastic postdoc opportunity available for talented PhD graduates to work in our CRUK funded PhD project.
jobs.manchester.ac.uk/internal/Job...
@mcr-breastcentre.bsky.social @mcrcnews.bsky.social @mcf-uom.bsky.social @mcrcellmatrix.bsky.social @official-uom.bsky.social @fbmh-uom.bsky.social
jobs.manchester.ac.uk/internal/Job...
@mcr-breastcentre.bsky.social @mcrcnews.bsky.social @mcf-uom.bsky.social @mcrcellmatrix.bsky.social @official-uom.bsky.social @fbmh-uom.bsky.social
jobs.manchester.ac.uk
March 4, 2025 at 8:14 PM
A fantastic postdoc opportunity available for talented PhD graduates to work in our CRUK funded PhD project.
jobs.manchester.ac.uk/internal/Job...
@mcr-breastcentre.bsky.social @mcrcnews.bsky.social @mcf-uom.bsky.social @mcrcellmatrix.bsky.social @official-uom.bsky.social @fbmh-uom.bsky.social
jobs.manchester.ac.uk/internal/Job...
@mcr-breastcentre.bsky.social @mcrcnews.bsky.social @mcf-uom.bsky.social @mcrcellmatrix.bsky.social @official-uom.bsky.social @fbmh-uom.bsky.social
Which side are you on?
February 28, 2025 at 10:57 PM
Which side are you on?
Reposted by Pawel Grzechnik
You can donate to support Ukraine's defence, humanitarian demining, medical aid, the rebuilding of Ukraine or education & science here: u24.gov.ua
I just donated. Slava Ukraini!
I just donated. Slava Ukraini!
UNITED24 - The initiative of the President of Ukraine
UNITED24 was launched by the President of Ukraine Volodymyr Zelenskyy as the main venue for collecting charitable donations in support of Ukraine. Funds will be transferred to the official accounts of...
u24.gov.ua
February 28, 2025 at 9:38 PM
You can donate to support Ukraine's defence, humanitarian demining, medical aid, the rebuilding of Ukraine or education & science here: u24.gov.ua
I just donated. Slava Ukraini!
I just donated. Slava Ukraini!
Reposted by Pawel Grzechnik
Another chance to join our group! Center for Gene Expression has 2 or more postdoc positions @ucph.bsky.social in wonderful Copenhagen. Want to join our team to work on transcriptional regulation? More information at: gregersenlab.com Deadline March 18. Apply here: jobportal.ku.dk/phd/?show=16...
Gegersen Lab
The aim of the lab is to understand regulation of transcription and co-transcriptional processing in human cells
gregersenlab.com
February 21, 2025 at 8:56 AM
Another chance to join our group! Center for Gene Expression has 2 or more postdoc positions @ucph.bsky.social in wonderful Copenhagen. Want to join our team to work on transcriptional regulation? More information at: gregersenlab.com Deadline March 18. Apply here: jobportal.ku.dk/phd/?show=16...
Reposted by Pawel Grzechnik
We are looking to recruit a highly motivated postdoc with cell or molecular biology expertise. Excellent #epigenetics, #chromatin training & networking opportunities @qmulepigenetics.bsky.social
DM me for inquiries
pl apply/share tinyurl.com/m6jnksk5
DM me for inquiries
pl apply/share tinyurl.com/m6jnksk5
a cartoon of homer simpson and bart simpson sitting on a couch with the words join us above them .
ALT: a cartoon of homer simpson and bart simpson sitting on a couch with the words join us above them .
media.tenor.com
February 13, 2025 at 1:23 PM
We are looking to recruit a highly motivated postdoc with cell or molecular biology expertise. Excellent #epigenetics, #chromatin training & networking opportunities @qmulepigenetics.bsky.social
DM me for inquiries
pl apply/share tinyurl.com/m6jnksk5
DM me for inquiries
pl apply/share tinyurl.com/m6jnksk5
Reposted by Pawel Grzechnik
We are recruiting! Center for Gene Expression has 2 or more open positions for PhDs @ucph.bsky.social. Come join our team to work on RNAPII and transcriptional regulation (gregersenlab.com). It's a wonderful city and amazing research environment. Deadline March 6. jobportal.ku.dk/phd/?show=16...
February 13, 2025 at 8:09 PM
We are recruiting! Center for Gene Expression has 2 or more open positions for PhDs @ucph.bsky.social. Come join our team to work on RNAPII and transcriptional regulation (gregersenlab.com). It's a wonderful city and amazing research environment. Deadline March 6. jobportal.ku.dk/phd/?show=16...
Reposted by Pawel Grzechnik
Pls. share: We're putting together a series on inequalities associated with academic mobility.
If you're a microbiologist and would like to share your experiences with visa difficulties, travel-related funding, mandated academic mobility requirements, etc, please write at [email protected].
#MicroSky
If you're a microbiologist and would like to share your experiences with visa difficulties, travel-related funding, mandated academic mobility requirements, etc, please write at [email protected].
#MicroSky
February 6, 2025 at 9:31 AM
Pls. share: We're putting together a series on inequalities associated with academic mobility.
If you're a microbiologist and would like to share your experiences with visa difficulties, travel-related funding, mandated academic mobility requirements, etc, please write at [email protected].
#MicroSky
If you're a microbiologist and would like to share your experiences with visa difficulties, travel-related funding, mandated academic mobility requirements, etc, please write at [email protected].
#MicroSky
Reposted by Pawel Grzechnik
Ever wondered how Pol II speed is controlled during productive elongation?
Our study reveals that the helicase RECQL5 triggers transcription braking, while the transcription-coupled DNA repair complex restores the elongation rate. #cryoEM #transcription
www.biorxiv.org/content/10.1...
Our study reveals that the helicase RECQL5 triggers transcription braking, while the transcription-coupled DNA repair complex restores the elongation rate. #cryoEM #transcription
www.biorxiv.org/content/10.1...
February 3, 2025 at 12:23 PM
Ever wondered how Pol II speed is controlled during productive elongation?
Our study reveals that the helicase RECQL5 triggers transcription braking, while the transcription-coupled DNA repair complex restores the elongation rate. #cryoEM #transcription
www.biorxiv.org/content/10.1...
Our study reveals that the helicase RECQL5 triggers transcription braking, while the transcription-coupled DNA repair complex restores the elongation rate. #cryoEM #transcription
www.biorxiv.org/content/10.1...
Reposted by Pawel Grzechnik
📢1/12 Happy to share our first bluetutorial & our latest preprint. In this work, we discovered RSRC2 as a novel RNA-binding protein (RBP) with a dual function in cell division whose activity can be (lnc)RNA-mediated. #lncRNA #RBP #Mitosis
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
The RNA-binding protein RSRC2 promotes mitotic fidelity by interacting with the lncRNA C1QTNF1-AS1
Mitotic fidelity depends on proper chromosome alignment at the spindle equator, a process known as chromosome congression, driven by well-established protein networks. Whereas RNA-binding proteins and...
www.biorxiv.org
January 23, 2025 at 5:26 PM
📢1/12 Happy to share our first bluetutorial & our latest preprint. In this work, we discovered RSRC2 as a novel RNA-binding protein (RBP) with a dual function in cell division whose activity can be (lnc)RNA-mediated. #lncRNA #RBP #Mitosis
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
We joined the Laboratory Efficiency Assessment Framework (LEAF), reduced laboratory waste and energy usage, and made the lab more sustainable overall.
And so we got the LEAF GOLD award!
And so we got the LEAF GOLD award!
January 24, 2025 at 8:25 AM
We joined the Laboratory Efficiency Assessment Framework (LEAF), reduced laboratory waste and energy usage, and made the lab more sustainable overall.
And so we got the LEAF GOLD award!
And so we got the LEAF GOLD award!
Reposted by Pawel Grzechnik
As you make have seen, there is a special issue of JMB on "Controlling Transcription Elongation and Termination: More Than a Means to An End" curated by my colleague here at Pitt Karen Arndt and by Steve Buratowski from Harvard Medical School 🧪🧵 1/ www.sciencedirect.com/science/arti...
Controlling Transcription Elongation and Termination: More Than a Means to An End
www.sciencedirect.com
November 27, 2024 at 3:00 PM
As you make have seen, there is a special issue of JMB on "Controlling Transcription Elongation and Termination: More Than a Means to An End" curated by my colleague here at Pitt Karen Arndt and by Steve Buratowski from Harvard Medical School 🧪🧵 1/ www.sciencedirect.com/science/arti...
Reposted by Pawel Grzechnik
Pawel Grzechnik and Hannah Mischo discuss polyadenylation site recognition and what happens afterwards and how it can go wrong: Fateful Decisions of Where to Cut the Line: Pathology Associated with Aberrant 3′ End Processing and Transcription Termination 14/ www.sciencedirect.com/science/arti...
Fateful Decisions of Where to Cut the Line: Pathology Associated with Aberrant 3′ End Processing and Transcription Termination
Aberrant gene expression lies at the heart of many pathologies. This review will point out how 3′ end processing, the final mRNA-maturation step in th…
www.sciencedirect.com
November 27, 2024 at 3:00 PM
Pawel Grzechnik and Hannah Mischo discuss polyadenylation site recognition and what happens afterwards and how it can go wrong: Fateful Decisions of Where to Cut the Line: Pathology Associated with Aberrant 3′ End Processing and Transcription Termination 14/ www.sciencedirect.com/science/arti...
some good reviews there!
As you make have seen, there is a special issue of JMB on "Controlling Transcription Elongation and Termination: More Than a Means to An End" curated by my colleague here at Pitt Karen Arndt and by Steve Buratowski from Harvard Medical School 🧪🧵 1/ www.sciencedirect.com/science/arti...
Controlling Transcription Elongation and Termination: More Than a Means to An End
www.sciencedirect.com
November 28, 2024 at 9:33 AM
some good reviews there!
Reposted by Pawel Grzechnik
Look who's here
@pnas.org ✔️
@science.org ✔️
@naturecellbiology.bsky.social ✔️
@natrevgenet.bsky.social ✔️
@naturebiotech.bsky.social ✔️
@naturemicrobiol.bsky.social ✔️
@naturechemistry.bsky.social ✔️
@genesdev.bsky.social ✔️
@cellchembiol.bsky.social ✔️
@genomeresearch.bsky.social ✔️
@jcellbiol.bsky.social ✔️
@pnas.org ✔️
@science.org ✔️
@naturecellbiology.bsky.social ✔️
@natrevgenet.bsky.social ✔️
@naturebiotech.bsky.social ✔️
@naturemicrobiol.bsky.social ✔️
@naturechemistry.bsky.social ✔️
@genesdev.bsky.social ✔️
@cellchembiol.bsky.social ✔️
@genomeresearch.bsky.social ✔️
@jcellbiol.bsky.social ✔️
November 25, 2024 at 1:47 PM
Look who's here
@pnas.org ✔️
@science.org ✔️
@naturecellbiology.bsky.social ✔️
@natrevgenet.bsky.social ✔️
@naturebiotech.bsky.social ✔️
@naturemicrobiol.bsky.social ✔️
@naturechemistry.bsky.social ✔️
@genesdev.bsky.social ✔️
@cellchembiol.bsky.social ✔️
@genomeresearch.bsky.social ✔️
@jcellbiol.bsky.social ✔️
@pnas.org ✔️
@science.org ✔️
@naturecellbiology.bsky.social ✔️
@natrevgenet.bsky.social ✔️
@naturebiotech.bsky.social ✔️
@naturemicrobiol.bsky.social ✔️
@naturechemistry.bsky.social ✔️
@genesdev.bsky.social ✔️
@cellchembiol.bsky.social ✔️
@genomeresearch.bsky.social ✔️
@jcellbiol.bsky.social ✔️
Reposted by Pawel Grzechnik
📢 Interested in chromosomes and microbes thriving at the edge of life?PhD project in York-UK on chromosome segregation in #Archaea.
Supervised by me, @Steve Quinn & @georgerheath.bsky.social
www.findaphd.com/phds/project...
Open to Applicants Worldwide!
📅 January 6, 2025
#microsky #archaeasky
Supervised by me, @Steve Quinn & @georgerheath.bsky.social
www.findaphd.com/phds/project...
Open to Applicants Worldwide!
📅 January 6, 2025
#microsky #archaeasky
November 23, 2024 at 1:10 PM
📢 Interested in chromosomes and microbes thriving at the edge of life?PhD project in York-UK on chromosome segregation in #Archaea.
Supervised by me, @Steve Quinn & @georgerheath.bsky.social
www.findaphd.com/phds/project...
Open to Applicants Worldwide!
📅 January 6, 2025
#microsky #archaeasky
Supervised by me, @Steve Quinn & @georgerheath.bsky.social
www.findaphd.com/phds/project...
Open to Applicants Worldwide!
📅 January 6, 2025
#microsky #archaeasky
Let’s encourage our host institutes and organizations to move to Bluesky!
Follow those already here (UK starter pack), and let me know about others who have joined!
go.bsky.app/JMrhz8Q
Follow those already here (UK starter pack), and let me know about others who have joined!
go.bsky.app/JMrhz8Q
November 22, 2024 at 8:51 AM
Let’s encourage our host institutes and organizations to move to Bluesky!
Follow those already here (UK starter pack), and let me know about others who have joined!
go.bsky.app/JMrhz8Q
Follow those already here (UK starter pack), and let me know about others who have joined!
go.bsky.app/JMrhz8Q
Reposted by Pawel Grzechnik
Hello, Bluesky community!
We are the Division of Molecular and Cellular Function (MCF) in the Faculty of Biology, Medicine and Health at the University of Manchester.
Follow us for research updates and job opportunities!
We are the Division of Molecular and Cellular Function (MCF) in the Faculty of Biology, Medicine and Health at the University of Manchester.
Follow us for research updates and job opportunities!
November 21, 2024 at 8:25 PM
Hello, Bluesky community!
We are the Division of Molecular and Cellular Function (MCF) in the Faculty of Biology, Medicine and Health at the University of Manchester.
Follow us for research updates and job opportunities!
We are the Division of Molecular and Cellular Function (MCF) in the Faculty of Biology, Medicine and Health at the University of Manchester.
Follow us for research updates and job opportunities!