Eliver Ghosn
@eliverghosn.bsky.social
Immunologist | Associate Professor of Medicine and Pediatrics
Stanford ➡ Emory
Made in 🇧🇷 🇱🇧 🇺🇸 🏳️🌈
#BYourCell
Stanford ➡ Emory
Made in 🇧🇷 🇱🇧 🇺🇸 🏳️🌈
#BYourCell
Our new FlowLITE protocol for simultaneously quantifying all (human and mouse) #antibody isotypes in a single tube using #flowcytometry is out in STAR Protocols: star-protocols.cell.com/protocols/4572
Is it time to retire the ELISAs for #antibody measurements?
1/4
Is it time to retire the ELISAs for #antibody measurements?
1/4
November 18, 2025 at 7:20 PM
Our new FlowLITE protocol for simultaneously quantifying all (human and mouse) #antibody isotypes in a single tube using #flowcytometry is out in STAR Protocols: star-protocols.cell.com/protocols/4572
Is it time to retire the ELISAs for #antibody measurements?
1/4
Is it time to retire the ELISAs for #antibody measurements?
1/4
Main dish or Appetizer
1. Adas Polo & Lamb (Fatemeh Yousefian and Masoud Ilkhani)
2. Lasagna Bolognese (Alex Nazzari & Matt Stern)
Dessert
1. Mohanthal (Hardy Nariya)
2. Cesta di Frutta @katyely.bsky.social
1. Adas Polo & Lamb (Fatemeh Yousefian and Masoud Ilkhani)
2. Lasagna Bolognese (Alex Nazzari & Matt Stern)
Dessert
1. Mohanthal (Hardy Nariya)
2. Cesta di Frutta @katyely.bsky.social
November 18, 2025 at 6:45 PM
Main dish or Appetizer
1. Adas Polo & Lamb (Fatemeh Yousefian and Masoud Ilkhani)
2. Lasagna Bolognese (Alex Nazzari & Matt Stern)
Dessert
1. Mohanthal (Hardy Nariya)
2. Cesta di Frutta @katyely.bsky.social
1. Adas Polo & Lamb (Fatemeh Yousefian and Masoud Ilkhani)
2. Lasagna Bolognese (Alex Nazzari & Matt Stern)
Dessert
1. Mohanthal (Hardy Nariya)
2. Cesta di Frutta @katyely.bsky.social
Our 🌈 Annual Cook-off event keeps growing! We build community around great food, drinks, and music. Thank you for the delicious dishes and fantastic company.
The 2025 Chef Laureate goes to...
The 2025 Chef Laureate goes to...
November 18, 2025 at 6:45 PM
Our 🌈 Annual Cook-off event keeps growing! We build community around great food, drinks, and music. Thank you for the delicious dishes and fantastic company.
The 2025 Chef Laureate goes to...
The 2025 Chef Laureate goes to...
We also hosted a Herzenberg-style lab meeting between our lab and Rabin Tirouvanziam's (we both left Stanford to join the Emory faculty). We celebrated three generations of scientists from the Herzenberg family 😊
May 16, 2025 at 7:11 PM
We also hosted a Herzenberg-style lab meeting between our lab and Rabin Tirouvanziam's (we both left Stanford to join the Emory faculty). We celebrated three generations of scientists from the Herzenberg family 😊
This week, we celebrated an extraordinary scientist, my mentor, Lee Herzenberg. She received an honorary degree (with Usher :). We hosted a symposium in her honor with Max Cooper, alumni, and others. I was thrilled to share her incredible story with the young generation @emoryuniversity.bsky.social.
May 16, 2025 at 7:11 PM
This week, we celebrated an extraordinary scientist, my mentor, Lee Herzenberg. She received an honorary degree (with Usher :). We hosted a symposium in her honor with Max Cooper, alumni, and others. I was thrilled to share her incredible story with the young generation @emoryuniversity.bsky.social.
I had the honor of being nominated by Justin as the faculty member of "greatest influence" for his election to the Phi Beta Kappa Academy. It was a great ceremony! 🎉Congratulations, Justin, and best of luck in medical school!
April 11, 2025 at 5:41 PM
I had the honor of being nominated by Justin as the faculty member of "greatest influence" for his election to the Phi Beta Kappa Academy. It was a great ceremony! 🎉Congratulations, Justin, and best of luck in medical school!
I had the honor to be nominated by Justin as the faculty of "greatest influence" for his election to the Phi Beta Kappa Academy. It was a great ceremony! 🎉Congratulations, Justin! And best of luck in medical school!
April 11, 2025 at 5:40 PM
I had the honor to be nominated by Justin as the faculty of "greatest influence" for his election to the Phi Beta Kappa Academy. It was a great ceremony! 🎉Congratulations, Justin! And best of luck in medical school!
We are #Hiring! Please share!
#ImmunoSky 🧪
Join our multi-disciplinary B-cell team @Emory/ATL to lead exciting projects on human immunology funded by the Gates Foundation and the NIH (Position fully funded and not dependent on future grants).
ghosnlab.science/join-us
#BYourCell
#ImmunoSky 🧪
Join our multi-disciplinary B-cell team @Emory/ATL to lead exciting projects on human immunology funded by the Gates Foundation and the NIH (Position fully funded and not dependent on future grants).
ghosnlab.science/join-us
#BYourCell
April 4, 2025 at 10:14 PM
We are #Hiring! Please share!
#ImmunoSky 🧪
Join our multi-disciplinary B-cell team @Emory/ATL to lead exciting projects on human immunology funded by the Gates Foundation and the NIH (Position fully funded and not dependent on future grants).
ghosnlab.science/join-us
#BYourCell
#ImmunoSky 🧪
Join our multi-disciplinary B-cell team @Emory/ATL to lead exciting projects on human immunology funded by the Gates Foundation and the NIH (Position fully funded and not dependent on future grants).
ghosnlab.science/join-us
#BYourCell
Congratulations to Justin Hahm on his impressive Honors Thesis. Highest Honors! 🎉🍾
Justin joined us as a freshman to develop FlowLITE: a technology to quantify and characterize human antibody isotypes using Flow Cytometry. He used it to show humans produce natural IgA1 before birth! #BYourCell
Justin joined us as a freshman to develop FlowLITE: a technology to quantify and characterize human antibody isotypes using Flow Cytometry. He used it to show humans produce natural IgA1 before birth! #BYourCell
April 4, 2025 at 6:11 PM
Congratulations to Justin Hahm on his impressive Honors Thesis. Highest Honors! 🎉🍾
Justin joined us as a freshman to develop FlowLITE: a technology to quantify and characterize human antibody isotypes using Flow Cytometry. He used it to show humans produce natural IgA1 before birth! #BYourCell
Justin joined us as a freshman to develop FlowLITE: a technology to quantify and characterize human antibody isotypes using Flow Cytometry. He used it to show humans produce natural IgA1 before birth! #BYourCell
1/4
Today, I honor Dr. Lee Herzenberg, a renaissance woman and a pioneer.
#InternationalWomensDay #WomenInScience #IWD
I’ve been fortunate to be mentored by women at home and in science. I met Lee in 2004, and her mentorship profoundly influenced my career and values.
Today, I honor Dr. Lee Herzenberg, a renaissance woman and a pioneer.
#InternationalWomensDay #WomenInScience #IWD
I’ve been fortunate to be mentored by women at home and in science. I met Lee in 2004, and her mentorship profoundly influenced my career and values.
March 9, 2025 at 8:17 PM
1/4
Today, I honor Dr. Lee Herzenberg, a renaissance woman and a pioneer.
#InternationalWomensDay #WomenInScience #IWD
I’ve been fortunate to be mentored by women at home and in science. I met Lee in 2004, and her mentorship profoundly influenced my career and values.
Today, I honor Dr. Lee Herzenberg, a renaissance woman and a pioneer.
#InternationalWomensDay #WomenInScience #IWD
I’ve been fortunate to be mentored by women at home and in science. I met Lee in 2004, and her mentorship profoundly influenced my career and values.
Celebration after his defense!
January 14, 2025 at 6:25 PM
Celebration after his defense!
He is now Dr. Babcock! Beautiful PhD defense under heavy snow in ATL!
Ben presented his surprising findings on the seemingly protective role of nasal autoantibodies in COVID-19. And his work developing new multi-omics scRNA-seq to study human B cells!
Congratulations, Dr! Well-deserved PhD title!
Ben presented his surprising findings on the seemingly protective role of nasal autoantibodies in COVID-19. And his work developing new multi-omics scRNA-seq to study human B cells!
Congratulations, Dr! Well-deserved PhD title!
January 13, 2025 at 5:27 PM
He is now Dr. Babcock! Beautiful PhD defense under heavy snow in ATL!
Ben presented his surprising findings on the seemingly protective role of nasal autoantibodies in COVID-19. And his work developing new multi-omics scRNA-seq to study human B cells!
Congratulations, Dr! Well-deserved PhD title!
Ben presented his surprising findings on the seemingly protective role of nasal autoantibodies in COVID-19. And his work developing new multi-omics scRNA-seq to study human B cells!
Congratulations, Dr! Well-deserved PhD title!
🎉 PhD defense today at 2pm EST! With or without snow ❄️, join us at Winship to hear Ben Babcock's beautiful and surprising study on the seemingly protective role of nasal autoantibodies in COVID-19! If we can't make it to Emory, we will proceed with the public defense on Zoom.
#BYourCell #ImmunoSky
#BYourCell #ImmunoSky
January 10, 2025 at 4:11 PM
🎉 PhD defense today at 2pm EST! With or without snow ❄️, join us at Winship to hear Ben Babcock's beautiful and surprising study on the seemingly protective role of nasal autoantibodies in COVID-19! If we can't make it to Emory, we will proceed with the public defense on Zoom.
#BYourCell #ImmunoSky
#BYourCell #ImmunoSky
❄️🥶 This is the heaviest snow day in Atlanta since I moved here in 2017! It is beautiful outside! But that means the city stops, even though today is a special day for our lab...
January 10, 2025 at 4:00 PM
❄️🥶 This is the heaviest snow day in Atlanta since I moved here in 2017! It is beautiful outside! But that means the city stops, even though today is a special day for our lab...
It’s been a great year!
Happy holidays from 5 Emory labs! This year we celebrated with friends from Luisa Cervantes-Barragan, Byron Au-Yeung, Chaoran Li, and Matt Woodruff’s labs! Much fun. I’m grateful to work with great people.
Happy holidays from 5 Emory labs! This year we celebrated with friends from Luisa Cervantes-Barragan, Byron Au-Yeung, Chaoran Li, and Matt Woodruff’s labs! Much fun. I’m grateful to work with great people.
December 20, 2024 at 10:21 PM
It’s been a great year!
Happy holidays from 5 Emory labs! This year we celebrated with friends from Luisa Cervantes-Barragan, Byron Au-Yeung, Chaoran Li, and Matt Woodruff’s labs! Much fun. I’m grateful to work with great people.
Happy holidays from 5 Emory labs! This year we celebrated with friends from Luisa Cervantes-Barragan, Byron Au-Yeung, Chaoran Li, and Matt Woodruff’s labs! Much fun. I’m grateful to work with great people.
🧵6/9 Key Finding 4
Protective Autoantibodies? Contrary to the belief that anti-IFN-α autoantibodies are harmful, nasal IgA1 autoantibodies were associated with fewer symptoms, less systemic inflammation, and robust anti-SARS-CoV-2 antibodies in the nose.
Protective Autoantibodies? Contrary to the belief that anti-IFN-α autoantibodies are harmful, nasal IgA1 autoantibodies were associated with fewer symptoms, less systemic inflammation, and robust anti-SARS-CoV-2 antibodies in the nose.
November 17, 2024 at 1:14 AM
🧵6/9 Key Finding 4
Protective Autoantibodies? Contrary to the belief that anti-IFN-α autoantibodies are harmful, nasal IgA1 autoantibodies were associated with fewer symptoms, less systemic inflammation, and robust anti-SARS-CoV-2 antibodies in the nose.
Protective Autoantibodies? Contrary to the belief that anti-IFN-α autoantibodies are harmful, nasal IgA1 autoantibodies were associated with fewer symptoms, less systemic inflammation, and robust anti-SARS-CoV-2 antibodies in the nose.
🧵5/9 Key Finding 3
Anti-IFN-α Autoantibodies Peak after Host IFN-α: Only patients who produced nasal IFN-α developed nasal IgA1 anti-IFN-α. We showed a regulated balance between viral load and subsequent peak IFN-α followed by peak anti-IFN-α.
Anti-IFN-α Autoantibodies Peak after Host IFN-α: Only patients who produced nasal IFN-α developed nasal IgA1 anti-IFN-α. We showed a regulated balance between viral load and subsequent peak IFN-α followed by peak anti-IFN-α.
November 17, 2024 at 1:14 AM
🧵5/9 Key Finding 3
Anti-IFN-α Autoantibodies Peak after Host IFN-α: Only patients who produced nasal IFN-α developed nasal IgA1 anti-IFN-α. We showed a regulated balance between viral load and subsequent peak IFN-α followed by peak anti-IFN-α.
Anti-IFN-α Autoantibodies Peak after Host IFN-α: Only patients who produced nasal IFN-α developed nasal IgA1 anti-IFN-α. We showed a regulated balance between viral load and subsequent peak IFN-α followed by peak anti-IFN-α.
🧵4/9 Key Finding 2
Blood Autoantibodies are Separate from the Nasal and Associated with Worse Prognosis: Only a third of the patients developed blood anti-IFN-α, which appeared later and were IgG1. Systemic IgG1 persisted and was associated with higher systemic inflammation and worse symptoms.
Blood Autoantibodies are Separate from the Nasal and Associated with Worse Prognosis: Only a third of the patients developed blood anti-IFN-α, which appeared later and were IgG1. Systemic IgG1 persisted and was associated with higher systemic inflammation and worse symptoms.
November 17, 2024 at 1:14 AM
🧵4/9 Key Finding 2
Blood Autoantibodies are Separate from the Nasal and Associated with Worse Prognosis: Only a third of the patients developed blood anti-IFN-α, which appeared later and were IgG1. Systemic IgG1 persisted and was associated with higher systemic inflammation and worse symptoms.
Blood Autoantibodies are Separate from the Nasal and Associated with Worse Prognosis: Only a third of the patients developed blood anti-IFN-α, which appeared later and were IgG1. Systemic IgG1 persisted and was associated with higher systemic inflammation and worse symptoms.
🧵3/9 Key Finding 1
Viral-induced and Transient Nasal IgA1 anti-IFN-α: More than 70% of mild and moderate cases developed nasal IgA1 anti-IFN-α (after the first PCR+ test), which waned as the patients recovered. Importantly, unlike SARS-CoV-2, mRNA vaccination did not induce anti-IFN-α in the nose.
Viral-induced and Transient Nasal IgA1 anti-IFN-α: More than 70% of mild and moderate cases developed nasal IgA1 anti-IFN-α (after the first PCR+ test), which waned as the patients recovered. Importantly, unlike SARS-CoV-2, mRNA vaccination did not induce anti-IFN-α in the nose.
November 17, 2024 at 1:14 AM
🧵3/9 Key Finding 1
Viral-induced and Transient Nasal IgA1 anti-IFN-α: More than 70% of mild and moderate cases developed nasal IgA1 anti-IFN-α (after the first PCR+ test), which waned as the patients recovered. Importantly, unlike SARS-CoV-2, mRNA vaccination did not induce anti-IFN-α in the nose.
Viral-induced and Transient Nasal IgA1 anti-IFN-α: More than 70% of mild and moderate cases developed nasal IgA1 anti-IFN-α (after the first PCR+ test), which waned as the patients recovered. Importantly, unlike SARS-CoV-2, mRNA vaccination did not induce anti-IFN-α in the nose.
🧵2/9 Study Overview:
We developed FlowBEAT to track all eight human antibody isotypes (IgG1-4, IgA1-2, IgM, IgE) against IFN-α subtypes and SARS-CoV-2 proteins over 20 months in the airways and blood of 125 patients with varying disease severity. FlowBEAT distinguished mild, moderate, and severe.
We developed FlowBEAT to track all eight human antibody isotypes (IgG1-4, IgA1-2, IgM, IgE) against IFN-α subtypes and SARS-CoV-2 proteins over 20 months in the airways and blood of 125 patients with varying disease severity. FlowBEAT distinguished mild, moderate, and severe.
November 17, 2024 at 1:14 AM
🧵2/9 Study Overview:
We developed FlowBEAT to track all eight human antibody isotypes (IgG1-4, IgA1-2, IgM, IgE) against IFN-α subtypes and SARS-CoV-2 proteins over 20 months in the airways and blood of 125 patients with varying disease severity. FlowBEAT distinguished mild, moderate, and severe.
We developed FlowBEAT to track all eight human antibody isotypes (IgG1-4, IgA1-2, IgM, IgE) against IFN-α subtypes and SARS-CoV-2 proteins over 20 months in the airways and blood of 125 patients with varying disease severity. FlowBEAT distinguished mild, moderate, and severe.