John Greally
greally.bsky.social
John Greally
@greally.bsky.social
Using genomic information to improve medicine
(The full quotation is "That's mad, Ted")

www.theguardian.com/tv-and-radio...
'That's mad, Ted': stamps launched for Father Ted's 25th anniversary
Stamps feature phrases from award-winning comedy set on fictional Craggy Island
www.theguardian.com
November 25, 2025 at 12:38 PM
I hope you enjoy it, thanks Jacob.
November 19, 2025 at 12:42 AM
"the possible stigmatization of individuals with these real conditions today" -- exactly why this study is repugnant.

I have patients with this condition, they really do not need to be dealing with this garbage science.
November 17, 2025 at 4:37 PM
A handy translation guide for non-academic speakers.
November 13, 2025 at 2:19 PM
Someone should write a book. Oh, wait...
November 12, 2025 at 3:54 PM
Yes, the bar is getting higher. But we have to get to that level to gain genuine biological insights.

Right now most DNA methylation studies on cohorts are cargo cult science.
November 12, 2025 at 3:21 PM
Furthermore, if rare variants have such major and cell type-specific effects, it's not enough to know about common variants in the individuals studied.
November 12, 2025 at 3:21 PM
It's worth stressing the point that those studying #epigenetics really need to be expert in genetics.

These variants are probably also reflected by small DNA methylation differences between individuals.

You can't interpret DNA methylation without knowing about genotype.
November 12, 2025 at 3:17 PM
Thanks Nico! I hope you like it!
November 11, 2025 at 7:43 PM
Outstanding book, loved it
November 11, 2025 at 3:13 AM
Squllionaires being sold a pig in a poke is just funny. But a child harmed by trash science sold by the unscrupulous is criminal.
November 9, 2025 at 1:06 PM
I suggest to colleagues that we hold off for the moment from the (valid) criticisms of this individual. A family is in mourning. There will be plenty of time for his history to be written.
November 8, 2025 at 2:28 AM