Steve Wise
@granularprefrontal.bsky.social
Retired neuroscientist, author, pickleball player
Reposted by Steve Wise
What's the role of #FrontopolarCortex (FPC) in evaluating alternative goals? @markboxf.bsky.social &co show that FPC activity tracks the value of #counterfactual rules via gamma & beta bursts; targeted FPC stimulation alters both neural signals & #DecisionMaking @plosbiology.org 🧪 plos.io/4ppd5lL
November 19, 2025 at 5:31 PM
What's the role of #FrontopolarCortex (FPC) in evaluating alternative goals? @markboxf.bsky.social &co show that FPC activity tracks the value of #counterfactual rules via gamma & beta bursts; targeted FPC stimulation alters both neural signals & #DecisionMaking @plosbiology.org 🧪 plos.io/4ppd5lL
Reposted by Steve Wise
"An emotional research team became tearful as they described how data shows the disease was slowed by 75% in patients...Prof Tabrizi says this gene therapy 'is the beginning' and will open the gates for therapies that can reach more people."🧪⚕️
Huntington's disease successfully treated for first time
One of the most devastating diseases finally has a treatment that can slow its progression and transform lives, tearful doctors tell BBC.
www.bbc.com
September 24, 2025 at 6:21 PM
"An emotional research team became tearful as they described how data shows the disease was slowed by 75% in patients...Prof Tabrizi says this gene therapy 'is the beginning' and will open the gates for therapies that can reach more people."🧪⚕️
Reposted by Steve Wise
Since start of 2025, as compared to the same period in 2024, Johns Hopkins has received 40% fewer federal awards, a decline of ~50% in research funding, a reduction of $500 million.
University wide, international graduate student enrollment is down by 8% since last year.
University wide, international graduate student enrollment is down by 8% since last year.
September 23, 2025 at 11:44 AM
Since start of 2025, as compared to the same period in 2024, Johns Hopkins has received 40% fewer federal awards, a decline of ~50% in research funding, a reduction of $500 million.
University wide, international graduate student enrollment is down by 8% since last year.
University wide, international graduate student enrollment is down by 8% since last year.
Reposted by Steve Wise
"For me, the answer now lies in refusal, the withdrawal of participation from systems that require dishonesty as the price of belonging."
Today I am resigning from the National Science Board and the Library of Congress Scholars Council.
I wrote about my decision in TIME.
time.com/7285045/resi...
Today I am resigning from the National Science Board and the Library of Congress Scholars Council.
I wrote about my decision in TIME.
time.com/7285045/resi...
Why I’m Resigning from the NSF and Library of Congress
I cannot participate in systems that require dishonesty as the price of belonging.
time.com
May 13, 2025 at 11:19 AM
"For me, the answer now lies in refusal, the withdrawal of participation from systems that require dishonesty as the price of belonging."
Today I am resigning from the National Science Board and the Library of Congress Scholars Council.
I wrote about my decision in TIME.
time.com/7285045/resi...
Today I am resigning from the National Science Board and the Library of Congress Scholars Council.
I wrote about my decision in TIME.
time.com/7285045/resi...
Reposted by Steve Wise
Neuroscientist Sarah Heilbronner is a proud product of Martin County schools in Florida 🌴. However, federal budget cuts threaten important work she's doing in brain research. 🧪🏠
@srheilbronner.bsky.social
www.tcpalm.com/story/opinio...
@srheilbronner.bsky.social
www.tcpalm.com/story/opinio...
Federal budget cuts threaten the work of neuroscientist with Martin County roots | Opinion
Sarah Heilbronner is a proud product of Martin County schools. However, federal budget cuts threaten important work she's doing in brain research.
www.tcpalm.com
March 2, 2025 at 3:11 PM
Neuroscientist Sarah Heilbronner is a proud product of Martin County schools in Florida 🌴. However, federal budget cuts threaten important work she's doing in brain research. 🧪🏠
@srheilbronner.bsky.social
www.tcpalm.com/story/opinio...
@srheilbronner.bsky.social
www.tcpalm.com/story/opinio...
Reposted by Steve Wise
“The devastation of losing something like [the Paleontological Research Institution] is monumental … It can never be replaced.” scim.ag/4ibbAUB
Financial peril could doom a famed New York paleontological institute
“Exceptional” fossil collections housed by the Paleontological Research Institute risk being orphaned
scim.ag
February 20, 2025 at 9:25 PM
“The devastation of losing something like [the Paleontological Research Institution] is monumental … It can never be replaced.” scim.ag/4ibbAUB
Reposted by Steve Wise
I wrote a column in my hometown newspaper about the importance of keeping SCIENCE FUNDING in our community 🧪
More soon about the power of writing back HOME 🏠
www.chicagotribune.com/2025/02/15/g...
More soon about the power of writing back HOME 🏠
www.chicagotribune.com/2025/02/15/g...
Guest column: Why science funding matters to Indiana
Last week the government cut “indirect costs” to universities and medical centers, which cover shared resources like buildings, utility bills, computer networks, and support staff. Indiana will los…
www.chicagotribune.com
February 18, 2025 at 12:33 PM
I wrote a column in my hometown newspaper about the importance of keeping SCIENCE FUNDING in our community 🧪
More soon about the power of writing back HOME 🏠
www.chicagotribune.com/2025/02/15/g...
More soon about the power of writing back HOME 🏠
www.chicagotribune.com/2025/02/15/g...
Reposted by Steve Wise
Kudos to Matt Ainsworth and Juan Galeazzi who are joint first authors on our preprint (and fond remembrance to our dear departed colleague Mark Stokes, also co-author).
First post: Q. What do you think happens if one high-freq. electrically microstimulates frontal pole (just 1 trial) while NHPs perform WCST task? They get better that's what (until rule-change then get worse)! Find out why with some mechanistic insight from LFPs here:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Frontopolar cortex stimulation induces prolonged disruption to counterfactual processing: insights from altered local field potentials
Frontopolar cortex (FPC) is a large, anterior sub-region of prefrontal cortex found in both humans and non-human primates (NHPs) and is thought to support monitoring the value of switching between alt...
www.biorxiv.org
December 10, 2024 at 12:46 PM
Kudos to Matt Ainsworth and Juan Galeazzi who are joint first authors on our preprint (and fond remembrance to our dear departed colleague Mark Stokes, also co-author).
Reposted by Steve Wise
Column by Thomas Boswell | Don’t despair over Juan Soto’s megadeal: The Mets and their big-spending owner will get what they deserve.
Column | Steve Cohen has stupid money, but this Juan Soto deal might be foolish
Don’t despair over Juan Soto’s megadeal: The Mets and their big-spending owner will get what they deserve.
wapo.st
December 10, 2024 at 7:10 PM
Column by Thomas Boswell | Don’t despair over Juan Soto’s megadeal: The Mets and their big-spending owner will get what they deserve.
Reposted by Steve Wise
I feel so honored by the publication of this special issue of Neuropsychologia. Thanks so much to my friends and colleagues who put this together. And thanks to all the contributors. There are so many wonderful articles. I can't tell you how delighted I am. 🧪🧠 www.sciencedirect.com/science/arti...
November 25, 2024 at 6:56 PM
I feel so honored by the publication of this special issue of Neuropsychologia. Thanks so much to my friends and colleagues who put this together. And thanks to all the contributors. There are so many wonderful articles. I can't tell you how delighted I am. 🧪🧠 www.sciencedirect.com/science/arti...
Reposted by Steve Wise
Neuroscientists are flocking to Bluesky, but X still has ten times more users. My story on the migration, featuring @nicolecrust.bsky.social @russpoldrack.bsky.social @charan-neuro.bsky.social @therealdrdukes.bsky.social @wiringthebrain.bsky.social + more! www.thetransmitter.org/community/hu...
‘Huge influx’ of neuroscientists migrates to Bluesky
Daily neuroscience-related posts on the social-media platform this week have increased more than 400 percent, on average, compared with October.
www.thetransmitter.org
November 21, 2024 at 5:14 PM
Neuroscientists are flocking to Bluesky, but X still has ten times more users. My story on the migration, featuring @nicolecrust.bsky.social @russpoldrack.bsky.social @charan-neuro.bsky.social @therealdrdukes.bsky.social @wiringthebrain.bsky.social + more! www.thetransmitter.org/community/hu...
Reposted by Steve Wise
hello neuroscientists! I am working on a story for @thetransmitter.bsky.social about the X to Bluesky migration and I would love to hear why you switched platforms (and what you make of bluesky so far). DM me or email me [email protected] if you'd like to comment for the piece. Thank you!
November 18, 2024 at 4:50 PM
hello neuroscientists! I am working on a story for @thetransmitter.bsky.social about the X to Bluesky migration and I would love to hear why you switched platforms (and what you make of bluesky so far). DM me or email me [email protected] if you'd like to comment for the piece. Thank you!
Reposted by Steve Wise
Thrilled that our paper on the role of the rat prelimbic cortex (PLC) in decision making is finally out! Three main findings are described in this thread
Co-authors: Jensen Palmer, Samantha White, and Kevin Chavez Lopez
doi.org/10.1523/JNEU...
Co-authors: Jensen Palmer, Samantha White, and Kevin Chavez Lopez
doi.org/10.1523/JNEU...
November 18, 2024 at 7:12 PM
Thrilled that our paper on the role of the rat prelimbic cortex (PLC) in decision making is finally out! Three main findings are described in this thread
Co-authors: Jensen Palmer, Samantha White, and Kevin Chavez Lopez
doi.org/10.1523/JNEU...
Co-authors: Jensen Palmer, Samantha White, and Kevin Chavez Lopez
doi.org/10.1523/JNEU...
Reposted by Steve Wise
26 years after Larry Swanson emphasized “the amygdala is neither a structural or functional unit” we used sn-RNAseq to answer the question:
“What is the [primate] amygdala?”
Check out the preprint 👇
www.biorxiv.org/content/10.1...
“What is the [primate] amygdala?”
Check out the preprint 👇
www.biorxiv.org/content/10.1...
October 19, 2024 at 5:58 PM
26 years after Larry Swanson emphasized “the amygdala is neither a structural or functional unit” we used sn-RNAseq to answer the question:
“What is the [primate] amygdala?”
Check out the preprint 👇
www.biorxiv.org/content/10.1...
“What is the [primate] amygdala?”
Check out the preprint 👇
www.biorxiv.org/content/10.1...
Reposted by Steve Wise
#neuroskyence This book is available in ebook format at a discounted price in November.
www.amazon.co.uk/Understandin...
www.amazon.co.uk/Understandin...
Understanding the Prefrontal Cortex: Selective advantage, connectivity, and neural operations (Oxford Psychology Series Book 53) eBook : Passingham, Richard: Amazon.co.uk: Books
Understanding the Prefrontal Cortex: Selective advantage, connectivity, and neural operations (Oxford Psychology Series Book 53) eBook : Passingham, Richard: Amazon.co.uk: Books
www.amazon.co.uk
September 20, 2024 at 7:02 PM
#neuroskyence This book is available in ebook format at a discounted price in November.
www.amazon.co.uk/Understandin...
www.amazon.co.uk/Understandin...
Oxford University Press has made Chapter 1 of my book, Cortical Evolution in Primates, available free of charge: fdslive.oup.com/www.oup.com/...
fdslive.oup.com
August 23, 2024 at 6:57 PM
Oxford University Press has made Chapter 1 of my book, Cortical Evolution in Primates, available free of charge: fdslive.oup.com/www.oup.com/...
Reposted by Steve Wise
Elon Musk’s first human experiment with the computerized brain device Neuralink developed significant flaws. But Noland Arbaugh, who is paralyzed and the first patient to take part in the human clinical trial, said he has few regrets.
Despite Setback, Neuralink’s First Brain-Implant Patient Stays Upbeat
Elon Musk’s first human experiment with a computerized brain device developed significant flaws, but the subject, who is paralyzed, has few regrets.
www.nytimes.com
May 22, 2024 at 7:09 PM
Elon Musk’s first human experiment with the computerized brain device Neuralink developed significant flaws. But Noland Arbaugh, who is paralyzed and the first patient to take part in the human clinical trial, said he has few regrets.
Reposted by Steve Wise
Widespread adoption of open-source tools calls for more support and training.
By @alexxai.bsky.social and @marklaubach.bsky.social
www.thetransmitter.org/open-neurosc...
By @alexxai.bsky.social and @marklaubach.bsky.social
www.thetransmitter.org/open-neurosc...
Unleashing the power of DIY innovation in behavioral neuroscience
Widespread adoption of open-source tools calls for more support and training.
www.thetransmitter.org
April 2, 2024 at 1:20 PM
Widespread adoption of open-source tools calls for more support and training.
By @alexxai.bsky.social and @marklaubach.bsky.social
www.thetransmitter.org/open-neurosc...
By @alexxai.bsky.social and @marklaubach.bsky.social
www.thetransmitter.org/open-neurosc...
Reposted by Steve Wise
i plan to move to Korea later this year, & will soon hire at all levels (students, postdocs, staff scientists, junior PIs) -
docs.google.com/document/d/1...
my lab in Japan will run till at least 2025. my job has been nothing but the dream job. but hopefully the above explains it.
#neuroscience
docs.google.com/document/d/1...
my lab in Japan will run till at least 2025. my job has been nothing but the dream job. but hopefully the above explains it.
#neuroscience
March 28, 2024 at 1:31 AM
i plan to move to Korea later this year, & will soon hire at all levels (students, postdocs, staff scientists, junior PIs) -
docs.google.com/document/d/1...
my lab in Japan will run till at least 2025. my job has been nothing but the dream job. but hopefully the above explains it.
#neuroscience
docs.google.com/document/d/1...
my lab in Japan will run till at least 2025. my job has been nothing but the dream job. but hopefully the above explains it.
#neuroscience
Reposted by Steve Wise
Sounds like fun, good luck with the move!
March 28, 2024 at 11:20 AM
Sounds like fun, good luck with the move!