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eLife
@elife.bsky.social
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The funder-researcher collaboration and open-access publisher for research in the life and biomedical sciences.

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elife.bsky.social
eLife is an independent nonprofit committed to improving the way research is communicated.

We do this through our innovative publishing model, developing open source technologies and community initiatives to improve research culture.

Be a part of it: buff.ly/TDDXVhZ
December 2, 2025 at 4:11 PM
elife.bsky.social
Jumping spiders can recognise one another. This ability to learn, remember and represent images is quite surprising for such a tiny-brained animal!
buff.ly/dCkwPr0
November 29, 2025 at 11:01 AM
elife.bsky.social
New work reveals Gyc76C as the receptor for the anti-diuretic hormone ITPa in flies, uncovering how it helps control hydration and metabolic balance.
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November 28, 2025 at 9:02 PM
elife.bsky.social
eLife assessments are a new evaluation tool for research. They are designed to provide readers with richer and more nuanced assessments of articles than binary publishing decisions.

Learn how we write them: buff.ly/10CDKWp
November 28, 2025 at 2:59 PM
elife.bsky.social
This study presents new tools for measuring the intracellular calcium concentration close to transmitter release sites, which may be relevant for synaptic vesicle fusion and replenishment.
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November 28, 2025 at 9:21 AM
elife.bsky.social
Two rainforest butterflies have evolved to look more alike, likely to confuse shared predators. But why don’t they get confused themselves?

To avoid mating with the wrong species, they’ve cleverly evolved distinct scents.
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November 27, 2025 at 11:28 PM
elife.bsky.social
This ‘fundamental’ study uncovers how directing pyruvate into mitochondria can shrink cells by shifting their metabolism away from building amino acids and proteins.
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November 26, 2025 at 4:15 PM
elife.bsky.social
Using an elegant single-cell RNA-seq analysis approach, researchers show that the gene Eed is essential for guiding facial bone formation and early tissue growth.
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November 26, 2025 at 11:01 AM
elife.bsky.social
1/ This Review Article from our new Focus Issue outlines how #epigenetic and metabolic rewiring enables innate immune cells to ‘remember’ past challenges, shaping protection, pathology, and new therapeutic strategies.
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Triggers of trained immunity across all tissues.
November 25, 2025 at 9:01 PM
elife.bsky.social
Evidence from 14 research funding programmes confirms that early winners tend to keep winning (Matthew effect). But the idea that an early setback makes you stronger later doesn’t replicate widely.
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eLife Assessment This important study reports the results of efforts to replicate two phenomena of significant interest to early-career scientists and scientific policymakers: the Matthew effect and the early-career setback effect. Several previous studies of these effects have focused on early-career researchers with grant proposals that fell just below or just above a funding threshold. Those just above the threshold were more likely to be successful when they applied for funding later in the career (an example of the well-known Matthew effect), while those just below were more likely to go on to have stronger publication records (the early-career setback effect). In this study the Matthew effect was found to be robust across funders, and to generalize from those close to the funding threshold to the whole population. The early-career setback effect was not robust across funders and did not generalize to the whole population. The evidence reported is convincing.
November 25, 2025 at 11:02 AM
elife.bsky.social
We have an amazing opportunity for Early-Career Researchers to join our Board of Directors!

We're looking for someone with experience in leading #OpenScience projects to support and lead eLife in our mission to change research communication.

🔗 buff.ly/SZgtgVv
November 24, 2025 at 9:02 PM
elife.bsky.social
Kinesin-1-driven microtubule sliding helps pancreatic β cells reorganise their cytoskeleton in response to glucose.
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November 23, 2025 at 11:28 PM
elife.bsky.social
Jumping spiders can recognise one another. This ability to learn, remember and represent images is quite surprising for such a tiny-brained animal!
buff.ly/dCkwPr0
November 23, 2025 at 11:01 AM
elife.bsky.social
The pathogenic bacteria Shigella avoids detection inside host cells by degrading RNF213, the protein responsible for sensing the presence of intracellular pathogens.

Read more in the eLife Insight Article: buff.ly/1mIc6m0
November 23, 2025 at 9:21 AM
elife.bsky.social
Elevated DNA damage without signs of ageing in the short-sleeping Mexican cavefish offers a unique model to study sleep, DNA repair, and ageing.
buff.ly/6VrO19l
November 21, 2025 at 9:01 PM
elife.bsky.social
Working on a replication study? Publish it with eLife.

We publish Replication Studies as part of our commitment to reproducibility and transparency in science.
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November 21, 2025 at 2:59 PM
elife.bsky.social
Engineered “migrasomes” show promise as a stable, room-temperature vaccine platform, triggering strong immune responses in mice and potentially easing cold-chain challenges.
buff.ly/9FZbeg2
November 21, 2025 at 9:21 AM
elife.bsky.social
Toxoplasma gondii carefully balances calcium between its organelles. This study shows the ER, via the SERCA pump, is central to controlling Ca²⁺ in the cytosol and mitochondria.

🔗 buff.ly/RFgcZgE
November 20, 2025 at 11:28 PM
elife.bsky.social
In the latest episode of the Enago podcast, our Head of Publishing, Fiona Hutton, talks about rethinking research dissemination with host Andrew Smith.

🔗 You can catch up on the conversation here: buff.ly/p7fjcz2
November 20, 2025 at 9:01 PM
elife.bsky.social
1/ This Review Article from our Trained Immunity Focus Issue explores how inflammatory cues imprint long-lasting memory on haematopoietic stem cells, reshaping innate defences through conserved transcriptional programmes.
elifesciences.org/reviewed-pre...
November 20, 2025 at 2:44 PM
elife.bsky.social
1/ Helminth-derived products are emerging as tools to rebalance immunity, with new insights into how their diverse molecules imprint trained immunity to counter inflammation.

Read more in this Review Article from our Trained Immunity Focus Issue: elifesciences.org/articles/105...
The interplay between gut microbiota, immune system, and environmental factors.
November 19, 2025 at 11:28 PM
elife.bsky.social
Animals seamlessly combine what they see and hear. This study presents a simple, biologically inspired model that predicts how visual and auditory cues are integrated across humans, monkeys, and rats.

🔗 buff.ly/HfMDRkH
November 19, 2025 at 4:15 PM
elife.bsky.social
🔬 October's most-read cancer biology paper maps colorectal cancer in mice, revealing tumour “neighbourhoods” that mirror human disease and could guide treatment: buff.ly/yf6ZdcG

Have a paper people should see? See what our Editors look for: buff.ly/8K9uocg
November 19, 2025 at 11:52 AM
elife.bsky.social
Not all plants spring forward with warmer temperatures. A new metric, phenological lag, shows how chilling, day length, and stress can slow leafing and flowering.
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November 17, 2025 at 9:01 PM
elife.bsky.social
Going to #SfN25 this year?

Find our Editor-in-Chief, Timothy Behrens, in room 4 for broad discussions on innovations in publishing: buff.ly/nF33AGT

#OpenScience #PhDChat #AcademicSky #ScholComm
November 17, 2025 at 5:28 PM