existwell
@existwell.bsky.social
Science of psychedelics & other altered states of consciousness
Center for Psychedelic and Consciousness Research
@jhpsychedelics.bsky.social
Johns Hopkins University School of Medicine
Oxford Uehiro Institute
Yaden Lab
www.YadenLab.com
Center for Psychedelic and Consciousness Research
@jhpsychedelics.bsky.social
Johns Hopkins University School of Medicine
Oxford Uehiro Institute
Yaden Lab
www.YadenLab.com
Reposted by existwell
Here's an article on the course and our aims: www.hopkinsmedicine.org/news/article...
Johns Hopkins Researchers Create Course on Psychedelics
www.hopkinsmedicine.org
November 21, 2025 at 5:25 PM
Here's an article on the course and our aims: www.hopkinsmedicine.org/news/article...
Announcing a new Coursera on Psychedelic Science and Medicine!
From @jhpsychedelics.bsky.social, it provides info on psychedelic science, history, risks, benefits, trials, neuro, & more.
Taught by Drs. @fredbarrettphd.bsky.social, Garcia-Romeu, Nayak, Sayali, Tiwari, Yaden, & special guests-
From @jhpsychedelics.bsky.social, it provides info on psychedelic science, history, risks, benefits, trials, neuro, & more.
Taught by Drs. @fredbarrettphd.bsky.social, Garcia-Romeu, Nayak, Sayali, Tiwari, Yaden, & special guests-
November 21, 2025 at 5:24 PM
Announcing a new Coursera on Psychedelic Science and Medicine!
From @jhpsychedelics.bsky.social, it provides info on psychedelic science, history, risks, benefits, trials, neuro, & more.
Taught by Drs. @fredbarrettphd.bsky.social, Garcia-Romeu, Nayak, Sayali, Tiwari, Yaden, & special guests-
From @jhpsychedelics.bsky.social, it provides info on psychedelic science, history, risks, benefits, trials, neuro, & more.
Taught by Drs. @fredbarrettphd.bsky.social, Garcia-Romeu, Nayak, Sayali, Tiwari, Yaden, & special guests-
Reposted by existwell
CPCR Faculty
@existwell.bsky.social
will give a talk on his book, which is now out on paperback, in Baltimore near Johns Hopkins campus. Open to the public! Wednesday 11/19 at 6pm 11 E. 33rd St
@existwell.bsky.social
will give a talk on his book, which is now out on paperback, in Baltimore near Johns Hopkins campus. Open to the public! Wednesday 11/19 at 6pm 11 E. 33rd St
November 18, 2025 at 5:09 PM
CPCR Faculty
@existwell.bsky.social
will give a talk on his book, which is now out on paperback, in Baltimore near Johns Hopkins campus. Open to the public! Wednesday 11/19 at 6pm 11 E. 33rd St
@existwell.bsky.social
will give a talk on his book, which is now out on paperback, in Baltimore near Johns Hopkins campus. Open to the public! Wednesday 11/19 at 6pm 11 E. 33rd St
Reposted by existwell
#philsci #cogsky #CognitiveNeuroscience
@phaueis.bsky.social and I have had our paper, “Metabolic considerations for cognitive modeling,” accepted as a target article in Behavioral and Brain Sciences.
www.cambridge.org/core/journal...
@phaueis.bsky.social and I have had our paper, “Metabolic considerations for cognitive modeling,” accepted as a target article in Behavioral and Brain Sciences.
www.cambridge.org/core/journal...
Metabolic considerations for cognitive modeling | Behavioral and Brain Sciences | Cambridge Core
Metabolic considerations for cognitive modeling
www.cambridge.org
November 18, 2025 at 11:58 AM
#philsci #cogsky #CognitiveNeuroscience
@phaueis.bsky.social and I have had our paper, “Metabolic considerations for cognitive modeling,” accepted as a target article in Behavioral and Brain Sciences.
www.cambridge.org/core/journal...
@phaueis.bsky.social and I have had our paper, “Metabolic considerations for cognitive modeling,” accepted as a target article in Behavioral and Brain Sciences.
www.cambridge.org/core/journal...
Reposted by existwell
Lots of discussion of the cross-sectional, retrospective survey showing evidence for metaphysical belief change after psychedelic experiences...
(picture on left)
But few know of the better quality prospective longitudinal study showing NO evidence for belief change!
(picture on right)
(picture on left)
But few know of the better quality prospective longitudinal study showing NO evidence for belief change!
(picture on right)
November 13, 2025 at 9:50 PM
Lots of discussion of the cross-sectional, retrospective survey showing evidence for metaphysical belief change after psychedelic experiences...
(picture on left)
But few know of the better quality prospective longitudinal study showing NO evidence for belief change!
(picture on right)
(picture on left)
But few know of the better quality prospective longitudinal study showing NO evidence for belief change!
(picture on right)
Reposted by existwell
Dr. David Yaden will be speaking at MGH’s Psychedelics & Psychedelic Medicine Conference (Nov 14–15, virtual). Learn the latest research + earn CME/CE. Use code NET50 to save $50.
Register: lms.mghcme.org/VirtualPsych...
Register: lms.mghcme.org/VirtualPsych...
November 6, 2025 at 9:49 PM
Dr. David Yaden will be speaking at MGH’s Psychedelics & Psychedelic Medicine Conference (Nov 14–15, virtual). Learn the latest research + earn CME/CE. Use code NET50 to save $50.
Register: lms.mghcme.org/VirtualPsych...
Register: lms.mghcme.org/VirtualPsych...
Lots of discussion of the cross-sectional, retrospective survey showing evidence for metaphysical belief change after psychedelic experiences...
(picture on left)
But few know of the better quality prospective longitudinal study showing NO evidence for belief change!
(picture on right)
(picture on left)
But few know of the better quality prospective longitudinal study showing NO evidence for belief change!
(picture on right)
November 13, 2025 at 9:50 PM
Lots of discussion of the cross-sectional, retrospective survey showing evidence for metaphysical belief change after psychedelic experiences...
(picture on left)
But few know of the better quality prospective longitudinal study showing NO evidence for belief change!
(picture on right)
(picture on left)
But few know of the better quality prospective longitudinal study showing NO evidence for belief change!
(picture on right)
Reposted by existwell
New article published in
@jamahealthforum.com that examines and critiques 4 aspects of the current pathwork of regulations covering access to psychedelics––and then provides constructive, sensible, and actionable ways forward for each.
Work led by drug policy expert @caleighpropes.bsky.social
@jamahealthforum.com that examines and critiques 4 aspects of the current pathwork of regulations covering access to psychedelics––and then provides constructive, sensible, and actionable ways forward for each.
Work led by drug policy expert @caleighpropes.bsky.social
New today in JAMA Health Forum: Our team discusses how to fill policy gaps surrounding the use of psychedelics to treat mental health and substance use conditions, should they be approved by the US Food and Drug Administration.
Gaps in US Psychedelic Policy and How to Close Them | Health Policy - By @caleighpropes.bsky.social, @katherinecheung.bsky.social, Matthew Eisenberg, David Yaden | @jama.com Health Forum jamanetwork.com/journals/jam...
November 10, 2025 at 3:37 PM
New article published in
@jamahealthforum.com that examines and critiques 4 aspects of the current pathwork of regulations covering access to psychedelics––and then provides constructive, sensible, and actionable ways forward for each.
Work led by drug policy expert @caleighpropes.bsky.social
@jamahealthforum.com that examines and critiques 4 aspects of the current pathwork of regulations covering access to psychedelics––and then provides constructive, sensible, and actionable ways forward for each.
Work led by drug policy expert @caleighpropes.bsky.social
New paper led by CPCR postdoc Praachi Tiwari!
The psychedelic DOI alters locomotion depending on dose & species (thru 5-HT₂A receptors) aiding understanding anxiety-like behavior in animal models of psychedelics.
(w/ @viditavaidya.bsky.social and her great lab)
www.sciencedirect.com/science/arti...
The psychedelic DOI alters locomotion depending on dose & species (thru 5-HT₂A receptors) aiding understanding anxiety-like behavior in animal models of psychedelics.
(w/ @viditavaidya.bsky.social and her great lab)
www.sciencedirect.com/science/arti...
Acute DOI treatment evokes dose and species-dependent locomotor effects on the elevated plus maze
Recent evidence suggests that psychedelics hold promise in treating a range of neuropsychiatric disorders, highlighting the need to better understand …
www.sciencedirect.com
November 11, 2025 at 3:07 PM
New paper led by CPCR postdoc Praachi Tiwari!
The psychedelic DOI alters locomotion depending on dose & species (thru 5-HT₂A receptors) aiding understanding anxiety-like behavior in animal models of psychedelics.
(w/ @viditavaidya.bsky.social and her great lab)
www.sciencedirect.com/science/arti...
The psychedelic DOI alters locomotion depending on dose & species (thru 5-HT₂A receptors) aiding understanding anxiety-like behavior in animal models of psychedelics.
(w/ @viditavaidya.bsky.social and her great lab)
www.sciencedirect.com/science/arti...
New article published in
@jamahealthforum.com that examines and critiques 4 aspects of the current pathwork of regulations covering access to psychedelics––and then provides constructive, sensible, and actionable ways forward for each.
Work led by drug policy expert @caleighpropes.bsky.social
@jamahealthforum.com that examines and critiques 4 aspects of the current pathwork of regulations covering access to psychedelics––and then provides constructive, sensible, and actionable ways forward for each.
Work led by drug policy expert @caleighpropes.bsky.social
New today in JAMA Health Forum: Our team discusses how to fill policy gaps surrounding the use of psychedelics to treat mental health and substance use conditions, should they be approved by the US Food and Drug Administration.
Gaps in US Psychedelic Policy and How to Close Them | Health Policy - By @caleighpropes.bsky.social, @katherinecheung.bsky.social, Matthew Eisenberg, David Yaden | @jama.com Health Forum jamanetwork.com/journals/jam...
November 10, 2025 at 3:37 PM
New article published in
@jamahealthforum.com that examines and critiques 4 aspects of the current pathwork of regulations covering access to psychedelics––and then provides constructive, sensible, and actionable ways forward for each.
Work led by drug policy expert @caleighpropes.bsky.social
@jamahealthforum.com that examines and critiques 4 aspects of the current pathwork of regulations covering access to psychedelics––and then provides constructive, sensible, and actionable ways forward for each.
Work led by drug policy expert @caleighpropes.bsky.social
Reposted by existwell
New today in JAMA Health Forum: Our team discusses how to fill policy gaps surrounding the use of psychedelics to treat mental health and substance use conditions, should they be approved by the US Food and Drug Administration.
Gaps in US Psychedelic Policy and How to Close Them | Health Policy - By @caleighpropes.bsky.social, @katherinecheung.bsky.social, Matthew Eisenberg, David Yaden | @jama.com Health Forum jamanetwork.com/journals/jam...
Gaps in US Psychedelic Policy and How to Close Them
This Viewpoint discusses how to fill policy gaps surrounding the use of psychedelics to treat mental health and substance use conditions, should they be approved by the US Food and Drug Administration...
jamanetwork.com
November 7, 2025 at 9:36 PM
New today in JAMA Health Forum: Our team discusses how to fill policy gaps surrounding the use of psychedelics to treat mental health and substance use conditions, should they be approved by the US Food and Drug Administration.
Reposted by existwell
Citation impact and actual impact are not the same thing. What is the prototypical paper from the social-behavioral sciences that had both a huge citation impact and a huge actual (by your definition) impact?
Vote by naming a paper or liking someone else's nomination. One box filled per day.
Vote by naming a paper or liking someone else's nomination. One box filled per day.
November 5, 2025 at 2:33 PM
Citation impact and actual impact are not the same thing. What is the prototypical paper from the social-behavioral sciences that had both a huge citation impact and a huge actual (by your definition) impact?
Vote by naming a paper or liking someone else's nomination. One box filled per day.
Vote by naming a paper or liking someone else's nomination. One box filled per day.
Reposted by existwell
Join us at Johns Hopkins University in Baltimore, Maryland for an exceptional opportunity to work and train in psychedelic science and medicine.
Please share widely and apply if you qualify!
Please share widely and apply if you qualify!
Postdoctoral Fellowship Opportunity
We are looking for excellent MD Psychiatrist applicants to work & train at the CPCR at Johns Hopkins
@jhpsychedelics.bsky.social, the largest and most comprehensive psychedelic research program in the world.
Email Dr. Sandeep Nayak [email protected]
We are looking for excellent MD Psychiatrist applicants to work & train at the CPCR at Johns Hopkins
@jhpsychedelics.bsky.social, the largest and most comprehensive psychedelic research program in the world.
Email Dr. Sandeep Nayak [email protected]
November 4, 2025 at 4:54 PM
Join us at Johns Hopkins University in Baltimore, Maryland for an exceptional opportunity to work and train in psychedelic science and medicine.
Please share widely and apply if you qualify!
Please share widely and apply if you qualify!
Reposted by existwell
Next talk from the #NaturalPhilosophy Symposium is Simon DeDeo @simondedeo.bsky.social on Hard Proofs and Good Reasons, followed by commentary by Jeremy Goodman.
Next talk from the #NaturalPhilosophy Symposium is Jennifer Nagel on The Natural Structure of Common Knowledge, with commentary by Steven Gross.
www.youtube.com/watch?v=uEiQ...
www.youtube.com/watch?v=uEiQ...
November 4, 2025 at 4:31 PM
Next talk from the #NaturalPhilosophy Symposium is Simon DeDeo @simondedeo.bsky.social on Hard Proofs and Good Reasons, followed by commentary by Jeremy Goodman.
Reposted by existwell
For this week’s New Yorker (and in celebration of Halloween!), I wrote about how fictional monsters have gone from mean and horrendous to humanized and misunderstood.
In the past few decades, monsters have gone from menaces to misfits. Why do we feel the need to humanize them? https://newyorkermag.visitlink.me/ixYof5
October 31, 2025 at 8:48 PM
For this week’s New Yorker (and in celebration of Halloween!), I wrote about how fictional monsters have gone from mean and horrendous to humanized and misunderstood.
Postdoctoral Fellowship Opportunity
We are looking for excellent MD Psychiatrist applicants to work & train at the CPCR at Johns Hopkins
@jhpsychedelics.bsky.social, the largest and most comprehensive psychedelic research program in the world.
Email Dr. Sandeep Nayak [email protected]
We are looking for excellent MD Psychiatrist applicants to work & train at the CPCR at Johns Hopkins
@jhpsychedelics.bsky.social, the largest and most comprehensive psychedelic research program in the world.
Email Dr. Sandeep Nayak [email protected]
October 30, 2025 at 7:53 PM
Postdoctoral Fellowship Opportunity
We are looking for excellent MD Psychiatrist applicants to work & train at the CPCR at Johns Hopkins
@jhpsychedelics.bsky.social, the largest and most comprehensive psychedelic research program in the world.
Email Dr. Sandeep Nayak [email protected]
We are looking for excellent MD Psychiatrist applicants to work & train at the CPCR at Johns Hopkins
@jhpsychedelics.bsky.social, the largest and most comprehensive psychedelic research program in the world.
Email Dr. Sandeep Nayak [email protected]
Reposted by existwell
Psychedelics alter neurovascular coupling, which means we need to critically re-evaluate fMRI findings of acute psychedelic effects
#neuroskyence
#PsychSciSky
www.nature.com/articles/s41...
#neuroskyence
#PsychSciSky
www.nature.com/articles/s41...
Psychedelic 5-HT2A receptor agonism alters neurovascular coupling and differentially affects neuronal and hemodynamic measures of brain function - Nature Neuroscience
Padawer-Curry et al. show that the hallucinogenic 5-HT2A receptor agonist DOI alters neurovascular coupling in mice, with implications for the interpretation of human fMRI studies of psychedelics.
www.nature.com
October 27, 2025 at 7:07 PM
Psychedelics alter neurovascular coupling, which means we need to critically re-evaluate fMRI findings of acute psychedelic effects
#neuroskyence
#PsychSciSky
www.nature.com/articles/s41...
#neuroskyence
#PsychSciSky
www.nature.com/articles/s41...
On the second anniversary of Roland Griffiths' death, I'm taking the opportunity to reflect on the value of scientific curiosity and the virtue of constant curiosity about life in general that he seemed to me to so consistently embody.
October 21, 2025 at 9:09 PM
On the second anniversary of Roland Griffiths' death, I'm taking the opportunity to reflect on the value of scientific curiosity and the virtue of constant curiosity about life in general that he seemed to me to so consistently embody.
Reposted by existwell
It has been an absolute joy to learn from and engage with the brilliant @lilweb.bsky.social @rikepetzschner.bsky.social @danasmall.bsky.social. I am so proud of our collaboration on the future of #interoception and #RL. May you find as much inspiration in reading this paper as we did in writing it.
For the past couple of years I met weekly with 3 amazing younger scientists @lilweb.bsky.social @debyee.bsky.social @rikepetzschner.bsky.social to share ideas and teach each other. No agenda. It was often the favorite part of my week. Then we started writing. www.sciencedirect.com/science/arti...
The interoceptive origin of reinforcement learning
Rewards play a crucial role in sculpting all motivated behavior. Traditionally, research on reinforcement learning has centered on how rewards guide l…
www.sciencedirect.com
June 11, 2025 at 9:26 AM
It has been an absolute joy to learn from and engage with the brilliant @lilweb.bsky.social @rikepetzschner.bsky.social @danasmall.bsky.social. I am so proud of our collaboration on the future of #interoception and #RL. May you find as much inspiration in reading this paper as we did in writing it.
Reposted by existwell
Mindscape Ask Me Anything | October 2025. Hopefully this one answers once and for all why the universe isn't a black hole if it was so densely packed at early times. #MindscapePodcast
www.preposterousuniverse.com/podcast/2025...
www.preposterousuniverse.com/podcast/2025...
October 13, 2025 at 11:49 AM
Mindscape Ask Me Anything | October 2025. Hopefully this one answers once and for all why the universe isn't a black hole if it was so densely packed at early times. #MindscapePodcast
www.preposterousuniverse.com/podcast/2025...
www.preposterousuniverse.com/podcast/2025...
Reposted by existwell
🧠 New Psychedelic Article in Schizophrenia Bulletin!
We argue that visual hallucinations in psychedelics and Lewy body disease may share common mechanisms ⇒ visual degradation & cortical excitation.
academic.oup.com/schizophreni...
Excited to see this spark discussion!
#Neuroscience #Psychedelics
We argue that visual hallucinations in psychedelics and Lewy body disease may share common mechanisms ⇒ visual degradation & cortical excitation.
academic.oup.com/schizophreni...
Excited to see this spark discussion!
#Neuroscience #Psychedelics
Visual Hallucinations in Serotonergic Psychedelics and Lewy Body Diseases
AbstractBackground and Hypothesis. Visual hallucinations (VH) are a core symptom of both Lewy body diseases (LBDs; eg, Parkinson’s disease and dementia wit
academic.oup.com
October 6, 2025 at 5:32 PM
🧠 New Psychedelic Article in Schizophrenia Bulletin!
We argue that visual hallucinations in psychedelics and Lewy body disease may share common mechanisms ⇒ visual degradation & cortical excitation.
academic.oup.com/schizophreni...
Excited to see this spark discussion!
#Neuroscience #Psychedelics
We argue that visual hallucinations in psychedelics and Lewy body disease may share common mechanisms ⇒ visual degradation & cortical excitation.
academic.oup.com/schizophreni...
Excited to see this spark discussion!
#Neuroscience #Psychedelics
Reposted by existwell
Terrific framing of my work on "weirdness" by Ellie and David, before after and during their interview of me on Overthink. Probably the best engagement with that dimension of my work that I've seen so far.
podcasts.apple.com/us/podcast/w...
podcasts.apple.com/us/podcast/w...
Weirdness with Eric Schwitzgebel
Podcast Episode · Overthink · 07/15/2025 · 57m
podcasts.apple.com
August 4, 2025 at 4:18 PM
Terrific framing of my work on "weirdness" by Ellie and David, before after and during their interview of me on Overthink. Probably the best engagement with that dimension of my work that I've seen so far.
podcasts.apple.com/us/podcast/w...
podcasts.apple.com/us/podcast/w...
Reposted by existwell
New in Philosophical Psychology: Derek Anderson & I review Feltz & Cokely’s Diversity and Disagreement (OUP, 2024). We applaud their empirical rigor linking personality & philosophical views, but question their (to our minds) overly hasty and sweeping philosophical conclusions.🧵
September 29, 2025 at 4:38 PM
New in Philosophical Psychology: Derek Anderson & I review Feltz & Cokely’s Diversity and Disagreement (OUP, 2024). We applaud their empirical rigor linking personality & philosophical views, but question their (to our minds) overly hasty and sweeping philosophical conclusions.🧵
Reposted by existwell
We need heroes. People to respect and emulate. People who inspire us to do our best and be our best. Jane Goodall was a hero, and she will remain one.
October 2, 2025 at 1:18 PM
We need heroes. People to respect and emulate. People who inspire us to do our best and be our best. Jane Goodall was a hero, and she will remain one.